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Boron nitride nanofilms for protection from bacterial and fungal infections
NUST MISIS material scientists have presented antibacterial nano-coatings based on boron nitride, which are highly effective against microbial pathogens (up to 99.99%). They can become a safe alternative to the usual antibiotics in implantology since they do not have typical negative side effects. The results of the work are published in the international scientific journal ACS Applied Materials & Interfaces. (2020-10-20)

COVID-19 vaccine creates incentive to improve our health
While we wait for our turn to get vaccinated against SARS-CoV-2, we could - and probably should - use the time to make sure we bring our healthiest emotional and physical selves to the treatment, a new review of previous research suggests. (2021-01-13)

NSAIDs may be more effective than paracetamol for period pain
Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may be more effective for relieving period pain than paracetamol, according to the update of a Cochrane Review. However, it remains unclear whether any one NSAID is safer or more effective than others. (2010-01-19)

UK scientists move closer to creating cartilage from stem cells
Scientists have succeeded in producing cartilage formed from embryonic stem cells that could in future be used to treat the painful joint condition osteoarthritis. (2015-03-03)

UCLA researchers uncover mechanism by which melanoma drug accelerates secondary skin cancers
Researchers at UCLA's Jonsson Comprehensive Cancer Center, working with investigators from the Institute of Cancer Research in London, Roche and Plexxikon, have elucidated the mechanism by which vemurafenib excels at fighting melanoma but also allows for the development of skin squamous cell carcinomas. (2012-01-18)

Shortened RT schedule benefits low-risk prostate cancer patients
Of the more than 220,000 patients newly diagnosed with prostate cancer in 2015, the vast majority will have had early-stage disease at low risk for recurrence. A clinical trial published online April 4th in the Journal of Clinical Oncology confirms that these patients can be treated with a shortened (or hypofractionated) course of radiotherapy and experience a similar level of cancer control as those treated with a conventional course of radiotherapy. (2016-04-06)

Drug can reduce pain for stroke patients
The drug lamotrigine can reduce the pain that affects some stroke patients, according to a study in the January 23 issue of Neurology, the scientific journal of the American Academy of Neurology. Central post-stroke pain occurs in eight percent of stroke patients and is difficult to treat. The only current treatment, amitriptyline, doesn't work for many patients, and has many side effects. (2001-01-22)

Lifestyle changes effective in protecting against Type II diabetes
Changing to a healthier lifestyle appears to be at least as effective as taking prescription drugs in reducing the risk of developing Type 2 diabetes, says a new BMJ study. Type 2 diabetes is a growing problem -- in England around 1.3 million people have diabetes and around five percent of total NHS resources are used for the care of people with diabetes. (2007-01-19)

Dartmouth researchers create 'green' process to reduce molecular switching waste
Dartmouth researchers have found a solution using visible light to reduce waste produced in chemically activated molecular switches, opening the way for industrial applications of nanotechnology ranging from anti-cancer drug delivery to LCD displays and molecular motors. (2014-12-15)

New drug shows promise for kidney disease
Scientists at UC Santa Barbara have demonstrated in the laboratory that a new drug is effective in treating a very common kidney disease -- although it will be a few years before it becomes available for clinical testing. The findings resulted from a collaboration between UCSB and a biotech firm based in Indiana. The study is published in this week's Journal of the American Society of Nephrology. (2012-08-02)

New Drug Tested at UIC Effectively Treats Narcolepsy
University of Illinois at Chicago researchers and those at 20 other sites have found that a new drug helps narcolepsy patients stay awake without being a stimulant. UIC's Center for Narcolepsy Research participated in a trial of Modafinil, the first new drug treatment to be developed for narcolepsy in 30 years. (1996-07-18)

Solar eruptions could electrify martian moons
Powerful solar eruptions could electrically charge areas of the Martian moon Phobos to hundreds of volts, presenting a complex electrical environment that could possibly affect sensitive electronics carried by future robotic explorers, according to a new NASA study. The study also considered electrical charges that could develop as astronauts transit the surface on potential human missions to Phobos. (2017-10-18)

In one cancer therapy, two halves are safer than a whole
Splitting one type of cancer drug in half and delivering the pieces separately to cancer cells could reduce life-threatening side effects and protect healthy, non-cancerous cells, a new study suggests. (2020-08-24)

Drug for rare disorder shows promise for treating herpes viruses
New research shows that the antiviral activity of the drug -- called phenylbutyrate, or PBA -- was even better when used along with acyclovir, a common HSV-1 treatment. When used in combination, less acyclovir is needed to effectively suppress the virus compared to acyclovir alone -- this is important because acyclovir is also known to have toxic side effects in the kidneys. (2020-12-07)

Researchers develop promising way to find new cancer drugs
The enzymes in human cells known as histone deacetylases, or HDACs, are targets for a handful of anticancer drugs because of their ability to affect gene expression. Now, researchers from the University of Copenhagen have developed a new method to investigate how these enzymes work on a molecular level. This new method can also help identify more precise possible anti-cancer drug candidates at a very high pace. (2021-01-25)

New therapy helps to improve audio and visual perception in stroke patients
Stroke is one of the most common neurological disorders worldwide. Many stroke survivors are left with serious health problems. Some patients, for example, find themselves unable to perceive one side of their body and can have problems seeing, hearing and feeling on that side. A team of neuropsychologists at Saarland University, led by Professor Georg Kerkhoff, has developed a new technique that is helping to restore patients' perception of sounds and images. (2014-03-04)

Quiet that ringing in the brain
Epilepsy and tinnitus are both caused by overly excitable nerve cells. Healthy nerves have a built-in system that slams on the brakes when they get too excited. The 'brakes' are actually potassium channels that regulate nerve signals. A new drug may treat both conditions by selectively opening potassium channels in the brain. (2015-06-23)

Rise in weight-loss drugs prescribed to combat childhood obesity
Thousands of children and adolescents are using anti-obesity drugs that in the UK are only licensed for use by adults. The number of young people receiving prescriptions for these drugs has increased 15-fold since 1999, but most stop using them before they could expect to see any benefit, according to a new study. (2009-09-02)

Antipsychotic drugs stop fatal viral infection in brain cells
Scientists from Brown University and Case Western Reserve University have discovered a way to prevent brain cells from becoming infected by the JC virus, a common bug that can cause progressive multifocal leukoencephalopathy, or PML, a fatal nervous system disorder that strikes AIDS patients and others with suppressed immune systems. Their work, published in Science, reveals a surprising cellular defender: antipyschotic drugs. (2004-11-18)

Training the best treatment for tennis elbow
Training and ergonomic advice are more effective than anti-inflammatory drugs and cortisone injections in treating tennis elbow, and give fewer side effects. This is the conclusion of a thesis presented at the University of Gothenburg, Sweden. (2010-12-20)

Even surgery may not help patients with severe constipation
Current guidelines for treating severe constipation include surgical removal of part of the colon, a procedure called subtotal colectomy. Using national databases of hospital activity in the United States, investigators have discovered that colectomies for constipation nearly tripled over a span of 13 years, from 104 procedures in 1998 to 311 in 2011. (2015-10-05)

The immunotherapy, pembrolizumab, is active against mucosal melanoma tumors
Clinical trials of a new immunotherapy, pembrolizumab, have shown that it prolongs life significantly for patients with bladder cancer and is active against a rare sub-type of melanoma, called mucosal melanoma. The findings were presented in two presentations at the European Cancer Congress 2017. (2017-01-28)

Acceptable consequences of screening for prostate cancer
The negative aspects of screening for prostate cancer may be acceptable, since screening halves mortality from the disease. This is the conclusion of a thesis presented at the University of Gothenburg, Sweden. (2011-01-11)

Is an animal's agility affected by the position of its eyes?
New research from scientists in Liverpool has revealed the relationship between agility and vision in mammals. (2010-02-22)

Popular drugs for common male health problems can affect their sexual health
5a-reductase inhibitors commonly used to treat urinary problems in patients with benign prostatic hyperplasia (BPH) and found in popular medications to treat hair loss, can produce, persistent erectile dysfunction (2011-03-07)

New chemical composition of 'poppers' linked to retinal damage
The new chemical composition of the legal high 'poppers' is linked to retinal damage at the back of the eye, finds a small study published online in the British Journal of Ophthalmology. (2017-04-10)

People willing to trade treatment efficacy for reduced side effects in cancer therapies
When choosing their preferred treatment, people with chronic lymphocytic leukemia place the highest value on medicines that deliver the longest progression-free survival, but are willing to swap some drug efficacy for a reduced risk of serious adverse events according to a study published online in Blood Advances, a Journal of the American Society of Hematology. The study also suggests that factoring out-of-pocket costs into this decision-making process may significantly influence a patient's choice of treatment. (2017-11-21)

New technique reduces side-effects, improves delivery of chemotherapy nanodrugs
Carnegie Mellon University researchers have developed a new method for delivering chemotherapy nanodrugs that increases the drugs' bioavailability and reduces side-effects. Their study, published online in Scientific Reports, shows that administering an FDA-approved nutrition source prior to chemotherapy can reduce the amount of the toxic drugs that settle in the spleen, liver and kidneys. (2017-11-28)

Fiber crossings ahead: Key enzymes affecting nervous system pathway identified
University of Tsukuba researchers found the absence of enzymes key for corticospinal tract guidance, Sulf1 and Sulf2, results in abnormal anatomy of the corticospinal tract and impairments in fine motor function. The corticospinal tract of Sulf1/Sulf2 knockout mice showed abnormal fiber crossing at the pyramidal decussation. As a result, bilateral movement was seen when stimulating only one side of the brain, and mice had impaired fine motor control. (2020-02-05)

Anti-anxiety drugs and sleeping pills linked to risk of death
Anti-anxiety drugs and sleeping pills have been linked to an increased risk of death, according to new research from the University of Warwick. (2014-03-31)

Atomic map of malaria drug gives it new life
Researchers have mapped how the malaria drug mefloquine works, providing a route to make effective alternatives and combat rising drug resistance. (2017-03-13)

CCI-779 shows positive safety profile and potential anti-tumor activity
Novel anticancer therapy CCI-779 targets abnormal cell growth, with a generally mild to moderate side-effect profile, according to new data presented today at the European Society for Medical Oncology (ESMO). Further findings revealing the role of CCI-779's target, the recently discovered mTOR3 pathway, were also presented. (2000-10-12)

Botox: Its not just for wrinkles anymore
Injecting botulinum toxin A, or Botox, into the prostate gland of men with benign prostatic hyperplasia (BPH), a condition commonly referred to as enlarged prostate, eases symptoms and improves quality of life. Thirty-one patients out of 41, or 75.6 percent, experienced a 30 percent improvement in urinary tract symptoms and quality of life. These improvements were seen up to one year in some of the patients. (2006-05-23)

New treatment using inhaled interferon may improve lung function in pulmonary fibrosis
Inhaled interferon-gamma may be an effective treatment for idiopathic pulmonary fibrosis, a chronic and progressive form of lung disease caused by excessive formation of fibrotic, or scar tissue, in the lungs, according to an article published in Journal of Aerosol Medicine and Pulmonary Drug Delivery, a peer-reviewed journal from Mary Ann Liebert, Inc. The article on inhaled interferon-gamma is available free online at the Journal of Aerosol Medicine and Pulmonary Drug Delivery website. (2012-02-29)

An LED-based device for imaging radiation induced skin damage
A noninvasive imaging device tested at UC Irvine's Beckman Laser Institute may help predict skin damage effects from radiation treatment in breast cancer patients. (2017-03-29)

Novel treatment for mesothelioma shows promise for patients
novel treatment for advanced mesothelioma is safe and effective and may improve the quality of life for patients who have few treatment options, according to a research abstract presented during a virtual session of the Society of Interventional Radiology's 2020 Annual Scientific Meeting on June 14. (2020-06-15)

Inform doctors when taking herbs and dietary supplements
Although herbs and dietary supplements appear to have beneficial effects on depression, anxiety, insomnia and memory problems, new research shows that potential side effects exist. Millions of depressed or sleepless patients mix prescription medicines with alternative therapies and many do so without informing their doctors. (1999-09-23)

Prospect for more effective treatment of nerve pain
Trigeminal neuralgia is characterized by sharp, lancinating pain in the teeth or facial area. The standard treatment for this chronic nerve pain can cause burdening side effects. A novel substance inhibits the pain effectively and is well tolerated, as documented by the initial results of an international study involving the Center of Dental Medicine at the University of Zurich. (2017-02-20)

Metal implants may cut chemotherapy side effects, study suggests
Cancer patients could one day experience fewer side effects from chemotherapy following a discovery from University of Edinburgh researchers that opens the door for more targeted treatments. (2014-02-13)

Palonosetron with dexamethasone effective at preventing nausea/vomiting after chemotherapy
Palonosetron is as effective as, and in some ways better than, granisetron in preventing the nausea and vomiting that is often experienced after highly emetogenic chemotherapy, conclude the authors of a phase III comparator trial that is published in an article online first and in the February edition of the Lancet Oncology. (2009-01-07)

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