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Popular Leukemia News and Current Events

Popular Leukemia News and Current Events, Leukemia News Articles.
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Penn-developed approach could limit toxicity of CAR T therapy in acute myeloid leukemia
A new approach pioneered at the University of Pennsylvania's Abramson Cancer Center may provide a new path towards treating acute myeloid leukemia (AML) with CAR T cells. (2018-05-31)
Mutations in bone cells can drive leukemia in neighboring stem cells
DNA mutations in bone cells that support blood development can drive leukemia formation in nearby blood stem cells. (2016-10-26)
Combination therapy more effective than chemotherapy alone for many newly diagnosed leukemia patients
A Phase II study pairing azacitidine with enasidenib boosts complete remission in patients with AML with IDH2 mutations. (2019-12-09)
Russian chemists discovered a surprising effect of a well-known leukemia drug
Researchers from RUDN University and Institute of Biomedical Chemistry of the Russian Academy of Sciences have identified an alternative mechanism for the effective antitumor drug -- an enzyme called L-asparaginase. (2017-11-10)
Personalizing chemotherapy to treat pediatric leukemia
A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses. (2016-12-12)
U of M begins nation's first clinical trial using T-reg cells from cord blood in leukemia treatment
University of Minnesota researchers have initiated a ground breaking clinical trial to determine the optimal dose and safety of T regulatory cells (T-regs) to decrease the risk of immune reactions common in patients undergoing blood and marrow transplantation. (2007-09-05)
Ancient anti-inflammatory drug salicylic acid has cancer-fighting properties
Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid -- a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal -- stops inflammation and tumor growth in cancer. (2016-05-31)
Multifunctional protein contributes to blood cell development
Salk researchers uncover mechanism for how blood cells mature and specialize--and why errors can sometimes lead to leukemia. (2017-12-21)
Researchers identify compound to prevent breast cancer cells from activating in brain
Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain. (2018-03-22)
The HLF-gene controls the generation of our long-term immune system
A research group at Lund University in Sweden has found that when the HLF (hepatic leukemia factor) gene -- which is expressed in immature blood cells -- does not shut down on time, we are unable to develop a functional long-term immune system. (2017-11-22)
UCLA researchers identify leukemia stem cells
Stem cell researchers at UCLA have identified a type of leukemia stem cell and uncovered the molecular and genetic mechanisms that cause a normal blood stem cells to become cancerous. (2008-05-23)
An errant editing enzyme promotes tumor suppressor loss and leukemia propagation
UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation. (2019-01-03)
New CAR T case study shows promise in acute myeloid leukemia
According to a case study from trial published online ahead of print in the journal Haematologica, a patient has remained cancer free for nine months after being treated with CYAD-01, followed by a bone marrow transplant. (2018-05-09)
AML study reports high response rates with combination targeted therapy
Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center. (2017-12-11)
Dana-Farber/Boston Children's opens immunotherapy trial for children with leukemia
Dana-Farber/Boston Children's Cancer and Blood Disorders Center has joined a clinical trial of immunotherapy for children with relapsed or treatment-resistant acute lymphoblastic leukemia (ALL). (2015-05-11)
T cell therapy shows persistent benefits in young leukemia patients
Updated results from a global clinical trial of the CAR T-cell therapy, tisagenlecleucel, a landmark personalized treatment for a high-risk form of acute lymphoblastic leukemia (ALL), reveal that children and young adults continued to show high rates of durable, complete remission of their disease. (2018-01-31)
Immunotherapy combination and chemotherapy show encouraging results in Phase II acute myeloid leukemia study
A triple therapy combining two immune checkpoint inhibitors (ICPIs) with the standard-of-care chemotherapy, a hypomethylating agent called azacitidine, has shown promising results for treatment of relapsed or refractory acute myeloid leukemia (AML), according to findings from a Phase II study at The University of Texas MD Anderson Cancer Center. (2018-11-13)
Silencing a protein could kill T-Cells, reverse leukemia
Blocking the signals from a protein that activates cells in the immune system could help kill cells that cause a rare form of blood cancer, according to physicists and oncologists who combined computer modeling and molecular biology in their discovery. (2008-10-22)
Study provides new clues to leukemia resurgence after chemotherapy
For the first time, researchers have discovered that some leukemia cells harvest energy resources from normal cells during chemotherapy, helping the cancer cells not only to survive, but actually thrive, after treatment. (2016-06-02)
For leukemia patients, transfusion needs may delay hospice care
Researchers report that thousands of leukemia patients who received frequent transfusions had very short stays in hospice at the end of life, suggesting that transfusion dependence presents a barrier to making meaningful use of palliative care. (2017-12-09)
Without 'yoga and chardonnay' leukemia stem cells are stressed to death
University of Colorado Cancer Center researchers nix leukemia stem cell (LSC) stress-relief pathway to kill LSCs without harming healthy blood stem cells, paving the way for new therapies targeting these most dangerous cancer cells. (2018-06-14)
Neurocognitive risk may begin before treatment for young leukemia patients
Chemotherapy agents have been associated with neurocognitive side effects in young leukemia survivors. (2018-03-29)
Three of the most deadly cancers get critical funding for research
Three of the most deadly cancers -- glioblastoma, sarcoma and ovarian -- get critical funding for clinical trials from Alliance for Cancer Gene Therapy. (2017-10-17)
Discovery adds to evidence that some children are predisposed to develop leukemia
St. Jude Children's Research Hospital scientists have discovered a fourth gene that can predispose carriers to the most common childhood cancer, expanding the list of genes to include in cancer screening. (2018-04-19)
Research shows cord blood comparable to matched bone marrow
University of Minnesota researchers report that umbilical cord blood transplants may offer blood cancer patients better outcomes than bone marrow transplants, according to an analysis of outcome data performed at the Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee. (2007-06-07)
New insights into treating a rare leukemia
Patients with MPAL initially treated with ALL therapy -- a significantly less-toxic regimen -- were three to five times more likely to achieve a complete remission than AML-treated patients. (2018-02-27)
Novel pathway identified in development of acute myeloid leukemia with poor prognosis
NUS researchers have discovered a new pathway by which a severe form of acute myeloid leukemia (AML) develops. (2018-04-24)
Researchers detect a loophole in chronic lymphocytic leukemia treatment
A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients. (2018-01-04)
Potential seen for tailoring treatment for acute myeloid leukemia
Rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia. (2018-12-07)
Daisies lead scientists down path to new leukemia drug
A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood. (2007-10-02)
Chemo-boosting drug discovered for leukemia
Drugs developed to treat heart and blood vessel problems could be used in combination with chemotherapy to treat an aggressive form of adult leukemia, new research led by the Francis Crick Institute reveals. (2017-08-31)
Melatonin may help treat blood cancers
Researchers have examined the potential benefits of melatonin, a hormone made by a small gland in the brain, for treating blood cancers such as leukemia and lymphoma. (2017-09-01)
Throwing molecular wrench into gene control machine leads to 'melting away' of leukemia
Researchers have figured out a way to prevent MYB, one of the most potent cancer-aiding proteins, from activating genes in AML, an aggressive form of leukemia. (2018-01-08)
Survey points out need for education for primary care physicians on rarely seen cancers
Many primary care physicians may lack the necessary knowledge when it comes to recognizing the signs, symptoms and making proper diagnoses in cases of blood cancers such as leukemia and lymphoma, a recent survey indicates. (2007-12-10)
A new Achilles' heel of blood cancer
Acute Myeloid Leukemia is an aggressive form of blood cancer. (2018-05-18)
Pediatric leukemia 'super drug' could be developed in the coming years
Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the final paper published Dec. (2018-12-21)
New leukemia treatment outperforms standard chemotherapies
Researchers at The Australian National University (ANU) are working on a new treatment for an aggressive type of leukemia that outperforms standard chemotherapies. (2017-06-08)
Study reveals key inner control mechanism of cell's 'smart glue'
Understanding of ALS and acute myeloid leukemia could advance with discovery of how the protein nucleophosmin undergoes 'self-interaction,' a St. (2018-02-26)
CRISPR-based system identifies important new drug targets in a deadly leukemia
Scientists have harnessed CRISPR, the gene-editing tool, to find highly specific dependencies in a deadly subtype of leukemia. (2018-03-08)
Study of tagraxofusp reports 90% response rate for deadly blood cancer with no prior available therapies
An open-label, multi-cohort Phase II trial, led by investigators at the University of Texas MD Anderson Cancer Center, reports that treatment with the drug tagraxofusp resulted in high response rates in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare but highly aggressive -- and often fatal bone marrow and blood disorder -- for which there are no existing approved therapies. (2019-04-24)
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