Popular Tumors News and Current Events

Popular Tumors News and Current Events, Tumors News Articles.
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Targeted delivery of highly toxic anti-cancer drug to brain tumors
University of Houston biomedical researcher Sheeren Majd is reporting the development and testing of a new nano-carrier as a potential treatment to deliver highly toxic medicine to glioblastomas, the most common and aggressive form of primary brain tumors. (2021-02-23)

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy. (2020-06-12)

Maintenance therapy with rucaparib shows clinical responses in a subgroup of patient with pancreatic cancer
Maintenance treatment with the PARP inhibitor rucaparib (Rubraca) was well tolerated and provided clinical responses among patients with advanced BRCA- or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, according to results from an interim analysis of an ongoing phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)

UC San Diego cancer scientists identify new drug target for multiple tumor types
A dysfunctional enzyme involved in building cancer cell membranes helps fuel tumor growth; when it's disabled or depleted in mouse models, tumors shrank significantly. (2019-07-11)

Bladder cancer model could pave the way for better drug efficacy studies
In the journal Cancer Research, UNC Lineberger Comprehensive Cancer Center researchers report they have developed a model of luminal bladder cancer, one of the two subtypes of advanced bladder cancer. The researchers said this model may help them to determine which patients may respond to checkpoint inhibitors. (2018-05-21)

Molecular imaging holds promise for early intervention in common uterine cancer
A promising new molecular imaging technique may provide physicians and patients with a noninvasive way to learn more information about a type of cancer of the uterus lining called (2009-10-01)

Huntsman Cancer Institute research holds promise for personalized lung cancer treatments
New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah uncovered distinct types of tumors within small cell lung cancer that look and act differently from one another. Scientists also identified a targeted drug combination that worked well with one specific tumor type. The study was published today in Cancer Cell. The findings suggest small cell lung cancer should not be treated as a uniform disease. (2017-01-12)

Novel cancer vaccine strategy blocks death of tumor-specific cytotoxic T cells
A novel cancer vaccine strategy blocks death of tumor-specific cytotoxic T cells. (2018-05-01)

Jumbled chromosomes may dampen the immune response to tumors
How well a tumor responds to immunotherapy may depend in part on whether its chromosomes are intact or in a state of disarray, a new study reports. The finding could help doctors better pinpoint which cancer patients would benefit from immunotherapy. (2017-01-19)

Tumor-killing virus selectively targets diseased brain cells
New findings show that a specialized virus with the ability to reproduce its tumor-killing genes can selectively target tumors in the brains of mice and eliminate them. Healthy brain tissue remained virtually untouched, according to a Feb. 20 report in the Journal of Neuroscience. With more research, the technique could one day offer a novel way of treating brain cancer in humans. (2008-02-19)

Extracellular vesicles could be personalized drug delivery vehicles
Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous -- their own -- immune cells to create large amounts of fillable nanovesicles to deliver drugs to tumors in mice. (2018-03-12)

Ludwig researchers unravel novel mechanism by which tumors grow resistant to radiotherapy
A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under development. (2017-11-23)

Proposed cancer treatment may boost lung cancer stem cells, study warns
Epigenetic therapies -- targeting enzymes that alter what genes are turned on or off in a cell -- are of growing interest in the cancer field as a way of making a cancer less aggressive or less malignant. Researchers at Boston Children's Hospital now report that at least one epigenetic therapy that initially looked promising for lung cancer actually has the opposite effect, boosting cancer stem cells that are believed to drive tumors. (2018-11-19)

How bone cells promote lung cancer growth
A certain type of cell in the bone marrow can help promote tumor growth in mice with early stage lung cancer, a new study finds. (2017-11-30)

Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors
Researchers in a multi-institutional study led by Cincinnati Children's Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers -- neuroblastoma and peripheral nerve sheath tumors -- without harming healthy tissues by inserting instructions to inhibit tissue growth into an engineered virus, according to study results published in the Feb. 15 Cancer Research. (2008-02-15)

Siamab Therapeutics announces publication of new data on its ST1 lead program in the journal Oncotarget
Siamab Therapeutics Inc., a biopharmaceutical company developing novel glycan-targeted cancer therapeutics, today announced the publication of new preclinical data. (2018-05-01)

Defective DNA damage repair leads to chaos in the genome
Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known for a few years: If an important DNA repair system of the cells has failed, this promotes fragmentation and defective assembly of the genetic material. Cancer cells with such a repair defect can now possibly be treated by a specific group of drugs. (2018-11-12)

Cryoablation continues to show good results for kidney cancer patients
A review of 62 Mayo Clinic patients who underwent cryoablation to treat cancerous kidney tumors shows that the patients are cancer free for up to two and a half years after having had the procedure. (2007-11-25)

Prostate cancer cells grow with malfunction of cholesterol control in cells
Advanced prostate cancer and high blood cholesterol have long been known to be connected, but it has been a chicken-or-egg problem. Now a team led by researchers at the Duke Cancer Institute have identified a cellular process that cancer cells hijack to hoard cholesterol and fuel their growth. Identifying this process could inform the development of better ways to control cholesterol accumulation in tumors, potentially leading to improved survival for prostate cancer patients. (2017-02-21)

Personalized treatment benefits kidney cancer patients
Personalized treatment plans may extend life expectancy for early-stage kidney cancer patients who have risk factors for worsening kidney disease, according to a new study. (2019-01-15)

Treatment for male anti-NMDA receptor encephalitis patients
Treatments for the anti-NMDA receptor encephalitis usually include steroids, intravenous immunoglobulin, plasma exchange, plasmapheresis, rituximab, cyclophosphamide and tumor resection. The researchers aimed to compare the efficacy of the treatments including intravenous immunoglobulin, plasma exchange, plasmapheresis, rituximab or cyclophosphamide for male anti-NMDA receptor encephalitis patients without tumor and to discuss potential biomarkers for this disease. (2018-03-14)

Cancer's gene-determined 'immune landscape' dictates progression of prostate tumors
The field of immunotherapy -- the harnessing of patients' own immune systems to fend off cancer -- is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumors result in distinct paths of disease progression and response to therapy. (2018-01-12)

Scientists caution that a rare childhood liver cancer can spread to the brain
A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver. (2018-03-19)

Tumor growth parameters predict response to anti-angiogenic therapy in mice
Using a mathematical modeling approach, scientists have found that certain parameters of tumor growth in mice can predict the effectiveness of drugs that block formation of tumor-nourishing blood vessels. The findings are published in PLOS Computational Biology. (2017-12-21)

Anthracyclines improve survival in HER2-positive breast cancer patients
Treatment with the class of chemotherapy drugs called anthracyclines improves survival in women with HER2-positive breast cancer who have previously had surgery, but it may not offer any benefit for women with HER2-negative tumors, according to a study published online Dec. 25 in the Journal of the National Cancer Institute. (2007-12-25)

Breast cancer tumor-initiating cells use mTOR signaling to recruit suppressor cells to promote tumor
Baylor College of Medicine researchers report a new mechanism that helps cancer cells engage myeloid-derived suppressor cells. (2016-05-16)

How cells detect, mend DNA damage may improve chemotherapy
Human cells have a way of detecting and mending DNA damage caused by some common chemotherapy drugs, according to a new study from Washington University School of Medicine in St. Louis. The findings could have important implications for treating cancer. (2017-11-08)

Ludwig researchers uncover novel mechanism by which tumors evade cancer immunotherapies
A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy. (2017-11-10)

A bioengineered tattoo monitors blood calcium levels
Scientists have created a biomedical tattoo that becomes visible on the skin of mice in response to elevated levels of calcium in the blood. (2018-04-18)

Ludwig study extends potential for personalized immunotherapy to large variety of cancers
A Ludwig Cancer Research study shows that ovarian cancer, which has proved resistant to currently available immunotherapies, could be susceptible to personalized immunotherapy. (2018-03-15)

Additional therapy after surgical removal of rare tumors may not increase survival
Results of an analysis from the University of Cincinnati (UC) College of Medicine show that additional therapy, or adjuvant therapy, delivered after surgical removal of a rare type of gastrointestinal tumor does not increase survival rates for patients. (2018-03-24)

UT Dallas scientists isolate cancer stem cells using novel method
Researchers at The University of Texas at Dallas have devised a new technique to isolate aggressive cells thought to form the root of many hard-to-treat metastasized cancers -- a significant step toward developing new drugs that might target these cells. (2018-02-22)

Radiation-guided nanoparticles zero in on metastatic cancer
Zap a tumor with radiation to trigger expression of a molecule, then attack that molecule with a drug-loaded nanoparticle. (2016-06-29)

Novel classification can lead to new ways to diagnose and treat cancer
A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumor growth. A better understanding of these pathways can potentially lead to novel ways to diagnose and treat cancer. (2018-02-12)

For first time, cochlear implant restores hearing to patient with rare genetic disorder
Researchers at Georgetown University Medical Center and the National Institutes of Health have, for the first time, used a (2007-06-07)

White blood cells related to allergies may also be harnessed to destroy cancer cells
A new Tel Aviv University study finds that white blood cells which are responsible for chronic asthma and modern allergies may be used to eliminate malignant colon cancer cells. (2019-01-22)

Limiting tumors' ability to hide from the immune system
Scientists have discovered a way to stop tumors from shedding certain proteins that the immune system uses to identify and attack tumors. (2018-03-29)

Prostate cancer: New computer model enables researchers to predict course of disease
How does a normal cell turn into a deadly cancer? Seeking an answer to this Question researchers from Charité -- Universitätsmedizin Berlin examined the tumor genomes of nearly 300 prostate cancer patients. Their findings describe the ways in which changes in the prostate cells' genetic information pave the way for cancer development. Using a newly developed computer model, it is now possible to predict the course of the disease in individual patients. The results of this study were now published in Cancer Cell. (2018-12-14)

Why basal cell tumors return when drug treatment stops
A new study pinpoints a mechanism that controls how basal cell cancers respond to treatment and offers new ideas for controlling this disease when it gets tricky. (2018-02-01)

New drug seeks receptors in sarcoma cells, attacks tumors in animal trials
A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. The researchers conducted a multi-year, cross-disciplinary study that went from screening potential drug candidates to identifying and synthesizing one compound, to packaging it into nanoparticles for delivery in cells, to testing it in cell cultures and finally in mice and pigs with sarcoma tumors. (2018-12-13)

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