Popular Lung Function News and Current Events

Popular Lung Function News and Current Events, Lung Function News Articles.
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Patients with Stage IV squamous non-small cell lung cancer enrolled in clinical trial to test the immunotherapy atezolizumab and chemotherapy against chemotherapy alone experienced a longer survival rate, among a subgroup of patients with high PD-LI. (2019-09-10)

Radiotherapy for invasive breast cancer increases the risk of second primary lung cancer
East Asian female breast cancer patients receiving radiotherapy have a higher risk of developing second primary lung cancer. (2017-02-15)

The Lancet: 3-in-1 inhaler therapy can improve lung function and reduce asthma attacks
Patients with severe asthma which is not controlled with standard treatment -- leaving them at risk of severe asthma attacks -- could benefit from using a single inhaler combining three, instead of 2 therapies, according to two phase 3 randomized controlled trials with over 2,500 patients across 17 countries, published in The Lancet and simultaneously presented at the European Respiratory Society (ERS) Conference 2019. (2019-09-30)

Radiotherapy for lung cancer patients is linked to increased risk of non-cancer deaths
Researchers have found that treating patients who have early stage non-small cell lung cancer with a type of radiotherapy called stereotactic body radiation therapy is associated with a small but increased risk of death from causes other than cancer. The findings are presented at the annual meeting of the European Society for Radiotherapy and Oncology - ESTRO35. (2016-05-01)

Study uncovers healthcare disparities among octogenarians and nonagenarians with advanced lung cancer
A new study reveals that, among patients of advanced age with stage III lung cancer, African Americans and individuals who live in lower income areas are more likely to not receive any treatment. (2018-01-08)

The Lancet journals: Papers at ERS Congress 2019
The following papers will be presented at the ERS Congress 2019, organised by the European Respiratory Society, in Madrid and published simultaneously in either The Lancet or The Lancet Respiratory Medicine journals. All papers are under embargo until the stated time. Contact details for corresponding authors are provided in the Articles and linked Comments. Funding information is listed on the first page of each Article. (2019-09-30)

New research finds novel method for generating airway cells from stem cells
Researchers have developed a new approach for growing and studying cells they hope one day will lead to curing lung diseases such as cystic fibrosis through 'personalized medicine.' (2017-03-30)

Fitness in childhood linked to healthy lungs in adulthood
Children who are fitter and whose fitness improves during childhood and adolescence have better lung function as young adults, according to a large study published in the European Respiratory Journal. (2018-01-31)

Two studies explore gender, language, and treatment setting as barriers in screening and patient care in lung cancer
More people die of lung cancer than any other type of cancer, and two new studies from CHEST 2017 reveal disparities in lung cancer screening and care that may impact detection, as well as mortality and survival rates in the disease. (2017-10-23)

Lung cancer may go undetected in kidney cancer patients
Could lung cancer be hiding in kidney cancer patients? Researchers with the Harold C. Simmons Comprehensive Cancer Center's Kidney Cancer Program studied patients with metastatic kidney cancer to the lungs and found that 3.5 percent of the group had a primary lung cancer tumor that had gone undiagnosed. This distinction can affect treatment choices and rates of survival. (2017-03-07)

Airway-on-a-chip could lead to new treatments for cigarette smoke-induced lung injury
Researchers have developed an airway-on-a-chip that supports living small-airway-lining cells from normal or diseased human lungs and an instrument that 'breathes' cigarette smoke in and out over these chips. Using this technology, researchers from the Wyss Institute at Harvard University recreated and analyzed the effects of smoking at the molecular, cellular, and tissue level to understand the damage occurring in normal lung and in engineered lung tissues from patients with chronic obstructive pulmonary disease (COPD). (2016-10-27)

Simple breathing training with a physiotherapist before surgery prevents postoperative pneumonia
Pneumonia, and other serious lung complications, after major abdominal surgery were halved when patients were seen by a physiotherapist before surgery and taught breathing exercises that the patient needed to start performing immediately on waking from the operation, finds a trial published by The BMJ today. (2018-01-24)

AI helps to fight against lung cancer
Lung cancer has been the leading cause of cancer-related deaths in 2015 in United States. Early detection of lung nodules will undoubtedly increase the five-year survival rate for lung cancer according to prior studies. In a paper published in SCIENCE CHINA Information Sciences, researchers propose a novel rating method based on geometrical and statistical features to extract initial nodule candidates and an artificial neural network approach to the detection of lung nodules. (2017-06-29)

Free lung-cancer screening in the Augusta area finds more than double the cancer rate of previous screenings
The first year of free lung cancer screening in the Augusta, Ga., area found more than double the rate seen in a previous large, national study as well as a Massachusetts-based screening for this No. 1 cancer killer. (2017-03-09)

Antioxidants and lung cancer risk
An epidemiological study published in Frontiers in Oncology suggests that a diet high in carotenoids and vitamin C may protect against lung cancer. The study authors found that vitamin C appears to reduce the risk of lung cancer in heavy smokers while beta-carotene, alpha-carotene, beta-cryptoxanthin, and lycopene play the same role in male heavy smokers. (2017-03-08)

From Genome Research: Pathogen demonstrates genome flexibility in cystic fibrosis
Chronic lung infections can be devastating for patients with cystic fibrosis (CF), and infection by Burkholderia cenocepacia, one of the most common species found in cystic fibrosis patients, is often antibiotic resistant. In a study published today in Genome Research, scientists sequenced and phenotyped multiple B. cenocepacia isolates from 16 CF patients. They found extensive variation among isolates during chronic lung infection as well as changes in clinically relevant bacterial phenotypes. (2017-03-21)

Hitgen and Cancer Research UK's Manchester Institute enter license agreement in lung cancer
Cancer Research UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer. (2017-02-27)

TB tricks the body's immune system to allow it to spread
Tuberculosis tricks the immune system into attacking the body's lung tissue so the bacteria are allowed to spread to other people, new research from the University of Southampton suggests. (2016-10-20)

Pericardial window operation less efficient in cases of lung cancer than any other cancer
Pericardial window operation, a procedure, where abnormal quantity of malignant fluid, surrounding the heart, is drained into the neighbouring chest cavity, is commonly applied to patients diagnosed with cancer. Taiwanese specialists have now looked into the electronic medical records from a hospital and concluded that the treatment is not as effective in lung cancer cases when compared to any other cancer patients. Their research is published in the open access journal Research Ideas and Outcomes. (2016-04-11)

Research leads to call for lung health screening at top football clubs
New research from the University of Kent has discovered that nearly three in 10 elite footballers at top clubs in England have undetected lung and airway problems that could impair their on-field performance. The findings of this study will be presented at a British Thoracic Society meeting on Dec. 8 by lead researcher Anna Jackson, who will also call for all top football clubs to implement a lung health screening program. (2017-12-08)

High levels of estrogen in lung tissue related to lung cancer in postmenopausal women
Researchers from Kumamoto University, Japan have found that postmenopausal women with multicentric adenocarcinoma of the lung have a higher concentration of estrogen in non-cancerous areas of the peripheral lung than similar women diagnosed with single tumor lung cancer. The research is an extension of their previous investigation into a gene mutation found to be related to an increased risk of multicentric lung cancer. (2016-10-25)

Dartmouth study reveals how fungal biofilm structure impacts lung disease
Findings from an innovative new study led by researchers at Dartmouth's Geisel School of Medicine and published this week in Nature Microbiology reveal that the way in which human fungal pathogens form colonies can significantly impact their ability to cause disease. Understanding how these colonies form could lead to new therapies that target these infections in critically ill patients. (2019-09-23)

PETA science group promotes animal-free science at society of toxicology conference
The PETA International Science Consortium Ltd. is presenting two posters on animal-free methods for testing inhalation toxicity at the 56th annual Society of Toxicology (SOT) meeting March 12 to 16, 2017, in Baltimore, Maryland. This meeting is the largest international conference of its kind, drawing approximately 7,000 scientists from more than 50 countries each year. (2017-03-16)

Regular exercise halves complication rate after lung cancer surgery
Exercising regularly before surgery for lung cancer halves the complication rate afterwards, finds a synthesis of the available published evidence in the British Journal of Sports Medicine. (2018-02-01)

NIH researchers report first 3-D structure of DHHC enzymes
The first three-dimensional structure of DHHC proteins -- enzymes involved in many cellular processes, including cancer -- explains how they function and may offer a blueprint for designing therapeutic drugs. (2018-01-11)

Blood test shows potential for early detection of lung cancer
A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests. (2018-06-02)

Huntsman Cancer Institute research holds promise for personalized lung cancer treatments
New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah uncovered distinct types of tumors within small cell lung cancer that look and act differently from one another. Scientists also identified a targeted drug combination that worked well with one specific tumor type. The study was published today in Cancer Cell. The findings suggest small cell lung cancer should not be treated as a uniform disease. (2017-01-12)

Childhood body composition may help determine future lung health
Boys and girls with more muscle mass in childhood and adolescence have higher lung function. (2019-01-11)

Did prolonged breastfeeding reduce risk of asthma, atopic eczema in adolescents?
A breastfeeding program appeared to reduce the development of atopic eczema (an allergic skin response) but not asthma and lung function among children at age 16. (2017-11-13)

Alectinib provides longer symptom improvement than crizotinib in ALK-positive lung cancer
The findings of the ALEX trial presented at the ELCC (European Lung Cancer Congress) 2018 in Geneva, Switzerland, support the use of alectinib as the new standard of care in the frontline treatment of ALK-positive lung cancer. Alectinib was found to provide longer symptom improvement than crizotinib in ALK-positive non-small-cell lung cancer. (2018-04-12)

Declines in lung cancer death rates among US women have lagged in 2 hot spots
While lung cancer death rates among women in most of the United States have declined substantially in recent years, progress among women in a region covering central Appalachia and southern parts of the Midwest and in northern parts of the Midwest has lagged. (2018-03-30)

Single steroid-bronchodilator treatment for control and rescue improves persistent asthma
When it comes to treating teens and adults with persistent asthma, using a single corticosteroid and long-acting bronchodilator treatment for both daily asthma control and for rescue relief during sudden asthma attacks is more effective than taking separate medications for daily control and rescue, according to an analysis led by University of Connecticut researchers. (2018-03-19)

'Red tide toxins' leave beachgoers breathless
A new study in the January 2007 issue of the journal CHEST shows that the ecological phenomenon, known as Florida red tide, can be harmful for people with asthma. (2007-01-08)

Exploring 'clinical conundrum' of asthma-COPD overlap in nonsmokers with chronic asthma
Researchers may be closer to finding the mechanism responsible for loss of lung elastic recoil and airflow limitation in nonsmokers with chronic asthma. The study published today in the journal CHEST Unraveling the Pathophysiology of the Asthma-COPD Overlap Syndrome reported that both nonsmokers and smokers with chronic asthma share features of COPD. This conundrum, often referred to as asthma-COPD overlap syndrome, has been assumed to be due to large and especially small airway remodeling. (2015-08-05)

Children's Hospital scientists identify possible target for prevention and treatment of pneumonia
Researchers at Children's Hospital of Pittsburgh of UPMC have identified a key protein target that may be a crucial factor in the development of a vaccine to prevent and new therapies to treat pneumonia, the leading killer of children worldwide. (2008-02-11)

How bone cells promote lung cancer growth
A certain type of cell in the bone marrow can help promote tumor growth in mice with early stage lung cancer, a new study finds. (2017-11-30)

Kidney disease biomarker may also be a marker for COPD
A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. (2018-09-28)

Early-life events linked to lung health in young adulthood
Early-life events, such as the exposure to air pollutants, increases the risk of chronic lung disease in young adulthood, according to new results by researchers at Karolinska Institutet, Sweden, published in the European Respiratory Journal and Thorax. The studies add to the growing evidence that chronic lung disease in adulthood can be traced back to childhood. (2020-11-12)

High EGFR expression a predictor for improved survival with cetuximab plus chemotherapy
High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer. (2011-07-05)

Air pollution is associated with cancer mortality beyond lung cancer
A large scale epidemiological study associates some air pollutants with kidney, bladder and colorectal cancer death. (2017-10-31)

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