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Popular Infectious Diseases News and Current Events, Infectious Diseases News Articles.
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University of Miami to begin phase 2 Zika vaccine trial
The University of Miami Miller School of Medicine will soon begin one of the nation's first full-scale Zika vaccine clinical trials testing the National Institutes of Health's (NIH) experimental DNA-based vaccine. As Miami-Dade County has been ground zero for the Zika virus outbreak in the U.S., testing the vaccine in an endemic region is critical to help determine the vaccine's safety, effective dosage and whether it can effectively prevent disease caused by Zika infection. (2017-03-31)

Experts release US policy roadmap to reduce antibiotics used in food animals
Leading physicians, veterinarians and other experts outline key steps for policymakers, food companies and food purchasers, and medical groups to help tackle the antibiotic resistance crisis. (2017-08-29)

Second HIV test helps prevent incorrect HIV diagnosis in infants
Confirmatory HIV testing can substantially reduce the number of infants in South Africa who may be falsely diagnosed as HIV-infected and started on unneeded treatment, according to a new study published this week in PLOS Medicine by Lorna Dunning of the University of Cape Town, South Africa, and colleagues. Confirmatory testing is recommended by the World Health Organization and South African guidelines, but in many settings, uptake is low. (2017-11-21)

Rapid development in Central Africa increases the risk of infectious disease outbreaks
The Central Africa region is experiencing rapid urbanization, economic growth and infrastructure development. These changes, while generally positive, also make the region more vulnerable to infectious disease outbreaks. Efforts to build up the health care infrastructure in Central Africa are critically needed to mitigate or prevent a large outbreak of Ebola or other infectious disease in the region. The authors represent 12 different organizations, including the National Institute of Allergy and Infectious Diseases. (2018-08-22)

HPTN 075 study demonstrates high rate of HIV infection among African MSM and TGW
HPTN 075 study demonstrates high rate of HIV infection among African men who have sex with men and transgender women. The incidence among study participants was substantially higher than the estimated incidence among heterosexual men and women in the general population in the same countries. (2018-10-24)

Understanding why virus can't replicate in human cells could improve vaccines
The identification of a gene that helps to restrict the host range of the modified vaccinia virus Ankara (MVA) could lead to the development of new and improved vaccines against diverse infectious agents, according to a study published May 30, 2019 in the open-access journal PLOS Pathogens by Bernard Moss of the National Institutes of Health, and colleagues. (2019-05-30)

Launch of the Lancet Asia Medical Forum
Some 500 scientists, public-health experts, and policy makers will be convening at the inaugural Lancet Asia Medical Forum on pandemic influenza in Singapore tomorrow. (2006-05-02)

New highways carry pathogens and social change in Ecuador
Logging roads have brought a higher incidence of diarrheal disease and new social problems among communities along the Ecuadorian coast, according to a new study by an international research team led by Joseph Eisenberg, assistant professor of epidemiology at the University of Michigan School of Public Health. (2006-12-04)

How a ubiquitous herpesvirus sometimes leads to cancer
Most of us are infected with the herpesvirus known as Epstein-Barr virus. For most of us, the virus will lead at worst to a case of infectious mononucleosis, but sometimes, and especially in some parts of the world, those viruses are found in association with cancer. Now, researchers have found that the difference between a relatively harmless infection and a cancer-causing one lies at least partly in the viral strain itself. (2013-10-10)

Measles outbreak underscores need for continued vigilance in health care settings
In 2008, the largest reported health care-associated measles outbreak in the United States since 1989 occurred in Tucson, Ariz., costing approximately $800,000 in response and containment efforts. In a report published in The Journal of Infectious Diseases and now available online, researchers identify preventive measures hospitals and health care facilities can implement to reduce the likelihood and decrease the economic impact of a future measles outbreak in these settings. (2011-04-29)

Endangered chimpanzees focus of urgent action
Endangered with imminent extinction, Africa's western chimpanzee is the focus of an urgent action plan to be announced Sept. 13 by an international group of scientists and government officials meeting in Abidjan. The plan will be finalized during a two-day conference at the Golf Hotel, Sept 12 and 13, with chimp conservation experts from Africa, the United States, Great Britain, Germany, Japan, France, the Netherlands, Italy and Portugal. (2002-09-04)

Sexually transmitted diseases, malaria, and tuberculosis and the HIV-1/AIDS epidemic in Africa
The effect of HIV-1 on other infectious diseases in Africa is an increasing public health concern. In a review in this week's issue of THE LANCET, Elizabeth Corbett from the London School of Hygiene and Tropical Medicine, UK, and the Harare Biomedical Research and Training Institute, Zimbabwe, and colleagues describe the role that three major infectious diseases-malaria, sexually transmitted diseases (STDs), and tuberculosis-have had in the HIV-1 epidemic. (2002-06-20)

Depression often co-occurs with joint diseases
Those suffering from depressive symptoms have an increased risk for physical diseases, especially for arthrosis and arthritis. These findings were reported by researchers from the University of Basel and the Ruhr-University Bochum. Their results, based on data from 14,300 people living in Switzerland, have been published in the scientific journal Frontiers in Public Health. (2015-04-01)

In a bad flu season, high-dose flu vaccine appeared better at preventing deaths in seniors
Older adults are at high risk for serious complications from flu and account for a majority of flu-related deaths and hospitalizations. H3N2 influenza viruses typically hit this age group particularly hard and have been associated with higher mortality than infections by H1N1 or influenza B viruses. During the 2012-2013 season, when H3N2 viruses were dominant, high-dose flu vaccine was 36 percent more effective at preventing deaths in the Medicare beneficiaries studied, compared to standard-dose vaccine. (2017-03-02)

Cleaner water through nanotechnology
Tiny particles of pure silica coated with an active material could be used to remove toxic chemicals, bacteria, viruses, and other hazardous materials from water much more effectively and at lower cost than conventional water purification methods, according to researchers writing in the current issue of Inderscience's International Journal of Nanotechnology. (2008-02-20)

Booster vaccination may help with possible future avian influenza pandemic
New evidence suggests that a booster vaccination against H5N1 avian influenza given years after initial vaccination with a different strain may prove useful in controlling a potential future pandemic. The study is published in the Aug. 1 issue of the Journal of Infectious Diseases, now available online. (2008-07-16)

Why is this year's flu so severe?
Why is this year's flu packing such a wallop? And why is it taking such a harsh toll on young children? Flu expert John Treanor, M.D., at the University of Rochester provides an update on this year's flu - and explains the reasons for its unusual severity - in the January 15, 2004 issue of the New England Journal of Medicine. (2004-01-14)

Hospitalizations for heart infection related to drug injection rising across the US
Hospitalizations for infective endocarditis, a heart valve infection often attributed to injection drug use, increased significantly among young adults, particularly whites and females. The findings shed light on the healthcare burdens and shifting demographics associated national opioid epidemic. (2016-09-01)

NIH advances understanding of defenses against antibiotic-resistant klebsiella bacteria
Klebsiella bacteria cause about 10 percent of all hospital-acquired infections in the United States. K. pneumoniae sequence type 258 (ST258) is one of the Carbapenem-Resistant Enterobacteriaceae organisms labeled an urgent threat by the Centers for Disease Control and Prevention. This strain of bacteria is particularly concerning because it is resistant to most antibiotics and kills nearly half of people with bloodstream infections. (2017-01-25)

'Genetic scalpel' can manipulate the microbiome, Yale study shows
Yale University researchers have developed new methods for regulating gene activity in a widespread group of microbiome bacteria in the gut of living mice -- a crucial step in understanding microbiome's impact on health and disease. (2017-04-20)

DNA-based Zika vaccine is safe and effective at inducing immune response
A new generation DNA-based Zika vaccine demonstrated both safety and ability to elicit an immune response against Zika in humans in a phase 1 clinical trial conducted through a partnership among the Perelman School of Medicine at the University of Pennsylvania, Inovio Pharmaceuticals, GeneOne Life Science, and The Wistar Institute. (2017-10-04)

Clear strategies needed to reduce bushmeat hunting
Extensive wildlife trade not only threatens species worldwide but can also lead to the transmission of zoonotic diseases. An international research team led by the Max Planck Institute for Evolutionary Anthropology and the German Centre for Integrative Biodiversity Research shed new light on the motivations why people hunt, trade or consume different species. The research shows that more differentiated solutions are needed to prevent uncontrolled disease emergence and species decline. (2020-07-17)

Wayne State receives $1.9 million NIH award to aid in treatment of life-threatening infections
Infections caused by vancomycin-resistant Enterococcus faecium (VREfm) bacteria can often be serious and life threatening. These drug-resistant bacterial pathogens are one of the most problematic in the hospital setting, especially in immune system deficient patients, and constitute an emerging local and global health crisis. Wayne State University recently received a five-year, $1.9 million grant from the the National Institutes of Health to further explore treatment of these problematic bacteria in the hospital setting. (2016-01-15)

Discovery in Nature elucidates immune cells in skin and supports novel vaccine approach
Research in Nature shows for the first time in vivo that powerful immune system cells called TREMs (T-Resident Effector Memory cells) prevalent in the skin are more protective in fighting infection than central memory T-cells in the bloodstream. The study suggests vaccines to generate TREM can have optimal delivery to upper skin, for potentially more effective immune response than conventional vaccine injection. TREM Rx is translating this new insight into proprietary platform for novel vaccines. (2012-02-29)

Study by Pittsburgh researchers identifies possible vaccine target for chlamydia
Scientists at Children's Hospital of Pittsburgh of UPMC have identified a potential target for the development of a vaccine against Chlamydia trachomatis, the most prevalent sexually transmitted bacterial infection in the world. (2007-09-12)

Researchers define burden of Hepatitis in Democratic Republic of the Congo
Using laboratory equipment readily available in developing countries, researchers from UNC and Abbott Diagnostics were able to define and map the burden of hepatitis C virus for the first time in the Democratic Republic of the Congo. Their findings were published in Clinical Infectious Diseases. (2017-10-18)

New Penn-developed vaccine prevents herpes in mice, guinea pigs
A novel vaccine developed at Penn Medicine protected almost all mice and guinea pigs exposed to the herpes virus. This may lead to the vaccine being tested in human studies. (2019-09-20)

Skin and mucous membrane lesions as complication of pneumonia
Painful inflammatory lesions of the skin and mucous membranes may occur in children who develop bacterial pneumonia. A research group at the University Children's Hospital Zurich has recently developed a new diagnostic blood test, which reliably diagnoses bacteria as the causative pathogen at an early stage, allowing more specific treatment and prediction about prognosis. (2019-12-19)

Compound kills highly contagious flu strain by activating antiviral protein
A compound tested by University of Texas Southwestern Medical Center investigators destroys several viruses, including the deadly Spanish flu that killed an estimated 30 million people in the worldwide pandemic of 1918. (2011-09-26)

Key goals for building on 30 years of HIV/AIDS research
In the 30 years since the first reported cases of a mysterious illness now known as AIDS, researchers have made extraordinary advances in understanding, treating and preventing the disease. Now the challenge, according to experts at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is to build on those successes to control and, ultimately, end the HIV/AIDS pandemic. (2011-05-31)

New Drug Shown Effective Against Vancomycin-Resistant Bacteria
Northwestern University Medical School researchers have successfully used a new drug, linezolid, in a patient with a severe bacterial infection that was resistant to all antibiotics, including vancomycin. (1999-03-09)

Good relationships with parents may benefit children's health decades later
Growing up in a well-off home can benefit a child's physical health even decades later -- but a lack of parent-child warmth, or the presence of abuse, may eliminate the health advantage of a privileged background, according to a Baylor University study. (2016-10-05)

Severe West Nile infection could lead to lifetime of symptoms
Most people who suffer severe infection with West Nile virus still experience symptoms years after infection and many may continue to experience these symptoms for the rest of their lives according to research presented today at the 2008 International Conference on Emerging Infectious Diseases. (2008-03-17)

NIAID scientists identify new cellular receptor for HIV
A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. (2008-02-10)

Can North American animals such as rabbits, cows, or pigs serve as hosts for Zika virus?
The mosquito-borne Zika virus might be able to infect and reproduce in a variety of common animal species, and a new study looked at 16 different types of animals, including goats, pigeons, raccoons, and ducks, to determine their potential to serve as hosts for Zika virus. (2017-02-21)

Funding for development of new strategies to treat and prevent hepatitis C virus
Current drug treatments for hepatitis C virus are prohibitively expensive and have limiting side effects and achieve sustained clearance of the virus in only 50-60 percent of patients. In a project funded by the Medical Research Council scientists from the Nuffield Department of Medicine at the University of Oxford and the School of Biomedical and Healthcare Sciences at the University of Plymouth take a new look at this problem by using a recently developed model system. (2017-01-13)

Measuring genomic response to infection leads to earlier, accurate diagnoses
Duke researchers are looking to genomic technologies -- not the isolation of bacteria or viruses -- to quickly detect and diagnose infectious diseases such as the flu and staph. (2013-01-09)

NIAID scientists develop 'mini-brain' model of human prion disease
Scientists have used human skin cells to create what they believe is the first cerebral organoid system, or 'mini-brain,' for studying sporadic Creutzfeldt-Jakob disease (CJD). CJD is a fatal neurodegenerative brain disease of humans believed to be caused by infectious prion protein. The researchers, from NIH's National Institute of Allergy and Infectious Diseases, hope the human organoid model will enable them to evaluate potential CJD therapeutics and provide greater detail about human prion disease subtypes. (2019-06-14)

How kissing as a risk factor may explain the high global incidence of gonorrhoea
In 2016, there were 87 million people diagnosed with gonorrhoea, the most antibiotic resistant of all the STIs. There is a global rise in gonorrhoea rates and, until now, no one has understood why. (2019-07-17)

Emerging infectious disease and challenges of social distancing in human and non-human animals
Humans are not the only social animal struggling with new infectious diseases. This review examines the behavioral responses to emerging diseases across the animal kingdom from frogs and wolves to lobsters, bats, and humans. The paper also addresses whether or not technology helps when it comes to dealing with humans and social distancing. (2020-08-12)

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