Current Alpha News and Events

Current Alpha News and Events, Alpha News Articles.
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How inflammatory signalling molecules contribute to carcinogenesis
A team of MedUni Vienna researchers led by Johannes A. Schmid at the Center for Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, has managed to identify a previously unknown molecular connection between an inflammatory signalling molecule and one of the main oncogenes. The study has been published in the leading journal 'Molecular Cancer'. (2021-02-17)

On the quest for other Earths
An international research team with members from ETH has developed a new method for directly imaging smaller planets in the habitable zone of a neighbouring star system. This opens up new possibilities in the search for extraterrestrial life. (2021-02-17)

Dopamine is key to the mystery of metabolic dysfunction in psychiatric patients
Antipsychotic drugs not only block dopamine signaling in the brain but also in the pancreas, leading to uncontrolled production of blood glucose-regulating hormones, obesity and diabetes. (2021-02-15)

Function identified of 'mystery protein' that kills brain cells of people with Parkinson's
Scientists have made a 'vital step' towards understanding the origins of Parkinson's Disease - the fastest growing neurological condition in the world. A study published in Nature Communications today (Wednesday 10 February) presents a compelling new evidence about what a key protein called alpha-synuclein actually does in neurons in the brain. (2021-02-10)

A new way to look for life-sustaining planets
A new system for mid-infrared exoplanet imaging in combination with long observation time allows ground-based telescopes to directly capture images of planets about three times the size of Earth within the habitable zones of nearby stars. (2021-02-10)

A new method to search for potentially habitable planets
Imaging planets orbiting around nearby stars, which could potentially harbour life, has become a possibility thanks to the progress made in observational methods by an international team of astronomers, including Olivier Absil and Anne-Lise Maire, astrophysicists at the STAR Institute of ULiège. First candidate: Alpha Centauri, a system similar to ours, ''only'' 4.3 light years away. This study is the subject of a publication in the journal Nature Communications. (2021-02-10)

As you look around, mental images bounce between right and left brain
A new study in Neuron explains how the brain helps us remember what we've seen, even as it shifts around in our visual system. That ability--to remember that something is the same thing no matter how it's moving around relative to our eyes--is what gives us the freedom to control where we look. (2021-02-08)

'Brain training' may be an effective treatment for post-traumatic stress disorder
Neurofeedback, also called 'brain training,' consists of exercises where individuals regulate their own brain activity. In a new study, researchers have found that neurofeedback may be an effective treatment for individuals with post-traumatic stress disorder. (2021-01-26)

Alpha particles lurk at the surface of neutron-rich nuclei
Scientists from an international collaboration have found evidence of alpha particles at the surface of neutron-rich heavy nuclei, providing new insights into the structure of neutron stars, as well as the process of alpha decay. (2021-01-21)

New Parkinson's disease therapeutics discovered by Ben-Gurion U researchers
Dr. Claude Brodski, M.D., head of the BGU's Laboratory for Molecular Neuroscience, discovered that BMP5/7 signaling in neurons was significantly reduced in dopamine-producing brain cells, which could contribute to Parkinson's disease advancement. (2021-01-20)

Where do our minds wander? Brain waves can point the way
Anyone who has tried and failed to meditate knows that our minds are rarely still. But where do they roam? New research led by the University of California, Berkeley, has come up with a way to track the flow of our internal thought processes and signal whether our minds are focused, fixated or wandering. (2021-01-19)

New way to control electrical charge in 2D materials: Put a flake on it
Gaining control of the flow of electrical current through atomically thin materials is important to potential future applications in photovoltaics or computing. Physicists in Arts & Sciences at Washington University in St. Louis have discovered one way to locally add electrical charge to a graphene device. (2021-01-14)

Alpha-ray missile therapy: tumor cells attacked from intracellular region
Researchers from Osaka University have innovated a technique of irradiating cancer from within. They tagged α-methyl-L-tyrosine with 211Astatine, an α-emitter, to prepare 211At-AAMT; this radiopharmaceutical was effectively conveyed into cancer cells by the amino acid transporter LAT1. Alpha radiation combines high linear energy transfer with minimal tissue penetration, damaging cancer cells lethally while sparing surrounding normal tissue. This strategy may prove a breakthrough in the management of intractable or advanced cancers. (2021-01-04)

Novel public-private partnership facilitates development of fusion energy
PPPL working in coordination with MIT's Plasma Science and Fusion Center and Commonwealth Fusion Systems to develop a unique tokamak fusion device called ''SPARC.'' (2020-12-30)

New diagnostic isotope to enhance targeted alpha therapy for cancer
Researchers in the DOE Isotope Program have developed an effective radionuclide, cerium-134, as a paired analogue of actinium and thorium that can be imaged using positron emission tomography (PET). (2020-12-16)

Scientists recruit new atomic heavyweights in targeted fight against cancer
Researchers from the U.S. Department of Energy's Berkeley Lab and Los Alamos National Laboratory have developed new methods for the large-scale production, purification, and use of the radioisotope cerium-134, which could serve as a PET imaging radiotracer for a highly targeted cancer treatment known as alpha-particle therapy. (2020-12-14)

Way to support effective brain performance after head injury backgrounded by lack of sleep
Scientists from the School of Biomedicine of Far Eastern Federal University (FEFU) with colleagues from Italy, Spain, Romania, and Sweden suggest a way to protect the brain and minimize neurodegenerative processes after concussion head injuries in the presence of extensive previous sleep deprivation. This methodology is especially important given the retirement-age increase that has recently become an international trend. A related article appears in the Progress in Brain Research journal. (2020-12-08)

Useful 'fake' peptides
Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units. These oligoureas, which are composed of urea-based units, fold into a structure similar to that of peptides. Oligourea-based 'fake' peptides enhance the options for rational drug design, concludes the study published in the journal Angewandte Chemie. (2020-12-07)

Supernova surprise creates elemental mystery
Michigan State University (MSU) researchers have discovered that one of the most important reactions in the universe can get a huge and unexpected boost inside exploding stars known as supernovae. (2020-12-02)

The shorter the delay, the more effective the neurofeedback
HSE University scientists have for the first time in the world investigated the impact of delayed reinforcement signals in neurofeedback (NFB) training. They have experimentally proven that reducing the delay in feedback (decreasing feedback latency) can significantly increase the efficacy of training. This opens up new potential for the use of NFB for cognitive enhancement, self-regulation, and the treatment of a broad range of neurological disorders from anxiety and depression to epilepsy. (2020-12-01)

Alpha animals must bow to the majority when they abuse their power
Democratic decision-making allows subordinate vulturine guineafowl to regain control over collective group actions when dominants have a monopoly over resources. (2020-11-26)

Brain waves guide us in spotlighting surprises
A new study by MIT and Boston University neuroscientists finds that the dynamic interplay of different brain wave frequencies, rather than dedicated circuitry, appears to govern the brain's knack for highlighting what's surprising and downplaying what's predictable. (2020-11-24)

Ancient interleukins 2, 15, and 15-like exhibited distinct functions but all bound IL-15Ra
Interleukin-15-like (IL-15L) is found in both fish and mammals and may be the last remaining cytokine shared between those species for which the function had not been determined yet. Scientists now report the first functional analysis of cytokine IL-15L which, similar to related IL-15 and primitive IL-2, forms a complex with receptor chain IL-15Ra, but in contrast to these cytokines selectively induces a type 2 immune response. (2020-11-20)

In the lab, St. Jude scientists identify possible COVID-19 treatment
Immunologists have determined the process driving life-threatening inflammation, lung damage and organ failure in patients with COVID-19, sepsis and other inflammatory disorders suggesting possible treatment using existing drugs. (2020-11-18)

Rapid test shows 'solid performance' for diagnosing infection around joint implants
The recently FDA-authorized alpha-defensin lateral flow test is a highly accurate, ten-minute test for diagnosis of periprosthetic joint infection (PJI) - a serious and costly complication of total joint replacement, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer. (2020-11-09)

Stanford researchers link poor memory to attention lapses and media multitasking
Stanford researchers are connecting the dots between attention and memory to explain why we remember certain things and forget others, why some people remember better than others and how media multitasking affects how well we recall. (2020-10-28)

Gender insecurity prompts women MMA fighters to date hypermasculine men
Women who compete in martial arts and combat sports challenge gender norms in their profession but often embrace them wholeheartedly and even overdo them in their personal lives, finds a UC Riverside study published in Sociology of Sport Journal. The findings underscore the need for caution when assigning a feminist label to an organization or activity simply because it features women in powerful positions. (2020-10-22)

The new heavy isotope mendelevium-244 and a puzzling short-lived fission activity
A team of scientists from GSI Helmholtzzentrum fuer Schwerionenforschung Darmstadt, University Mainz (JGU), Helmholtz Institute Mainz (HIM) and the University of Jyvaeskylae, Finland, has provided new insights into the fission processes in exotic nuclei and for this, has produced the hitherto unknown nucleus mendelevium-244. The experiments were part of ''FAIR Phase 0'', the first stage of the FAIR experimental program. The results have now been published in the journal ''Physical Review Letters''. (2020-10-21)

Diagnosing Parkinson's disease with skin samples could lead to earlier detection
New research shows a simple skin test can accurately identify Parkinson's disease, which could lead to earlier detection of the disease and better outcomes for patients. Currently, Parkinson's disease is diagnosed by clinical signs and symptoms but only definitively diagnosed at autopsy. The researchers conducted a blinded study of 50 skin samples using an assay originally designed to detect mad cow disease. (2020-10-21)

Oncotarget: Th1 cytokines potentiate apoptosis of breast cancer cells and suppress tumor growth
Volume 11, Issue 30 of Oncotarget reported that previously, the authors showed that anti-estrogen drugs combined with a dendritic cell-based anti-HER-2 vaccine known to induce strong Th1-polarized immunity dramatically improved clinical response rates in patients with HER-2pos/ERpos early breast cancer. (2020-10-18)

Scientists who discovered SARS just revealed the immune system's response to COVID-19
In this study, which was published in the journal Frontiers in Immunology on September 30th, researchers used sequencing to characterize the immune system of patients who survive from COVID-19 infection from symptom onset through recovery. This study captured, for the first time, the expansion and contraction of all seven chains in the immune repertoire. (2020-10-13)

Oncotarget: Exosomes secreted under hypoxia enhance stemness in Ewing's sarcoma
The cover for issue 40 of Oncotarget features Figure 5, ''miR-210 silences the proapoptosis member CASP8AP2,'' by Kling, et al. which reported that hypoxic Ewing's sarcoma cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS cells by enhancing survival. (2020-10-08)

New research provides clues on optimizing cell defenses when viruses attack
Researchers studying interferons, immune response proteins released naturally by human cells when viruses are detected, have uncovered new details on the mechanisms underlying cell defenses. They describe the intricate, time-dependent regulatory mechanisms that human cells use to control the duration and strength of antiviral responses triggered by interferon. Based on these findings, researchers are now able to design time-dependent administrations of interferon to minimize inhibitory factors and boost therapeutic responses. (2020-09-29)

New potential treatment approach for patients with salt sensitive hypertension
A new study from Boston University School of Medicine (BUSM) has found that an alpha adrenoceptor blocker (a class of drugs that relaxes smooth muscle or blood vessels) may represent a new treatment approach for patients with salt sensitive hypertension. This is the first study to demonstrate that α1-adrenoceptor antagonism reduces the activity of a mechanism in the kidney that reabsorbs salt to reduce blood pressure. (2020-09-28)

Study shows vitamin E needed for proper nervous system development
- In research with key ramifications for women of childbearing age, scientists show that embryos produced by vitamin E-deficient zebrafish have malformed brains and nervous systems. (2020-09-21)

Researchers discover new molecules for tracking Parkinson's disease
New research describes an innovative method for identifying molecules that can help track the progression of Parkinson's disease. This proof-of-concept study could change the paradigm for how researchers screen and test new molecules for studying a wide range of neurodegenerative diseases. (2020-09-21)

NASA satellite found Post-Tropical Storm Alpha fizzle over Portugal and Spain
Former Subtropical Storm Alpha was a short-lived storm that formed and fizzled within 24 hours. NASA-NOAA's Suomi NPP satellite found the remnants of former Subtropical storm Alpha spreading over Portugal and northwestern Spain. (2020-09-21)

NASA's aqua satellite helps confirm subtropical storm alpha
Subtropical Storm Alpha has formed near the coast of Portugal, becoming the first named storm using the Greek Alphabet list, now that the annual list of names is exhausted. NASA's Aqua satellite obtained visible imagery of the new storm. (2020-09-18)

Henry ford study finds certain immuno suppressing drugs do not increase risk for COVID-19
Patients on immunosuppressive therapy for common skin and rheumatic diseases like psoriasis and rheumatoid arthritis are not at increased risk for contracting COVID-19 and should continue taking their medicine as prescribed, say Henry Ford Health System dermatology researchers in a study published in the Journal of the American Academy of Dermatology. (2020-09-14)

Mineral undergoes self-healing of irradiation damage
Several minerals suffer radioactive self-irradiation and hence experience long-term changes of their properties. The mineral monazite virtually behaves ''just alike Camembert cheese in which holes are drilled'': Existing radiation damage heals itself. An international research team led by Lutz Nasdala, Institute of Mineralogy and Crystallography, University of Vienna, conducted an ion-irradiation study that has unravelled the causes of the self-healing of monazite. Results were published in ''Scientific Reports''. (2020-09-09)

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