Popular Gemcitabine News and Current Events | Page 6

Popular Gemcitabine News and Current Events, Gemcitabine News Articles.
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Metformin treatment caused cancer stem cell death in pancreatic cancer cell lines
Results of some preclinical trials have shown that low doses of the antidiabetic drug metformin may effectively destroy cancer stem cells, a group of cells that are considered to be responsible for tumor initiation and, because they are resistant to standard chemotherapies, tumor relapse. (2012-06-19)

Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. (2009-09-24)

New treatment combination safe for pancreatic cancer patients
Treating pancreatic cancer with a combination of chemotherapy, biotherapy and radiotherapy prior to surgery is safe and may be beneficial for patients, according to a University of Pittsburgh Cancer Institute study presented at the 44th annual meeting of the American Society of Clinical Oncology. In a preliminary study, physicians from the University of Pittsburgh Medical Center Cancer Centers examined the safety of combining gemcitabine with bevacizumab and radiotherapy in patients with operable pancreatic cancer. (2008-06-02)

Gene therapy improves gemcitabine effects in experimental glioma model
Attempts to improve the chemotherapeutic efficacy and radiotherapy-sensitivity of the anticancer agent, gemcitabine, using gene therapy have yielded interesting results in preclinical glioma models presented at the 13th European Cancer Conference (ECCO). (2005-10-31)

Erlotinib nearly triples progression-free survival compared with standard chemotherapy in patients with the most common form of lung cancer (OPTIMAL trial)
The targeted drug erlotinib nearly triples progression-free survival, and is better tolerated, compared with standard chemotherapy as the initial treatment for patients with advanced non-small-cell lung cancer whose tumors harbor epidermal growth factor receptor mutations. (2011-07-21)

Jefferson researchers identify critical marker of response to gemcitabine in pancreatic cancer
A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a priority report in Cancer Research, published by researchers at Thomas Jefferson University. (2009-06-04)

Pancreatic cancer patient survival 'significantly higher' with nab-paclitaxel, says TGen-led study
By all measures, the addition of nab-paclitaxel for the treatment of patients with advanced pancreatic cancer was superior to the survival for patients who received only gemcitabine, according to the results of a study led by the Translational Genomics Research Institute and Scottsdale Healthcare, published today by The New England Journal of Medicine. (2013-10-16)

Gene assay to help to predict lung cancer treatment resistance
The genes that may contribute to drug resistance in non-small cell lung cancer can be predicted. Researchers writing in the open access journal BMC Cancer found good correlation between genes believed to be involved in drug sensitivity and resistance and actual in vitro chemosensitivity. (2009-08-26)

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