Popular Mesothelioma News and Current Events

Popular Mesothelioma News and Current Events, Mesothelioma News Articles.
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Increase in lifestyle-related cancers over past decade spotlights need for prevention
Lifestyle-related cancers, such as lung, colorectal, and skin cancers, have increased globally over the past decade, according to the most comprehensive analysis of cancer-related health outcomes and patterns ever conducted. (2018-06-02)

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant meso
Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system. (2019-11-05)

Subset of carbon nanotubes poses cancer risk similar to asbestos in mice
Researchers have shown for the first time in mice that long and thin nanomaterials called carbon nanotubes may have the same carcinogenic effect as asbestos: they can induce the formation of mesothelioma. The findings were observed in 10 percent -- 25 percent of the 32 animals included in the study, which has not yet been replicated in humans. The work appears Nov. 6 in Current Biology. (2017-11-06)

Advocacy and community health care models complement research and clinical care
Global lung cancer researchers and patient advocates today emphasized that new models of delivering care and communicating about cancer care play an important role in the fight against lung cancer. Their remarks come on the first day of the IASLC 17th World Conference on Lung Cancer in Vienna, Austria. (2016-12-04)

Little evidence for any direct impact of national cancer policies on short-term survival in England
A study published by The BMJ today finds little evidence for any direct impact of national cancer policy initiatives implemented since 2000 on short term cancer survival in England. (2018-03-14)

Cancer researchers highlight clinical potential of liquid biopsy using droplet digital PCR technology at the 2019 AACR Annual Meeting
Research studies supporting the clinical utility of droplet digital PCR powered liquid biopsy will be presented during this year's AACR Annual Meeting. (2019-03-29)

Mesothelioma trial suggests immunotherapy as an alternative to chemotherapy
Patients with mesothelioma may gain similar benefit from immunotherapy as chemotherapy, and good responders may provide important clues to novel treatment for the thousands of new cases each year. Data from the PROMISE-meso trial presented at the ESMO Congress 2019 highlight the need to understand the biological mechanisms whereby mesothelioma, which is incurable, adapts to immunotherapy in some patients but not in others, resulting in variations in treatment response. (2019-09-30)

The body's defence mechanisms: Teamwork is key for cancer-fighting proteins
A new study published in Nature Communications shows that a molecular symbiosis between BAP1 and ASXL2 proteins can suppress cancerous tumors. (2018-10-25)

Rare genetic cause of peritoneal mesothelioma points to targeted therapy
BWH investigators have uncovered a new genetic cause of mesothelioma: a genetic rearrangement in the ALK gene, observed in three patients with peritoneal mesothelioma. Unlike previously known causes, this new discovery points to a potential therapeutic approach for those few patients whose tumors harbor the mutation. The team's findings are published in JAMA Oncology. (2017-09-14)

Clinical trial finds therapy to be well-tolerated in patients with aggressive brain tumour
A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients. (2019-03-29)

Genomics provide hope for those with 'one in a million' cancer diagnosis
New research has shown that many people with rare cancers can benefit from genomic profiling. The findings of the patient-driven trial are being presented today at the Clinical Oncology Society of Australia Annual Scientific Meeting and could result in dramatic changes to the way those with rare cancers are diagnosed and treated. (2018-11-13)

Early research suggests first immunotherapy for mesothelioma on the horizon
Malignant pleural mesothelioma or MPM is a rare cancer, but its incidence has been rising. This cancer is usually associated with asbestos exposure, and patients have a median life expectancy of only 13-15 months. All patients relapse despite initial chemotherapy, more than 50% of them within six months after stopping treatment. There are currently no effective therapeutic options for patients with MPM. (2017-06-05)

Mesothelin-targeted CAR T-cell therapy shows early promise in patients with solid tumors
A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity and had antitumor activity in patients with malignant pleural disease from mesothelioma, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-03-31)

The test that reveals cancer sooner
MorNuCo Laboratories' clinical trial, recently published in Clinical Proteomics, demonstrated the ability of a serum test to detect the presence of mesothelioma 4-10 years in advance of clinical symptoms. The ONCOblot® Test detects ENOX2 proteins present in serum, and in this trial, ENOX2 proteins that are specific to mesothelioma. This is an exciting step forward in the continued development of tools for early cancer detection. (2016-02-04)

Shining light on a malignant lung cancer
Treating a rare type of malignant lung cancer could improve, thanks to near-infrared irradiation and a cancer-targeting compound. Nagoya University oncologist Kazuhide Sato and colleagues tested the treatment and published their findings in the journal Cells. (2020-06-20)

Combination immunotherapy improves survival in mouse models of mesothelioma
Massachusetts General Hospital investigators have found that combined treatment with two cancer immunotherapy drugs -- one a novel immune modulator and one that focuses and activates the anti-tumor immune response -- significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma. (2018-04-02)

Clinical trial confirms novel EGFR antibody targets tumors but not normal tissues
The Ludwig Institute for Cancer Research (LICR) and Life Science Pharmaceuticals (LSP) today announced the results of the first clinical trial of monoclonal antibody (mAb) 806, which demonstrate that 806 specifically targets epidermal growth factor receptor (EGFR) on a wide range of tumor types but has no uptake by normal tissues. This result is markedly different to other mAbs, which target wild-type EGFR on normal tissues. (2006-06-05)

Landmark asbestos study published in The Lancet Public Health
A landmark study from The Australian National University into the health impacts of living in a house with loose-fill asbestos insulation has been published in the international journal The Lancet Public Health. (2017-11-01)

Scientific advances in thoracic oncology in 2016 highlighted by the IASLC
Capturing and summarizing the remarkable progress in lung cancer prevention, diagnosis, staging and treatment in 2016, the International Association for the Study of Lung Cancer (IASLC) announces the second annual publication of 'Scientific Advances in Thoracic Oncology,' available online now and in the August 2017 issue of the IASLC's Journal of Thoracic Oncology (JTO). (2017-06-08)

Tiny golden bullets could help tackle asbestos-related cancers
Gold nanotubes - tiny hollow cylinders one thousandth the width of a human hair - could be used to treat mesothelioma, a type of cancer caused by exposure to asbestos, according to a team of researchers at the Universities of Cambridge and Leeds. (2020-10-26)

Possible vaccine for mesothelioma proven safe
Researchers have demonstrated the safety of a potential vaccine against mesothelioma, a rare cancer associated primarily with asbestos exposure. The vaccine, which infuses uses a patient's own dendritic cells with antigen from the patient's tumor, was able to induce a T cell response against mesothelioma tumors. (2010-03-04)

Radiotherapy doubles survival for patients with mesothelioma
Mesothelioma patients are twice as likely to survive for two years or longer, if they are treated with a high dose of radiation to the affected side of the trunk, according to research presented at the ESTRO 38 conference. (2019-04-28)

NYU's Perlmutter Cancer Center & the Technion launch global cancer research initiative
Drug-carrying 'nanoghosts' that battle melanoma and new treatments for malignant mesothelioma will be the focus of the first joint research projects led by NYU Langone Medical Center and the Technion-Israel Institute of Technology. (2016-04-21)

New research group offers hope to asbestosis sufferers
The Asbestos Research Group, offering hope to sufferers of asbestos-related diseases, was launched at the Wesley Research Institute today. (2008-06-11)

Study links BAP1 protein to tumor suppression in kidney, eye, bile duct and mesothelioma cancers
Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate professor, Department of Experimental Radiation Oncology, were published in the Sept. 10 online issue of Nature Cell Biology. (2018-09-10)

Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice
Currently, there are few effective treatments for malignant mesothelioma, although it has been decades since it was found that the major risk factor is exposure to asbestos. The drugs identified by CNIO researchers are being tested on other types of cancer, which can speed up clinical trials for mesothelioma. The authors identified molecular markers that could be used to determine which patients could benefit most from this new therapy, provided that it is approved. (2020-01-08)

Pulmonary artery thrombosis a complication of radiation therapy
According to ARRS' American Journal of Roentgenology, the imaging findings of in situ pulmonary artery thrombosis (PAT) associated with radiation therapy (RT) are different from those of acute pulmonary emboli and do not appear to embolize. Due to the differences in clinical prognosis and subsequent management strategies, in situ PAT associated with RT -- which has not previously been described in the English literature -- must be distinguished from pulmonary embolism. (2020-10-09)

Study finds how NF-2 gene mutations make cells hyper-responsive to growth factor signaling
A team of Massachusetts General Hospital (MGH) Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation. (2018-08-28)

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant...
Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system. Comparing NSCLC PE and published plasma levels of CAR-T recipients, both were dominated by sIL-6R and IL-6 but NSCLC PE had more VEGF, FGF2 and TNF, and less IL-2, IL-4, IL-13, IL-15, MIP1 and IFN. (2019-11-22)

Contaminated poliovirus vaccine not associated with cancer
Exposure to poliovirus vaccine that was contaminated with simian virus 40 (SV40) does not appear to be associated with increased cancer incidence in Denmark, according to a large population-based study appearing in the April 2 issue of the Journal of the National Cancer Institute. (2003-04-01)

Diagnosing cancer
Scientists have established a process for identifying biomarkers for the diagnosis of different types of cancer. With the aid of a specific type of infrared spectroscopy, the researchers applied an automated and label-free approach to detect tumor tissue in a biopsy or tissue sample. This, in turn, facilitates detailed protein analyses in the next step. (2017-04-03)

Study suggests improvements in how mesothelioma is staged
A new study suggests that significant improvements could be made in the scoring system physicians use to estimate the stage (severity) of mesothelioma, an aggressive and deadly cancer. (2016-02-02)

Immunotherapy with live bacterium improves response rate in malignant pleural mesothelioma
Immunotherapy with a live bacterium combined with chemotherapy demonstrated more than 90% disease control and 59% response rate in patients with malignant pleural mesothelioma (MPM), according to the results of a phase Ib trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland. (2016-04-14)

Nivolumab effective treatment for malignant mesothelioma
Nivolumab monotherapy is an effective treatment option for relapsed malignant mesothelioma (MM), according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer. (2021-01-30)

Novel cancer vaccine holds promise against ovarian cancer, mesothelioma
A novel approach to cancer immunotherapy may provide a new and cost-effective weapon against some of the most deadly tumors, including ovarian cancer and mesothelioma. Massachusetts General Hospital investigators report that a protein engineered to combine a molecule targeting a tumor-cell-surface antigen with another protein that stimulates several immune functions prolonged survival in animal models of both tumors. (2014-03-05)

Trial targets deadly lung cancer
With more than 650 Australians diagnosed with malignant mesothelioma last year, Flinders University is leading new research to discover alternatives to chemotherapy and even prevent deaths by early detection in future. One novel approach, using natural therapeutic benefits of curcumin, a key component of the spice turmeric, will be put to the test in a clinical trial in 2021 as part of world-leading research at Flinders University. (2020-10-30)

Asbestos use in Asia poses serious health dangers
The use of asbestos continues to increase in Asia despite clear health hazards. A recent Respirology review notes that with approximately 4.3 billion people and a growing population, Asia will likely see a large crop of asbestos-related lung diseases in the next few decades. (2015-04-07)

IASLC gives 5 people travel awards
The International Association for the Study of Lung Cancer awarded five people Advocacy Travel Awards. Awardees receive free conference registration, up to four nights' accommodations, a free IASLC Membership and travel stipend. (2013-10-16)

Beijing conference to address lung cancer crisis in China
The first international lung cancer conference to be held in China will take researchers to Beijing October 27-30. UCSF, in collaboration with the University of Colorado Health Sciences Center and the Chinese Academy of Medical Sciences, is sponsoring the event. (2002-10-23)

UH Case Medical Center offers new therapy for gynecologic cancer patients
Patients with gynecologic cancer have new hope in a novel technology now offered at the Seidman Cancer Center at University Hospitals Case Medical Center. A team of cancer specialists, led by Robert DeBernardo, M.D., is among the first in the nation to launch a dedicated program using Hyperthermic Intraperitoneal Chemotherapy to treat ovarian, endometrial and select other cancers. (2012-01-20)

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