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Popular Transplantation News and Current Events, Transplantation News Articles.
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Comprehensive pediatric CAR T guidelines developed by MD Anderson and PALISI
Almost one year after the US Food and Drug Administration (FDA) approval of chimeric antigen receptor (CAR) T-cell therapy for children with acute lymphoblastic leukemia (ALL), researchers at The University of Texas MD Anderson Cancer Center and the Pediatric Acute Lung Injury and Sepsis Investigators Network (PALISI) today published treatment guidelines for managing the treatment in the online issue of Nature Reviews Clinical Oncology. (2018-08-06)
New technique improves outcome for living donor liver transplants
Thanks to a review paper done at the University of Alberta radiologists at the University of Alberta Hospital are now using CT imaging for living-donor liver transplantation. (2008-03-18)
Practical hair regeneration technology
Researchers have developed a method for the mass preparation of cellular aggregates, also known as 'hair follicle germs (HFGs)', that may lead to a new treatment for hair loss. (2018-02-01)
Improving cell transplantation after spinal cord injury: When, where and how?
Spinal cord injuries are mostly caused by trauma, often incurred in road traffic or sporting incidents, often with devastating and irreversible consequences. (2016-05-31)
Osteochondral allograft transplantation effective for certain knee cartilage repairs
Isolated femoral condyle lesions account for 75 percent of the cartilage repair procedures performed in the knee joint, and physicians have a variety of techniques to consider as part of surgical treatment. (2018-03-10)
Scientists use gene editing to eliminate viruses in live pigs
Scientists have edited the pig genome to deactivate a family of retroviruses. (2017-08-10)
Breakthrough in the production of dopamine neurons for Parkinson's disease
Researchers at Lund University, Sweden, are rapidly moving towards the first ever transplantations of embryonic stem cell derived dopamine neurons in persons with Parkinson's disease. (2016-10-28)
Technology may help increase number of kidneys transplanted
Many deceased donor kidneys are declined for transplantation because of concerns over their quality, but a new BJS (British Journal of Surgery) study found that a technique called normothermic machine perfusion can assess the quality of a kidney and determine its suitability for transplantation. (2017-12-06)
Gut microbiome in digestive health: a new frontier in research
Research on the gut microbiome is one of the most promising areas of science today. (2019-01-04)
Method assesses how well dialysis clinics refer patients for transplantation
A new method is useful for assessing how well individual dialysis facilities are referring patients for kidney transplantation. (2018-01-25)
iPS cell-derived inner ear cells may improve congenital hearing loss
A Japanese research group has successfully grafted human iPS cell-derived inner ear cells that express human-derived proteins into the inner ears of embryonic mice. (2018-02-08)
Retina transplants show promise in patients with retinal degeneration
Preliminary research shows encouraging results with transplantation of retinal cells in patients with blindness caused by retinitis pigmentosa and age-related macular degeneration, according to a report in the August issue of American Journal of Ophthalmology. (2008-07-10)
Cellular barcoding helps scientists understand the behavior of stem cells
By tagging bone marrow cells of mice with a genetic label, or barcode, researchers were able to track and describe the family tree of individual blood cells as they form in their natural environment. (2018-01-03)
Menstrual blood -- a valuable source of multipotential stem cells?
Researchers suggest that stromal cells derived from menstrual blood may represent a potentially unlimited, ethically unencumbered, easily collectable and inexpensive source of stem cells for use in regenerative medicine. (2008-04-23)
Mayo Clinic study finds heart transplant patients benefit from new approach to immunosuppression
A new immunosuppression regimen for heart transplant patients can improve kidney function and prevent transplant coronary artery disease, according to two new Mayo Clinic studies. (2007-04-26)
Study concludes no racial disparities in long-term outcomes in recipients of liver transplants
New research published in the Journal of the American College of Surgeons shows long-term survival and liver rejection rates are equivalent for African-American liver transplant patients as compared with patients of other races. (2008-05-19)
A new tool for improving uterine transplant surgery
Future Science Group (FSG) today announced the publication of an article in Future Science OA demonstrating the first use of multispectral imaging in gynecology, in a uterine transplant setting. (2018-02-12)
Long-term prevention of organ rejection
The Konstanz immunologist Professor Marcus Groettrup and his team have developed a procedure for preventing organ rejection in rats after renal transplantation, and for suppressing the creation of antibodies in the recipients' immune systems. (2017-12-08)
Hearing restoration may be possible with cochlear repair after transplant of human cord blood cells
Hearing loss due to cochlear damage may be repaired by transplanting human umbilical cord hematopoietic stem cells. (2008-09-03)
HCV-related liver transplantation and post-transplant survival rates in Europe have improved rapidly in the era of direct-acting antiviral drugs
HCV-related liver transplantation and post-transplant survival rates in Europe have improved rapidly in the era of direct-acting antiviral drugs. (2018-04-13)
Protective effect of genetically modified cord blood on spinal cord injury in rats
Researchers of Kazan Federal University genetically modified cord blood which managed to increase tissue sparing and numbers of regenerated axons, reduce glial scar formation and promote behavioral recovery when transplanted immediately after a rat contusion spinal cord injury. (2016-04-08)
US study reports dramatic reduction in likelihood of liver transplantation in patients with hepatoce
ILC 2018: Although hepatocellular carcinoma is now the leading indication for liver transplantation in the USA, the probability of patients receiving a transplant has declined significantly in recent years. (2018-04-13)
Alternatives to whole liver transplants for children have become safer, study finds
In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation (WLT), such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly. (2018-02-12)
Effective pediatric cancer treatment is possible in the midst of a refugee crisis
Six years into Lebanon's refugee crisis, St. Jude Children's Research Hospital and the Children's Cancer Center of Lebanon at the American University of Beirut Medical Center offer a blueprint for effective childhood cancer treatment during turmoil. (2018-02-28)
Educational video may increase public willingness to become face transplant donors
After watching a brief educational video, members of the public are more likely to say they would be willing to donate a facial transplant to a severely disfigured patient, reports a study in the January issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). (2018-01-02)
Feinstein Institute study looks at impact of a popular pre-heart transplant therapy on the kidney
Scientists, nephrologists and cardiac surgeons from The Feinstein Institute for Medical Research and Northwell Health's Department of Internal Medicine, Cardiology and Cardio-Thoracic Surgery examined the impact of a popular pre-heart transplant therapy on the kidney in a study published today by The Clinical Journal of the American Society of Nephrology. (2017-10-25)
Curve-eye-ture: How to grow artificial corneas
Research reveals corneal cells grown on curved surfaces arrange themselves in a regular lattice structure giving the artificial cornea strength and transparency like that normally found in the human eye. (2017-10-19)
Racial and ethnic disparities in live donor kidney transplants
Despite efforts over the past two decades to increase the number of black and Hispanic patients receiving kidney transplants from related or unrelated living donors, these racial/ethnic minority patients are still much less likely to undergo such transplants than white patients, Johns Hopkins researchers report. (2018-01-23)
Research shows cord blood comparable to matched bone marrow
University of Minnesota researchers report that umbilical cord blood transplants may offer blood cancer patients better outcomes than bone marrow transplants, according to an analysis of outcome data performed at the Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee. (2007-06-07)
Chinese researchers report first lung stem cell transplantation clinical trial
A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. (2018-02-09)
Researchers develop new technique to model transplantation of the human liver
A novel technology developed by researchers at the Massachusetts General Hospital enables the model-ing of human liver transplantation in an experimental setting. (2017-11-29)
Viagra helps mobilize bone marrow stem cells for transplantation in mice
The combination of two clinically approved drugs -- Viagra and Plerixafor -- rapidly and efficiently mobilizes blood stem cells from the bone marrow into the bloodstream in mice, researchers report Oct. (2019-10-10)
Urinary markers may indicate prognosis after kidney transplantation
A new British Journal of Clinical Pharmacology study indicates that certain markers can help predict which patients may experience problems after receiving an organ transplant. (2017-09-07)
NIH study finds donor corneas can be safely preserved for longer period
Results from a large, national clinical trial show that corneal donor tissue can be safely stored for 11 days without negatively impacting the success of transplantation surgery to restore vision in people with diseases of the cornea. (2017-11-10)
Rutgers researchers advance stem cell therapy with biodegradable scaffold
Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer's and Parkinson's diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries. (2018-11-05)
Does brain tissue regeneration depend on maturity of stem cells used for transplantation?
New research has shown that the success of transplanting stem cells into the brain to regenerate tissue damaged by stroke may depend on the maturity of the neuronal precursor cells used for transplantation. (2017-09-13)
Hepatocellular carcinoma: Resection vs. transplantation
Liver transplantation is the gold standard for treating early hepatocellular cancers. (2017-09-08)
Opioid crisis leads to rise in viable hearts and lungs for those awaiting transplants
A new study published in The New England Journal of Medicine by investigators from Brigham and Women's Hospital and University of Utah, examines survival outcomes for patients who have received organs from donors who died of drug intoxication. (2018-05-16)
Successful implantation of heart pump with power cable behind the ear, a Japan first!
In March 2017, the Cardiovascular Surgery Group at Osaka University successfully implanted a left ventricular assist device with an internal power cable tunneled through the neck to the head in a patient who was ineligible for a cardiac transplantation, destination therapy (DT) trial, a Japan first. (2017-12-04)
Comparison of fecal transplant using capsule vs. colonoscopy to prevent Clostridium difficile infection
Fecal transplant administered by swallowing a capsule was no worse than transplant using colonoscopy to reduce the risk of recurrent Clostridium difficile. (2017-11-28)
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