Popular Osteoporosis News and Current Events | Page 24

Popular Osteoporosis News and Current Events, Osteoporosis News Articles.
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Clinical usefulness of bone turnover marker concentrations in osteoporosis
A new IFCC-IOF review finds lack of comparability between current clinical assays for CTX is evident, indicating possible limitations of combining such data for meta-analyses; to improve interpretation of patient results harmonization of units for reporting serum/plasma CTX (ng/L) and PINP (μg/L) is recommended. Further study of the relationships between clinical assays for CTX and PINP and physiological and pre-analytical factors contributing to variability in BTM concentrations is required. (2016-08-02)

UCLA researcher discovers epigenetic links in cell-fate decisions of adult stem cells
The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases, especially osteoporosis. Now, UCLA School of Dentistry professor and leading cancer scientist Dr. Cun-Yu Wang and his research team have made a significant breakthrough in that direction. The scientists have discovered two key epigenetic regulating genes that govern the cell-fate determination of human bone marrow stem cells. (2012-07-06)

Professor Cyrus Cooper awarded the Heberden Medal of the British Society for Rheumatology
Professor Cyrus Cooper, Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit, University of Southampton, has been awarded the Heberden Medal of the British Society for Rheumatology. The award recognizes his outstanding research on the epidemiology, pathophysiology and prevention of osteoporosis. (2011-05-12)

Poor bone health may start early in people with multiple sclerosis
Osteoporosis and low bone density are common in people in the early stages of multiple sclerosis (MS), according to a new study published in the July 12, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology. (2011-07-11)

IOF Committee of National Societies Medal awarded to Dr. Elias Hanna Saba
Dr. Elias Hanna Saba, Chief Executive Director of the Palestinian Osteoporosis Prevention Society, was awarded the International Osteoporosis Foundation's Committee of National Societies Medal during the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases. (2016-04-17)

Vitamin D gets an A+ for treating heart disease
Women over age 65 who took vitamin D had nearly one-third less risk of dying from heart disease as women who did not take the supplements, according to research presented today at the American Heart Association's Asia Pacific Scientific Forum meeting today. (2002-04-23)

Improving early detection and management of mitochondrial disease
The Canadian Inherited Metabolic Diseases Research Network launches first-ever study of clinical practice for mitochondrial disease. (2015-09-21)

UAB study reveals bone coupling factor key to skeletal health
Previously, scientists had searched for but missed the biological link between bone growth and bone remodeling -- a natural give-and-take system that is crucial to skeletal health. A new study in Nature Medicine pinpoints the coupling factor as transforming growth factor beta-1, or TGF beta-1. (2009-07-07)

Rare mutation causes early heart disease and metabolic syndrome
Yale School of Medicine researchers have identified a rare defect in a single gene that poses a substantial risk for metabolic syndrome and early heart disease, the leading cause of death worldwide. (2007-03-01)

Are teen binge drinkers risking future osteoporosis?
Binge-drinking teenagers may be putting themselves at risk for future osteoporosis and bone fractures. (2010-07-13)

Wrist fracture significantly raises risk of hip fracture
A new study presented today at the IOF Regionals 4th Asia-Pacific Osteoporosis Meeting in Hong Kong showed that patients with Colles' fracture are at higher risk than patients with osteoporosis to have a subsequent hip fracture within one year; Colles' fracture and osteoporosis together further increase the risk of hip fracture. (2013-12-13)

After a fracture, it's time to rethink medications
Gerontologists at Beth Israel Deaconess Medical Center and Hebrew SeniorLife Institute for Aging Research underscore the importance of reviewing patients' prescription medications in the wake of a fracture. Appearing alongside original research by Munson et al that finds few changes are made to patients' prescription medications in the four months following a fracture, the commentary is a call for clinicians to coordinate care among orthopedics, rehabilitation services and primary care to reevaluate patients' medication use. (2016-08-22)

IOF position paper reveals enormous variation in worldwide usage of FRAX
Doctors worldwide now use tools such as FRAX, a widely available online calculator, to help identify patients in need of osteoporosis treatment. A new position paper by the IOF Epidemiology and Quality of Life Working Group has assessed the uptake of FRAX worldwide. The study concludes that there were approximately 2.3 million FRAX calculations during a one-year period beginning in May 2012, with enormous variation in worldwide usage. (2014-01-27)

Researchers urge monitoring of bone health during chemotherapy
In laboratory tests on mice, researchers found that a medication often used to reduce toxic side effects of chemotherapy induced bone loss and helped tumors grow in bone. So the researchers at Washington University School of Medicine in St. Louis are recommending increased awareness of bone health during cancer treatments. (2007-01-11)

Benefits of osteoporosis treatments outweigh possible risk of rare femoral fractures
The occurrence of an unusual type of fracture of the femur, or the thigh bone, is very low in patients with osteoporosis, including those treated with the drug family known as bisphosphonates, according to a new study led by a team of UCSF epidemiologists. (2010-03-24)

Alternative to hormone replacement therapy shows promising results
A study conducted in monkeys has found new evidence that tibolone, a steroid commonly prescribed in Europe as an alternative to hormone replacement therapy, is a promising treatment for osteoporosis and has no adverse artery effects, report scientists from Wake Forest University Baptist Medical Center in this month's Journal of Clinical Endocrinology and Metabolism. (2001-11-06)

World's largest meeting dedicated to osteoporosis and osteoarthritis opens in Rome
The world's largest congress dedicated to the epidemiology, pathogenesis, prevention, and treatment of osteoporosis and osteoarthritis has opened today in Rome, Italy with 4,500 delegates. The European Congress on Osteoporosis & Osteoarthritis, which continues until April 20th at the Rome Cavalieri, is jointly organized by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the International Osteoporosis Foundation. (2013-04-17)

Follicle-stimulating hormone may affect bone loss in menopausal women
New research suggests that hormone, follicle-stimulating hormone may be involved in decreasing bone mineral density during menopause. (2010-04-25)

New lung health research presented at CHEST 2009
New research presented at CHEST 2009 highlights lung health abstracts related to the link between osteoporosis and bronchiectasis, calculating the (2009-11-04)

Infant bone growth and maternal vitamin D levels during pregnancy influence future fracture risk
New research shows that bones vulnerability to osteoporosis and fractures depends on how the bones developed during pregnancy and childhood. (2006-06-04)

ESCEO-AMGEN Osteoporosis Fellowships awarded in Florence
Four ESCEO-AMGEN Osteoporosis Fellowships, each valued at $50,000, were awarded to young researchers working in Belgium, Canada, UK and Switzerland. (2010-05-06)

Getting down to specifics: Blocking one RANK function inhibits bone loss
A new report describes the development of a cell-permeable inhibitor that specifically blocks the contribution of the protein RANK to the formation and function of the cells responsible for breaking down bone. Importantly, this drug protected against bone loss in two mouse models of diseases associated with bone destruction, leading to the suggestion that this approach might be beneficial to individuals with diseases such as osteoporosis. (2009-03-02)

Researchers discover underlying mechanisms of skin hardening syndromes
Researchers from Boston University School of Medicine (BUSM) have discovered new details about the underlying mechanisms of skin hardening syndromes. The team connected pharmacological properties of the Novartis Pharma AG drug called balicatib to the skin disorder for the first time after investigating adverse reactions suffered by patients participating in a clinical trial for the treatment of osteoporosis. These findings appear online in the Journal of the American Academy of Dermatology. (2011-05-17)

Caffeine intake increases the rate of bone loss in elderly women
In a study published in the American Journal of Clinical Nutrition, Rapuri et al. compared the bone mineral density of women in high and low categories of caffeine consumption to examine the interaction between caffeine intake, genetic type, and osteoporosis. (2001-10-23)

Link between widely used osteoporosis drugs and heart problems probed
New research at Wake Forest University School of Medicine evaluated the link between a common class of drugs used to prevent bone fractures in osteoporosis patients and the development of irregular heartbeat. (2009-04-06)

Global study reveals differences in standard of care for osteoporosis across the world
In a first-of-its-kind study in osteoporosis, one in four women surveyed from Europe, North America, and Australia reported having one or more bone fractures since the age of 45 years. (2008-05-27)

Mayo Clinic study finds definitive evidence relating to the role of estrogen in elderly males
A Mayo Clinic study, published in the December edition of the Journal of Clinical Investigation, provides new evidence that estrogen is dominant in the regulation of bone resorption in elderly men. Based on the study conclusions, men also need to be concerned about the long-term effects of bone loss, or osteoporosis. (2000-12-12)

No bones about it: Eating dried plums helps prevent fractures and osteoporosis
When it comes to improving bone health in postmenopausal women -- and people of all ages, actually -- a Florida State University researcher has found a simple, proactive solution to help prevent fractures and osteoporosis: eating dried plums. (2011-08-17)

CRI scientists discover new bone-forming growth factor that reverses osteoporosis in mice
A team of scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) discovered a new bone-forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has implications for regenerative medicine. (2016-12-13)

Steroid injection linked to increased risk of bone fractures
Patients treated with an epidural steroid injection for back pain relief are at increased risk of bone fractures in the spine, according to a Henry Ford Hospital study. Researchers say the risk of fracture increased 29 percent with each steroid injection, a finding they believe raises patient safety concerns. (2012-10-25)

Epilepsy drugs cause bone loss
Epilepsy drugs can increase the rate of bone loss in older women, according to a study published in the June 8 issue of Neurology, the scientific journal of the American Academy of Neurology. Women over age 65 who were taking drugs for epilepsy were losing bone mass at nearly twice the rate of women who were not taking epilepsy drugs. (2004-06-07)

BMPs and bone loss: Get it through your noggin
A study in the September 15 issue of the Journal of Clinical Investigation, by Etsuko Abe and colleagues at Mount Sinai School of Medicine in New York has revealed that the balance between the expression of the bone-building protein BMP, and the BMP inhibitor noggin, plays a crucial role in regulating bone formation and loss. The study suggests that recombinant BMP, recently approved by the FDA, may prove useful in reversing age-related bone loss. (2003-09-15)

UCLA-led team may have found key to cause of Cushing disease
UCLA researchers and their colleagues have found that testicular orphan nuclear receptor 4 (TR4) is overexpressed in pituitary tumors that spark the excess production of adrenocorticotrophic hormone (ACTH). The scientists discovered that by knocking down TR4 in lab mice, they were able to reverse tumor growth and excess ACTH production. (2013-05-30)

New evaluation of osteoporosis therapies
New evaluation of osteoporosis therapies finds gastrointestinal-related cost differences. Actonel patients had fewer gastrointestinal-related medical visits than Fosamax patients. (2003-05-15)

Estrogen With Or Without Progestin Reduces Dangerous Form Of Cholesterol, PEPI Investigators Report
New findings from a large-scale study of estrogen replacement therapy help show why the treatment may help reduce a woman's risk of a heart attack. Results from the Postmenopausal Estrogen/Progestin Intervention study show estrogen replacement therapy, with or without progestin, produces consistent and sustained reductions in plasma lipoprotein (a) concentrations. (1998-03-17)

Gluten-free diet reduces bone problems in children with celiac disease
Celiac disease (CD) is an inherited intestinal disorder characterized by life-long intolerance to the ingestion of gluten, a protein found in wheat, rye, and barley. Although CD can be diagnosed at any age, it commonly occurs during early childhood. Reduced bone mineral density is often found in individuals with CD. A new article in the journal Nutrition Reviews examines the literature on the topic and reveals that a gluten-free diet can affect children's recovery. (2009-10-08)

Doctors develop new measures for bone disease
As we age we can expect to shrink an average of three to four centimeters. Such loss is normal due to shrinkage of the disks within the spine. However, researchers at the University of Alberta have developed a guide to help doctors determine when height loss is a normal part of aging, and when it is likely due to something else -- usually osteoporosis. (2006-02-17)

UB scientists discover role of melatonin in bone formation
University at Buffalo researchers have shown for the first time that melatonin, a hormone produced naturally by the pineal gland and used widely as a supplement to diminish jet lag and improve sleep patterns, may play an important role in promoting bone growth. (1999-09-20)

400 never-before published findings to be presented at pharmacology conference
The nation's leading pharmacologists and researchers on the impact of drugs on the body will gather from March 6-10 at the annual meeting of the American Society for Clinical Pharmacology and Therapeutics (ASCPT). (2001-02-07)

FDA-approved drugs eliminate, prevent cervical cancer in mice
Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis. (2009-11-09)

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