Popular Neutrophils News and Current Events

Popular Neutrophils News and Current Events, Neutrophils News Articles.
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MicroRNA could help treat cancer and asthma
MiR-223 shows promise for treating inflammatory disease. (2018-02-20)

Cancer researchers train white blood cells to attacks tumor cells
Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program -- be utilized for the treatment of tumors. The scientists published their results in the renowned specialist journal Cell. (2020-11-06)

Immune cells halt fungal infection by triggering spore suicide
To protect the body from infection, immune cells in the lungs can exploit cell death programs in inhaled fungal pathogens, scientists have revealed, helping explain why most people aren't harmed by breathing in mold spores, and potentially offering new therapeutic strategies for people who do get infected. (2017-09-07)

Experimental drug reverses hair loss and skin damage linked to fatty diet, shows new study in mice
In a series of experiments with mice, Johns Hopkins investigators have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol. (2018-07-30)

Asthma in many adolescents is not an allergic disease
New research indicates that asthma in many adolescents is not likely to involve inflammation of the airways and therefore should not be considered an allergic disease. (2016-01-13)

Test can identify patients in intensive care at risk of life-threatening infections
Patients in intensive care units are at significant risk of potentially life-threatening secondary infections, including from antibiotic-resistant bacteria such as MRSA and C. difficile. Now, a new test could identify those at greatest risk -- and speed up the development of new therapies to help at-risk patients. (2018-06-13)

How bone cells promote lung cancer growth
A certain type of cell in the bone marrow can help promote tumor growth in mice with early stage lung cancer, a new study finds. (2017-11-30)

Cardiovascular disease: The immune response to heart attacks
The damage caused by a heart attack triggers an inflammatory reaction which degrades the affected tissue. This response is orchestrated by immune cells that reside in the nearby pericardial adipose tissue, as a study by a team of Ludwig-Maximilians-Universitaet (LMU) in Munich shows. (2017-11-28)

Cell cycle proteins help immune cells trap microbes with nets made of DNA
In your bloodstream, there are immune cells called neutrophils that, when faced with a pathogenic threat, will expel their DNA like a net to contain it. These DNA snares are called neutrophil extracellular traps or NETs. Researchers from Germany and the United States describe an important step in how these NETs are released and how they stop a fungus from establishing an infection in mice and human cells in the journal Developmental Cell. (2017-11-20)

How the human immune system protects against Ebola
'The current approach for treatment of filovirus infections with antibody cocktails tested in animal models utilizes the principle of targeting of non-overlapping epitopes. Our study suggests that possible synergistic effects of antibodies which block various steps of viral replication should be also considered.' (2018-08-23)

Antibiotic treatment targets difficult asthma
Hunter researchers have shown that a commonly available antibiotic can improve the quality of life of patients with difficult asthma, and may also generate significant health care savings. (2007-12-17)

Nanoparticles can limit inflammation by distracting the immune system
A surprise finding suggests that an injection of nanoparticles may be able to help fight the immune system when it goes haywire, researchers at the University of Michigan have shown. The nanoparticles divert immune cells that cause inflammation away from an injury site. (2017-11-08)

Research sheds light on a novel disease mechanism in chronic smokers
Research published in the journal Clinical Science suggests that an immune signalling protein called interleukin (IL)-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients. (2018-05-20)

No platelets, no immune response
When a virus attacks our organism, an inflammation appears on the affected area. White blood cells move quickly to the inflamed area. Up until now, it was proved that neutrophils were the first defenders to arrive but today, researchers at the UNIGE discovered that their recruitment onsite depend on a group of patrolling monocytes, referred to as 'residents,' and also on a protein called CCN1, produced by the platelets and by the endothelium. (2016-08-01)

Nerve cells found to suppress immune response during deadly lung infections
Neurons that carry nerve signals to and from the lungs suppress immune response during fatal lung infections with the bacterium Staphylococcus aureus. Animal experiments show that disabling these neurons can boost immune response and promote bacterial clearance to aid recovery. Targeting neuro-immune signaling in the lungs can pave the way to nonantibiotic therapies for bacterial pneumonia. (2018-03-05)

WSU researchers deliver first 'nanotherapeutics' to tumor
For the first time, WSU researchers have demonstrated a way to deliver a drug to a tumor by attaching it to a blood cell. The innovation could let doctors target tumors with anticancer drugs that might otherwise damage healthy tissues. (2017-05-15)

Clinical trial for new innovative osteoarthritis drug
The University of Liverpool, in partnership with AKL Research and Development Ltd, is to lead on a clinical trial to test a potential new drug treatment for osteoarthritis. (2017-02-16)

Mouse healing may reveal targets to delay or prevent human heart failure
In a study of mouse healing after severe heart attacks, which may reveal therapeutic targets that can help humans avoid or delay heart failure, researchers looked at the heart and spleen over time and measured the types and numbers of immune cells involved; the types and amounts of lipid signaling compounds produced; the expression of the enzymes that produce those signaling compounds; and which enzymes are key to resolution of inflammation. (2018-03-06)

Measuring neutrophil motility could lead to accurate sepsis diagnosis
Microfluidic device developed by Massachusetts General Hospital investigators may help solve a significant and persistent challenge in medicine -- diagnosing the life-threatening complication of sepsis. (2018-03-19)

Chlorinated lipids predict lung injury and death in sepsis patients
Researchers studied blood samples taken from patients diagnosed with sepsis and found that elevated chlorinated lipids predicted whether a patient would go on to suffer acute respiratory distress symptom (ARDS) and die within 30 days from a lung injury. (2018-01-31)

Researchers unearth secret tunnels between the skull and the brain
Bone marrow, the spongy tissue inside most of our bones, produces red blood cells as well as immune cells that help fight off infections and heal injuries. According to a new study of mice and humans, tiny tunnels run from skull bone marrow to the lining of the brain and may provide a direct route for immune cells responding to injuries caused by stroke and other brain disorders. (2018-08-27)

NIH scientists describe potential antibody treatment for multidrug-resistant K. pneumoniae
Researchers are developing a promising alternative to antibiotic treatment for infections caused by Klebsiella pneumoniae bacteria resistant to carbapenem antibiotics. The approach uses antibodies to target the K. pneumoniae protective capsule polysaccharide, allowing immune system cells called neutrophils to attack and kill the bacteria. The early stage, in vitro research was conducted by scientists at NIAID's Rocky Mountain Laboratories and the New Jersey Medical School-Rutgers University. (2018-03-13)

Hybrid immune cells in early-stage lung cancer spur anti-tumor T cells to action
Researchers have identified a unique subset of these cells that exhibit hybrid characteristics of two immune cell types -- neutrophils and antigen-presenting cells -- in samples from early-stage human lung cancers. This is the first study to describe this phenomenon in a human tumor. (2016-07-14)

Metabolic syndrome patients need more vitamin C to break cycle of antioxidant depletion
A higher intake of vitamin C is crucial for metabolic syndrome patients trying to halt a potentially deadly cycle of antioxidant disruption and health-related problems, an Oregon State University researcher says. (2019-01-02)

Immunology: How ancestry shapes our immune cells
A genetic variant that is particularly prevalent in people of African ancestry confers protection against malaria. LMU researchers have now shown how it modulates the properties of white blood cells that play a major role in immune defenses and inflammation. (2017-06-01)

A human enzyme can biodegrade graphene
Graphene Flagship partners discovered that a natural human enzyme can biodegrade graphene. These findings could have great implications in the development of graphene-based biomedical devices. (2018-08-23)

Meeting a microbe in the morning or in the evening: Is it all the same?
Does the time of day matter when our body is infected by a parasite? According to new research from McGill University, it matters a great deal. (2017-09-08)

When sequencing fails to pinpoint a rare disease
Genomics fails to diagnose up to half of patients who are tested. German scientists tackled the problem in a recent study in the journal Molecular & Cellular Proteomics. Using a new neutrophil proteome database they made genetic diagnoses for children with severe congenital neutropenia whom typical sequencing had failed. (2019-02-08)

Communication between lung tumors and bones contributes to tumor progression
Massachusetts General Hospital investigators have identified a way in which a type of lung cancer co-opts a portion of the immune system to increase tumor progression. (2017-11-30)

COVID-19: Immune system derails
Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition. Experts from Charité - Universitätsmedizin Berlin, the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE), the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF), along with colleagues from a nationwide research network, present these findings in Cell. (2020-08-06)

Researchers uncover key role for microRNA in inflammatory bowel disease
An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine. The study, 'Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome,' which will be published May 9 in The Journal of Experimental Medicine, shows that synthetic versions of this microRNA can reduce intestinal inflammation in mice and suggests a new therapeutic approach to treating patients with Crohn's disease or ulcerative colitis. (2017-05-09)

Escort service: The role of immune cells in the formation of metastases
Tumor cells use a certain type of immune cells, the so-called neutrophils, to enhance their ability to form metastases. Scientists have deciphered the mechanisms of this collaboration and found strategies for blocking them. This is reported by researchers from the University of Basel and the University Hospital of Basel in the scientific journal Nature. (2019-02-06)

New treatment for children with ARDS
Acute Respiratory Distress Syndrome (ARDS) affects hundreds of thousands of people each year, many of them children. Now, a recent study investigates the effects of a new steroid treatment on children suffering from ARDS. (2016-05-06)

Etosis phenomenon discovered in human blood monocytes
A recent study published online in the Journal of Leukocyte Biology found the first clear demonstration of etosis in human blood monocytes, a type of immune cell. (2017-09-01)

By altering bone marrow, training can prepare innate immune system for future challenges
In a new paper, published in Cell, researchers at the University of Pennsylvania collaborated with an international team to show how the innate immune system, which responds more generally to dangers detected in the body, can be trained to 'remember' past threats and respond more robustly to future challenges. (2018-01-11)

New imaging approach offers unprecedented views of staph infection
Eric Skaar, Ph.D., M.P.H., and colleagues at Vanderbilt have combined multiple types of molecular imaging to probe an invasive Staphylococcus aureus infection in the mouse. Their integrated imaging approach, reported this week in Science Translational Medicine, revealed new insights about staph infections and can be broadly applied to any health or disease state. (2018-03-14)

Could a ketogenic diet alleviate gout?
Recent work from the laboratory of Vishwa Deep Dixit, Professor of Comparative Medicine and Immunobiology, has shown that the ketone body β-hydroxybutyrate can specifically inhibit the NLRP3 inflammasome. They found that feeding rats a high-fat, low-carbohydrate ketogenic diet increased β-hydroxybutyrate levels and protected rats from joint swelling, tissue damage, and systemic inflammation normally seen during gout. (2017-02-28)

Antibiotics found to weaken body's ability to fight off disease
Adding another reason for doctors to avoid the overuse of antibiotics, new research shows that a reduction in the variety of microbes in the gut interferes with the immune system's ability to fight off disease. (2017-08-17)

Surprise rheumatoid arthritis discovery points to new treatment
Researchers have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease. The discovery points to a potential new treatment for the autoimmune disorder and may also allow the use of a simple blood test to detect people at elevated risk for developing the condition. (2019-02-22)

Immune study points to new ways to treat lung disease
Fresh insight into how the immune system keeps itself in check could lead to new ways of fighting chronic lung disease. (2017-08-14)

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