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Popular Osteoporosis News and Current Events, Osteoporosis News Articles.
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Exercise-induced hormone irisin triggers bone remodeling in mice
Exercise has been touted to build bone mass, but exactly how it actually accomplishes this is a matter of debate. Now, researchers show that an exercise-induced hormone activates cells that are critical for bone remodeling in mice. A study appearing in Cell on identifies a receptor for irisin, an exercise hormone, and shows that irisin impacts sclerostin in mice, a major cellular regulator of bone structure in humans. (2018-12-13)

Osteoporosis drug could be used to treat aggressive form of breast cancer, researchers say
Researchers in China have discovered that an enzyme called UGT8 drives the progression of basal-like breast cancer, an aggressive form of the disease that is largely untreatable. But the study, which will be published May 4 in the Journal of Experimental Medicine, reveals that the widely used osteoporosis drug zoledronic acid inhibits UGT8 and prevents the spread of basal-like breast cancer in mice, suggesting that this drug could also be used to treat the disease in humans. (2018-05-04)

Osteoporosis: Antibody crystallized
Inhibiting a protein called Sclerostin could probably help treating the bone-loss disease osteoporosis. New findings at the University of Würzburg could stimulate this research. (2016-09-02)

Probiotics can protect the skeletons of older women
For the first time in the world, researchers at the University of Gothenburg, Sweden, have demonstrated that probiotics, dietary supplements with health-promoting bacteria, can be used to affect the human skeleton. Among older women who received probiotics, bone loss was halved compared to women who received only a placebo. The research opens the door to a new way to prevent fractures among the elderly. (2018-06-21)

Task force provides guidance on use of osteoporosis drugs
A new report by a task force of the American Society for Bone and Mineral Research provides guidance on the use of bisphosphonates, which are the most commonly used medications for osteoporosis. (2016-01-19)

Screening for fracture risk in postmenopausal women is cost-effective
A recent Journal of Bone and Mineral Research analysis indicates that screening for fracture risk in older postmenopausal women is a good use of healthcare resources--in other words, it's cost-effective. (2018-02-23)

New review on management of osteoporosis in premenopausal women
An IOF and ECTS Working Group have published an updated review of literature published after 2017 on premenopausal osteoporosis. It outlines key information on factors affecting peak bone mass and distinguishing low bone mass from proper osteoporosis with increased fracture risk at a young age, causes of secondary osteoporosis versus idiopathic osteoporosis, as well as pregnancy-and lactation-associated osteoporosis. Also provided is a helpful flow-chart as general guidance for the management of this condition. (2020-07-27)

Formidable duo: Protective effect of CD9 and CD81 in COPD and accelerated aging
Chronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, but the mechanism remains unclear. Osaka University-centered researchers studied the aging-like phenotype and its underlying mechanisms in a COPD mouse model. Double deletion of tetraspanins CD9 and CD81 in epithelial cells downregulated expression of the protein SIRT. As SIRT1 is a key molecule that protects against various lifestyle-related diseases and aging, these tetraspanins may serve as novel therapeutic targets for COPD and aging (2018-04-16)

Study reveals disparities in osteoporosis treatment by sex and race/ethnicity
New research indicates that elderly men are significantly undertreated for osteoporosis compared with elderly women, and blacks have the lowest treatment rates among racial/ethnic groups. The findings are published in the Journal of Pharmaceutical Health Services Research. (2019-03-06)

New osteoporosis treatment uses traditional Chinese herb to prevent bone loss
An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects. Using a compound derived from red sage, UBC researchers have found a way to selectively block an enzyme called Cathepsin K (CatK), which plays a major role in the breakdown of collagen in bones during osteoporosis. (2017-08-29)

Quest for better treatment for effects of menopause
During menopause, lack of oestrogens increases the risk of suffering cardiovascular diseases. For her doctoral thesis, University of the Basque Country researcher, Ainhoa Ruiz del Agua, studied the effects of substitute treatments and the genetic factors influencing the response to these therapies. (2008-05-28)

Risk for aging-related diseases elevated among thyroid cancer survivors
Risk for aging-related diseases such as heart disease and diabetes was significantly higher among thyroid cancer survivors in Utah than it was among age-matched, cancer-free individuals, with those diagnosed before age 40 having the highest risk for some of the diseases. (2017-11-22)

Under-reporting of vertebral fractures by radiologists: A missed opportunity
A new retrospective study by researchers at the University of Oxford has found that within a cohort of hip fracture patients many had previous imaging studies showing incidental vertebral fractures -- but 54 percent of the vertebral fractures were not reported by radiologists. The study puts a spotlight on the under-reporting of osteoporotic vertebral fractures, particularly by radiologists who are not specialized in musculoskeletal imaging. This is a missed opportunity to prevent subsequent, often life-threatening hip fractures. (2017-09-08)

Physical therapy cuts urine leaks dramatically for women with osteoporosis
After menopause, women with osteoporosis struggle more with urinary incontinence than women with healthy bones do. But physical therapy that includes pelvic floor muscle training can produce dramatic improvements, shows a study published online today in Menopause, the journal of The North American Menopause Society. The study is the first-ever randomized, controlled trial of physical therapy for these urinary troubles in postmenopausal women with osteoporosis or low bone mass. (2016-02-17)

UAB-led study shows drug effectiveness in reducing glucocorticoid-induced bone loss
About one in every 100 people in the world takes glucocorticoids long term to treat immune-mediated diseases. However, glucocorticoids, such as prednisone, have a side effect -- they induce glucocorticoid-induced bone loss, causing an estimated yearly bone fracture rate of 5 percent. An alternative treatment option to the standard treatment now appears promising, according to an international study. Researchers compared the monoclonal antibody denosumab against a standard bisphosphonate. (2018-04-27)

Small molecule plays big role in weaker bones as we age
With age, expression of a small molecule that can silence others goes way up while a key signaling molecule that helps stem cells make healthy bone goes down, scientists report. (2018-09-18)

Too much of a good thing? High doses of vitamin D can lead to kidney failure
A case study in CMAJ highlights the dangers of taking too much vitamin D. (2019-04-08)

Study: Low-weight, high-repetition exercise increases bone density up to 8 percent in adults
A new research study published today in The Journal of Sports Medicine and Physical Fitness finds that low-weight, high-repetition resistance training increases bone mineral density in adults, challenging assumptions that heavy weight-training is required to build bone mineral density. Participants who completed the study experienced up to 8 percent bone mineral density increases in the legs, pelvis, arms and spine. (2015-10-26)

Women who discontinue bisphosphonates for two years or more have higher hip fracture risk
Women who took a drug holiday (temporary or permanent discontinuation of a medicine) from using bisphosphonates for more than two years have a significantly higher risk of a hip fracture compared to others who continued their treatment, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego. (2017-11-04)

What's new in the field of microbiota and bone health?
These invited reviews, published in Calcified Tissue International by experts in the field, provide a comprehensive overview of the latest knowledge and research developments related to the gut-musculoskeletal axis. (2018-02-20)

Fringe benefits: Drug side effects could treat human hair loss
A new drug could ease the distress of men and women who suffer from baldness, according to researchers from the University of Manchester's Centre for Dermatology Research. The study from the laboratory of Professor Ralf Paus, is published today in the open-access journal PLOS Biology (2018-05-08)

Outwitting the 'silent thief' of osteoporosis
In a world first, new Australian research has revealed that genetic profiling can help predict whether an individual will break a bone through osteoporosis. The findings, which arise from Australia's globally recognized Dubbo Osteoporosis Epidemiology Study, are likely to contribute to clinical decision-making in future, bringing us one step closer to personalized medicine for bone disease. (2016-10-13)

FRAX intervention and assessment thresholds for seven Latin American countries
Newly published Fracture Risk Assessment Tool (FRAX®) -based intervention thresholds for the following seven Latin American countries represent a substantial advance in the detection of individuals at high risk of fracture: Argentina, Brazil, Colombia, Chile, Ecuador, Mexico and Venezuela. (2018-01-22)

Study: Absence of key protein, TTP, rapidly turns young bones old
The absence of TTP, a protein critical to the control of inflammation, may lead to rapid and severe bone loss, according to a new study led by the University at Buffalo. (2018-03-09)

IOF announces Tetra Pak's support of World Osteoporosis Day
The International Osteoporosis Foundation announced today that Tetra Pak, one of the world's leading food processing and packaging companies, will be a major partner for the IOF during 2006 in promoting awareness of how individuals can build strong bones and contribute to their bone health. Tetra Pak will also be a key partner in the World Osteoporosis Day (WOD) activities. (2006-04-05)

Race, ethnicity influence fracture risk in people with diabetes
Caucasians and Hispanics with diabetes have a greater risk of fracture compared to those without diabetes, while African Americans with diabetes have little to no additional fracture risk, according to a study to be presented Saturday, March 23 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La. (2019-03-23)

LED-based UV irradiation safely prevents the loss of bone and muscle mass in mice
A research team at Nagoya University has revealed that narrow-range ultraviolet (UV) irradiation using light emitting diodes (LEDs) safely increases serum vitamin D levels in aging mice and thereby prevents the loss of their bone and muscle mass. (2020-10-01)

Survival Better For Kidney Recipients Taken Off Steroids
Weaning kidney transplant recipients off steroids is associated with excellent patient and graft survival, according to a University of Pittsburgh study being presented at the American Society of Transplant Physicians meeting May 11. The study also foud the incidence of rejection was much lower in the patients who no longer took the steroids. (1997-05-09)

Medication prevents osteoporosis in men treated for prostate cancer
One of the fastest-growing osteoporosis risk groups consists of men with prostate cancer who receive androgen-deprivation therapy to lower testosterone levels. In the Sept. 27 issue of New England Journal of Medicine, researchers from the Massachusetts General Hospital describe how the drug pamidronate prevented bone loss in prostate cancer patients treated with what are called GnRH agonists. (2001-09-26)

Holocaust survivors had higher rates of chronic conditions, lower rates of death
Holocaust survivors had higher rates of chronic conditions but lower rates of death than a comparison group of individuals insured by the same healthcare services organization in Israel. Biological and psychosocial reasons that may help to explain the findings need more study but researchers suggest unique characteristics of resilience among Holocaust survivors and better health literacy may be among the possibilities. (2019-01-04)

Potential new target for reducing osteoporosis risk in men
Researchers have identified a new regulator of vitamin D metabolism that could be targeted to reduce the risk of osteoporosis in men undergoing prostate cancer therapy, according to a study published in the Journal of Molecular Endocrinology. This study has identified a previously unknown link between male sex hormone levels and vitamin D that may have future therapeutic value for treating related deficiencies of the vitamin. (2018-01-30)

Exercise may improve kidney function in obesity, reduce risk of renal disease
Aerobic exercise may reduce the risk of diabetes-related kidney disease in some people, according to a new study. The findings are published ahead of print in the American Journal of Physiology -- Renal Physiology and was chosen as an APSselect article for December. (2018-12-04)

New material will allow abandoning bone marrow transplantation
Scientists from the National University of Science and Technology 'MISIS' developed nanomaterial, which will be able to restore the internal structure of bones damaged due to osteoporosis and osteomyelitis. A special bioactive coating of the material helped to increase the rate of division of bone cells by three times. In the future, it can allow to abandon bone marrow transplantation and patients will no longer need to wait for suitable donor material. An article about the development was published in Applied Surface Science. (2019-03-19)

New strategy against osteoporosis
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health. (2020-08-05)

Sooner on your feet after hip fracture
An already available drug can help patients get back on their feet more rapidly after a hip fracture, according to an international study published in the Journal of Bone Joint Surgery. The results suggest that treatment with the drug accelerates the healing process in broken bones. (2016-11-21)

New opportunities for detecting osteoporosis
Osteoporosis can be detected through low dose computed tomography (LDCT) imaging tests performed for lung cancer screening or other purposes. A study published in the Journal of Bone and Mineral Research found that such tests can identify large numbers of adults with low bone mineral density. (2020-11-04)

Participating in sports during childhood may have long-term benefits for bone health
Participation in organized sport during childhood and adolescence is associated with bone mass at 20 years of age, according to a Journal of Bone and Mineral Research study. (2018-10-17)

History of broken bones overlooked when treating osteoporosis
Women who need treatment for osteoporosis -- thinning of the bones -- may not be receiving it because their history of fractures is not being considered by physicians, according to a study done in part at the University of Alberta. (2005-02-24)

Full bone mass restored to most postmenopausal women with osteoporosis in two-year trial of new treatment
The first fully controlled two-year study of a new treatment for osteoporosis in postmenopausal women restored bone mass to its original level in nearly two thirds of the women participating in the trial, UC San Francisco scientists reported today. (1999-06-16)

Studies in men reveal higher chance of secondary fractures, value of bone strengthening exercises
Two new studies released this week shine a spotlight on men's bone health which is often overshadowed by the focus on osteoporosis and fracture risk in women. The findings are being presented at the American Society for Bone and Mineral Research (ASBMR) 2018 Annual Meeting in Montréal, the premier scientific meeting in the world on bone, mineral and musculoskeletal science. (2018-09-30)

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