Current Acetaminophen News and Events

Current Acetaminophen News and Events, Acetaminophen News Articles.
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Findings of study comparing analgesics in acute post-trauma pain
The combination of a high?dose NSAID with paracetamol does not increase the analgesic effect compared to paracetamol alone. Researchers also found that paracetamol alone is superior to high?dose NSAID alone for posttraumatic extremity pain. (2021-02-08)

Study introduces mRNA-LNP as a safe therapeutic intervention for liver regeneration
When severely or chronically injured, the liver loses its ability to regenerate. A new study led by researchers at the Center for Regenerative Medicine at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) now describes a safe new potential therapeutic tool for the recovery of liver function in chronic and acute liver diseases. (2021-01-27)

Pain-relief regimen treats trauma patients with fewer opioid drugs
A multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients. (2021-01-21)

Modified pain management strategy reduces opioid exposure to trauma patients, study shows
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at UTHealth. (2021-01-21)

Knee OA guidance for clinicians simplified and streamlined
Researchers review the similarities and differences between OARSI and ESCEO 2019 guidelines for the management of knee OA and provide a narrative to help steer health-care providers through the complexities of non-surgical management of the disease. (2020-10-29)

A pain reliever that alters perceptions of risk
While acetaminophen is helping you deal with your headache, it may also be making you more willing to take risks, a new study suggests. People who took acetaminophen rated activities like ''bungee jumping off a tall bridge'' and ''speaking your mind about an unpopular issue in a meeting at work'' as less risky than people who took a placebo, researchers found. (2020-09-08)

Study finds increase in number, severity of suicide-related calls to US Poison Control
Researchers at the Center for Injury Research and Policy and the Central Ohio Poison Center at Nationwide Children's Hospital analyzed the 549,807 calls made to Poison Control Centers (PCCs) in the U.S. for suicide-related cases involving OTC analgesics from 2000 through 2018 and found that both the overall number and rate of these cases increased significantly by 57% and 34%, respectively, during this period. (2020-07-27)

Research shows ibuprofen does not hinder bone fracture healing in children
Doctors have traditionally avoided prescribing nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen to patients with fractures. However, a new study from the University of Missouri School of Medicine and MU Health Care shows ibuprofen is an effective medication for fracture pain in children and its use does not affect fracture healing. (2020-07-22)

Le Bonheur Children's Hospital trial: Intravenous indomethacin more effective for hsPDAs
Le Bonheur and the University of Tennessee Health Science Center neonatologists, led by Jennifer M. Davidson, DO, conducted a randomized trial for the treatment of hemodynamically significant PDAs (hsPDAs) in very low birth weight (VLBW) infants. Echocardiogram criteria before and after treatment showed that IV indomethacin was more effective. (2020-07-22)

Using electricity to break down pollutants left over after wastewater treatment
Pesticides, pharmaceutical products, and endocrine disruptors are some of the emerging contaminants often found in treated domestic wastewater, even after secondary treatment. Professor Patrick Drogui of the Institut national de la recherche scientifique (INRS) and his team have tested the effectiveness of a tertiary treatment process using electricity in partnership with the European Membrane Institute in Montpellier (IEM) and Université Paris-Est. (2020-07-09)

LSU Health New Orleans discovers new class of safer analgesics
Researchers at LSU Health New Orleans Neuroscience Center of Excellence and colleagues have discovered a new class of pipeline drugs to relieve pain and reduce fever without the danger of addiction or damage to the liver or kidneys. (2020-07-06)

Study finds surge in hydroxychloroquine/chloroquine prescriptions during COVID-19
A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic. (2020-05-28)

Specially designed footwear reduces pain of knee osteoarthritis
Wearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee osteoarthritis. (2020-05-12)

More research on addiction potential needed for use of opioids to treat children's pain
A pair of new studies led by University of Alberta pediatricians indicate that parents are more reluctant to have opioids prescribed for their children than doctors are to prescribe them. (2020-03-25)

Ouch: Patients prescribed opioids after tooth extraction report worse pain
The use of opioids to soothe the pain of a pulled tooth could be drastically reduced or eliminated altogether from dentistry, say University of Michigan researchers. (2020-03-13)

Even damaged livers can handle life-saving medication
Doctors used to make patients with drug-induced liver injury stop taking all their medications until the liver healed, but this could be dangerous. Now, researchers report in two recent papers that people with diabetes, hypertension and depression might be able to continue taking life saving medications even while they heal from drug-induced liver injuries. (2020-02-28)

Study: Patients commonly prescribed opioids and antibiotics for dental conditions at EDs
A study in the March issue of The Journal of the American Dental Association from the Centers for Disease Control and Prevention found that antibiotics and opioids are frequently prescribed during emergency department visits for dental conditions, further emphasizing the need for continued efforts to combat both opioid abuse and overuse of antibiotics. (2020-02-24)

Recent research points the way toward a practical nutraceutical strategy for coping with RNA virus infections including influenza and coronavirus
In a compelling article in Progress in Cardiovascular Diseases, published by Elsevier, Mark McCarty of the Catalytic Longevity Foundation, San Diego, CA, USA, and James DiNicolantonio, PharmD, a cardiovascular research scientist at Saint Luke's Mid America Heart Institute, Kansas City, MO, USA, propose that certain nutraceuticals may help provide relief to people infected with encapsulated RNA viruses such as influenza and coronavirus. (2020-02-24)

A prescription for the pain of rejection: Acetaminophen and forgiveness
A study, published recently in the Annals of Behavioral Medicine may have found an antidote to heartbreak -- forgiveness combined with acetaminophen, the active ingredient in Tylenol. (2020-02-14)

Choosing common pain relievers: It's complicated
About 29 million Americans use over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain. Every year in the US, NSAID use is attributed to approximately 100,000 hospitalizations and 17,000 deaths. All of these drugs have benefits and risks, but deciding which one to use is complicated for health care providers and their patients. To assist in clinical decision-making, researchers address cardiovascular risks and beyond, which include gastrointestinal and kidney side effects of pain relievers. (2020-02-05)

More than half of US opioid prescriptions for dental procedures exceeded 3-day supply recommendations from CDC 2016 guidelines
Dentists are among top prescribers of opioids in the US, however, whether their opioid prescribing exceeds guidance had not been investigated. A new study in the American Journal of Preventive Medicine indicates that more than half of opioid prescriptions issued by dentists exceed the three-day supply recommended by the CDC for acute dental pain management. The findings also show that 29% of dental patients received more powerful opioids than needed for expected post-procedure pain. (2020-02-04)

More than half of dental prescriptions for opioids exceed pain-management guidelines
A new study suggests that roughly half of the opioid prescriptions written by dentists in the United States exceed the 3-day supply recommended by federal dental pain-management guidelines. (2020-02-04)

Emerging organic contaminant levels greatly influenced by stream flows, seasons
Flow rates and time of year must be taken into account to better understand the potential risks posed by emerging organic contaminants in rivers and streams, according to Penn State researchers who studied contaminant concentrations and flow characteristics at six locations near drinking water intakes in the Susquehanna River basin. (2020-01-29)

Fewer than half of California pharmacies provide correct drug disposal info
Fewer than half of California pharmacies provided correct prescription drug disposal details, a percentage that dropped if 'secret shoppers' made their call on a weekend, according to a brief research report published online Dec. 31, 2019, in Annals of Internal Medicine. (2019-12-30)

Pharmacies leave customers hanging when it comes to disposing of antibiotics and opioids
A telephone survey conducted by researchers at UC San Francisco found that fewer than half of California pharmacies provided disposal instructions meeting US Food and Drug Administration guidelines, and just 10% followed the FDA's preferred recommendation to take back unused medications from their customers. (2019-12-30)

UTHealth's Cynthia Ju awarded NIH grants for liver injury research
Tiny solutions are being sought for big liver problems by a scientist at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). (2019-12-20)

Medication use during pregnancy is common in women with preeclampsia
Use of medications during pregnancy is more common in women with preeclampsia than in those without, according to a British Journal of Clinical Pharmacology analysis of women who gave birth at a hospital in Finland in 2002-2016. (2019-11-06)

Liver-chip predicts the toxicity of drug candidates across species
Researchers have created a 'Liver-Chip' using Organs-on-Chips technology that can predict and characterize the liver toxicity of various drug candidates and compounds in rats, dogs, and humans. (2019-11-06)

Study calculates links between prescription medications and risk for suicide
A review of 922 prescription medications taken by almost 150 million people over an 11-year period shows that just 10 of these drugs were associated with an increased rate of suicide attempts. (2019-11-05)

NIH-funded study suggests acetaminophen in pregnancy linked to higher risk of ADHD, autism
Exposure to acetaminophen in the womb may increase a child's risk for attention deficit/hyperactivity disorder and autism spectrum disorder, suggests a study funded by the National Institutes of Health and the Agency for Health Care Research and Quality. (2019-10-30)

Study examines fetal exposure to acetaminophen, risk of childhood ADHD, ASD
Umbilical cord blood samples were used to examine an association between fetal exposure to acetaminophen and risk of childhood attention-deficit/hyperactivity disorder, autism spectrum disorder and other developmental disabilities in a group of nearly 1,000 mother-child pairs. (2019-10-30)

33% of people on anticoagulants take OTC supplements with potentially serious interactions
Nearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban used over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding. People on these medications largely lacked knowledge of some potentially serious interactions. Direct-acting oral anticoagulants are the drug of choice for stroke prevention in patients with atrial fibrillation, which occurs most frequently in older patients. (2019-10-28)

Antibiotics not necessary for most toothaches, according to new ADA guideline
The American Dental Association (ADA) announced today a new guideline indicating that in most cases, antibiotics are not recommended for toothaches. This guidance, published in the November issue of the Journal of the American Dental Association, aligns with the ADA's longstanding antibiotic stewardship efforts and its pledged commitment to the US government's Antimicrobial Resistance Challenge. (2019-10-25)

Opioids often prescribed after cesarean delivery even when not needed
Nearly 90% of women who did not use opioids in the hospital after cesarean delivery were nonetheless discharged with a prescription for opioids, according to a study presented at the ANESTHESIOLOGY® 2019 annual meeting. A related study showed opioid prescribing upon discharge remained high, even after improvements were made to effectively manage pain after cesarean delivery with other medications during patients' hospital stays. (2019-10-20)

One-third of children having tonsillectomies benefitted from opioid-free surgery and recovery
Nearly one-third of children who had surgery to remove their tonsils did not need opioids to get adequate pain relief during and after surgery, according to a study presented at the ANESTHESIOLOGY® 2019 annual meeting. (2019-10-20)

Colorectal surgery patients use fewer opioids, report less pain with enhanced recovery after surgery
Colorectal surgery patients who were a part of an enhanced recovery after surgery (ERAS) program had less pain, while using nearly half as many opioids, according to research being presented at the ANESTHESIOLOGY® 2019 annual meeting. (2019-10-19)

Room for improvement in drug dosage timing in hospitals
Study of 500K doses of 12 drugs led by Cincinnati Children's shows that hospitals provide medications according to staffing schedules rather than the ideal dosing times for their patients. (2019-10-01)

Childhood behavior linked to taking paracetamol in pregnancy
A new study by the University of Bristol adds to evidence that links potential adverse effects of taking paracetamol (also known as acetaminophen) during pregnancy. (2019-09-15)

Pain medication use by children after common surgeries
About 400 caregivers reported pain medication use by children after common surgeries such as hernia, elbow fracture, appendectomy or adenoid removal in this study. Most reported using acetaminophen or ibuprofen or both; 88 patients (22%) were prescribed an opioid at hospital discharge and most used less than prescribed. (2019-09-04)

Reducing exposure to opioids after cesarean delivery
An effort to improve the scheduled cesarean section delivery experience found that changes to preoperative and postoperative processes can lead to reductions in opioid use without increased pain and with faster recovery, according to research from Kaiser Permanente published in the journal Obstetrics & Gynecology. (2019-08-08)

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