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Current Amino Acid News and Events, Amino Acid News Articles.
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Simple and cost-effective extraction of rare metals from industrial waste
Researchers from Kanazawa University developed a protocol to efficiently purify palladium and silver ions from industrial waste, and convert the ions into pure metallic elements. This will help increase global stock of valuable elements that are widely needed yet in scarce supply. (2020-12-18)

Researchers determine how often cancer patients develop osteonecrosis of the jaw
A landmark study by researchers from the SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), has found that 2.8 percent of patients on average develop osteonecrosis of the jaw, or ONJ, within three years of starting a common treatment for cancer that has spread to the bone. (2020-12-17)

LSU health research suggests new mechanism to balance emotional behavior
Research led by Si-Qiong June Liu, MD, PhD, Professor of Cell Biology and Anatomy at LSU Health New Orleans School of Medicine, discovered a surprising reciprocal interaction between chemicals in the brain resulting in accelerated loss of molecules that regulate brain cell communication. (2020-12-17)

Optogenetic method can reveal how gut microbes affect longevity
Optogenetics offers a direct way to manipulate gut bacterial metabolism in a temporally, quantitatively and spatially controlled manner and enhance host fitness. (2020-12-17)

Researchers discover brain pattern that could improve mental health disorder diagnosis
A pattern in how the brain breaks down tryptophan, a common amino acid consumed through food, was discovered by researchers at UTHealth. (2020-12-17)

Fish oil supplements don't raise bad cholesterol
The Fatty Acid Research Institute (FARI) has published a new research paper in conjunction with The Cooper Institute on the omega-3s EPA and DHA in fish oil and low density lipoprotein cholesterol (LDL-C). (2020-12-17)

Modulating cells' chloride channels
Daegu Gyeongbuk Institute of Science and Technology (DGIST) researchers gain deeper insight into a cell membrane channel, with potential implications for drug development. (2020-12-16)

Oral hormone therapy shown to significantly alter metabolome of menopausal women
Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women. This finding, which examined blood specimens from the landmark Women's Health Initiative (WHI) study, may help explain the disease risks and protective effects associated with different regimens of hormone therapy. (2020-12-16)

Resistance training paired with peanut protein affects muscle health in older adults
Researchers from Auburn University have found that when combined with resistance training, defatted peanut powder can be an effective plant-based protein option for positively affecting select markers of muscle growth and strength in untrained older adults. (2020-12-15)

Chemists from RUDN University synthesized chitin-based antibiotics
?hemists from RUDN University discovered previously unknown derivatives of chitin, a biopolymer that forms the exoskeletons of insects and carapaces of crayfish and other arthropods. The new compounds and their nanoparticles have antibacterial properties and are able to catalyze chemical reactions. (2020-12-14)

Mass extinctions of land-dwelling animals occur in 27-million-year cycle
Mass extinctions of land-dwelling animals--including amphibians, reptiles, mammals, and birds--follow a cycle of about 27 million years, coinciding with previously reported mass extinctions of ocean life, according to a new analysis published in the journal Historical Biology. (2020-12-11)

Scientists found out genes involved in a compound in lichens with antiviral activity
Lichens are of great importance both ecologically and as a biological model. These organisms produce a wide range of secondary metabolites, including usnic acid, a compound with unknown biological function but which in-vitro studies have found to present antiviral, neuroprotective and anti-cancer activity. An international research team led by the Complutense University of Madrid has identified the cluster of biosynthetic genes involved in the production of this compound. (2020-12-11)

tRNA fragments are involved in poststroke immune reactions
Following a stroke, the immune system triggers an inflammatory reaction that can either overshoot or turn into an immune deficiency. Now, a team of researchers - among them scientists from Goethe University Frankfurt, Germany - has shown that tRNA fragments play a role in this immune reaction. Fragments of tRNAs, which transport amino acids during protein synthesis ('transfer RNA'), were long merely considered cellular waste. The researcher's aim: To find new target structures for therapeutics. (2020-12-11)

Rapid lateral flow immunoassay developed for fluorescence detection of SARS-CoV-2 RNA
Scientists from the Suzhou Institute of Biomedical Engineering and Technology have developed a novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on hybrid capture fluorescence immunoassay (HC-FIA). (2020-12-10)

Amino acid recycling in cells: Autophagy helps cells adapt to changing conditions
Scientists at Tokyo Institute of Technology (Tokyo Tech), Japan, have shown for the first time how specific metabolites produced by autophagy are utilized by a cell. They discovered that in budding yeast adapting to respiratory growth, autophagy--an intracellular recycling system--recycles the amino acid serine to trigger growth through mitochondrial one-carbon metabolism. This study shows how the recycling function of autophagy is crucial for adaptation to fluctuating environmental conditions. (2020-12-10)

A genetic shortcut to help visualize proteins at work
A group at Gladstone Institutes and UC San Francisco (UCSF) has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of protein complexes. Their findings are published in the journal Science. (2020-12-10)

Signs of healthy aging found in ergothioneine telomere study
Signs of healthy aging found in ergothioneine telomere in vitro study, published in the Journal of Dietary Supplements, demonstrating Blue California ErgoActive ergothioneine helped to preserve telomere length and reduced the rate of telomere shortening under oxidative stress. The conclusion suggests ergothioneine helps to support healthy aging. (2020-12-10)

Tomatoes offer affordable source of Parkinson's disease drug
Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines. (2020-12-09)

UL, Ireland, research finds promising treatment to protect kidney function in diabetes
A clinical trial involving researchers at University of Limerick, Ireland has demonstrated the potential benefits of new drugs in protecting kidney function in diabetes. (2020-12-09)

Memory deficits resulting from epigenetic changes in Alzheimer's disease can be reversed
Memory loss associated with Alzheimer's disease (AD) may be able to be restored by inhibiting certain enzymes involved in abnormal gene transcription, according to a preclinical study by researchers at the University at Buffalo. (2020-12-09)

Pollution from cooking remains in atmosphere for longer - study
Particulate emissions from cooking stay in the atmosphere for longer than previously thought, making a prolonged contribution to poor air quality and human health, according to a new study. (2020-12-08)

New treatment in development for irritable bowel syndrome with constipation
Researchers devised a plan to treat IBS with constipation by delivering chenodeoxycholic acid in a bilayered capsule, finding that this mode of delivery could decrease colon cramping and thus produce a better patient experience. (2020-12-08)

Key building block for organic molecules discovered in meteorites
Scientists from Japan and the USA have confirmed the presence in meteorites of a key organic molecule which may have been used to build other organic molecules, including some used by life. The discovery validates theories of the formation of organic compounds in extraterrestrial environments. (2020-12-07)

Development of a new method for decoding viral genes
A research team led by Professor Yasushi Kawaguchi of the Institute of Medical Science, the University of Tokyo, developed a new decoding method for viral genes that can easily and quickly obtain even non-canonical genetic information. Using this new decoding method, they identified nine novel proteins encoded by herpes simplex virus type 1(HSV-1) and found that one of them, piUL49, is a pathogenic factor that specifically controls the onset of herpes encephalitis . (2020-12-07)

Arctic ground squirrels recycle nutrients to endure deep hibernation
By studying the body chemistry of hibernating Arctic ground squirrels, researchers have found that the animals are able to recycle their body's own nutrients to survive during a long, inactive winter. A University of Alaska Fairbanks-led study monitored ground squirrels in a laboratory environment for two years, measuring the almost undetectable flow of nutrients through their hibernating bodies. Researchers found that the animals were able to convert the free nitrogen they were creating into amino acids. (2020-12-07)

Useful 'fake' peptides
Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units. These oligoureas, which are composed of urea-based units, fold into a structure similar to that of peptides. Oligourea-based 'fake' peptides enhance the options for rational drug design, concludes the study published in the journal Angewandte Chemie. (2020-12-07)

A recipe for protein footprinting
By publishing their method in the journal Nature Protocols, chemists have opened doors for fellow scientists to better address research questions related to Alzheimer's disease, the COVID-19 pandemic and more. (2020-12-07)

Biologists from RUDN University discovered the secret of flaxseed oil with long shelf life
Biologists from RUDN University working together with their colleagues from the Institute of Molecular Biology of the Russian Academy of Sciences and the Institute of Flax studied the genes that determine the fatty acid composition in flaxseed oil and identified polymorphisms in six of them. The team also found out what gene variations could extend the shelf life of flaxseed oil. This data can be used to improve the genetic selection of new flax breeds. (2020-12-04)

The helix of life: New study shows how 'our' RNA stably binds to artificial nucleic acids
Xeno nucleic acids are essential for the development of nucleic acid-based drugs. To be effective, they need to be able to stably bind to natural RNA (a cellular single-stranded version of the DNA, which is essential for all body processes). However, it is unclear how, if at all, RNA hybridizes with these xeno nucleic acids. A new study sheds light on this mechanism, opening doors to the development of potentially revolutionary nucleic acid-based drugs. (2020-12-03)

Amino acid connected to NAFLD could provide treatment clues
Basic science research explores the effects of impaired glycine metabolism in nonalcoholic fatty liver disease - and how to potentially use glycine-based treatment to help people with NAFLD. (2020-12-03)

What makes certain groups more vulnerable to COVID-19?
What makes the elderly and people with underlying conditions more vulnerable to COVID-19? According to a new study led by McGill University researchers, clues can be found in the proteins involved in initiating infection, as the virus binds to host cells of different animals. Greater cellular oxidation with aging and sickness may explain why seniors and people with chronic illness get infected more often and more severely. (2020-12-03)

Study finds 10 metabolites associated with risk of stroke
Metabolites are small molecules found in our body's cells. They come from the food we eat, chemical processes happening within our bodies and microbes. A new analysis of recent studies has found that the levels of 10 metabolites detected in the blood are associated with a person's risk of stroke. The research is published in the December 2, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. (2020-12-02)

NUS engineers invent fast and safe way to store natural gas for useful applications
Engineers from NUS have devised a method to convert natural gas into a non-explosive solid form known as gas hydrates, which can be easily stored and transported. Using a novel, low-toxicity additive mixture, the conversion can be completed in just 15 minutes - the fastest time ever reported. (2020-12-02)

Breaking the rules of chemistry unlocks new reaction
Scientists have broken the rules of enzyme engineering to unlock a new method for creating chemical reactions that could unlock a wide range of new applications -- from creating new drugs to food production. (2020-12-01)

Plants on aspirin
For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin. But what happens, if plants are treated with these painkillers? By doing so, Scientists at the Institute of Science and Technology (IST) Austria discovered an unexpected bioactivity of human pharmaceuticals in plants. The scientists published their study in the journal Cell Reports. (2020-12-01)

AI solution to a 50-year-old science challenge could 'revolutionise' medical research
Proteins form the machinery that keep all animals, plants and bacteria alive and well. Understanding the complex shapes of proteins is key to the study of life on earth as well as to tackling almost all human diseases. Despite fifty years of work, scientists have struggled to find an accurate and efficient method to determine the shapes of proteins, but researchers now say an artificial intelligence solution has been found. (2020-11-30)

Study reveals new findings on nature's UV sunscreens
Swansea University research has provided a new insight into the behaviour of nature's own UV sunscreens when they are exposed to other parts of the light spectrum. (2020-11-30)

Bacteria in iron-deficient environments process carbon sources selectively
Looking at a group of bacteria from soil, researchers at Northwestern University discovered that these organisms overcome limitation in their carbon processing machinery by rerouting their metabolic pathways to favor producing iron-scavenging compounds. (2020-11-30)

Small molecules control bacterial resistance to antibiotics
Antibiotics have revolutionized medicine by providing effective treatments for infectious diseases such as cholera. But the pathogens that cause disease are increasingly developing resistance to the antibiotics that are most commonly used. Scientists at the Friedrich Schiller University Jena, Germany have discovered a molecule that influences the antibiotic-resistance of cholera bacteria. They have published their results in the scientific journal ''Nature Communications''. (2020-11-27)

Warwick scientists design model to predict cellular drug targets against COVID-19
A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick. This study helps understand how the virus uses the host to survive, and enable drug predictions for treating the virus to be made. (2020-11-25)

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