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Animal model developed to study accelerated atherosclerosis in diabetics
An animal model for diabetes that mimics human diabetics' dramatically accelerated rate of cardiovascular disease has been developed by researchers at the Medical College of Georgia. Researchers say the swine with their uncanny humanlike response to diabetes will provide insight into why human diabetics acquire and die from coronary artery disease and generalized atherosclerosis at two to six times the rate of non-diabetics. (2001-07-03)

Location of ulcerations in diabetic patients may be explained by blood flow
Arterial circulation may assist with patients diagnosed with peripheral neuropathy. (2003-04-09)

Nutritious new low-sugar juice targeted for diabetics, individuals with high blood sugar
Scientists in China are reporting development of a low-calorie, low-sugar vegetable juice custom-designed for millions of individuals with diabetes and pre-diabetic conditions that involve abnormally high blood sugar. Research on the new drink is scheduled for presentation in March at the 237th national meeting of the American Chemical Society. (2009-03-26)

Study links hypoxemia from obstructive sleep apnea with renal complications in type 2 diabetes
Examining the poorly understood link between obstructive sleep apnea (OSA) and type 2 diabetes complications, researchers identified specific measures of low blood oxygenation that are associated with impaired kidney function and diabetic nephropathy. The study by Linong Ji, M.D., and colleagues, Peking University People's Hospital and Peking University Health Science Center, is published in Diabetes Technology & Therapeutics. (2016-04-22)

Annals of Internal Medicine, tip sheet, March 19, 2002
Articles include (2002-03-18)

Diabetes identified as a risk factor for surgical site infections
Diabetic patients are at considerably increased risk for developing surgical site infections while undergoing most types of surgeries, compared to non-diabetic patients, according to a new study published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. (2015-10-27)

Avandia® may reduce risk of cardiovascular disease
The oral anti-diabetes drug Avandia® (rosiglitazone maleate) may decrease the risk of cardiovascular disease, the leading cause of death in the United States, according to data presented at the American Diabetes Association's 61st Scientific Sessions. (2001-06-26)

Studies covering 11 million patients show diabetic women around 40 percent more likely to suffer severe heart problems than diabetic men
A systematic review and meta-analysis of 19 studies containing almost 11 million patients shows that diabetic women are around 40 percent more likely to suffer acute coronary syndromes (heart attack or angina) than diabetic men. The study is presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) in Stockholm. (2015-09-14)

MSU researcher links diabetic complication, nerve damage in bone marrow
A research team led by a Michigan State University professor has discovered a link between diabetes and bone marrow nerve damage that may help treat one of the disease's most common and potentially blindness-causing complications. (2010-01-06)

GEN reports on ocular therapeutics targeting the retina
Therapies for retinal diseases are expected to overtake those for glaucoma by 2014, reports Genetic Engineering & Biotechnology News (GEN). (2012-09-10)

Wayne State discovers potential treatment for skin and corneal wound healing in diabetics
A team of Wayne State University researchers recently developed several diabetic models to study impaired wound healing in diabetic corneas. Using a genome-wide cDNA array analysis, the group identified genes, their associated pathways and the networks affected by DM in corneal epithelial cells and their roles in wound closure. Their findings may bring scientists one step closer to developing new treatments that may slow down or thwart the impact on vision. (2013-12-12)

New Iowa State research holds promise for diabetics with vitamin D deficiency
A simple change in diet could boost vitamin D levels for millions of Americans suffering from Type 2 diabetes, according to new research from Iowa State University published in the Journal of Agricultural and Food Chemistry. (2016-02-09)

USC Eye Institute study finds African-Americans at higher risk for diabetic vision loss
Research demonstrates that African-Americans bear heavier burden of diabetic macular edema due to problems with access to care. The study points to a need for improved screening and greater attention to vision loss by clinicians and patients. (2014-08-20)

Understanding where patients live can improve patient health
Family physicians typically don't consider where patients live when assessing their health care needs, despite research that indicates a person's environment can significantly affect their health. With the emergence of value-based health care, there are more incentives for providers to take those factors into account. However, a new study found that family physicians could not accurately estimate where their patients actually live. (2019-08-13)

New treatment targets found for blinding retinal disease
When the eye isn't getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists have identified new points where they may be able to calm the frenzy and instead enable recovery. (2020-08-10)

Joslin research boosts evidence for a new class of treatments to help preserve vision
Edward P. Feener, Ph.D., investigator in the Section on Vascular Cell Biology at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School, has shown that a substantial percentage of patients with DME do not have high levels of VEGF in the fluid inside their eyes but do have high levels of a protein called PKal (plasma kallikrein) and associated molecules that are key players in an inflammatory molecular pathway involved in the disease. (2015-05-19)

Scientists unravel brain-hormone circuit that helps police diabetes, female fertility
New findings by UT Southwestern Medical Center researchers suggest that the hormones leptin and insulin work together in specific neurons in the hypothalamus region of the brain to affect both the regulation of blood sugar levels in the body and, surprisingly, female fertility. (2010-04-07)

Understanding aspirin's effect on wound healing offers hope for treating chronic wounds
In addition to its known capacity to promote bleeding events, aspirin also inhibits wound healing. Researchers now describe how aspirin acts on key skin cells called keratinocytes, delaying skin repair at wound sites. A better understanding of this process offers hope for the development of drugs to encourage wounds to heal. (2014-05-12)

New 10-year risk predictors identified for liver related
A study presented today at the International Liver CongressTM 2013 -- which evaluated the relationship between non-alcoholic fatty liver disease (NAFLD), early predictors of atherosclerosis and the 10-year Framingham risk score -- showed that NAFLD increases the risk of early atherosclerotic lesions independent of established cardiovascular risk factors. (2013-04-26)

Joint Warwick study wins RCGP's Research Paper of the Year
Researchers from the University of Warwick have won a prestigious award for their work on diabetes. (2015-10-22)

Malfunctioning bone marrow cells sabotage nerve cells in diabetes
Malfunctioning bone marrow cells that produce insulin appear to cause a dangerous nerve condition called neuropathy that disables many people with diabetes, said a research team led by Baylor College of Medicine in Houston. (2005-08-22)

Digital tablets improve speed and ease of reading for people with moderate vision loss
People who have eye diseases that damage their central vision can regain the ability to read quickly and comfortably by using digital tablets, according to a recent study. The research found that people with moderate vision loss could increase their reading speed by 15 words-per-minute, on average. Using a tablet with a back-lit screen resulted in the fastest reading speeds for all study participants, no matter what their level of visual acuity. (2012-11-11)

Xenotransplantation as a therapy for type 1 diabetes
Transplantation of a whole pancreas or isolated insulin-producing beta cells are the only therapy to cure type I diabetes. However, the shortage of organ donors limits this approach to only few patients. LMU researchers have now shown that beta cells from genetically modified pigs can effectively restore pancreas function and can protect porcine beta cells from immune rejection in animal models. (2012-04-23)

American College of Foot and Ankle Surgeons 2003 Meeting
The American College of Foot and Ankle Surgeons invites you to cover its upcoming annual scientific meeting, February 20-23 in Orlando, at the Walt Disney World Swan and Dolphin Hotel. The meeting is the premier forum covering new developments and clinical practice trends in the surgical care of the foot and ankle. (2003-01-23)

$5.9 million grant to University of California San Diego for paradigm-shifting diabetes research
Kumar Sharma, M.D., FAHA, professor of medicine at the University of California, San Diego School of Medicine and director of the Center for Renal Translational Medicine, has received a $5.9 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, to study kidney complications related to type 1 and type 2 diabetes. (2011-09-30)

Procedure cures some diabetic mice, but not in the way previously reported
Researchers attempting to reproduce a controversial 2003 mouse experiment suggestive of a cure for type 1 diabetes have found evidence that the experimental procedure does eliminate diabetic symptoms in a small fraction of the mice exposed to it. However, scientists from Washington University School of Medicine in St. Louis found no signs that the procedure was working in the manner reported by the group of scientists at Harvard University who originated it. (2006-03-23)

Understanding the autoimmune response in type 1 diabetes
In the February 2 issue of the JCI, Mark Peakman and colleagues from King's College London suggest a mechanism for the specificity of immune response regulation that explains why the antigens present on pancreatic beta cells that activate T cells in both patients with type 1 diabetes mellitus and normal individuals, cause autoimmune-mediated destruction of insulin-secreting pancreatic beta cells in type 1 diabetes patients, but no such response in normal individuals. (2004-02-02)

HBOT for diabetic foot: Hint of benefit for wound closure
Additional hyperbaric oxygen therapy can promote the healing of wounds. In contrast, neither hints of advantages nor of disadvantages have been shown for other aspects of Treatment. (2016-07-06)

Efforts to replicate controversial diabetes therapy bring partial success
Researchers at the University of Chicago have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but is a set back for those who hoped to cure established diabetes by using stem cells from donor spleens to help patients grow new pancreatic islets. (2006-03-23)

Surgery achieves better long-term control of type 2 diabetes than standard therapy
Metabolic or bariatric surgery may be more effective than standard medical treatments for the long-term control of type 2 diabetes in obese patients, according to a new study by King's College London and the Universita Cattolica in Rome, Italy. The study, published in the Lancet, is the first to provide data on five-year outcomes of surgery from a randomized clinical trial specifically designed to compare this new approach against standard medical therapy for the treatment of type 2 diabetes. (2015-09-03)

Tecnalia develops a bioadhesive gel for the treatment of diabetic foot ulcers
The College of Pharmacy of the University of Barcelona, Ojer Pharma Laboratories and Tecnalia are jointly collaborating on the project, PRODERMA: 'Coorperative Development of a Sustained Release Matrix for the Treatment of Diabetic Foot Ulcers.' The project seeks to improve the effectiveness of conventional topical treatments through the application of an innovative technique in the topical media and administration of active ingredients. (2016-04-16)

Study reports success in treating a rare retinal disorder
Patients with a rare, blinding eye disease saw their vision improve after treatment with drugs to suppress their immune systems, according to researchers at the University of Michigan Kellogg Eye Center. (2009-04-13)

Erectile dysfunction treatments do not appear to damage vision over 6 months
Two medications used to treat erectile dysfunction in men (tadalafil and sildenafil) do not appear to have visual side effects when taken daily for six months, despite concerns about eye-related complications, according to a report in the April issue of Archives of Ophthalmology, one of the JAMA/Archives journals. (2009-04-13)

UConn biomedical engineer creates 'smart' bandages to heal chronic wounds
A new 'smart bandage' developed at UConn could help improve clinical care for people with chronic wounds. (2020-02-13)

Joslin researchers find key mechanism in increased atherosclerosis risk for people with diabetes
Researchers at Joslin Diabetes Center have discovered that when excessive PKC beta is found in the endothelium, the thin layer of cells that line blood vessels, atherosclerosis is exacerbated. This finding may lead to the development of treatments to reduce CVD risk in patients with both type 1 and type 2 diabetes. (2013-07-10)

Eating disorders more common among girls with diabetes
Eating disorders are almost twice as common in girls with type 1 diabetes as in non-diabetic girls of the same age, putting them at increased risk of complications, according to a study in this week's British Medical Journal. (2000-06-07)

Oxygen restrictions can be eased for premature infants with blinding eye disease
Modest supplemental oxygen given to premature infants with moderate cases of ROP, a potentially blinding eye disorder, may not improve ROP, but definitely does not make it worse. The results mean that clinicians do not have to be as restrictive as they have been when giving supplemental oxygen to infants who have already developed moderate ROP. These findings appear in a scientific paper published in the February issue of Pediatrics. (2000-02-06)

Improving eye patient care with telemedicine standards
Computer scientists at the National Institute of Standards and Technology (NIST) have teamed up with a group of medical professionals to advance the use of telemedicine. NIST and the American Telemedicine Association developed technical standards related to the diagnosis and treatment of diabetic retinopathy, which is a complication of diabetes and a leading cause of blindness. (2004-04-23)

UT Southwestern launches study of surgical option for treating diabetic and other neuropathies
UT Southwestern Medical Center plastic surgeons and specialists in diabetes, neurology, pain management and rehabilitation are launching a cutting-edge study of peripheral nerve surgery to alleviate long-standing pain and numbness in patients with diabetic neuropathy. (2008-07-10)

Probiotic helps treat diabetes in rats, could lead to human remedy
Science may be one step closer to treating diabetes with a human probiotic pill, according to new Cornell University research. The researchers engineered a strain of lactobacillus, a human probiotic common in the gut, to secrete a Glucagon-like peptide 1. They then administered it orally to diabetic rats for 90 days and found the rats receiving the engineered probiotic had up to 30 percent lower high blood glucose, a hallmark of diabetes. (2015-01-29)

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