Popular SARS News and Current Events

Popular SARS News and Current Events, SARS News Articles.
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Researchers reveal genetic predisposition to severe COVID-19
HSE University researchers have become the first in the world to discover genetic predisposition to severe COVID-19. The results of the study were published in the journal Frontiers in Immunology. http://doi.org/10.3389/fimmu.2021.641900 (2021-02-23)

B cells continue to work against SARS-CoV-2 months after infection, but do not recognize mutant
A new analysis of B cells and more than 1,000 different monoclonal antibodies from 8 patients with COVID-19 shows that, contrary to previous hypotheses, protective B cell responses to the SARS-CoV-2 spike protein remain stable and continue to evolve over a 5-month period, many months after the initial period of active viral replication. (2021-02-23)

Innate immune system worsens the situation in severe COVID-19
In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients. This is shown in an Uppsala University study published in the journal Frontiers in Immunology. (2021-02-23)

University of Minnesota researchers develop two new rapid COVID-19 diagnostic tests
University of Minnesota Medical School researchers have developed two new rapid diagnostic tests for COVID-19 - one to detect COVID-19 variants and one to help differentiate with other illnesses that have COVID-19-like symptoms. (2021-02-23)

Tool encoded in coronaviruses provides a potential target for COVID-19
Coronaviruses exploit our cells so they can make copies of themselves inside us. (2021-02-23)

The mental health impact of pandemics for front line health care staff
New research shows the impact that pandemics have on the mental health of front-line health care staff. Researchers investigated how treating patients in past pandemics such as SARS and MERS affected the mental health of front-line staff. They found that over a third experienced anxiety or depression, almost a quarter experienced PTSD. The team hope that their work will help highlight the impact that the Covid-19 pandemic could be having on the mental health of doctors and nurses worldwide. (2020-10-16)

Effect of high-dose zinc, ascorbic acid supplementation vs usual care on symptom length, reduction among ambulatory patients with SARS-CoV-2 infection
These findings suggest that treatment with zinc, ascorbic acid or both doesn't affect SARS-CoV-2 symptoms. (2021-02-12)

NIH study uncovers blood vessel damage & inflammation in COVID-19 patients' brains but no infection
In an in-depth study of how COVID-19 affects a patient's brain, National Institutes of Health researchers consistently spotted hallmarks of damage caused by thinning and leaky brain blood vessels in tissue samples from patients who died shortly after contracting the disease. In addition, they saw no signs of SARS-CoV-2 in the tissue samples, suggesting the damage was not caused by a direct viral attack on the brain. (2020-12-30)

COVID-19 unmasked: math model suggests optimal treatment strategies
For older patients with COVID-19 infections, the clot-preventing drug heparin and immunity-enhancing drugs may improve outcomes. Patients with conditions such as obesity, diabetes and high blood pressure may benefit from anti-inflammatory drugs and drugs used to control blood pressure and vascular resistance. (2021-01-05)

New coronavirus emerges from bats in China, devastates young swine
A newly identified coronavirus that killed nearly 25,000 piglets in 2016-17 in China emerged from horseshoe bats near the origin of the severe acute respiratory syndrome coronavirus (SARS-CoV), which emerged in 2002 in the same bat species. The new virus, called swine acute diarrhea syndrome coronavirus (SADS-CoV), doesn't appear to infect people, unlike SARS-CoV. The NIAID-funded work was a collaboration among scientists from EcoHealth Alliance, Duke-NUS Medical School, Wuhan Institute of Virology and other organizations. (2018-04-04)

Smoking associated with increased risk of COVID-19 symptoms
Smoking is associated with an increased risk of COVID-19 symptoms and smokers are more likely to attend hospital than non-smokers, a study has found. (2021-01-06)

The Lancet Child & Adolescent Health: First Europe-wide study of children confirms COVID-19 predominately causes mild disease in children and fatalities are very rare
Children with COVID-19 generally experience a mild disease and fatalities are very rare, according to a study of 582 patients from across Europe published today in The Lancet Child & Adolescent Health journal. (2020-06-25)

Study reveals strategy to create COVID-19 drugs to inhibit virus's entry and replication
A new study offers insight into designing antiviral drugs against COVID-19 by showing that some existing compounds can inhibit both the main protease (Mpro), a key viral protein required for SARS-CoV-2 replication inside human cells, and the lysosomal protease cathepsin L, a human protein important for viral entry into host cells. (2020-11-06)

Re-engineering antibodies for COVID-19
Catholic University of America researcher uses 'in silico' analysis to fast-track passive immunity (2020-07-30)

Viruses can evolve in parallel in related species
Viruses are more likely to evolve in similar ways in related species -- raising the risk that they will 'jump' from one species to another, new research shows. (2018-04-12)

December issue SLAS Technology features 'advances in technology to address COVID-19'
The December issue of SLAS Technology is a special collection featuring the cover article, ''Advances in Technology to Address COVID-19'' by editors Edward Kai-Hua Chow, Ph.D., (National University of Singapore), Pak Kin Wong, Ph.D., (The Pennsylvania State University, PA, USA) and Xianting Ding, Ph.D., (Shanghai Jiao Tong University, Shanghai, China). (2020-11-17)

Study of social contact patterns in Hong Kong will give insight into spread of epidemic
The first ever long-term study of patterns of social contact in Hong Kong will improve our knowledge of the growth of epidemics. Hong Kong was where SARS emerged in 2002-2003. The study looked at the number and type of social encounters made by 1,450 residents. This is affected by age but 'supermixers' are not necessarily more likely to contract or spread disease. (2018-02-01)

Math shows how human behavior spreads infectious diseases
Mathematics can help public health workers better understand and influence human behaviors that lead to the spread of infectious disease, according to a study from the University of Waterloo. (2018-08-16)

If healthy people are purposefully infected with COVID-19 for the sake of science, they should be paid
Multidisciplinary team of international experts suggests participants should receive a ''substantial'' amount, be paid ethically. (2021-02-05)

Results of comprehensive SARS-CoV-2 animal model study published in Nature Microbiology
Findings by Texas Biomed and SNPRC scientists support the rhesus macaque as an excellent animal model for vaccine development; suggest baboon as an animal model for drug development. Results provide insight on the complex lung immune response to SARS-CoV-2 infection. Defining animal models has been a critical step in advancing COVID-19 vaccines & therapeutics (2021-01-04)

Battling COVID-19 using UV light
Some University of New Mexico researchers have found a possible breakthrough in how to manage COVID-19, as well as future viruses. It involves using polymer and oligomer materials activated with UV light in order to kill microbes on surfaces. (2020-12-09)

COVID-19 may have consequences for mental health
The COVID-19 pandemic appears to be adversely affecting mental health among hospitalised patients, the healthcare professionals treating them and the general population. This is shown in a new review from the University of Copenhagen that gathers the current knowledge on mental symptoms and mental health during the COVID-19 pandemic. (2020-06-18)

Social distancing may have saved more than 59,000 u.s. Lives if implemented two weeks earlier
Implementing social distancing, business closures, and other non-pharmaceutical interventions (NPIs) in the U.S. two weeks sooner, during the earliest stages of the COVID-19 pandemic, may have (2020-11-06)

Three decades of responding to infectious disease outbreaks
In 1984, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases, testified before Congress showing a world map annotated with a single emerging infectious disease threat, HIV/AIDS. Since then, numerous diseases and pathogens were added, providing a powerful visual reminder of infectious diseases around the globe. In an essay in Annals of Internal Medicine, Dr. Fauci reflects on the efforts to address infectious disease outbreaks of the past three decades. (2017-11-14)

Ultrapotent COVID-19 vaccine candidate designed via computer
An ultrapotent nanoparticle candidate vaccine against COVID-19 has been developed with structure-based vaccine design techniques invented at UW Medicine. It is a self-assembling protein nanoparticle that displays 60 copies of the SARS-CoV-2 Spike protein's receptor-binding domain in a highly immunogenic array. The molecular structure of the vaccine roughly mimics that of a virus, which may account for its enhanced ability to provoke an immune response. (2020-11-02)

COVID-19: Air quality influences the pandemic
An interdisciplinary team from the University of Geneva and the ETH Z├╝rich spin-off Meteodat investigated possible interactions between acutely elevated levels of fine particulate matter and the virulence of the coronavirus disease. Their results suggest that high concentrations of particles less than 2.5 micrometers in size may modulate, or even amplify, the waves of SARS-CoV-2 contamination and explain in part the particular profile of the COVID-19 pandemic. (2020-11-24)

Antibacterial applications of graphene oxides
Graphene oxide (GO) is one of the most widely studied engineered nanomaterials. A review discussed the structure-activity relationships (SARs) involved in GO-induced bacterial killing, the molecular initiating events (MIEs) and biosafety in antibacterial applications (cover articles in Science Bulletin, 2018, 63(2): 133-142). (2018-02-08)

Network theory links behavioral information flow with contained epidemic outbreaks
Over the last two decades, large-scale outbreaks of infectious diseases have resulted in high levels of morbidity, mortality, and overall economic burden for affected regions. As complex networks become increasingly popular tools of study, researchers are applying network theory to the field of epidemiology. In an article in the SIAM Journal on Applied Mathematics, researchers employ a concrete interplay model in quenched multiplex networks to study the connection between adaptive human behavior and epidemic spread. (2018-06-14)

Bats are the major reservoir of coronaviruses worldwide
Results of a five-year study in 20 countries on three continents have found that bats harbor a large diversity of coronaviruses (CoV), the family of viruses that cause severe acute respiratory syndrome coronavirus (SARS) and Middle East respiratory syndrome coronavirus (MERS). PREDICT is a USAID-funded globally coordinated effort to detect and discover viruses of pandemic potential and reduce risk for future epidemics. (2017-06-12)

Ups and downs in COVID-19 data may be caused by data reporting practices
As data accumulates on COVID-19 cases and deaths, researchers have observed patterns of peaks and valleys that repeat on a near-weekly basis. A study published this week in mSystems reports that those oscillations arise from variations in testing practices and data reporting, rather than from societal practices around how people are infected or treated. (2020-07-14)

Neutralizing antibodies in the battle against COVID-19
An important line of defense against SARS-CoV-2 is the formation of neutralizing antibodies. These can eliminate the intruders and have great potential to be used for prevention and treatment of SARS-CoV-2 infection. A team of researchers at the Cologne University Hospital and the German Center for Infection Research (DZIF) has elucidated how these antibodies develop and has isolated potent SARS-CoV-2 neutralizing antibodies. Together with Boehringer Ingelheim, these antibodies are currently being further characterized and developed. (2020-07-08)

Robots as tools and partners in rehabilitation
Why trust should play a crucial part in the development of intelligent machines for medical therapies. (2018-08-17)

Aging-US: 'From Causes of Aging to Death from COVID-19' by Mikhail V. Blagosklonny
Aging-US recently published ''From Causes of Aging to Death from COVID-19'' by Blagosklonny et al. which reported that COVID-19 is not deadly early in life, but mortality increases exponentially with age - which is the strongest predictor of mortality. (2020-10-05)

Pre-existing coronavirus antibodies could help protect children against new pandemic strain
Researchers at the Francis Crick Institute and University College London have found that some antibodies, created by the immune system during infection with common cold coronaviruses, can also target SARS-CoV-2 and may confer a degree of protection against the new viral strain. (2020-11-06)

Lab-made virus mimics COVID-19 virus
Researchers at Washington University School of Medicine in St. Louis have created a virus in the lab that infects cells and interacts with antibodies just like the COVID-19 virus, but lacks the ability to cause severe disease. This safer virus makes it possible for scientists who do not have access to high-level biosafety facilities to join the effort to find drugs or vaccines for COVID-19. (2020-07-21)

New pig virus found to be a potential threat to humans
A recently identified pig virus can readily find its way into laboratory-cultured cells of people and other species, a discovery that raises concerns about the potential for outbreaks that threaten human and animal health. (2018-05-14)

Pain relief caused by SARS-CoV-2 infection may help explain COVID-19 spread
New research shows SARS-CoV-2 promotes pain relief when it infects cells through a common protein receptor, neuropilin-1. The finding gives scientists a novel target for non-opioid pain therapeutics, while also offering an explanation for the unrelenting spread of COVID-19. (2020-10-01)

Broad spectrum antiviral drug inhibits a range of emerging coronaviruses
Researchers have long known that RNA viruses called coronaviruses cause the common cold and pneumonia. In the last two decades or so, though, researchers have found that these viruses can jump between animal and human hosts. In recent years, coronaviruses have caused lethal outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) that span multiple continents. To date, no retroviral drug has been approved to treat these infections. (2018-03-06)

X-ray experiments zero in on COVID-19 antibodies
An antibody derived from a SARS survivor in 2003 appears to effectively neutralize the coronavirus that causes COVID-19, opening the door for speedy development of a targeted treatment. (2020-05-19)

Identifying markers of COVID-19 infection using blood tests
This study identifies the values for six biochemical biomarkers that indicate a patient may be infected with SARS-COV-2 (COVID-19). The key novelty of this study lies in the fact that it was carried out using a blood test and can provide a determination in about 60 minutes. (2020-12-04)

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