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Popular Muscle News and Current Events, Muscle News Articles.
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Vitamin D may halt lung function decline in asthma and COPD
Vitamin D may slow the progressive decline in the ability to breathe that can occur in people with asthma as a result of human airway smooth muscle proliferation, according to researchers at the University of Pennsylvania. (2009-05-20)

Diseased hearts to heal themselves in future
Oncostatin M regulates the reversion of heart muscle cells into precursor cells and is vitally important for the self-healing powers of the heart. (2011-11-11)

Scientists turn skin cells into heart cells and brain cells using drugs
In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals. All previous work on cellular reprogramming required adding external genes to the cells, making this accomplishment an unprecedented feat. The research lays the groundwork for one day being able to regenerate lost or damaged cells with pharmaceutical drugs. (2016-04-28)

Common incontinence drug could have an additional topical effect on the bladder itself
Trospium chloride, a commonly prescribed incontinence drug, may benefit patients in more ways than previously thought. Researchers from the University of Pittsburgh found in animal studies that topical application of tropsium to the bladder walls controlled the symptoms of overactive bladder, indicating that the drug helps control symptoms during storage of urine in addition to having benefit during the voiding phase. (2005-05-22)

Potential therapy for congenital muscular dystrophy
Current research suggests laminin, a protein that helps cells stick together, may lead to enhanced muscle repair in muscular dystrophy. The related report by Rooney et al., (2008-12-30)

Gene Therapy For Anemia Succeeds In Animal Model
By injecting custom-built genes into muscle tissue in mice, University of Chicago researchers produced a lasting therapeutic response. This is the first demonstration that an injected gene, without a viral delivery system, could secrete enough protein into the bloodstream to make a clinical difference, and keep doing it indefinitely. (1996-10-01)

Researchers investigate muscle-building effect of protein beverages for athletes
The researchers concluded that muscle metabolism after exercise can be manipulated via dietary means. In terms of the most beneficial timing of protein intake, immediate postexercise consumption appears to be best. (2011-08-18)

Muscular dystrophy mystery solved; Mizzou scientist moves closer to MD solution
While scientists have identified one protein, dystrophin, as an important piece to curing muscular dystrophy, another part of the mystery has eluded scientists for the past 14 years. Now, one University of Missouri scientist and his team have identified the location of the genetic material responsible for a molecular compound that is vital to curing the disease. (2009-02-26)

Gene therapy treats all muscles in the body in muscular dystrophy dogs
Muscular dystrophy, which affects approximately 250,000 people in the US, occurs when damaged muscle tissue is replaced with fibrous, fatty or bony tissue and loses function. For years, scientists have searched for a way to successfully treat the most common form of the disease, Duchenne Muscular Dystrophy (DMD), which primarily affects boys. Now, a team of University of Missouri researchers have successfully treated dogs with DMD and say that human clinical trials are being planned in the next few years. (2015-10-22)

Cause of an inherited neurological disorder discovered
Researchers at the University of Liverpool have identified the basis for how a single gene mutation can cause a rare neurological movement disorder known as dystonia. (2017-04-10)

A no-brainer? Mouse eyes constrict to light without direct link to the brain
Experimenting with mice, neuroscientists at Johns Hopkins Medicine report new evidence that the eye's iris in many lower mammals directly senses light and causes the pupil to constrict without involving the brain. (2017-06-19)

Muscle stem cells compiled in 'atlas'
A team of Cornell researchers led by Ben Cosgrove, assistant professor in the Meinig School of Biomedical Engineering, used a new cellular profiling technology to probe and catalog the activity of almost every kind of cell involved in muscle repair. They compiled their findings into a 'cell atlas' of muscle regeneration that is one of the largest datasets of its kind. (2020-03-10)

Consumption of a blueberry enriched diet by women for six weeks alters determinants of human muscle progenitor cell function
A new research study, published in the Journal of Nutrition, investigated how serum from subjects consuming a diet enriched with blueberries would affect the cells responsible for muscle growth and repair. The emerging study, ''Consumption of a blueberry enriched diet by women for six weeks alters determinants of human muscle progenitor cell function,'' was conducted at Cornell University. (2020-08-05)

A change of heart -- new drug for HCM reduces heart mass
For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, hypertrophic cardiomyopathy, rather than simply addressing their symptoms. (2020-11-16)

NASA study shows that space travel affects spine of astronauts
How does space travel affect the spine? Astronauts on long missions in space have atrophy of the muscles supporting the spine -- which don't return to normal even several weeks after their return to Earth, reports a study in Spine, published by Wolters Kluwer. (2016-10-25)

Muscular dystrophy: Repair the muscles, not the genetic defect
A potential way to treat muscular dystrophy directly targets muscle repair instead of the underlying genetic defect that usually leads to the disease. (2014-09-14)

Hearts build new muscle with this simple protein patch
An international team of researchers has identified a protein that helps heart muscle cells regenerate after a heart attack. Researchers also showed that a patch loaded with the protein and placed inside the heart improved cardiac function and survival rates after a heart attack in mice and pigs. Animal hearts regained close to normal function within four to eight weeks after treatment with the protein patch. (2015-09-16)

Your stroke risk profile may also help predict your risk of memory problems
A new study shows a person's stroke risk profile, which includes high blood pressure, smoking, and diabetes, may also be helpful in predicting whether a person will develop memory and thinking problems later in the life. The research is published in the Nov. 8, 2011, issue of Neurology®, the medical journal of the American Academy of Neurology. (2011-11-07)

First in vivo proof-of-concept in Steinert's myotonic dystrophy
Ana Buj Bello's team, a researcher in an Inserm unit at Genethon, the AFM-Telethon laboratory, has made the proof-of-concept of a CRISPR-Cas9 approach in a mouse model of Steinert's myotonic dystrophy, the most common neuromuscular disease in adults. (2019-06-25)

Experimental model mimics early-stage myogenic deficit in boys with DMD
An experimental model of severe Duchenne muscular dystrophy that experiences a large spike in TGFβ activity after muscle injury shows that high TGFβ activity suppresses muscle regeneration and promotes fibroadipogenic progenitors, Children's National Hospital researchers find. (2020-03-26)

Scientists edge closer to treatment for myotonic dystrophy
Scientists at the University of Nottingham have taken a step closer towards developing a treatment for the long-term genetic disorder, myotonic dystrophy. (2020-04-29)

Stem-cell transplantation improves muscles in MD animal model, UT Southwestern researchers report
Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy -- and more importantly, functioning -- muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy. (2008-01-20)

Training the best treatment for tennis elbow
Training and ergonomic advice are more effective than anti-inflammatory drugs and cortisone injections in treating tennis elbow, and give fewer side effects. This is the conclusion of a thesis presented at the University of Gothenburg, Sweden. (2010-12-20)

Could chocolate and oranges help prevent frailty in old age?
A study by The University of Nottingham is hoping to establish the health benefits from cocoa and vitamin C. Researchers are trying to find ways of helping us maintain muscle mass as we grow old and want to hear from healthy men aged between 18-28 and 65-75. (2011-02-03)

Identification of stem cells raises possibility of new therapies
Many diseases -- obesity, type 2 diabetes, muscular dystrophy -- are associated with fat accumulation in muscle. In essence, fat replacement causes the muscles to weaken and degenerate. Scientists at Wake Forest Baptist Medical Center have discovered the biological mechanism involved in this process, which could point the way to potential therapies. (2013-04-30)

Molecular '2-way radio' directs nerve cell branching and connectivity
Working with fruit flies, Johns Hopkins scientists have decoded the activity of protein signals that let certain nerve cells know when and where to branch so that they reach and connect to their correct muscle targets. The proteins' mammalian counterparts are known to have signaling roles in immunity, nervous system and heart development, and tumor progression, suggesting broad implications for human disease research. A report of the research was published online Nov. 21 in the journal Neuron. (2013-01-07)

Controlling arterial tone and blood flow in the brain
Researchers have performed the first human-based study to identify calcium channels in cerebral arteries and determine the distinct role each channel plays in helping control blood flow to the brain. (2015-04-27)

Artificial muscles bloom, dance, and wave
Researchers from KAIST have developed an ultrathin, artificial muscle for soft robotics. The advancement, recently reported in the journal Science Robotics, was demonstrated with a robotic blooming flower brooch, dancing robotic butterflies and fluttering tree leaves on a kinetic art piece. (2019-08-21)

Gene discovery could help prevent heart attacks
Doctors may be able to use the findings to identify people at high risk of coronary artery disease and to develop better treatments and preventative interventions. (2020-12-10)

Nuclei in wrong place may be cause, not result, of inherited muscle diseases
Researchers solve puzzle of whether out-of-position cell nuclei are cause or consequence of congenital muscle diseases. (2013-12-16)

Exercise helps young baleen whales develop ability to store oxygen for extended dives
Baleen whale calves develop oxygen-carrying myoglobin as they mature, and exercise may drive the key component of early development, according to a study published Jan. 20, 2016 in the open-access journal PLOS ONE by Rachel Cartwright from the California State University, Channel Islands, and colleagues. (2016-01-20)

Beyond broke bones, CTs also detect frailty and predict survival
Using computed tomography (CT) to evaluate muscle health may help identify optimal treatments for older patients who fall and break their hips, a new study led by radiologists from UC Davis and Wake Forest Baptist medical centers has found. (2017-06-01)

Learning from the bears
Grizzly bears spend many months in hibernation, but their muscles do not suffer from the lack of movement. In the journal 'Scientific Reports', a team led by MDC researcher Michael Gotthardt reports on how they manage to do this. The grizzly bears' strategy could help prevent muscle atrophy in humans as well. (2019-12-30)

Evidence of a human segmentation clock reveals how an embryo's vertebrae tick
To reproduce the molecular steps that lead to the proper formation of the human spine, investigators from Brigham and Women's Hospital have developed a model in a dish, allowing them to study just what makes our segmentation clock tick. (2020-01-08)

Growing new blood vessels could provide new treatment for recovering movement
New research published today in The Journal of Physiology highlights the link between loss of the smallest blood vessels in muscle and difficulties moving and exercising. (2020-02-06)

Research brief: Researchers 3D print a working heart pump with real human cells
In a groundbreaking new study, researchers at the University of Minnesota have 3D printed a functioning centimeter-scale human heart pump in the lab. The discovery could have major implications for studying heart disease, the leading cause of death in the United States killing more than 600,000 people a year. (2020-07-15)

Exosome treatment improves recovery from heart attacks in a preclinical study
Research in pigs shows that using the exosomes naturally produced from a mixture of heart muscle cells, endothelial cells and smooth muscle cells -- which were all derived from human induced pluripotent stem cells -- yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells. (2020-09-29)

Into thin air and back
In a new publication in the journal Molecular Biology and Evolution, Scott, Cheviron et al., have examined the underlying muscle physiology from a group of highland and lowland deer mice. Population differences were associated with changes in the expression of in a number of genes involved in energy metabolism, muscle plasticity, vascular development and cellular stress. (2015-04-07)

Improving clinical use of stem cells to repair heart damage
Presenting at the UK National Stem Cell Network annual science conference July 13, Professor Michael Schneider describes a new approach to treating heart attack and cardiomyopathy using stem cells. (2010-07-13)

Pitt: A shot of young stem cells made rapidly aging mice live longer and healthier
Mice bred to age too quickly seemed to have sipped from the fountain of youth after scientists at the University of Pittsburgh School of Medicine injected them with stem cell-like progenitor cells derived from the muscle of young, healthy animals. Instead of becoming infirm and dying early as untreated mice did, animals that got the stem/progenitor cells improved their health and lived two to three times longer than expected, according to findings in Nature Communications. (2012-01-03)

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