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Current ADHD News and Events, ADHD News Articles.
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FDA approves Adderall XR (R) to treat ADHD in adults
Shire Pharmaceuticals Group plc announced the FDA approved ADDERALL XR (R) (mixed salts of a single-entity amphetamine) as a once-daily treatment for adults with Attention Deficit Hyperactivity Disorder. ADDERALL XR was approved in the U.S. for the treatment of ADHD in children in 2001. Up to 65 percent of children with ADHD may exhibit symptoms into adulthood--about 4.4 percent of the U.S. adults. If untreated, ADHD may lead to psychological difficulties, such as depression, and occupational and social disabilities. (2004-08-12)

Proportion of Tennessee children using antipsychotic medications up significantly
The proportion of children and adolescents in Tennessee taking antipsychotic medications nearly doubled between 1996 and 2001, with the largest increase in the use of antipsychotics to treat attention-deficit/hyperactivity disorder, conduct disorder, and affective disorders, according to an article in the August issue of The Archives of Pediatrics & Adolescent Medicine, a theme issue on pediatric mental health and one of the JAMA/Archives journals. (2004-08-02)

Antipsychotic drug prescriptions nearly double for kids with ADHD
Prescriptions for atypical antipsychotic drugs for children with ADHD nearly doubled between 1996 and 2001; drugs not proven affective, side affects not well known. TV package available via satellite. (2004-08-02)

Anxiety during pregnancy affects child behavior
The idea that a woman's emotional state during pregnancy affects her unborn child has persisted for centuries. This study investigated the affect of high levels of anxiety during a woman's pregnancy on her child's susceptibility for attention deficits, hyperactivity, acting out and anxiety disorders. Findings suggest that the effect of anxiety affected the fetus more than any other factor, including smoking during pregnancy, low birthweight, or anxiety of the mother when the child is 8 or 9. (2004-07-16)

Controlling ADHD
Not all children with attention deficit hyperactivity disorder respond to stimulant drugs such as Ritalin. A new method of assessing brain biochemistry may allow physicians to accurately predict which children are unlikely to respond to stimulants, reducing the exposure of ADHD patients to drugs that are unlikely to be effective. (2004-06-22)

Parents can provide accurate reports of their children's ADHD symptoms
Traditionally, clinical trials of drugs to treat attention-deficit/hyperactivity disorder in children have relied on information provided by teachers to evaluate treatment success. An article from researchers at MassGeneral Hospital for Children verifies that parents can be as accurate as teachers in identifying ADHD symptoms and treatment-related changes in behavior. (2004-06-14)

Children with ADHD experience greater reduction of symptoms with higher doses of Concerta...
Children with attention deficit/hyperactivity disorder (ADHD) who take 36- or 54-mg doses of once-daily CONCERTA® (methylphenidate HCl) CII are more likely to achieve significantly greater symptom response and symptom reduction than children with ADHD who take CONCERTA 18 mg once daily or near-equivalent doses of methylphenidate three-times-a-day, a study shows. (2004-06-03)

Recent research finds boys have more literacy problems than girls
Recent research from the University of Warwick, Coventry and Kings College, London finds that boys really do have more reading difficulties than girls. The study into reading disabilities confirms that boys are much more prone to having trouble than girls, and it's not simply because they're more disruptive. The findings suggest boys are at least twice as likely to have dyslexia, a learning disability that involves trouble with reading. (2004-05-13)

Long-term study proves ADDERALL XR® is a safe and effective option to treat adults with ADHD
Shire Pharmaceuticals Group plc (NASDAQ: SHPGY, LSE: SHP.L, TSE: SHQ CN) announced that adults with attention-deficit/hyperactivity disorder (ADHD) experienced significant ADHD symptom control when treated with once-daily ADDERALL XR® (a mixed salts amphetamine product). The 18-month interim analysis of a two-year Phase III trial led by Harvard investigators was discussed today during a platform presentation at the American Psychiatric Association (APA) annual meeting in New York City. (2004-05-06)

Survey of adults reveals life-long consequences of ADHD
Adults with attention-deficit/hyperactivity disorder (ADHD) may have grown up with the condition, but have they outgrown its effects? Findings from a new national survey, (2004-05-06)

Mixed amphetamine salts significantly better than atomoxetine in treating children with ADHD
In one of the largest ADHD classroom trials conducted to date, children with attention-deficit/hyperactivity disorder (ADHD) achieved significantly greater improvement in both their behavior and attention, the core impairments of ADHD, with extended-release mixed amphetamine salts (MAS XR) compared to those treated with atomoxetine, reported investigators from the University of California, Irvine today at the 157th annual meeting of the American Psychiatric Association (APA) in New York. (2004-05-04)

Bupropion, counseling may help youth with ADHD stop smoking
Results of a small pilot study suggest that combining the drug bupropion with brief counseling sessions may help teens reduce or stop smoking, even those with attention deficit hyperactivity disorder (ADHD). Evidence suggests that people with ADHD have more difficulty quitting smoking than people who do not have the disorder. (2004-05-03)

Zinc supplements could help treat ADHD
As attention deficit hyperactivity disorder (ADHD) affects around 1 in every 25 school-aged children, managing this condition is of huge social importance. An article published in BMC Psychiatry this week shows that zinc supplements could increase the effectiveness of stimulants used to treat children with the disease. (2004-04-08)

Novelty-seeking teens may be more easily influenced by tobacco advertisements
Scientific data indicate that teens' receptivity to tobacco marketing campaigns may play an important role in the choice to start smoking. Building on this research, scientists at the University of Pennsylvania and Georgetown University found that teens with high levels of the novelty-seeking trait may be more than twice as likely as those low in the trait to be moderately to highly receptive to tobacco promotional campaigns. (2004-03-19)

Deficits associated with prenatal alcohol exposure can be seen as early as infancy
Most of the research on prenatal alcohol exposure has been conducted with children. A new study uses heart-rate data collected from six-month-old babies to examine the effects of alcohol consumption during pregnancy. Even as early as infancy, slower processing speeds and arousal-regulation problems are apparent. (2004-03-14)

A link between thimerosal and the brain: Can vaccines affect central nervous system function?
Scientists have found that exposure to ethanol and heavy metals (including lead, aluminum and the ethylmercury-containing preservative thimerosal) interrupt growth factor signaling, causing adverse effects on methylation reactions, which play a significant role in regulating normal DNA function and gene expression, and are critical to proper neurological development in infants and children. This work helps to explain how exposure to metals and thimerosal may lead to serious disorders of childhood, including autism and ADHD. (2004-02-05)

Reading ability and ADHD affected by same genes
Twin and family studies suggest that dyslexia, and ADHD may co-occur because of common genetic underpinnings. In a genome-wide scan of ADHD, UCLA researchers identified regions, on chromosomes 2p, 16p, 10q, and 17q, that show support for risk genes underlying reading ability. Three of the regions have been previously identified as locations of gene(s) in ADHD (10q, 16p, 17q) and one region had been identified as a location for gene(s) in dyslexia (2p). (2003-12-11)

DFG to establish seven new Clinical Research Units
The Deutsche Forschungsgemeinschaft (German Research Foundation - DFG) approved the establishment of seven new Clinical Research Units at a session of the relevant Grants Committee held on 5 December 2003. (2003-12-11)

Child health costs for behavioral disorders similar to those for physical illnesses
Children with behavioral disorders incur similar overall health care costs to children with physical disorders according to a recent study. Among behavioral disorders, costs were not uniform; anxiety and depression cost twice as much as other common behavioral disorders, mainly as a result of inpatient hospitalizations. (2003-12-08)

Imaging children with ADHD
Children with attention deficit-hyperactivity disorder (ADHD) may have significantly altered levels of important neurotransmitters in the frontal region of the brain, according to a study from the Journal of Neuropsychiatry and Clinical Neurosciences to be presented at the American Medical Association Advances in Neurology Media Briefing in New York Dec. 4. In the study, children with ADHD had a two-and-half-fold increased level of glutamate, an excitatory brain chemical that can be toxic to nerve cells. (2003-12-04)

The dopamine receptor D1 gene and ADHD: A piece of the genetic puzzle?
Attention-deficit/hyperactivity disorder (ADHD) has a strong genetic basis, and because dysregulation of the dopamine system is believed to cause the disorder, dopamine system genes are considered as candidates for involvement in ADHD susceptibility. In a recent analysis of a large sample of ADHD families, researchers from Canada found evidence for involvement of the dopamine receptor D1 gene (DRD1) in ADHD, particularly in genetic risk for the inattentive symptoms of the disorder. (2003-12-03)

Brain-imaging study sheds more light on underlying cause of attention-deficit hyperactivity syndrome
Results of a US study in this week's issue of THE LANCET provide details of the underlying physical causes of attention-deficit hyperactivity syndrome, with reductions in size of some brain areas and an increase in grey matter proportions being characteristic of children with the disorder. (2003-11-20)

Scientists map maturation of the human brain
For the first time, scientists have mapped the progressive maturation of the human brain in childhood and adolescence. In other studies, they have made advances in understanding during adolescence the effects of stress, nicotine, and alcohol. (2003-11-08)

Shire receives approvable letter for adult ADDERALL XR(R) from FDA
The US Food and Drug Administration issued an approvable letter for ADDERALL XR® once-daily treatment for adults with Attention Deficit Hyperactivity Disorder (ADHD) to Shire Pharmaceuticals Group plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ). Approximately 66 percent of children with ADHD continue to suffer from the disease throughout their adult life. The National Institute of Mental Health reports that ADHD affects 8.2 million U.S. adults, of which only 360,000 receive treatment. (2003-10-20)

Adult alcoholism and attention-deficit hyperactivity disorder are connected
Attention-deficit hyperactivity disorder (ADHD) symptoms include inattention, motor hyperactivity and impulsiveness. Researchers have found a distinct phenotype or (2003-10-14)

Stanford, Packard research finds better drug therapy for children predisposed to bipolar disorder
Children with psychiatric problems who also have a high risk of developing bipolar disorder respond well to a mood-stabilizing drug, according to a study that is the first to examine the drug's effect on children predisposed to bipolar disorder. (2003-08-25)

Severe childhood ADHD may predict alcohol, substance use problems in teen years
Scientists tracking the progress of children diagnosed with attention-deficit/hyperactivity disorder (ADHD) as they became teenagers have shed new light on the link between ADHD and the risk of developing alcohol and substance use problems. The researchers found that individuals with severe problems of inattention as children were more likely than their peers to report alcohol-related problems, a greater frequency of getting drunk, and heavier and earlier use of tobacco and other drugs. (2003-08-17)

Severity of ADHD in children increases risk of drug use in adolescence
Children diagnosed with attention-deficit/hyperactivity disorder (ADHD) are more at risk for using illicit drugs, having problems with alcohol, smoking cigarettes, and using marijuana in their adolescence than children without ADHD, say researchers who report their findings on childhood predictors of later substance use in the August issue of the Journal of Abnormal Psychology, published by the American Psychological Association (APA). (2003-08-17)

Three-time Emmy Award winning actress Kathy Baker to participate in ADHD experts on call program
The fifth annual ADHD Experts on Call, hosted by Shire US Inc, will be held on Tuesday, August 26, 2003 from 8A.M. to midnight EDT. This year, three-time Emmy Award-winning actress Kathy Baker, whose 13-year old son was diagnosed with ADHD four years ago, will talk about her own experiences. Ms. Baker will answer calls with the nation's top ADHD authorities, including Dr. Howard Abikoff, NYU Child Study Center, at the national toll-free hotline, 1-888-ASK-ADHD. (2003-08-11)

UCSD researchers demonstrate enhanced ability to divide visual attention
Researchers at UCSD School of Medicine have provided new evidence that resolves a long-standing scientific controversy regarding human visual attention and the ability to divide that attention between more than one stimulus within a broad visual field. (2003-07-16)

Studies clarify diagnosis, identify possible treatment for adults with ADHD and bipolar disorder
Two studies from Massachusetts General Hospital address the challenges of diagnosing and treating individuals with both ADHD and bipolar disorder. One report clearly identifies symptoms of both disorders in study participants, supporting the theory that some individuals truly suffer from both disorders. The second finds that the antidepressant bupropion may be helpful in treating those with both ADHD and BPD. (2003-07-09)

Survey reveals adult ADHD often undiagnosed by primary care physicians
Inadequate clinical training, inexperience and the lack of a well-validated screening tool are major barriers prohibiting primary care physicians from diagnosing ADHD in adults, according to a national survey released today by New York University School of Medicine. The survey also revealed that primary care physicians would take a more active role in treating adult ADHD if these issues were addressed. (2003-06-25)

123 Altropane® SPECT shows potential as diagnostic tool for ADHD
A recent study revealed that SPECT imaging can be used to complement the standard testing and interviews used to diagnose Attention Deficit Hyperactivity Disorder (ADHD). Results comparing five normal patients and eight who had been diagnosed with ADHD showed dopamine deficiency in the ADHD group. (2003-06-23)

PET reveals increased dopamine levels in ADHD patients
Researchers conducted a study using PET technology to gauge extracellular dopamine (DA) levels in ADHD patients. The study compared changes in extracellular DA after the use of either methylphenidate, a common treatment, or a placebo in response to both a behaviorally salient stimulus (math problems displayed on cards with monetary reward) and a neutral stimulus (pictures of scenery with no monetary reward). (2003-06-23)

ADHD kids quality of life significantly improves with long-term, once-daily Adderall XR
Shire Pharmaceuticals Group plc (NASDAQ: SHPGY, LSE: SHP.L, TSE: SHQ CN) announced results from the largest attention-deficit/hyperactivity disorder (ADHD) clinical trial conducted to date demonstrating that ADHD children experienced significant quality of life improvements and symptom control when treated with a regimen that included once-daily mixed salts amphetamine product. Data from the trial, involving more than 2,900 patients, were presented on May 21, 2003 at the American Psychiatric Association annual meeting. (2003-05-21)

Study: Adults maintain significant improvement in ADHD with long-term use of amphetamine
Adults with attention-deficit-hyperactivity disorder treated long term with an extended-release mixed-salts amphetamine medication maintained significant symptom improvement with good tolerance, a new study shows. University of North Carolina at Chapel Hill researchers presented the study results - from one of the largest trials ever conducted of adult ADHD - May 21 at the American Psychiatric Association annual meeting. (2003-05-21)

Children achieve sustained ADHD symptom improvement with long-term, once-daily use of Adderall XR
Shire Pharmaceuticals Group plc (NASDAQ: SHPGY, LSE: SHP.L, TSE: SHQ CN) announced clinical trial results that showed continued, long-term treatment (two-year) using a once-daily mixed salts amphetamine product yielded significant improvements in symptom control and quality of life in children with attention-deficit/hyperactivity disorder (ADHD). Moreover, these children sustained improvement in ADHD symptoms of at least 35 percent throughout the study, presented today at the American Psychiatric Association annual meeting. (2003-05-21)

Use of medication to treat pediatric insomnia is common, study finds
Although guidelines do not exist for the use of medication to treat pediatric sleep disorders, about 75 percent of pediatricians surveyed had recommended some type of medication for that purpose within the previous six months. Pediatric sleep disturbances are among the most common and challenging complaints, and a set of clinical experience-based guidelines needs to be developed, according to a study in the May Pediatrics. (2003-05-05)

Child health costs similar for behavioral compared to physical disorders
Children with behavioral disorders incur similar overall health care costs to children with physical disorders, said researchers from The Children's Hospital of Philadelphia and the University of Pennsylvania. Among behavioral disorders, costs were not uniform; anxiety and depression cost twice as much as other common behavioral disorders, mainly as a result of inpatient hospitalizations. (2003-05-05)

Placebo study indicates lower doses may effectively treat ADHD
A significant percentage of children with attention-deficit-hyperactivity disorder did just as well when harmless placebos, pills without any specific effect, replaced some of their medications, a study led by two N.C researchers shows. (2003-05-03)

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