Popular Melanoma News and Current Events

Popular Melanoma News and Current Events, Melanoma News Articles.
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New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment. (2018-10-05)

Cancer genomics continued: Triple negative breast cancer and cancer immunotherapy
Continuing PLOS Medicine's special issue on cancer genomics, Christos Hatzis of Yale University, New Haven, Conn., USA and colleagues describe a new subtype of triple negative breast cancer that may be more amenable to treatment than other cases of this difficult-to-treat disease. (2016-12-13)

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported. The news comes from Cancer Statistics, 2020, the latest edition of the American Cancer Society's annual report on cancer rates and trends. (2020-01-08)

US Preventive Services Task Force recommendation statement on behavioral counseling to prevent skin cancer
The US Preventive Services Task Force (USPSTF) recommends behavioral counseling to help reduce the risk of skin cancer from ultraviolet (UV) radiation in persons ages 6 months to 24 years with fair skin types. (2018-03-20)

Researcher creates 'Instagram' of immune system, blending science, technology
Hollings Cancer Center researcher Carsten Krieg, Ph.D., who recently joined the faculty of the Medical University of South Carolina, uses a machine aptly labeled Helios to create a sort of 'Instagram' of a person's immune system. Krieg's work was recently published in Nature Medicine, looking at the prediction of response to immunotherapy in melanoma patients. (2018-03-09)

Investigational drug with immunotherapy may provide new therapeutic opportunity for patients previously treated for kidney and lung cancer
Investigational drug with immunotherapy may provide new therapeutic opportunity for patients previously treated for kidney and lung cancer. Pegilodecakin with pembrolizumab and nivolumab shown to be safe in Phase 1B study (2019-09-25)

Huntsman Cancer Institute research holds promise for personalized lung cancer treatments
New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah uncovered distinct types of tumors within small cell lung cancer that look and act differently from one another. Scientists also identified a targeted drug combination that worked well with one specific tumor type. The study was published today in Cancer Cell. The findings suggest small cell lung cancer should not be treated as a uniform disease. (2017-01-12)

New understanding of why cancer cells move
A University of Hawai'i Cancer Center researcher has identified how some cancer cells are made to move during metastasis. The research provides a better understanding of how cancer spreads and may create new opportunities for cancer drug development. (2017-12-27)

Jumbled chromosomes may dampen the immune response to tumors
How well a tumor responds to immunotherapy may depend in part on whether its chromosomes are intact or in a state of disarray, a new study reports. The finding could help doctors better pinpoint which cancer patients would benefit from immunotherapy. (2017-01-19)

Skin cancers linked with reduced risk of Alzheimer's disease
Previous studies have demonstrated a decreased risk of Alzheimer's disease (AD) in individuals with various cancers, including non-melanoma skin cancers (including squamous cell cancers and basal cell cancers). (2018-04-19)

Different outdoor professions carry different risks for skin cancer
One of the main risk factors for non-melanoma skin cancer (NMSC), the most common cancer worldwide, is solar ultraviolet radiation. (2018-06-06)

Researchers reveal new mechanism to 'activate' the immune system against cancer
A new mechanism for activating the immune system against cancer cells allows immune cells to detect and destroy cancer cells better than before, and most effectively in lung cancer and melanoma. (2019-01-04)

Release of the cancer incidence and survival statistics for Northern Ireland 2012-2016
The Queen's University N. Ireland Cancer Registry (NICR) today released the number of new cancer cases diagnosed (incidence) in Northern Ireland in 2016. (2018-03-22)

MD Anderson study may explain why immunotherapy not effective for some patients with metastatic melanoma and kidney cancer
White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. Study results will be presented April 2 at the AACR Annual Meeting 2019 in Atlanta. (2019-03-25)

Novel compound restores immune response in patients with melanoma
A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017. (2017-12-08)

Ludwig researchers uncover novel mechanism by which tumors evade cancer immunotherapies
A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy. (2017-11-10)

Droplet Digital PCR enables precise detection and quantification of a promoter mutation prevalent in many cancer types
Research from NYU Langone Medical Center and its Perlmutter Cancer Center along with Bio-Rad's Digital Biology Group demonstrates how two new ddPCR-based assays can specifically detect and quantify mutations linked to many cancer types. (2018-10-30)

Radiation-guided nanoparticles zero in on metastatic cancer
Zap a tumor with radiation to trigger expression of a molecule, then attack that molecule with a drug-loaded nanoparticle. (2016-06-29)

Limiting tumors' ability to hide from the immune system
Scientists have discovered a way to stop tumors from shedding certain proteins that the immune system uses to identify and attack tumors. (2018-03-29)

Is teledermoscopy cost-effective in Australia for skin cancer referrals?
An analysis estimates using teledermoscopy (dermatologic care that uses information and communications technology and digital dermoscopic images) in Australia for skin cancer referrals would cost extra per case but could achieve clinical resolution faster. (2018-05-09)

Deep learning algorithm does as well as dermatologists in identifying skin cancer
In hopes of creating better access to medical care, Stanford researchers have trained an algorithm to diagnose skin cancer. (2017-01-25)

A better test for the tumor-targeting of CAR-T therapies
Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies, in which the immune system's T cells are extracted from a patient, engineered to target a specific tumor-associated molecule and then grown and reinfused for cancer treatment. (2020-11-06)

Combination approach shows promise for beating advanced melanoma
A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer. (2018-08-28)

Rare melanoma type highly responsive to immunotherapy
Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas. Treatment is difficult because these tumors are often resistant to chemotherapy and lack actionable mutations commonly found in other types of melanoma. However, Moffitt Cancer Center researchers report in the Jan. 10 issue of Nature that patients with desmoplastic melanoma are more responsive to immune-activating therapies than previously assumed. (2018-01-10)

Researchers create novel compound targeting melanoma cells
An international team of researchers has developed a novel compound that successfully inhibits growth of melanoma cells by targeting specific epigenetic modifying proteins in these cells. (2018-01-04)

Vitamin therapy may help prevent melanoma
A new review highlights the potential of nicotinamide (vitamin B3) for preventing melanoma in high-risk individuals. (2017-08-09)

Cancer cells send out 'drones' to battle immune system from afar
Checkpoint inhibitor therapies have made metastatic melanoma and other cancers a survivable condition for 20 to 30 percent of treated patients, but clinicians have had very limited ways of knowing which patients will respond. Researchers have uncovered a novel mechanism by which tumors suppress the immune system. Their findings also usher in the possibility that a straightforward blood test could predict and monitor cancer patients' response to immunotherapy. (2018-08-08)

Enter the exosome: WVU researcher studies how cancer and immune cells communicate
David Klinke, a researcher with the West Virginia University School of Medicine and Cancer Institute, is deciphering the contents of exosomes that cancer cells release. Studying the information exosomes contain and how they influence other cells may suggest new targets for cancer immunotherapy. (2019-10-30)

NYU researchers demonstrate activity of mebendazole in metastatic melanoma
Researchers at the NYU Cancer Institute and the Ronald O. Perelman Department of Dermatology have identified mebendazole, a drug used globally to treat parasitic infections, as a novel investigational agent for the treatment of chemotherapy-resistant malignant melanoma. (2008-08-07)

Head and neck cancer survivors at increased risk of suicide
Despite improved survival rates among cancer patients, the risk of death by suicide remains high, especially among those treated for head and neck cancers. (2018-10-25)

Family members without inherited mutation have increased risk of melanoma
In families who carry certain inherited mutations that increase the risk for melanoma, members who do not carry the mutation also have an increased risk of melanoma, a study from Karolinska Institutet published in Genetics in Medicine reports. The phenomenon, which is called phenocopy, could result from other shared risk-enhancing genes or environmental factors within the families. (2017-12-08)

Deeper look at biopsy exposes mutation ready to ambush drug combination
A powerful resistance mutation that appeared to emerge in melanoma after a patient received a targeted therapy combination, instead was lurking in the tumor all along, primed to thwart treatment before it began, researchers at The University of Texas MD Anderson Cancer Center report online at Cancer Discovery. (2018-03-02)

Man against machine: AI is better than dermatologists at diagnosing skin cancer
Researchers have shown for the first time that a form of artificial intelligence or machine learning known as a deep learning convolutional neural network (CNN) is better than experienced dermatologists at detecting skin cancer. The study is published in the leading cancer journal Annals of Oncology. (2018-05-28)

New data provides guidance for management of moderately dysplastic moles
Study suggests close observation is a reasonable management strategy for moderately dysplastic moles, but certain patients require continued screening for risk for melanoma. (2018-10-26)

Good-guy bacteria may help cancer immunotherapies do their job
Individuals with certain types of bacteria in their gut may be more likely to respond well to cancer immunotherapy, researchers at the Harold C. Simmons Comprehensive Cancer Center found in a study of patients with metastatic melanoma. (2017-10-05)

New therapeutic antibody for dog cancers
Scientists have developed a new chimeric antibody that suppresses malignant cancers in dogs, showing promise for safe and effective treatment of intractable cancers. (2017-08-24)

AACR: How do melanoma cells survive drug treatment long enough to acquire drug resistance?
'What we find is that dabrafenib, even at high doses, does not fully turn off the MAPK pathway, thereby enabling eventual escape from drug,' says Sabrina Spencer, Ph.D. (2018-04-16)

B cells linked to immunotherapy for melanoma
Immunotherapy uses our body's own immune system to fight cancer. Many current immunotherapies focus on T cells, but new research shows that another type of cell, B cells, might also play an important part in immunotherapies for cancer. (2019-09-13)

Targeted therapy plus chemotherapy may pack 1-2 punch against melanoma
By targeting and disabling a protein frequently found in melanoma tumors, doctors may be able to make the cancer more vulnerable to chemotherapy, according to a new study by researchers in the Duke Comprehensive Cancer Center. (2008-05-15)

New combined treatment shows promise in hepatocellular carcinoma
New combined treatment shows promise in Hepatocellular Carcinoma. A combination of mTOR inhibitors and Phenformin leads to an increase in overall survival. (2018-06-27)

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