Popular Side Effects News and Current Events

Popular Side Effects News and Current Events, Side Effects News Articles.
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Nature hits rewind
The study of evolution is revealing new complexities, showing how the traits most beneficial to the fitness of individual plants and animals are not always the ones we see in nature. Instead, new research by McMaster behavioural scientists shows that in certain cases evolution works in the opposite direction, reversing individual improvements to benefit related members of the same group. (2019-03-19)

Targeted delivery of highly toxic anti-cancer drug to brain tumors
University of Houston biomedical researcher Sheeren Majd is reporting the development and testing of a new nano-carrier as a potential treatment to deliver highly toxic medicine to glioblastomas, the most common and aggressive form of primary brain tumors. (2021-02-23)

Improving drone performance in headwinds
Stability of unmanned aerial vehicles in heavy winds can be improved through rotor placement and angle, according to a team from Tohoku University and Kanazawa Institute of Technology. (2018-02-08)

New study demonstrates significant and sustained improvements in BPH symptoms with AVODART ™
New clinical study findings showed that men with symptoms of benign prostatic hyperplasia (BPH), also known as enlarged prostate, taking AVODART for four years had sustained, long-term improvement in three major markers of BPH -- urinary symptoms, urinary flow rates and prostate volume reduction. AVODART is the first and only dual 5alpha-reductase (5AR) inhibitor approved for the treatment of BPH. (2004-04-14)

'Body on a chip' could improve drug evaluation
MIT engineers have developed new technology that could be used to evaluate new drugs and detect possible side effects before they are approved for human use. Using a microfluidic chip that connects tissue samples from up to 10 organs, the researchers can accurately replicate human organ interactions, allowing them to measure the effects of drugs on different parts of the body. (2018-03-14)

For patients with prostate cancer, dysfunction due to treatment side effects results in increased emotional distress -- and vice versa
A new study published in The Journal of Urology reports that men with prostate cancer who had worse urinary, bowel, and sexual function after surgery or radiotherapy than others experienced more emotional distress. Interestingly, the reverse was also true as experiencing more distress led to worse function. The likelihood of this reciprocal relationship highlights the importance of greater investment in psychosocial care to mitigate treatment side effects in prostate cancer survivors. (2018-05-31)

University of Minnesota research discovers inhibitor to reverse toxic DUX4 effects
New University of Minnesota Medical School research identifies an inhibitor that protects cells from toxic effects associated with facioscapulohumeral muscular dystrophy in cells and mice. (2019-09-11)

Half the amount of chemo prevents testicular cancer from coming back, new trial shows
Testicular cancer can be prevented from coming back using half the amount of chemotherapy that is currently used, a new clinical trial has shown. The new trial showed that giving men one cycle of chemotherapy was as effective at preventing men's testicular cancer from coming back as the two cycles used as standard. (2020-01-02)

Tuberculosis drugs work better with vitamin C
Studies in mice and in tissue cultures suggest that giving vitamin C with tuberculosis drugs could reduce the unusually long time it takes these drugs to eradicate this pathogen. The research is published in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology. (2018-01-03)

Can chocolate, tea, coffee and zinc help make you more healthy?
Ageing and a low life expectancy are caused, at least partly, by oxidative stress. A team of researchers led by Prof. Dr. Ivana Ivanovi-Burmazovi from the Chair of Bioinorganic Chemistry at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), together with researchers from the USA, have discovered that zinc can activate an organic molecule, helping to protect against oxidative stress. (2018-11-02)

New study on the placebo effect and antidepressants in children and adolescents
Although the clinical efficacy of antidepressants in children and adolescents is proven, it is frequently accompanied by side effects. In addition, the influence of the placebo effect on the efficacy of antidepressants is unclear. A meta-analysis of data from over 6,500 patients has now shown that, although antidepressants are more effective than placebos, the difference is minor and varies according to the type of mental disorder. (2017-09-15)

New method identifies which asthma patients respond to systemic corticosteroids
Physicians will be able to predict which of their patients with severe asthma are likely to benefit from treatment with systemic corticosteroids -- and which might only suffer their side effects -- with help from a dozen clinical variables researchers have identified using machine learning techniques, say researchers at Carnegie Mellon University and the University of Pittsburgh School of Medicine. (2019-02-20)

Studies suggest inflammatory cytokines are associated with depression and psychosis, and that anti-cytokine treatment can reduce depression symptoms
Studies presented at this year's International Early Psychosis Association meeting in Milan, Italy, (Oct. 20-22) suggest that increased levels of inflammatory cytokines are associated with increased rates of depression and psychosis, and that treatment to reduce cytokine levels can reduce symptoms of depression. (2016-10-20)

NASA gets a dramatic 3-D view of Typhoon Talim's large eye
NASA created a dramatic 3-D image of powerful Typhoon Talim using data from the Global Precipitation Measurement mission or GPM core satellite. Talim's large eye really made the storm stand out as it moved toward landfall. (2017-09-15)

Nanoparticles deliver anticancer cluster bombs
Scientists have devised a triple-stage 'cluster bomb' system for delivering the chemotherapy drug cisplatin, via tiny nanoparticles designed to break up when they reach a tumor. (2016-03-29)

Giving children a voice in clinical trials
Children as young as 8 years old with incurable cancer can reliably characterize the impact an experimental therapy has on their symptoms and quality of life -- even at the earliest stages of drug development -- making self-reported patient outcomes a potential new clinical trial endpoint. (2017-06-15)

In animal studies, stimulating a brain pathway reduces depressive behavior
Neurobiology researchers have identified a pathway in brain circuitry that, when stimulated, leads to 'antidepressive' behavior in animals. If such brain stimulation proves to have similar effects in people, it may eventually lead to a novel treatment for depression. (2018-04-16)

FDA approves Bystolic, a novel beta blocker
The US Food and Drug Administration has approved Bystolic (nebivolol) for the treatment of hypertension, also known as high blood pressure. Bystolic works differently than many older beta blockers in that it is preferentially beta 1 selective at doses less than or equal to 10 mg, meaning it selectively blocks the effects of adrenaline at the heart. In addition, Bystolic vasodilates -- or widens and expands -- the blood vessels. (2007-12-18)

Study results offer another boon for PARP inhibitors in treatment of advanced breast cancer
Patients with certain advanced hereditary breast cancers may have new treatments options on the horizon, according to two studies presented this week at the annual San Antonio Breast Cancer Symposium. Susan Domchek, M.D., executive director of the Basser Center for BRCA at Penn's Abramson Cancer Center, will present new results from the Mediola and OlympiAD trials showing continued success of treating BRCA-related metastatic breast cancer with the PARP inhibitor olaparib with limited side effects for patients. (2017-12-08)

Researchers find a promising new approach for treating liver cirrhosis
In a study in The American Journal of Pathology, investigators report that treatment with aleglitazar, a dual peroxisome proliferator-activated receptor-alpha/gamma (PPARα/γ) agonist, reduced inflammation, vasoconstriction, angiogenesis, mucosal disruption, and tumor necrosis factor (TNF)-α overproduction in cirrhotic rats with PH. This suggests a promising new approach for treating liver cirrhosis. (2018-06-18)

Anabolic steroids linked to higher rates of premature death in men
Men who use androgenic anabolic steroids -- such as testosterone -- may face a higher risk of early death and of experiencing more hospital admissions, according to a new Journal of Internal Medicine study. (2018-11-21)

Herbal products may compromise prescription drugs and cause serious side effects
An analysis of published studies and reports indicates that a number of herbal products may affect the properties of prescription drugs, leading to alterations in the drugs' effectiveness as well as potentially dangerous side effects. (2018-01-24)

Smoking study personalizes treatment
A simple blood test is allowing Vanderbilt University Medical Center (VUMC) researchers to determine which patients should be prescribed varenicline (Chantix) to stop smoking and which patients could do just as well, and avoid side effects, by using a nicotine patch. (2017-11-20)

Synthetic cannabis ('spice', 'k2') use may boost stroke risk in young users
Synthetic cannabis, also popularly known as 'spice' or 'k2,' may boost the risk of a stroke in young users, warn US doctors writing in the journal BMJ Case Reports. (2018-06-07)

Radiation therapy algorithm could reduce side effects, maintain effect against tumors
A mathematical model for computing radiation therapy treatments could substantially reduce patient side effects while delivering the same results as conventional radiation therapy. (2018-01-05)

Anti-alcoholism drug shows promise in animal models
Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink. (2018-05-03)

Video tags reveal surprising details of blue whale feeding behavior
The lunge feeding of blue whales is an extraordinary biomechanical event in which the largest animal on Earth accelerates and opens its mouth under water, expanding its enormous throat pouch to engulf a huge volume of water, then filtering out its prey. A new study of blue whale feeding strategies reveals surprising preferences with respect to how much and which direction they roll during lunge feeding in order to maximize efficiency. (2017-11-20)

UV laser photolyses to enhance diamond growth
Researchers at the University of Nebraska-Lincoln, USA, reported on a new laser-enabled synthesis route to explore the advantages of laser photochemistry in practical material synthesis in a recent article in Light: Science & Applications. In this work, it is demonstrated that UV laser photolysis of hydrocarbon species altered the flame chemistry to promote the diamond growth rate and film quality. The authors found that the UV laser photolysis plays a key role in suppressing the formation of the side products, nondiamond carbons. (2018-01-25)

New drug makes weight loss safer
Dr. Nir Barak of TAU has adapted a well-known drug used to treat vertigo for a new purpose: to treat obesity without dangerous side effects. (2007-09-26)

New research on the brain's backup motor systems could open door to novel stroke therapies
New research published in the Journal of Physiology could open the door to new therapies to improve the movement of arms and hands of stroke survivors. (2018-02-14)

Study casts doubt on ketamine nasal sprays for depression
Researchers from UNSW Sydney and the Black Dog Institute have questioned the efficacy and safety of intranasal ketamine for depression, with their pilot trial stopped early due to poor side effects in patients. (2018-03-16)

Researchers discover that female cats are more likely to be right-handed
Researchers at Queen's University Belfast have found that female cats are much more likely to use their right paw than males. (2018-01-22)

UV light improving chances of fighting cancer
Scientists at Newcastle University have developed a cancer fighting technology which uses UV light to activate antibodies which very specifically attack tumours. (2007-10-30)

Higher-dose RT lowers risk of recurrence but does not improve survival for men with prostate cancer
Results of a recent NRG Oncology study, NRG Oncology/RTOG 0126, show that high-dose radiotherapy did not improve survival for men with intermediate-risk prostate cancer but did improve biochemical control and rates of distant metastases, when compared to standard radiotherapy. Men who received higher-dose radiotherapy underwent fewer salvage therapies to control tumors that had grown larger or had spread to another body site; however, they also experienced more side effects than did men on the standard radiotherapy treatment arm. (2018-03-23)

Chemical peels are safe for people with darker skin, result in few side effects and complications
Results from a new study led by Boston Medical Center (BMC) indicate that, when performed appropriately, chemical peels can be a safe treatment option for people with darker skin. (2018-03-16)

Improved treatment for alcohol use disorders, chronic pain, mood disorders
A Purdue University team is making drug discoveries to support millions around the world dealing with alcohol use disorders, chronic pain and mood disorders. They discovered that two peptides -- which are naturally metabolic products of Rubisco, a large protein found in many plants like spinach -- may aid in the development of new medications. (2019-01-03)

Viral gene therapy could improve results from breast reconstruction after cancer treatment
A new treatment helps healthy tissue protect itself from radiotherapy damage. Viral therapy reduced damage to skin and underlying tissues in rats -- and improved their outcomes from treatment. A new type of gene therapy delivered using a virus could protect healthy tissues from the harmful side-effects of radiotherapy after cancer treatment, a new study reports. In the future, the treatment could be used to improve outcomes for breast reconstruction surgery in women with breast cancer. (2018-01-24)

Artificial intelligence helps Stanford researchers predict drug combinations' side effects
Millions of people take upwards of five medications a day, but testing the side effects of such combinations is impractical. Now, Stanford computer scientists have figured out how to predict side effects using artificial intelligence. (2018-07-10)

Completing the drug design jigsaw
A powerful new way of analysing how drugs interact with molecules in the body could aid the design of better treatments with fewer side-effects. (2017-10-05)

New drug seeks receptors in sarcoma cells, attacks tumors in animal trials
A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. The researchers conducted a multi-year, cross-disciplinary study that went from screening potential drug candidates to identifying and synthesizing one compound, to packaging it into nanoparticles for delivery in cells, to testing it in cell cultures and finally in mice and pigs with sarcoma tumors. (2018-12-13)

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