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Popular Pathology News and Current Events, Pathology News Articles.
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Gene expression patterns may help determine time of death
International team of scientists led by Roderic Guigó at the Centre for Genomic Regulation (CRG) in Barcelona shows that changes in gene expression in different tissues can be used to predict the time of death of individuals. (2018-02-13)
Traumatic brain injury biomarker shows promise to support rapid damage evaluation and predict outcomes
A new study in The American Journal of Pathology found that a brain lipid molecule, lysophosphatidic acid (LPA), was significantly increased after traumatic brain injury (TBI) in a preclinical animal model. (2018-07-16)
Using computers to detect breast cancer
Jeffrey Golden, MD, comments on new research exploring the use of computer algorithms in detecting the spread of breast cancer to lymph nodes. (2017-12-12)
Linking heart attack damage to the spleen and kidney, an integrated study of heart failure
Ganesh Halade, who uses a mouse heart attack model to research ways to prevent heart failure, has published a functional and structural compendium of the simultaneous changes taking place in the heart, spleen and kidneys in mice during the period of acute heart failure immediately following a heart attack and during the longer period of chronic heart failure that comes next. (2017-11-15)
Blood stored longer may be less safe for patients with massive blood loss and shock
In a collaborative study using a mouse model, researchers have found mechanistic links between older stored red blood cell transfusions and subsequent bacterial pneumonia. (2018-03-09)
Findings show potential use of artificial intelligence in detecting spread of breast cancer
Computer algorithms detected the spread of cancer to lymph nodes in women with breast cancer as well as or better than pathologists. (2017-12-12)
University of Leicester announces world first forensic technique
A team led by a University of Leicester forensic pathologist is believed to be the first in the world to use a new radiological approach for mass fatality investigation. (2006-02-24)
Blood vessels also affected by Alzheimer's disease
A research conducted by the UAB demonstrates that mice suffering from this disease also have substantial malfunctions in small blood vessels, important in nourishing different organs and tissues and in regulating blood pressure, and which mainly affects females. (2018-03-16)
Expert panel issues new guidelines for lung cancer molecular testing
Guidelines add ROS1 to list of tests matching lung cancer with targeted treatments, among other updated recommendations. (2018-01-30)
Scientists reverse aging-associated skin wrinkles and hair loss in a mouse model
Researchers have reversed wrinkled skin and hair loss, hallmarks of aging, in a mouse model. (2018-07-20)
Researchers describe mechanism that underlies age-associated bone loss
A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. (2017-09-22)
Harnessing the power of genomic sequencing augments diagnosis and treatment of lymphoid cancer
A new study published in The Journal of Molecular Diagnostics has established that hybrid-capture sequencing is the method of choice for sequencing 'actionable' gene mutations across the most common forms of lymphoid cancer. (2018-02-08)
Thyroid cancer discovery points to new treatments, prevention
The actions of a mutated protein in cells linked to thyroid cancer have been uncovered by researchers at Queen's University. (2006-11-15)
Millions of novel genetic variants found in 1000 Swedish individuals
An extensive exercise to map genetic variation in Sweden has found 33 million genetic variants, 10 million of which are novel. (2017-08-25)
Microscope using UV instead of visible light emerging as diagnostic tool
New MUSE technology obtains high-resolution images of fresh biopsies for analysis within minutes, eliminating need for conventional slides and preserving original tissue sample. (2017-12-04)
Sensitive new assay finds abnormalities in tumor cells that other techniques may miss
RNA-Seq, a new next-generation assay, can detect gene fusions in solid tumor cells with high accuracy and excellent reproducibility. (2018-06-18)
How liver cancer develops
Researchers at the University of Zurich and the University Hospital Zurich have discovered a major mechanism in the development of liver cancer. (2017-09-11)
New Pathology Atlas maps genes in cancer to accelerate progress in personalized medicine
A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. (2017-08-17)
Family doctors could better detect child neglect with increased dental health training
New research now suggests that GPs lack the awareness and training to identify dental neglect in children, and therefore could miss the opportunity to share potential cases of wider abuse or neglect to other health and welfare professionals. (2018-05-10)
Inflammation drives progression of Alzheimer's
According to a study by scientists of the DZNE and the University of Bonn now published in the journal (2017-12-20)
Active young adults with Type 1 diabetes have muscle complications
A new study from McMaster and York universities in Canada has found that poor muscle health may be a complication of Type 1 diabetes, even among active twenty-somethings. (2018-04-18)
Follicular lymphoma: A tale of 2 cancers
Many people survive well beyond 10 years following diagnosis of follicular lymphoma. (2016-12-13)
New tool for prognosis and choice of therapy for rheumatoid arthritis
In rheumatoid arthritis, antibodies are formed that affect the inflammation in the joints. (2017-03-23)
Alternative splicing is crucial to muscle mass maintenance
Alternative splicing plays a crucial role in maintaining adult muscle mass, which has implications in aging and chronic disease. (2018-07-10)
Testing the accuracy of FDA-approved and lab-developed cancer genetics tests
Amid the debate about how much these tests should be regulated by the FDA, one question has gone unanswered: how well do LDTs and FDA-CDs perform? (2017-12-14)
Amyloid protein transmission through neurosurgery
Amyloid beta pathology -- protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new UCL-led study. (2018-02-15)
AMP Iissues consensus guideline recommendations for NGS bioinformatics pipelines
The Association for Molecular Pathology, the premier global, non-profit molecular diagnostics professional society, today published 17 consensus recommendations to help clinical laboratory professionals achieve high-quality sequencing results and deliver better patient care. (2017-11-16)
Growing evidence that probiotics are good for your liver
Increased awareness of the importance of the microbes that live in our gut has spurred a great deal of research on the microbiome and fueled a booming probiotics industry. (2018-04-22)
Patients' self-diagnosis of personality disorders not as far off as previously believed
Purdue University researchers think the gap between a psychologists' diagnosis and a patient's self-evaluation might not be as extreme as previously perceived when both are using the same evaluation tools. (2018-06-11)
AMP publishes recommendations for clinical CYP2C19 genotyping allele selection
AMP has published consensus, evidence-based recommendations to aid clinical laboratory professionals when designing and validating clinical CYP2C19 assays, promote standardization of testing across different laboratories and complement existing clinical guidelines. (2018-02-27)
Higher brain glucose levels may mean more severe Alzheimer's
NIA scientists have found a connection between abnormalities in how the brain breaks down glucose and the severity of the signature amyloid plaques and tangles in the brain, as well as the onset of eventual outward symptoms, of Alzheimer's disease. (2017-11-06)
Smart software can diagnose prostate cancer as well as a pathologist
Chinese scientists and clinicians have developed a learning artificial intelligence system which can diagnose and identify cancerous prostate samples as accurately as any pathologist. (2018-03-16)
Cells appearing normal may actually be harbingers of lung cancer
Airways near lung tumors provide clues to the genetics of cancer. (2014-03-07)
Updated guideline for molecular testing and targeted therapies in lung cancer
A panel of leading experts in molecular pathology has issued new recommendations and updates to guidelines for molecular diagnostic testing of patients with lung cancer. (2018-01-23)
UCLA study sheds light on genetic overlap between major psychiatric disorders
Most medical conditions are largely defined by their physical symptoms. (2018-02-08)
Researchers find infectious prions in Creutzfeldt-Jakob disease patient skin
In a Science Translational Medicine study published today, Case Western Reserve University School of Medicine researchers found that CJD patients also harbor infectious prions in their skin, albeit at lower levels. (2017-11-22)
Early changes to synapse gene regulation may cause Alzheimer's disease
TMDU-led Japanese research revealed a role for splicing proteins in the pathology of Alzheimer's disease. (2018-10-12)
Researchers at LSTM take a novel approach to snakebite treatment
Researchers at LSTM's Alistair Reid Venom Research Unit are looking at treatment for snakebite in a completely different way and have shown that it is possible to treat the bite from one snake with antivenom produced from a completely different species that causes the same pathology in humans. (2018-04-19)
New finding will help target MS immune response
Researchers have made another important step in the progress towards being able to block the development of multiple sclerosis and other autoimmune diseases. (2015-10-29)
Newly characterized molecule offers possibilities for novel Alzheimer's treatments
A study by researchers from Brigham and Women's Hospital (BWH), recently published in Acta Neuropathologica, investigated lesser-known molecules involved in tauopathies like Alzheimer's. (2018-08-02)
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