Popular Psoriasis News and Current Events

Popular Psoriasis News and Current Events, Psoriasis News Articles.
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Russian chemists developed a way to synthesize drugs from renewable precursors
The scientists of RUDN University together with their Russian colleagues have developed a new approach to the synthesis of benzofurans from cheap raw materials. Original furans can be produced from wastes of agriculture and wooworking industry, such as sawdust, cobs and other by-products of crop production. The results of the work were described in the article published in Tetrahedron. (2017-11-14)

Skin game
Medical University of Vienna professor Leopold Eckhart and colleagues have performed one of the largest comparative genomic studies to help determine the key molecular and evolutionary origins of mammalian adaptations seen in skin proteins. ''The results of the present study provide important new data on the evolution of keratins that control the mechanical stability of the epidermis, the outermost layer of the skin,'' said Eckhart. (2018-12-13)

Danish-American research presents new ways of developing treatment of chronic inflammation
Researchers from Aarhus University Hospital and Aarhus University in Denmark in collaboration with researchers from Colorado in the United States have found a new way to treat the inflammation involved in chronic diseases such as psoriasis, asthma and HIV. A group of transmitter substances (cytokines) in the immune system, the so-called IL-1 family, has been shown to play an important role in many of these diseases by regulating the body's immune responses. (2019-08-30)

Psoriasis treated with compound derived from immune cells
A compound from the body's own immune cells can treat psoriasis in mice and holds promise for other autoimmune diseases such as multiple sclerosis, according to a new study at Washington University School of Medicine in St. Louis. (2018-04-18)

Ustekinumab Phase 3 data show long-term improvement of chronic plaque psoriasis
One-year data from a second double-blind, placebo-controlled Phase 3 study showed therapy with ustekinumab given every 12 weeks provided sustained, clinically meaningful improvement in the treatment of moderate to severe psoriasis. According to findings presented at the Annual Meeting of the American Academy of Dermatology, 87 percent and 91 percent of patients responding to ustekinumab 45 mg or 95 mg maintenance therapy, respectively, sustained at least a 75 percent improvement in psoriasis through one year. (2008-02-02)

Review examines diversity in dermatology clinical trials
Racial and ethnic groups can be underrepresented in medical research. So what is the makeup of participants in randomized clinical trials of common dermatologic conditions? A review article published online by JAMA Dermatology attempts to answer that question. (2017-01-04)

Having stress-related disorder associated with increased risk of developing autoimmune disease
Stress-related disorders brought on by traumatic or stressful life events were associated with increased risk of developing an autoimmune disease. (2018-06-19)

Inflammation, depression and antidepressant response: Common mechanisms
In findings published electronically in Molecular Psychiatry, researchers from University of Miami found polymorphisms in inflammation-related genes that are associated with susceptibility to major depression and antidepressant response. Two genes critical for T cell function in the immune system have been associated with susceptibility for major depressive disorder and antidepressant treatment response: PSMB4 (proteasome beta 4 subunit) and TBX21 (T-bet). (2008-05-29)

Weight loss reduces psoriasis symptoms
Weight loss has a significant and prolonged positive impact on psoriasis symptoms and quality of life. The findings stem from a study conducted by Herlev and Gentofte Hospital, in collaboration with the University of Copenhagen's Department of Nutrition, Exercise and Sports and other participants. The results are published in The American Journal of Clinical Nutrition, an internationally renowned scientific journal. (2016-12-22)

New findings show Enbrel significantly reduced levels of C-reactive protein
Amgen and Wyeth Pharmaceuticals, a division of Wyeth, today announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein, a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group. These results will be presented today at the American Academy of Dermatology Scientific Meeting in San Antonio, Texas. (2008-02-01)

Insight into potential new strategy to target skin diseases like psorias
Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation. (2018-05-04)

Increased depression, suicidal thoughts and stress are reported in patients with chronically itchy skin
Itch is a very common symptom in patients suffering from skin diseases. In a new multicenter cross-sectional study on the psychological burden of itch in the Journal of Investigative Dermatology, published by Elsevier, investigators report that the presence of itch in dermatological patients was significantly associated with clinical depression, suicidal ideation and stress. They recommend providing patients with access to a multidisciplinary team to prevent and manage problems associated with itch. (2019-10-29)

Cellular stress increases the probability of developing autoimmune diseases
Researchers found that cellular stress enhances the activation of certain type of immune cells with implications in many chronic inflammatory conditions. (2017-06-13)

Phase 3 data show golimumab improved psoriatic arthritis symptoms
Patients with active psoriatic arthritis receiving monthly subcutaneous injections of golimumab experienced significant and sustained improvements in the joint and skin manifestations of the disease, according to findings from the largest phase 3 biologic study ever completed in subjects with psoriatic arthritis. (2007-11-07)

Psoriasis medication may improve heart disease in patients with the skin condition
Anti-inflammatory biologic drugs used to treat severe psoriasis have the potential to prevent heart disease in patients with the skin condition, according to research published today in Cardiovascular Research, a journal of the European Society of Cardiology (ESC). During one year of treatment, biologic therapy improved coronary artery plaque similar to the effect of a low-dose statin. (2019-02-05)

Racial minorities less likely to see a doctor for psoriasis
Despite the fact that their disease may be more severe, a new study shows minorities are less likely than white Americans to see a doctor for psoriasis treatment. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that black, Asian, and other non-Hispanic minorities are about 40 percent less likely to see a dermatologist for psoriasis than whites. (2017-12-13)

Therapeutic drug monitoring does not improve remission for patients starting infliximab
New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care. (2020-11-06)

Popular alternative therapy for psoriasis performs no better than placebo
Anecdotal evidence touting the healing power of the Indian spice turmeric for psoriasis received a setback in a prospective study published this month by a leading dermatology journal stating that the low response rate of patients who ingested the active ingredient of the exotic spice was probably a result of the placebo effect. (2008-02-29)

Humira does not improve aortic vascular inflammation in psoriasis patients
An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation -- a key marker of future risk of major cardiovascular events -- unlike other antibodies that target different aspects of the immune system. (2018-05-18)

Study links psoriasis treatment and improvement in heart artery disease
Researchers have found that treating psoriasis, a chronic inflammatory skin disease, with biologic drugs that target immune system activity can reduce the early plaque buildup that clogs arteries, restricts blood flow, and leads to heart attacks and stroke. The findings highlight how immunotherapies that treat inflammatory conditions might play a role in the reduction of cardiovascular disease risks. (2019-02-05)

Racial differences uncovered in debilitating itchy skin condition
An international team led by Johns Hopkins Medicine researchers has conducted what is believed to be the largest detailed published study of people with a poorly understood skin condition known as prurigo nodularis (PN). Such studies collect information on a whole subset of people at once and at a particular point in time. (2018-06-14)

TWEAKing inflammation
Superficially, psoriasis and atopic dermatitis may appear similar but their commonalities are only skin deep. Atopic dermatitis, also known as eczema, is primarily driven by an allergic reaction, while psoriasis is considered an autoimmune disease. Nevertheless, researchers at La Jolla Institute for Allergy and Immunology were able to pinpoint a common driver of skin inflammation in both diseases. (2017-05-22)

Right beneath the skin we all have the same bacteria
In the dermis skin layer, the same bacteria are found across age and gender. This has been shown by researchers from the University of Copenhagen in a new study which has studied skin samples from knees and hips. The researchers hope it is a step in the direction of a better understanding of why skin disorders occur. (2020-02-12)

Fire ant venom compounds may lead to skin treatments
Solenopsins, the main toxic components of fire ant venom, chemically resemble ceramides, which are lipid-like molecules essential for maintaining for the barrier function of the skin. Solenopsin analogs can reduce skin thickening and inflammation in a mouse model of psoriasis, Emory and Case Western scientists have shown. (2017-09-11)

Psoriasis linked with need for cardiovascular interventions in patients with hypertension
Psoriasis is linked with increased risks of hypertension and cardiovascular disease, but its effect on the course of cardiovascular disease remains unknown. (2018-10-17)

Higher weight increases risk of psoriasis
The higher a person's BMI, the greater the chance of getting psoriasis. But researchers are still uncertain as to why. (2019-04-26)

Drug that treats psoriasis also reduces aortic vascular inflammation
An antibody used to treat the skin disease psoriasis is also effective at reducing aortic inflammation, a key marker of future risk of major cardiovascular events. (2018-02-16)

Link between autoimmune, heart disease explained in mice
Autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis more than double the risk of cardiovascular disease. A new study shows that immune cells that arise during autoimmune disease cause cholesterol to become trapped inside blood vessels. (2018-11-08)

Psoriasis and psychiatric illnesses: What are the links?
A new review examines the potential link between psoriasis and mental health conditions. (2017-08-11)

Could treating psoriasis in the future be as easy as going online?
New research from the Keck School of Medicine of USC finds that an online care delivery model is equivalent to in-person care for improving psoriasis symptoms. (2018-10-05)

Psoriasis onset determines if psoriatic arthritis patients develop arthritis or psoriasis first
In a new study presented at the 2019 ACR/ARP Annual Meeting, researchers found the age of psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis. Additionally, they found that pustular psoriasis is associated with arthritis onset two years earlier than the intercept interval; and there is an increased delay for nail involvement, plaque psoriasis or family history of psoriasis from psoriasis to arthritis by approximately two years for each characteristic. (2019-11-09)

Handheld scanner reveals vascularization in psoriasis patients
A newly developed tissue scanner allows looking under the skin of psoriasis patients. This provides clinically relevant information, such as the structure of skin layers and blood vessels, without the need for contrast agents or radiation exposure. A team of researchers from Helmholtz Zentrum München and the Technical University of Munich (TUM) recently introduced the technology in Nature Biomedical Engineering. (2017-05-31)

Preventing psoriasis with vanillin
Small amounts of artificial vanilla extract, also known as vanillin, are in a wide range of products, from baked goods to perfumes. But vanillin's versatility doesn't stop there. In a recent mouse study reported in ACS' Journal of Agricultural and Food Chemistry, researchers report that this compound could also prevent or reduce psoriatic skin inflammation. (2017-11-29)

'Master regulator' of skin formation discovered
Researchers at Oregon State University have found one gene in the human body that appears to be a master regulator for skin development, in research that could help address everything from skin diseases such as eczema or psoriasis to the wrinkling of skin as people age. (2009-03-24)

Why thick skin develops on our palms and soles, and its links to cancer
Scientists from Queen Mary University of London have discovered that foot callouses/keratoderma (thickened skin) can be linked to cancer of the esophagus (gullet), a disease which affects more than 8,000 people in the UK each year. (2017-02-01)

How was Mediterranean diet associated with severity of psoriasis?
Adherence to a Mediterranean diet, an eating plan filled with fruits and vegetables, legumes, cereals, bread, fish, fruit, nuts and extra-virgin olive oil, may be associated with the severity of the skin condition psoriasis. (2018-07-25)

New insight into the mechanism of the drug against sclerosis and psoriasis
A multidisciplinary research team at Aarhus University has provided fundamental new insight into the mechanism of the medical drug dimethyl fumarate, which is the active component of important treatments for multiple sclerosis and psoriasis. The results contribute to the development of new strategies for drug discovery. (2018-10-31)

Insights into psoriasis suggest a new treatment target
Investigators from Brigham and Women's Hospital and the Harvard Stem Cell Institute have uncovered a novel pathway that may explain why skin thickens in psoriasis and suggests new strategies for developing therapies for the condition. (2019-12-11)

Treatment has no sufficient effect in 1 of 5 psoriasis patients
A substantial part of people, one in five, undergoing systemic treatment for psoriasis (i.e. pills taken orally, injections or infusions) still have considerable problems with their disease. This is according to a study with 2,646 Swedish psoriasis patients conducted by researchers at Umeå University and the Swedish Institute for Health Economics, and recently published in the Journal of Dermatological Treatment. (2017-02-02)

A protein that controls inflammation
A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis. They discovered how the protein A20 prevents inflammation and autoimmunity, not through its enzymatic activities as has been proposed, but through a non-enzymatic mechanism. (2020-03-17)

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