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Popular Mitochondria News and Current Events

Popular Mitochondria News and Current Events, Mitochondria News Articles.
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Big data studies scrutinize links between fatty liver disease and how cells make energy
Three recent studies investigate changes in mitochondria, the cell's energy producers, as fatty liver disease (NAFLD) progresses to steatohepatosis (NASH). (2018-09-14)
Key protein in cellular respiration discovered
Many diseases derive from problems with cellular respiration, the process through which cells extract energy from nutrients. (2009-04-08)
Chlamydia: How bacteria take over control
To survive in human cells, chlamydiae have a lot of tricks in store. (2017-03-28)
Discovering, counting, cataloguing proteins
Scientists describe a well-defined mitochondrial proteome in baker's yeast. (2017-06-28)
TSRI researchers uncover culprit in Parkinson's brain cell die-off
Researchers investigate the connection between misfolded proteins and the destruction of mitochondria in neurons. (2018-03-05)
Why can't mTOR inhibitors kill cancer? Study explains
Anti-cancer drugs called mTOR inhibitors slow the growth of cancer cells but show limited ability to cause cancer cell death. (2017-10-05)
Healthy mitochondria could stop Alzheimer's
Using a bioinformatics and experimental approach, scientists at EPFL have found that rendering mitochondria resistant to damage can halt diseases caused by amyloid toxicity, such as Alzheimer's disease. (2017-12-06)
Researchers find ways to impede progress of neurodegenerative diseases
As the paper posits, there is currently no doubt that hyperpolarization of mitochondria and concomitant oxidative stress are associated with the development of serious pathologies, such as Parkinson's disease, Alzheimer's disease, autoimmune syndromes, some cancers, and other conditions. (2018-03-30)
Substance in red wine found to keep hearts young
Scientists included small amounts of resveratrol in the diets of middle-aged mice and found that the compound has a widespread influence on the genetic causes of aging. (2008-06-04)
How a genetic mutation can interfere with the powerhouses of cells
A Freiburg molecular medicine specialist's team discovers a new disease mechanism in the mitochondria. (2018-03-23)
Mitochondrial protein in cardiac muscle cells linked to heart failure, study finds
Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure, a finding that could provide insight for new treatments for cardiovascular diseases, a study led by Georgia State University has shown. (2017-12-05)
Digging deep into distinctly different DNA
A University of Queensland discovery has deepened our understanding of the genetic mutations that arise in different tissues, and how these are inherited. (2018-01-22)
Three papers help to crack the code of coenzyme Q biosynthesis
Coenzyme Q (CoQ) is a vital cog in the body's energy-producing machinery, a kind of chemical gateway in the conversion of food into cellular fuel. (2017-12-13)
Do our mitochondria run at 50 degrees C?
A new study publishing Jan. 25 in the open-access journal PLOS Biology by INSERM and CNRS researchers at Hôpital Robert Debré in Paris led by Dr. (2018-01-25)
How mitochondria cope with too much work
Researchers have uncovered a mechanism by which mitochondria, essential organelles within cells that create energy, cope with an overload of imported proteins. (2018-04-12)
Active young adults with Type 1 diabetes have muscle complications: Study
A new study from McMaster and York universities has found that poor muscle health may be a complication of Type 1 diabetes, even among active twenty-somethings. (2018-04-18)
Vitamin K2: New hope for Parkinson's patients?
Neuroscientist Patrik Verstreken, associated with VIB and KU Leuven, succeeded in undoing the effect of one of the genetic defects that leads to Parkinson's using vitamin K2. (2012-05-11)
Brain cell powerhouses appear good treatment target for stroke, TBI recovery
Cell powerhouses are typically long and lean, but with brain injury such as stroke or trauma, they can quickly become bloated and dysfunctional, say scientists who documented the phenomena in real time for the first time in a living brain. (2017-01-09)
Malignant mitochondria as a target
Killing malignant mitochondria is one of the most promising approaches in the development of new anticancer drugs. (2017-12-13)
UNSW research on reversing negative effects of maternal obesity
A drug that increases energy metabolism may lead to a new approach to prevent obesity in children born to overweight mothers, UNSW Sydney researchers have found. (2017-11-08)
A link between mitochondria and tumor formation in stem cells
Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -- a cell's energy makers. (2008-10-10)
Broken mitochondria use 'eat me' proteins to summon their executioners
When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them. (2019-04-11)
Could statins ease deadly heart condition in rare neuromuscular disease?
Decreased HDL and ApoA-l levels in the general population are associated with an increased risk of death from cardiomyopathy and heart failure. (2018-04-17)
Energy supply channels
Freiburg scientists elucidate the mechanism for inserting protein molecules into the outer compartment of mitochondria. (2018-01-25)
Anxiety-depressive disorder changes brain genes activity
Russian neuroscientists discovered that anxiety-depressive disorder in mice is associated with impaired energy metabolism in the brain. (2019-01-07)
Refrigeration technology to maintain cold-stored mouse sperm viability for 10 days
A Japanese research team has succeeded in developing a refrigeration preservation technology that maintains the fertilization functionality of mouse sperm for 10 days. (2017-12-04)
Salk scientists find power switch for muscles
ERRγ gene enables endurance exercise and repairs type of damage seen in neuromuscular diseases. (2018-03-06)
Cell Biology: Cellular power outage
Protein aggregation is a hallmark of many neurodegenerative diseases. Even in normal cells, such deposits can accumulate in mitochondria, blocking energy production, but a newly described quality control system can mitigate the problem. (2017-10-27)
Mitochondria may metabolize ADP differently in aging muscle, despite exercise resistance
Most adults reach their peak levels of muscle mass in their late 30s or early 40s. (2018-03-13)
Researchers discover key link between mitochondria and cocaine addiction
Scientists at the University of Maryland School of Medicine identified significant mitochondrial changes that take place in cocaine addiction, and they have been able to block them. (2017-12-20)
New research on the muscles of elite athletes: When quality is better than quantity
A Danish-Swedish research team working on a project led by University of Southern Denmark has discovered that muscle endurance is not only determined by the number of mitochondria, but also their structure. (2016-11-02)
A map of the cell's power station
Researchers from the University of Freiburg are mapping the distribution of all proteins in mitochondria for the first time. (2017-08-18)
Penn Vet study uncovers therapeutic targets for aggressive triple-negative breast cancers
New findings from a study led by researchers at the University of Pennsylvania have made inroads into a strategy to identify triple-negative breast cancers at risk for metastasis, and eventually target these cancers with drugs. (2018-02-02)
Target of rapamycin: Linking cytosolic and chloroplast ribosome biogenesis in plants
Scientists at Tokyo Institute of Technology (Tokyo Tech) have found that eukaryotic and bacterial growth regulation systems of independent origins are connected to the control of chloroplast rRNA transcription in a primitive red alga. (2018-02-14)
In a severe childhood neurodegeneration, novel mechanism found
Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells. (2018-03-22)
The bacteria responsible for legionellosis modulates the host cell metabolism to its advantage
Scientists at the Institut Pasteur, CNRS and Inserm, together with a team from Switzerland, have shown that the bacterial pathogen Legionella pneumophila has developed a specific strategy to target the host cell mitochondria, the organelles in charge of cellular bioenergetics. (2017-09-06)
Without 'yoga and chardonnay' leukemia stem cells are stressed to death
University of Colorado Cancer Center researchers nix leukemia stem cell (LSC) stress-relief pathway to kill LSCs without harming healthy blood stem cells, paving the way for new therapies targeting these most dangerous cancer cells. (2018-06-14)
Substance with the potential to postpone aging
The coenzyme NAD+ plays a main role in aging processes. (2016-10-14)
Bascom Palmer Eye Institute announces breakthrough for degenerative vision disorder
A research team, led by John Guy, M.D., professor of ophthalmology at Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine, has pioneered a novel technological treatment for Leber Hereditary Optic Neuropathy, an inherited genetic defect that causes rapid, permanent, and bilateral loss of vision in people of all ages, but primarily males ages 20-40. (2012-04-23)
The absence of a single mitochondrial protein causes severe inflammation
Scientists at the Institute for Research in Biomedicine (IRB Barcelona) headed by Antonio Zorzano, demonstrate that the removal of a single mitochondrial protein in mouse muscle leads to severe inflammation throughout the body, causing the premature death of the animal. (2018-04-09)
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