Popular Ovarian Cancer News and Current Events

Popular Ovarian Cancer News and Current Events, Ovarian Cancer News Articles.
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Eight of 10 people with cancer risk genes don't know it
Genomic screening of more than 50,000 people shows that more than 80 percent of those who carry an identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer don't know it despite frequent interaction with the healthcare system. (2018-09-21)

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment. (2018-10-05)

Study shows new treatment pathway to prevent and treat endometrial cancer recurrence
In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. (2021-02-23)

Mayo discovery means individualized ovarian, brain cancer therapies
Mayo Clinic researchers have discovered that a molecular communication pathway -- thought to be defective in cancer -- is a key player in determining the effectiveness of measles virus oncolytic cancer treatment in ovarian and aggressive brain cancers. This discovery enabled researchers to develop an algorithm to predict treatment effectiveness in individual patients. The findings appear in the Journal of the National Cancer Institute. (2018-05-16)

Complex cellular machine visualized to yield new insights in cancer
Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein machine, elucidating how the RSC complex works and what role it has in healthy and cancer cells. (2019-10-31)

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan. (2018-07-10)

Distinguishing fatal prostate cancer from 'manageable' cancer now possible
Scientists at the University of York have found a way of distinguishing between fatal prostate cancer and manageable cancer, which could reduce unnecessary surgeries and radiotherapy. (2018-10-18)

NUS scientists combine antimalarial drug with light sensitive molecules for promising treatment of cancer
NUS scientists discovered that a combination of artemisinin, which is a potent anti-malarial drug, and aminolaevulinic acid, which is a photosensitizer, could kill colorectal cancer cells and suppress tumor growth more effectively than administering artemisinin alone. This novel combination therapy could also have fewer side effects. (2017-09-18)

Maintenance therapy with rucaparib shows clinical responses in a subgroup of patient with pancreatic cancer
Maintenance treatment with the PARP inhibitor rucaparib (Rubraca) was well tolerated and provided clinical responses among patients with advanced BRCA- or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, according to results from an interim analysis of an ongoing phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)

Metabolite that promotes cancer cell transformation and colorectal cancer spread identified
Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread. The finding highlights the value of targeting D-2HG to establish new therapeutic approaches against colorectal cancer. (2016-12-01)

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells. (2019-04-04)

US Preventive Services Task Force recommendation statement on behavioral counseling to prevent skin cancer
The US Preventive Services Task Force (USPSTF) recommends behavioral counseling to help reduce the risk of skin cancer from ultraviolet (UV) radiation in persons ages 6 months to 24 years with fair skin types. (2018-03-20)

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill. (2020-06-10)

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications. (2020-10-22)

UH Cancer Center researchers develop algorithm to find precise cancer treatments
University of Hawai'i Cancer Center researchers developed a computational algorithm to analyze 'Big Data' obtained from tumor samples to better understand and treat cancer. (2016-08-09)

Lung transplant patients face elevated lung cancer risk
In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients. (2018-12-19)

Prognostic role of elevated mir-24-3p in breast cancer
Using nanostring and RNA-sequencing technologies researchers from the NYU School of Medicine, the Perlmutter Cancer Center, UT MD Anderson Cancer Center, and the University of Massachusetts Medical School identified mi R-24-3p as a potential novel marker of breast cancer metastases in breast cancer. (2018-03-01)

Breast cancer statistics, 2017
Breast cancer death rates dropped 39 percent between 1989 and 2015, averting 322,600 breast cancer deaths during those 26 years. Death rates in several states are now statistically equivalent, perhaps reflecting an elimination of disparities in those states. (2017-10-03)

Huntington's disease provides new cancer weapon
Patients with Huntington's disease, a fatal genetic illness that causes the breakdown of nerve cells in the brain, have up to 80 percent less cancer than the general population. Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer, a new study reports. (2018-02-12)

Many women diagnosed with cancer have sexual health concerns
A new review published in the European Journal of Cancer Care indicates that, in women diagnosed with cancer, concerns pertaining to sexual health are diverse, multiple, and pervade all types and stages of cancer. (2017-08-11)

Engineering a new cancer detection tool
E. coli may have potentially harmful effects but scientists in Australia have discovered this bacterium produces a toxin which binds to an unusual sugar that is part of carbohydrate structures present on cells not usually produced by healthy cells. This structure is a known tumor antigen leading scientists to develop a new cancer detection tool. (2017-06-07)

Avoiding obesity and maintaining stable weight both important in preventing several obesity-related cancers in women
Avoiding obesity as well as maintaining a stable weight in middle adulthood could help prevent certain cancers in women, according to new research presented at this year's European Conference on Obesity (ECO) in Vienna, Austria (May 23-26). (2018-05-23)

The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: A large study from a single institution
Upcoming publication from the British Journal of Cancer, investigating HER2 expression as a predictor of recurrence and development in patients with DCIS. (2019-05-07)

Androgen receptor targeted imaging of prostate cancer as future modality for diagnosis
Future direction in prostate cancer imaging involves the development of androgen receptor based imaging using nonsteroidal antiandrogen agent for early diagnosis of prostate cancer. (2017-10-06)

Hitgen and Cancer Research UK's Manchester Institute enter license agreement in lung cancer
Cancer Research UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer. (2017-02-27)

Type 2 diabetes associated with risk of aggressive breast cancer in black women
African American women with type 2 diabetes (often referred to as adult-onset diabetes) are at a greater risk for developing breast cancer. (2017-11-15)

Measuring the effects of drugs on cancer cells
A new approach established at the University of Zurich sheds light on the effects of anti-cancer drugs and the defense mechanisms of cancer cells. The method makes it possible to quickly test various drugs and treatment combinations at the cellular level. (2018-07-11)

Inherent feminizing effect of germ cells: New insights into sex determination
Germ cells have long been recognized as the only cells that can transfer genetic materials to the next generation via the sperm or egg. However, recent analyses in medaka (teleost fish) revealed another essential role of germ cells -- feminizing the gonads. Researchers showed the feminizing effect of germ cells occurs in parallel with other reproductive elements. Germ cells in medaka may have a potential to feminize gonads at the moment they have developed. (2018-03-29)

Can our genes help predict how women respond to ovarian cancer treatment?
New research, led by Professor Anna deFazio from the Westmead Institute and Westmead Hospital, has shown that the genes we inherit can have a significant impact on how the body processes chemotherapy drugs, which may lead to different clinical outcomes for ovarian cancer patients. (2018-02-15)

Scientists have identified the presence of cancer-suppressing cells in pancreatic cancer
Researchers have identified cells containing a protein called Meflin that has a role in restraining the progression of pancreatic cancer. They have also shown that cancer progression can be controlled by artificially increasing the amount of this protein in the cells. These findings could lead to the development of new therapies against pancreatic cancer. (2019-10-07)

Prostate cancer discovery may make it easier to kill cancer cells
A newly discovered connection between two common prostate cancer treatments may soon make prostate cancer cells easier to destroy. Drugs that could capitalize on the discovery are already in the pipeline. (2015-12-17)

Molecular 'magnets' could improve cancer immunotherapy
Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients, according to new research published in Cell. Scientists at the Francis Crick Institute have discovered that immune cells called Natural Killer cells accumulate in tumours and release chemicals that attract specialised dendritic cells (cDC1) - white blood cells known for triggering anti-cancer immune responses - to the tumour. (2018-02-08)

CNIO researchers confirm links between aggressive prostate cancer and hereditary breast cancer
The study has potential implications for families with members suffering from these types of tumours who are at an increased risk of developing cancer. The finding is based on PROREPAIR-B, a prospective multi-centre observational cohort study that followed up more than 400 patients with metastatic prostate cancer, aimed to identify genetic markers associated with its progression and treatment response. Further studies will evaluate whether patients with BRCA2 mutations can undergo treatments used in patients with ovarian and breast cancer. (2019-01-09)

New understanding of why cancer cells move
A University of Hawai'i Cancer Center researcher has identified how some cancer cells are made to move during metastasis. The research provides a better understanding of how cancer spreads and may create new opportunities for cancer drug development. (2017-12-27)

Protein analysis may reveal new cancer treatment targets
Researchers have used lab technology called mass spectrometry to study the proteins expressed by human cancer cells. (2018-06-15)

Advanced therapy offers cure for relapsed cancer patient
Testicular cancer patients who do not respond to traditional therapy can be cured with high-dose chemotherapy and a stem cell transplant, according to an Indiana University School of Medicine study by Lawrence Einhorn, M.D.; Stephen Williams, M.D.; Rafat Abonour, M.D., and colleagues published in the July 26 issue of the New England Journal of Medicine. Although the number of relapsed testicular cancer patients in the US is small, the IU Simon Cancer Center treats a majority of them. (2007-07-25)

Scientists track ovarian cancers to site of origin: Fallopian tubes
Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus. Now, results of a study of nine women suggest that the genomic roots of many ovarian tumors may indeed arise in the fallopian tubes, potentially providing insights into the origin of ovarian cancer and suggesting new ways for prevention and intervention of this disease (2017-10-23)

ECOG-ACRIN discovers a simple blood test may predict recurrence of breast cancer
Late recurrence five+ years after surgery accounts for at least half of all breast cancer recurrences. There are no tests that identify who is at highest risk. ECOG-ACRIN Cancer Research Group researchers studied a blood test for circulating tumor cells, finding that in women cancer-free five after diagnosis, 5% had a positive test, which was associated with a 35% recurrence risk after two years, compared with only 2% with a negative test. Findings require follow-up. (2017-12-08)

Researchers find link between breast cancer and two gene mutations
Individuals with Lynch syndrome, a genetic condition that has long been known to carry dramatically increased risk of colorectal cancer and uterine cancer, now also have an increased risk of breast cancer. This is the conclusion of a study in the journal Genetics in Medicine which is published by Springer Nature. (2018-01-19)

Blood test shows potential for early detection of lung cancer
A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests. (2018-06-02)

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