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CWRU nurse researcher surveys infection control practices for home patients
Irena Kenneley, assistant professor of nursing at the Frances Payne Bolton School of Nursing at Case Western Reserve University, conducted a survey of home healthcare practices related to infection control. Kenneley reports in the April issue of the peer-reviewed journal, Home Healthcare Nurse, that home healthcare workers report that they have acquired infections and that the practices to prevent these infections varies from one agency to another. (2012-06-25)

Partnership to develop production system for exciting new antibiotic
Researchers from Plymouth University are collaborating with world-leading industrial biotechnology and synthetic biology business Ingenza, to develop an efficient, scalable microbial production system for epidermicin, a new class of antibiotic being developed for use in the fight against infections caused by antibiotic-resistant bacteria. (2015-09-30)

Expert advisory: VCU study finds simple prevention strategy reducing MRSA infections
High compliance with hand hygiene and focusing on other simple infection control measures on medical, surgical and neuroscience intensive care units resulted in reduced rates of methicillin-resistant Staphylococcus aureus infection by 95 percent in a nine-year study, according to research findings by Virginia Commonwealth University physicians presented during IDWeek 2012. (2012-10-24)

APIC conference to focus on patient safety and 'Targeting Zero' initiatives to reduce HAIs
Strategies for infection prevention, best practices, the changing legal landscape of healthcare-associated infections and emerging multidrug-resistant bacteria are among the topics that will be covered at the Association for Professionals in Infection Control and Epidemiology 35th Annual Educational Conference and International Meeting, June 15-19, in Denver, Colo. The meeting is the largest annual gathering of infection prevention and control professionals from around the world. (2008-05-09)

Tips from the journals of the American Society for Microbiology
The following are tips from the Journals of the American Society for Microbiology: (2009-06-18)

First results from hospital trials testing
The first stage of the US Department of Defense-funded clinical trials exploring the role of hospital touch surfaces in the transmission of infectious pathogens has been completed. The findings show that the most heavily contaminated objects are those in closest proximity to the patients: bed rails, call buttons and chairs were found to have the highest levels of staphylococcus, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci. (2008-10-28)

Skin infections caused by MRSA are cured more often when treated with Pfizer's ZYVOX®
Pfizer's antibiotic ZYVOX® (linezolid injection, tablets, and for oral suspension) is more effective than vancomycin for the treatment of complicated skin and soft tissue infections (cSSTIs) caused by methicillin-resistant Staphylococcus aureus (MRSA), according to the largest MRSA cSSTIs study to date published in Antimicrobial Agents and Chemotherapy. Available in interchangeable IV and oral formulations, ZYVOX is the only oral medicine approved by the U.S. Food and Drug Administration for MRSA infections. (2005-06-01)

Study finds fire stations contaminated with MRSA
MRSA transmission may be occurring in fire stations, according to a study published in the June issue of the American Journal of Infection Control, the official publication of APIC -- the Association for Professionals in Infection Control and Epidemiology. (2011-06-01)

MRSA rates varied dramatically across geographic areas
Rates for MRSA acquired in the community were lower in L.A. than in New York City and stable in San Francisco, Chicago and Raleigh-Durham. (2014-06-02)

New study finds MRSA on the rise in hospital outpatients
The community-associated strain of the deadly superbug MRSA -- an infection-causing bacteria resistant to most common antibiotics -- poses a far greater health threat than previously known and is making its way into hospitals, according to a study in the December issue of Emerging Infectious Diseases. (2009-11-24)

Northeastern researchers have discovered a new treatment to cure MRSA infection
Recent work from Northeastern University Distinguished Professor of Biology Kim Lewis promises to overcome one of the leading public health threats of our time. In a groundbreaking study published Wednesday in the journal Nature, Lewis' team presents a novel approach to treat and eliminate methicillin resistant Staphylococcus aureus, or MRSA, a potent bacterium whose resistance to antibiotics has kept it one step ahead of researchers. That is, until now. (2013-11-13)

New grants expand US infectious disease modeling effort
The National Institutes of Health's Models of Infectious Disease Agent Study adds new research expertise to increase its capacity to simulate disease spread, evaluate different intervention strategies and help inform public health officials and policymakers. (2009-09-03)

Prescription for patient safety
A major reform of the way that NHS hospitals pay for legal liability insurance has led to improvements in patient safety, according to research funded by the Economic and Social Research Council. Offering discounts on insurance premiums to hospitals that meet certain targets has led to falls in MRSA infection rates. (2008-11-30)

Researchers uncover clue in spread of 'superbugs'
A discovery from the Oklahoma Medical Research Foundation has put scientists are one step closer to finding a defense against dangerous antibiotic-resistant bacteria, sometimes called (2008-11-03)

15 human genomes each week
The Wellcome Trust Sanger Institute has sequenced the equivalent of 300 human genomes in just over six months. The Institute has just reached the staggering total of 1,000,000,000,000 letters of genetic code that will be read by researchers worldwide, helping them to understand the role of genes in health and disease. Scientists will be able to answer questions unthinkable even a few years ago and human medical genetics will be transformed. (2008-07-01)

Researchers find 'surprising link' leads toward a new antibiotic
Researchers build a method of looking for molecules that will disturb the balance between them offering a completely different way of looking for a new antibiotic that would be active against the cell wall. (2009-05-28)

'Evolutionary forecasting' for drug resistance
Rice University biochemists are developing a system of (2009-09-21)

MRSA strain in humans originally came from cattle
A strain of bacteria that causes skin and soft tissue infections in humans originally came from cattle, according to a study to be published in mBio, the online open-access journal of the American Society for Microbiology. The researchers who conducted the genetic analysis of strains of Staphylococcus aureus known as CC97 say these strains developed resistance to methicillin after they crossed over into humans around forty years ago. (2013-08-13)

Be gone, bacteria
A team of researchers led by the University of Iowa is recommending clinical guidelines that will cut the post-surgical infection rate for staph bacteria (including MRSA) by 71 percent and 59 percent for a broader class of infectious agents known as gram-positive bacteria. The recommendations come after an extensive review of hospital practices in the US and are published in the British Medical Journal. (2013-06-13)

Staphylococcus aureus Achilles' heels
Staphylococcus aureus is a formidable human pathogen, ranking amongst the leading causes of soft tissue infections, as well as severe pneumonia. One of the bacterium's most impressive weapons is α-toxin, which provokes the destruction of human cells. An international project allowed to identify the components of our cells that modulate the virulence of this toxin, in particular the PLEKHA7 protein. By eliminating expression of the latter, cells gained the ability to recover from α-toxin injury. (2015-10-21)

New antibiotic beats superbugs at their own game
By targeting the gene that confers resistance to antibiotics, a new drug may be able to finally outwit drug-resistant staph bacteria. (2008-07-02)

Light as medicine?
Scientists have known for years that certain wavelengths of light in certain doses can heal, but they are only now uncovering exactly how it works, thanks in large part to research cluster in Milwaukee. (2013-10-21)

Antibacterial wipes can still spread bacteria
A new study by a team of researchers at the Welsh School of Pharmacy, Cardiff University, Wales, UK, has found that antimicrobial-containing wipes currently used to decontaminate surfaces in hospitals can spread pathogens after first use. The research highlights concerns as to the suitability of the wipes currently being deployed and the importance of a routine surveillance program in reducing risks of infection to patients. (2008-06-03)

MRSA is a global problem--perspectives from around the world
MRSA (meticllin-resistant Staphylococcus aureus) is everybody's business, not only that of hospital epidemiologists and a few opinion leaders, conclude experts contributing to a global debate in the October issue of The Lancet Infectious Diseases. (2005-09-21)

Drug-resistant staph infection appears more widespread than previously thought
Infections caused by methicillin-resistant Staphylococcus aureus appears to be more prevalent than previously believed, affecting certain populations disproportionately and is being found more often outside of health care settings, according to a study in the Oct. 17 issue of JAMA. (2007-10-16)

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