Popular Lung Function News and Current Events

Popular Lung Function News and Current Events, Lung Function News Articles.
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Patients with Stage IV squamous non-small cell lung cancer enrolled in clinical trial to test the immunotherapy atezolizumab and chemotherapy against chemotherapy alone experienced a longer survival rate, among a subgroup of patients with high PD-LI. (2019-09-10)

How reducing body temperature could help a tenth of all ICU patients
ROCKVILLE, MD - A tenth of all intensive care unit patients worldwide, and many critical patients with COVID-19, have acute respiratory distress syndrome (ARDS). (2021-02-23)

Innate immune system worsens the situation in severe COVID-19
In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients. This is shown in an Uppsala University study published in the journal Frontiers in Immunology. (2021-02-23)

Scientists identify potential contributor to hyper immune responses in patients with severe COVID-19
Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease (2021-02-23)

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified. The goal is to develop an over-the-counter screening product, similar to a pregnancy test, in terms of cost, simplicity and availability. Dr. Quinn envisions a device that someone can breathe into and see a color change to indicate a positive or negative finding. (2019-06-17)

Radiotherapy for invasive breast cancer increases the risk of second primary lung cancer
East Asian female breast cancer patients receiving radiotherapy have a higher risk of developing second primary lung cancer. (2017-02-15)

PETA science group promotes animal-free science at society of toxicology conference
The PETA International Science Consortium Ltd. is presenting two posters on animal-free methods for testing inhalation toxicity at the 56th annual Society of Toxicology (SOT) meeting March 12 to 16, 2017, in Baltimore, Maryland. This meeting is the largest international conference of its kind, drawing approximately 7,000 scientists from more than 50 countries each year. (2017-03-16)

Smoking and mortality in Asia
In this analysis of data from 20 studies conducted in China, Japan, South Korea, Singapore, Taiwan and India with more than 1 million participants, deaths associated with smoking continued to increase among men in Asia grouped by the years in which they were born. Among the study participants, there were 144,366 deaths (with 9,158 from lung cancer) during an average follow-up of almost 12 years. (2019-03-29)

Radiotherapy for lung cancer patients is linked to increased risk of non-cancer deaths
Researchers have found that treating patients who have early stage non-small cell lung cancer with a type of radiotherapy called stereotactic body radiation therapy is associated with a small but increased risk of death from causes other than cancer. The findings are presented at the annual meeting of the European Society for Radiotherapy and Oncology - ESTRO35. (2016-05-01)

Fitness in childhood linked to healthy lungs in adulthood
Children who are fitter and whose fitness improves during childhood and adolescence have better lung function as young adults, according to a large study published in the European Respiratory Journal. (2018-01-31)

The Lancet: 3-in-1 inhaler therapy can improve lung function and reduce asthma attacks
Patients with severe asthma which is not controlled with standard treatment -- leaving them at risk of severe asthma attacks -- could benefit from using a single inhaler combining three, instead of 2 therapies, according to two phase 3 randomized controlled trials with over 2,500 patients across 17 countries, published in The Lancet and simultaneously presented at the European Respiratory Society (ERS) Conference 2019. (2019-09-30)

Study uncovers healthcare disparities among octogenarians and nonagenarians with advanced lung cancer
A new study reveals that, among patients of advanced age with stage III lung cancer, African Americans and individuals who live in lower income areas are more likely to not receive any treatment. (2018-01-08)

Lung transplant patients face elevated lung cancer risk
In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients. (2018-12-19)

The Lancet journals: Papers at ERS Congress 2019
The following papers will be presented at the ERS Congress 2019, organised by the European Respiratory Society, in Madrid and published simultaneously in either The Lancet or The Lancet Respiratory Medicine journals. All papers are under embargo until the stated time. Contact details for corresponding authors are provided in the Articles and linked Comments. Funding information is listed on the first page of each Article. (2019-09-30)

New research finds novel method for generating airway cells from stem cells
Researchers have developed a new approach for growing and studying cells they hope one day will lead to curing lung diseases such as cystic fibrosis through 'personalized medicine.' (2017-03-30)

Free lung-cancer screening in the Augusta area finds more than double the cancer rate of previous screenings
The first year of free lung cancer screening in the Augusta, Ga., area found more than double the rate seen in a previous large, national study as well as a Massachusetts-based screening for this No. 1 cancer killer. (2017-03-09)

Lung cancer may go undetected in kidney cancer patients
Could lung cancer be hiding in kidney cancer patients? Researchers with the Harold C. Simmons Comprehensive Cancer Center's Kidney Cancer Program studied patients with metastatic kidney cancer to the lungs and found that 3.5 percent of the group had a primary lung cancer tumor that had gone undiagnosed. This distinction can affect treatment choices and rates of survival. (2017-03-07)

Two studies explore gender, language, and treatment setting as barriers in screening and patient care in lung cancer
More people die of lung cancer than any other type of cancer, and two new studies from CHEST 2017 reveal disparities in lung cancer screening and care that may impact detection, as well as mortality and survival rates in the disease. (2017-10-23)

AI helps to fight against lung cancer
Lung cancer has been the leading cause of cancer-related deaths in 2015 in United States. Early detection of lung nodules will undoubtedly increase the five-year survival rate for lung cancer according to prior studies. In a paper published in SCIENCE CHINA Information Sciences, researchers propose a novel rating method based on geometrical and statistical features to extract initial nodule candidates and an artificial neural network approach to the detection of lung nodules. (2017-06-29)

Simple breathing training with a physiotherapist before surgery prevents postoperative pneumonia
Pneumonia, and other serious lung complications, after major abdominal surgery were halved when patients were seen by a physiotherapist before surgery and taught breathing exercises that the patient needed to start performing immediately on waking from the operation, finds a trial published by The BMJ today. (2018-01-24)

Airway-on-a-chip could lead to new treatments for cigarette smoke-induced lung injury
Researchers have developed an airway-on-a-chip that supports living small-airway-lining cells from normal or diseased human lungs and an instrument that 'breathes' cigarette smoke in and out over these chips. Using this technology, researchers from the Wyss Institute at Harvard University recreated and analyzed the effects of smoking at the molecular, cellular, and tissue level to understand the damage occurring in normal lung and in engineered lung tissues from patients with chronic obstructive pulmonary disease (COPD). (2016-10-27)

Two ADAURA analyses support use of Osimertinib for patients with surgically resected, Stage IB to IIIA non-small cell lung cancer
Two presentations from the ADAURA clinical trial advanced previous research that demonstrated improved disease-fee survival (DFS) outcomes for patients with surgically resected non-small cell lung cancer (NSCLC) receiving osimertinib. The data were reported today at the International Association for the Study of Lung Cancer's 2020 World Conference on Lung Cancer (WCLC) Singapore. (2021-01-29)

High EGFR expression a predictor for improved survival with cetuximab plus chemotherapy
High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer. (2011-07-05)

Hitgen and Cancer Research UK's Manchester Institute enter license agreement in lung cancer
Cancer Research UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer. (2017-02-27)

Antioxidants and lung cancer risk
An epidemiological study published in Frontiers in Oncology suggests that a diet high in carotenoids and vitamin C may protect against lung cancer. The study authors found that vitamin C appears to reduce the risk of lung cancer in heavy smokers while beta-carotene, alpha-carotene, beta-cryptoxanthin, and lycopene play the same role in male heavy smokers. (2017-03-08)

From Genome Research: Pathogen demonstrates genome flexibility in cystic fibrosis
Chronic lung infections can be devastating for patients with cystic fibrosis (CF), and infection by Burkholderia cenocepacia, one of the most common species found in cystic fibrosis patients, is often antibiotic resistant. In a study published today in Genome Research, scientists sequenced and phenotyped multiple B. cenocepacia isolates from 16 CF patients. They found extensive variation among isolates during chronic lung infection as well as changes in clinically relevant bacterial phenotypes. (2017-03-21)

Academic performance of urban children with asthma worse than peers without asthma
A new study published in Annals of Allergy, Asthma and Immunology shows urban children with poorly controlled asthma, particularly those who are ethnic minorities, also suffer academically. Kids who were kept home due to asthma symptoms weren't able to do as well in the classroom. (2019-03-11)

TB tricks the body's immune system to allow it to spread
Tuberculosis tricks the immune system into attacking the body's lung tissue so the bacteria are allowed to spread to other people, new research from the University of Southampton suggests. (2016-10-20)

Lung cancer mortality rates among women projected to increase by over 40 percent by 2030
The global age-standardized lung cancer mortality rate among women is projected to increase by 43 percent from 2015 to 2030, according to an analysis of data from 52 countries. The global age-standardized breast cancer mortality rate is projected to decrease by 9 percent in the same time frame. (2018-08-01)

High levels of estrogen in lung tissue related to lung cancer in postmenopausal women
Researchers from Kumamoto University, Japan have found that postmenopausal women with multicentric adenocarcinoma of the lung have a higher concentration of estrogen in non-cancerous areas of the peripheral lung than similar women diagnosed with single tumor lung cancer. The research is an extension of their previous investigation into a gene mutation found to be related to an increased risk of multicentric lung cancer. (2016-10-25)

Pericardial window operation less efficient in cases of lung cancer than any other cancer
Pericardial window operation, a procedure, where abnormal quantity of malignant fluid, surrounding the heart, is drained into the neighbouring chest cavity, is commonly applied to patients diagnosed with cancer. Taiwanese specialists have now looked into the electronic medical records from a hospital and concluded that the treatment is not as effective in lung cancer cases when compared to any other cancer patients. Their research is published in the open access journal Research Ideas and Outcomes. (2016-04-11)

Huntsman Cancer Institute research holds promise for personalized lung cancer treatments
New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah uncovered distinct types of tumors within small cell lung cancer that look and act differently from one another. Scientists also identified a targeted drug combination that worked well with one specific tumor type. The study was published today in Cancer Cell. The findings suggest small cell lung cancer should not be treated as a uniform disease. (2017-01-12)

Regular exercise halves complication rate after lung cancer surgery
Exercising regularly before surgery for lung cancer halves the complication rate afterwards, finds a synthesis of the available published evidence in the British Journal of Sports Medicine. (2018-02-01)

Research leads to call for lung health screening at top football clubs
New research from the University of Kent has discovered that nearly three in 10 elite footballers at top clubs in England have undetected lung and airway problems that could impair their on-field performance. The findings of this study will be presented at a British Thoracic Society meeting on Dec. 8 by lead researcher Anna Jackson, who will also call for all top football clubs to implement a lung health screening program. (2017-12-08)

NIH researchers report first 3-D structure of DHHC enzymes
The first three-dimensional structure of DHHC proteins -- enzymes involved in many cellular processes, including cancer -- explains how they function and may offer a blueprint for designing therapeutic drugs. (2018-01-11)

Early-life events linked to lung health in young adulthood
Early-life events, such as the exposure to air pollutants, increases the risk of chronic lung disease in young adulthood, according to new results by researchers at Karolinska Institutet, Sweden, published in the European Respiratory Journal and Thorax. The studies add to the growing evidence that chronic lung disease in adulthood can be traced back to childhood. (2020-11-12)

Dartmouth study reveals how fungal biofilm structure impacts lung disease
Findings from an innovative new study led by researchers at Dartmouth's Geisel School of Medicine and published this week in Nature Microbiology reveal that the way in which human fungal pathogens form colonies can significantly impact their ability to cause disease. Understanding how these colonies form could lead to new therapies that target these infections in critically ill patients. (2019-09-23)

Blood test shows potential for early detection of lung cancer
A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests. (2018-06-02)

Childhood body composition may help determine future lung health
Boys and girls with more muscle mass in childhood and adolescence have higher lung function. (2019-01-11)

Alectinib provides longer symptom improvement than crizotinib in ALK-positive lung cancer
The findings of the ALEX trial presented at the ELCC (European Lung Cancer Congress) 2018 in Geneva, Switzerland, support the use of alectinib as the new standard of care in the frontline treatment of ALK-positive lung cancer. Alectinib was found to provide longer symptom improvement than crizotinib in ALK-positive non-small-cell lung cancer. (2018-04-12)

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