Popular Statins News and Current Events

Popular Statins News and Current Events, Statins News Articles.
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Astrazeneca urges FDA to dismiss Public Citizen petition on Crestor(R)
In a comprehensive, 30-page response sent today to the U.S. Food and Drug Administration (FDA), AstraZeneca stated that Public Citizen's Health Research Group's (HRG) petition to remove CRESTOR® (rosuvastatin calcium) from the market provides no scientific basis, is inaccurate and must be denied. (2004-07-21)

Late dinner and no breakfast is a killer combination
People who skip breakfast and eat dinner near bedtime have worse outcomes after a heart attack. That's the finding of research published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC). (2019-04-18)

Statins associated with reduced morbidity and mortality in patients with primary sclerosing cholangitischolangi
An award-winning register-based study reports a reduced risk of all-cause mortality, liver transplantation, liver cancer, and variceal bleeding in patients with primary sclerosing cholangitis exposed to statins. (2018-04-12)

Algae extract increases good cholesterol levels, Wayne State research finds
A Wayne State University researcher has found that an extract from algae could become a key to regulating cardiovascular disease. In a study funded by Health Enhancement Products of Bloomfield Hills, Mich., Smiti Gupta, Ph.D., assistant professor in the department of nutrition and food science in the College of Liberal Arts and Sciences, has found that dietary intake of ProAlgaZyme increased the level of high-density lipoprotein (HDL) in an animal model. (2012-07-06)

Herbal products may compromise prescription drugs and cause serious side effects
An analysis of published studies and reports indicates that a number of herbal products may affect the properties of prescription drugs, leading to alterations in the drugs' effectiveness as well as potentially dangerous side effects. (2018-01-24)

Statins have unexpected effect on pool of powerful brain cells
Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells known as glial progenitor cells that are important to brain health as we age, scientists have found. The new findings shed light on a long-debated potential role for statins in the area of dementia. (2008-07-03)

Could statins ease deadly heart condition in rare neuromuscular disease?
Decreased HDL and ApoA-l levels in the general population are associated with an increased risk of death from cardiomyopathy and heart failure. Researchers found the FA patients had serum ApoA-I levels lower than healthy control subjects. In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol-lowering drug increased a precursor of HDL (high-density lipoprotein), the (2018-04-17)

Increasing statins dose and patient adherence could save more lives
Thousands of heart attacks and deaths from cardiovascular disease could be prevented by patients taking higher doses of statins and taking the drugs as advised by doctors. (2018-12-07)

Statins may be associated with reduced mortality in 4 common cancers
A diagnosis of high cholesterol is associated with reduced mortality and improved survival in the four most common cancers, according to research presented today at Frontiers in CardioVascular Biology 2016. The 14-year study from nearly one million patients found that a high cholesterol diagnosis was associated with lower risk of death in lung, breast, prostate and bowel cancers. (2016-07-08)

European guidelines on lipid control advocate 'lower is better' for cholesterol levels
Low-density lipoprotein (LDL) cholesterol levels should be lowered as much as possible to prevent cardiovascular disease, especially in high and very high risk patients. That's one of the main messages of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) Guidelines on dyslipidaemias published online today in European Heart Journal, and on the ESC website. (2019-08-31)

Statins linked to higher diabetes risk
Individuals who take cholesterol-lowering statins may be at higher risk for developing high blood sugar levels, insulin resistance, and eventually type 2 diabetes, according to an analysis published in the British Journal of Clinical Pharmacology. (2019-03-06)

Being in treatment with statins reduces COVID-19 mortality by 22% to 25%
A research by the Universitat Rovira i Virgili (URV) and Pere Virgili Institut (IISPV) led by Lluís Masana has found that people who are being treated with statins have a 22% to 25% lower risk of dying from COVID-19. (2020-11-04)

Statins are more effective for those who follow the Mediterranean diet
For those who have already had a heart attack or a stroke, the combination of statins and Mediterranean Diet appears to be the most effective choice to reduce the risk of mortality, especially from cardiovascular causes. It is the result of an Italian study conducted at the I.R.C.C.S. Neuromed, Pozzilli, Italy on over 1,000 adults recruited in the Moli-sani Study, published in the International Journal of Cardiology. (2018-12-21)

Preliminary research shows noninvasive therapy may reverse atherosclerosis
Injecting microscopic fibers that remove plaque deposits from artery walls reversed atherosclerosis in preliminary research. (2018-05-11)

Many older adults do not take prescribed statins properly
In a British Journal of Clinical Pharmacology study of older adults prescribed statins, first-year nonadherence and discontinuation rates were high. (2018-11-07)

Icosapent ethyl drug reduces risk of recurrent cardiovascular events
Further insights from the REDUCE-IT trial show that high-dose, pure and stable EPA omega 3 drug not only reduces the burden of first cardiovascular events but also subsequent and total heart attacks, strokes, and other measures. (2019-03-18)

Pharmacy closures associated with declines in cardiovascular medication adherence
How pharmacy closures are associated with declines in cardiovascular medication adherence for statins, β-blockers and oral anticoagulants among adults 50 or older was the focus of this analysis of prescription claims. (2019-04-19)

Study shows taking aspirin before or after coronary
New research presented at this year's Euroanaesthesia congress in Copenhagen, Denmark shows that in patients undergoing a coronary artery bypass graft (CABG) surgery, taking aspirin before and after surgery is associated with an 18 percent to 34 percent reduced mortality risk after four years. (2018-06-03)

Use of statins before cardiac arrest may aid survival afterwards
Patients who have been using cholesterol-lowering drugs known as statins fare better after a cardiac arrest than non-users. Among subgroups of patients who use statins preventively, those with Type 2 diabetes see the greatest benefit after a cardiac arrest. (2016-11-12)

Gene study spots clues to heart risk for statin patients
A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol. (2018-05-09)

A possible risk group for statin use
In a study of over 1,000 individuals with coronary artery disease, researchers have found that high levels of an enzyme called PLTP significantly increased the risk of heart attack in the subset of patients taking statins, suggesting that high levels of PLTP in the blood should be a consideration for potential statin treatment. (2009-03-23)

New drug strategy: Target ribosome to halt protein production
Researchers have discovered a drug that acts like a wrench thrown into the ribosome, stopping the protein production machinery, but only for a small number of proteins, upending current thinking that drugs targeting the ribosome would cause it to stop production of all of a cell's proteins. UC Berkeley and Pfizer chemists who teamed up to find out how it works suggest that similar drugs that selectively stall the ribosome could therapeutically target specfic proteins. (2017-03-21)

New sustainable production method could advance plastics and pharmaceuticals
A team of chemical engineers at The University of Texas at Austin has developed a new, cost-effective method for synthetically producing a biorenewable platform chemical called triacetic acid lactone (TAL) that can be used to produce innovative new drugs and sustainable plastics at an industrial scale. (2018-02-12)

A blueprint for better cholesterol-lowering drugs
A better strategy for developing more effective cholesterol- lowering drugs may come from the work of HHMI researchers who have produced the first studies of the structural mechanism by which the widely prescribed statin drugs, such as Lipitor and Zocor, lower cholesterol. (2001-05-10)

Statin add-on may offer new/another option for reducing LDL-C in high-risk patients
Patients at high risk for a heart attack or stroke who took an investigational drug in addition to a statin had significantly lower LDL, or 'bad' cholesterol, after 12 weeks compared to similar patients who took a placebo in addition to statin therapy, according to research presented at the American College of Cardiology's 68th Annual Scientific Session. (2019-03-18)

LJI researchers are one step closer to an effective anti-atherosclerosis vaccine
A new paper published in Circulation by researchers at La Jolla Institute for Allergy and Immunology reports successful vaccination of atherosclerotic mice with a small chunk of protein snipped out of 'bad cholesterol.' Vaccination reduced plaque levels in test mice, and other experiments with human blood samples identified the class of T cells likely responsible for positive outcomes. The paper suggests that a comparable strategy could form the basis of a human vaccine. (2018-04-12)

Statins have low risk of side effects
Cholesterol-lowering statin drugs are associated with a low risk of side effects. The benefits of statin therapy for most people outweigh the risks. (2018-12-10)

Cholesterol byproduct hijacks immune cells, lets breast cancer spread
High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link. A new study by University of Illinois researchers found that the culprit is a byproduct of cholesterol metabolism that acts on specific immune cells so that they facilitate the cancer's spread instead of stopping it. (2017-10-12)

People with heart disease at risk when pharmacies close
New research shows that when pharmacies close, people stop taking widely used heart medications -- like statins, beta-blockers and oral anticoagulants -- that have known cardiovascular and survival benefits. (2019-04-19)

Evidence does not support statin use for conditions other than heart disease
Despite studies suggesting benefits for conditions beyond cardiovascular disease (CVD), the evidence does not support revising current statin prescribing guidelines. Findings from an evidence review and meta-analysis are published in Annals of Internal Medicine. (2018-10-08)

New study shows HIV-infected women not using statins as recommended
A new study has shown that HIV-infected women do not use statins as recommended by the most recent guidelines. (2017-12-08)

Long-lasting adaptations of the innate immune system through the bone marrow
The immune system not only detects and destroys pathogens such as microbes but also plays a role in the onset of diseases such as arteriosclerosis. Scientists from Radboud university medical center, Bonn, Dresden and Pennsylvania, studied a new mechanism that regulates the immune system's functioning. They discovered that cholesterol inhibitors may prevent infections, that a high-fat Western diet can have a long-lasting effect on our immunity and that even our stem cells can be disrupted. (2018-01-11)

Medications to treat cardiovascular risk factors do not impact erectile function
Erectile dysfunction (ED) is a major public health problem. Men being treated for cardiovascular risk factors such as high blood pressure and high cholesterol are at increased risk of developing ED and often consider this condition a side effect of their medications. However, a new study into the effects of cholesterol-lowering statins and blood-pressure lowering candesartan/HCTZ concludes that these medications do not negatively affect erectile function. The study is published in the Canadian Journal of Cardiology. (2018-01-29)

Widely used physical health drugs may help treat serious mental illness
Medications commonly used to combat physical health diseases, such as high blood pressure, could bring significant benefits to people with serious mental illnesses (SMI) such as schizophrenia, bipolar disorder or non-affective psychoses, according to a large cohort study led by UCL. (2019-01-09)

Patients say lack of physician guidance and fear of side effects are why they don't take statins as prescribed
Despite national guidelines indicating that statins can lower risk of heart attack and stroke, many patients who could benefit do not take them. Most of these patients say they were never offered the cholesterol-lowering drugs, or they experienced or were fearful of possible side effects. (2019-03-27)

10 percent of Chinese adults have high heart disease risk, aren't treated for it
Researchers at Yale and at the National Center for Cardiovascular Disease in China just quantified a significant opportunity to improve Chinese heart health: 1 in 10 middle-aged Chinese adults are at high risk for heart disease, yet only about 3 percent of those at-risk are taking either statins or aspirin, the recommended therapies for managing that risk. This study was published in the Annals of Internal Medicine. (2019-02-21)

Statins and colorectal cancer
A large case-control study published in this week's PLOS Medicine conducted by Ronac Mamtani, M.D., MSCE, an assistant professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA, and colleagues provides evidence that indication bias may explain the link between statin use and reduced colorectal cancer risk. (2016-04-26)

Heart attacks increasingly common in young adults
Even though fewer heart attacks are occurring in the US -- in large part due to the use of medications like statins and a decline in smoking -- these events are steadily rising in very young adults. New data not only validate this trend but also reveal that more heart attacks are striking those under age 40, according to research being presented at the American College of Cardiology's 68th Annual Scientific Session. (2019-03-07)

Taking statins for heart disease cuts risk in half, yet only 6 percent of patients taking as directed
Study finds that taking statins for heart disease cuts risk of second serious event in half, yet only 6 percent of patients are following as directed. (2019-03-16)

New vaccine could prevent high cholesterol
A new cholesterol-lowering vaccine leads to reductions in 'bad' LDL cholesterol in mice and macaques, according to research published in Vaccine. The authors of the study, from the University of New Mexico and the National Institutes of health in the United States, say the vaccine has the potential to be a more powerful treatment than statins alone. (2015-11-10)

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