Popular Gastroenterology News and Current Events | Page 25

Popular Gastroenterology News and Current Events, Gastroenterology News Articles.
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New studies highlight the importance of bowel prep and effectiveness of colonoscopy
New research presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando emphasizes the importance of adequate bowel preparation prior to colonoscopy, and highlights the remarkable effectiveness of colonoscopy in detecting and removing pre-cancerous polyps, particularly tiny, flat, potentially pre-cancerous growths in the colon known as (2008-10-06)

Poor colonoscopy prep hides pre-cancerous polyps
What happens on the day before a colonoscopy may be just as important as the colon-screening test itself. Gastroenterologists at Washington University School of Medicine in St. Louis have found that when patients don't adequately prep for the test by cleansing their colons, doctors often can't see potentially dangerous pre-cancerous lesions. (2012-03-27)

Muscle cell infusion shown to strengthen sphincters in animals in Stanford study
A new study shows that muscle cells grown in the lab can restore an intestine's ability to squeeze shut properly. The work, performed in dogs and rats, might ultimately help treat patients with conditions such as gastric reflux and fecal incontinence. (2009-12-04)

Exercise improves symptoms in irritable bowel syndrome
Physical activity improves symptoms in patients with IBS and is protective against symptom deterioration. This has recently been shown in a study from the University of Gothenburg, Sweden. (2011-01-25)

Elastography: A useful method in depicting liver hardness
Elasticity measurements have been reported to be useful for the diagnosis and differentiation of many tumors, which are usually harder than normal surrounding tissues. Recently, trans-abdominal real-time elastography was proposed as a new method for noninvasive staging of liver fibrosis. A recently study from Romania found that computer-enhanced dynamic analysis of elastography movies is better able to characterize and differentiate between different degrees of liver fibrosis. (2010-04-12)

What is the life cycle of salmonella enteritidis like in the internal organs?
Salmonella enteritidis is one of the main causes of food-borne illness worldwide. In severe cases, it can reach the circulatory system. Knowledge about the distribution in the internal organs may lead to new insights into prevention and therapy. A research group led by Dr. Cheng has provided significant data for understanding the life cycle of Salmonella. enteritidis in the internal organs in normal mice after oral challenge. (2008-03-18)

What is sign for progressive of colorectal carcinoma?
The process of tumor invasion and metastasis is associated with alterations in the functions of several adhesion molecules. Reduced alpha-catenin expression was associated with tumor invasion and metastases in colorectal cancer. A group from University of Turku in Finland examined alpha-catenin expression in a series of 91 patients with advanced colorectal carcinoma, and analyzed the relationship with clinical and pathological features of CRC patients. (2008-09-19)

A rare case: Post-endoscopic retrograde cholangiopancreatography pneumoperitoneum
A team led by Dr. Stelios F. Assimakopoulos has reported an extremely rare case of post-ERCP pneumoperitoneum caused by rupture of intrahepatic bile ducts and Glisson's capsule in the area of a large peripheral hepatic metastasis. (2008-05-14)

Anti-HAV antibodies in beta-thalassemia
A team led by Dr. Chryssoula Labropoulou-Karatza and Dr. Dimitrios Siagris from the University of Patras detected that multi-transfused adult beta-thalassemia patients present a higher frequency of anti-Hepatitis A virus IgG antibodies than the normal population from the same geographic area. (2008-04-30)

Novel genes found in inflammatory bowel disease under Age 5
Researchers analyzing the complicated genetic influences in inflammatory bowel disease have discovered new gene variants associated with an often-severe type of the disease that affects children under age five. The genes play important roles in immune function, and that knowledge helps guide more precise, individualized treatments for very young patients. (2015-09-03)

A novel use of Nigella sativa on hepatic ischemia-reperfusion injury
Hepatic ischemia-reperfusion injury may occur in variety of clinical settings such as trauma, hepatic pedicle clamping during a liver surgery or liver transplantation. Several attempts have been reported to reduce the hepatic ischemia reperfusion injury. A research group in Turkey investigated whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. The results suggest that Nigella sativa treatment protects the rat liver against to hepatic ischemia-reperfusion injury. (2008-09-19)

Study shows ulcerative colitis patients achieve remission with probiotic composition VSL#3
Researchers reported study results today that demonstrated treatment with the highly concentrated probiotic preparation, VSL#3(TM), achieved a combined induced remission and/or response rate of 86 percent in patients with active mild to moderate ulcerative colitis who were not responding to conventional therapy. (2003-05-19)

The prevalence of hepatitis B virus infection in inflammatory bowel disease patients
Inflammatory Bowel Disease patients have a high risk of acquire the hepatitis B virus infection because they sometimes need blood transfusions, invasive surgical and endoscopic procedures. A research group from Gastroenterology Unit of Clementino Fraga Filho evaluated the prevalence of HBV infection in IBD patients and try to identify the possible risk factors involved in this infection transmission. (2008-09-18)

Losing sleep over heartburn? Treating nighttime heartburn improves sleep and boosts quality of life
The first major multi-center, randomized, double-blind, placebo-controlled trial addressing therapy for gastroesophageal reflux disease (GERD) related sleep disorders is published in the September issue of The American Journal of Gastroenterology. (2005-09-01)

AGA supports scientists' plea for national movement on the microbiome
AGA applauds the call for a formal approach to understanding microbial communities critical to all ecosystems, particularly the human body. (2015-11-02)

Strides in identifying and improving screening practices and treatment for liver diseases
Research being presented at Digestive Disease Week shows that screening individuals for hepatitis C based on age instead of conventional risk factors may help increase detection rates as well as prevent liver disease. Additionally, the rate of vaccination against viral hepatitis in patients with chronic liver disease and Type 2 diabetes is relatively low, and these patients are at increased risk of severe liver injury once infected. (2011-05-08)

How to save cost for esophageal varices?
Dr. Zaigham Abbas and his colleagues from the Aga Khan University, Karachi, Pakistan, have demonstrated that in patients undergoing eradication of esophageal varices, instead of using a new multiband ligator for each session, reloading the ligator for the follow-up sessions is a cost effective procedure and may be recommended for developing countries. (2008-05-20)

New study shows impact of birth order on maternal solicitousness towards children's GI symptoms
New research presented at the 70th Annual Scientific Meeting of the American College of Gastroenterology suggests that birth order impacts child perceptions of maternal solicitousness toward GI symptoms, particularly in families where the mother has Irritable Bowel Syndrome (IBS). (2005-10-31)

Enzyme inhibitor may provide strategy to treat some GI disorders, Jefferson researchers find
Researchers have known that the enzyme Rho kinase (ROK) plays an important role in maintaining the tone of the internal anal sphincter (IAS), which is crucial for normal bowel functioning. When the IAS tone is too high, drugs that block ROK activity might hold a key to treating resulting chronic and severe disorders such as certain forms of constipation, hemorrhoids, anal fissures, Hirschsprung's disease and other similar gastrointestinal problems. (2006-07-18)

Is the metastatic lymph node ratio can predict the survival rate in gastric cancer patients?
The metastatic lymph node ratio is defined as the ratio of the number of metastatic lymph nodes over the total number of resected lymph nodes. A research group in China investigated the prognostic impact of MLR on advanced gastric cancer from the cardia and fundus. They found that MLR can reflect the extent and the efficiency of lymphadenectomy for advanced gastric cancer. (2008-09-23)

New treatment offers hope for short-bowel syndrome patients
A new drug, teduglutide, offers significant relief for patients with short-bowel syndrome intestinal failure who are reliant on intravenous nutrition, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. (2013-07-18)

Marijuana use may cause severe cyclic nausea, vomiting, a little-known, but costly effect
Marijuana use -- both natural and synthetic -- may cause cannabinoid hyperemesis a little-known but costly effect that researchers suggest is a serious burden to the health care system as it often leads to expensive diagnostic tests and ineffective treatments in an effort to find the cause of a patient's symptoms and provide relief, according to two separate case reports unveiled today at the American College of Gastroenterology's 77th Annual Scientific meeting in Las Vegas. (2012-10-22)

Examining risks and benefits of alcohol consumption
A discussion by renowned epidemiologist Kenneth Mukamal has recently been published in the Journal of the American Medical Association, JAMA. It provides a discussion in response to a theoretical question: If you are a 42-year-old male, should you drink alcohol (in moderation) for your health? (2010-06-29)

Travel of a mis-swallowed long spoon to the jejunum
Foreign-body ingestion is a relatively common presentation at emergency departments, but long metallic spoon swallowing is an infrequent occurrence. Research led by Professor Jianyong Wu from China reported a case of a coffee spoon that was swallowed accidentally and passed through the pylorus and duodenal loop and reached the jejunum, with no complications. (2009-10-28)

What is the risk factor for gastric cancer in a Costa Rican?
A research group from Costa Rican evaluated risk factors for gastric cancer in Costa Rican regions with contrasting gastric cancer incidence rates (GCIR). They found that although a pro-inflammatory cytokine genetic profile showed an increased risk for developing gastric cancer (GC), the characteristics of Helicobacter pylori (H. pylori) infection, in particular the status of cagA and vacA genotype distribution seemed to play a major role in GCIR variability in Costa Rica. (2009-01-18)

Henry Ford study: Drug used for neuropathic pain relieves discomfort from abdominal adhesions
Pregabalin, FDA-approved for neuropathic pain (pain caused by shingles and peripheral neuropathy), effectively reduced abdominal pain and improved sleep in women with adhesions, according to a Henry Ford study. Adhesion pain, a common complication after abdominal or pelvic surgery, currently lacks effective therapy. Adhesions can also form after infections in the bowel such as diverticulitis. (2009-10-26)

Is endotoxin receptor CD14 rs2569190/C-159T gene correlated with chronic hepatitis C?
The variant allele T within the endotoxin receptor CD14 gene, rs2569190/C-159T was found to be associated with progressive alcoholic-related fibrosis. A research group in Germany investigated the correlation between this variation and liver disease manifestations in 2 different cohorts of chronic hepatitis C patients. The findings revealed that the T allele is more frequent in patients with portal lymphoid aggregates, but not in those with more advanced stages of fibrosis. (2009-08-26)

To what extent can environmental pollutants and alcohol affect GI health?
New research quantifies the precise effects of environmental pollutants and alcohol intake on gastrointestinal (GI) health. Both studies being presented this week during Digestive Disease Week 2009 offer concrete evidence that the environment and alcohol intake can affect GI health and share important insights into new directions for future research. (2009-05-31)

ASGE recognizes 48 endoscopy units for quality as part of its Endoscopy Unit Recognition Program
The American Society for Gastrointestinal Endoscopy has recognized 48 endoscopy units as part of its program specifically dedicated to promoting quality in endoscopy, in all settings where it is practiced in the United States. The ASGE Endoscopy Unit Recognition Program honors endoscopy units that follow the ASGE guidelines on privileging, quality assurance, endoscopy reprocessing and CDC infection control guidelines. To date, 215 endoscopy units have been recognized by ASGE. (2010-06-14)

A feasible and safe treatment for recurrent hepatocellular carcinoma in elderly patients
A research team from Hong Kong reported a case of repeated laparoscopic hepatectomy treating hepatocellular carcinoma (HCC) and its recurrence in an aged patient having cirrhosis, a disease causing extra difficulty for performing laparoscopic hepatectomy. This case report illustrates that laparoscopic hepatectomy for HCC is a good alternative to open hepatectomy because it has advantages including causing less adhesion after surgery, which renders re-operation much easier in cases of recurrence. (2010-02-04)

Targeting nerve growth factor may cure liver cancer
Biologists led by Dr. Serafino from the National Research Council of Italy published their surprising discovery that NGF and its receptor were aberrantly expressed in the liver of the patients troubled with liver cirrhosis and/or hepatocellular carcinoma (HCC). These two molecules are not expressed in the liver of healthy people. Published in the October 7 issue of the World Journal of gastroenterology, this article brings a bright future for devising a cure for HCC. (2007-09-05)

Cathepsin B increases apoptosis in fulminant hepatic failure
Recent evidence suggests that cathepsin B contributes to cell apoptosis. A research group in China investigated that LPS/D-Gal N-mediated cathepsin B expression initiates hepatocyte apoptosis in fulminant hepatic failure. Cathepsin B has an essential role in the pathogenesis of fulminant hepatic failure, and the cathepsin B inhibitor CA-074me could attenuate apoptosis and liver injury. (2009-03-20)

Is transforming growth factor-beta involved in intestinal wound healing?
A research group from Germany investigated the effects of transforming growth factor-beta (TGF-beta) on the differentiation of colonic lamina propria fibroblasts (CLPF) into myofibroblasts in vitro. They found that TGF-beta 1 potently stimulates the production of alpha-smooth muscle actin (alpha-SMA) in CLPF and therefore their differentiation into myofibroblasts as a result of long-term contact. (2009-03-30)

How to evaluate hemodynamics of gastric varices effectively?
A research team from China investigated the afferent and efferent veins of different types of gastric varices (GV) according to their location, with multidetector computed tomography portal venography (MDCTPV). Their results indicated that MDCTPV could display the collateral circulation of GV. It could provide a valuable reference for the treatment of GV bleeding. (2010-03-04)

Hepatitis transmission risk needs to be studied in nail salons, barbershops
The risk of hepatitis transmission through non-single use instruments -- such as nail files, nail brushes, finger bowls, foot basins, buffers, razors, clippers, and scissors -- during nail salon and barbershop visits cannot be excluded, according to the results of a new report unveiled today. (2011-10-31)

UNC research highlights at 2011 Digestive Disease Week
Below are a selection of oral presentations given at this year's Digestive Disease Week by University of North Carolina at Chapel Hill School of Medicine researchers. (2011-05-09)

Gastroenterologist-directed sedation safe and effective for endoscopic procedures
The use of an evidence-based sedation protocol for endoscopic procedures improves the quality of practice and reduces the incidence of sedation-related adverse events, according to an (2007-08-02)

Chronic hepatitis C infection in a patient with bone marrow hypoplasia
Cronic hepatitis C virus infection is associated with multifarious extra-hepatic manifestations; the most described and discussed being mixed cryoglobulinemia which is strongly associated to B-cell lymphoproliferative disorders. A research group from Centre Hospitalier Universitaire de Liege reported a case of chronic HCV infection with bone marrow hypoplasia in a patient. (2008-09-23)

DDW® 2015 offers reporters access to leading researchers in digestive health
DDW, May 16-19 in Washington, D.C., is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. The meeting showcases more than 6,000 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. DDW offers unique opportunities to connect with some of the world's leading GI researchers and attend press conferences highlighting key issues in consumer and medical news. (2015-03-16)

A new alternative in treating short bowel syndrome
Short bowel syndrome is a clinical condition characterized by diarrhea, dehydration, electrolyte imbalance, malabsorption, and progressive malnutrition related to a wide resection of the small intestine. Chlorella is a species of green algae that grows in fresh water. In this study the authors evaluated the efficacy of chlorella extract which has rich amino acids, beta carotene, and trace elements on the intestinal adaptation at the SBS. (2008-10-10)

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