Current Amputation News and Events

Current Amputation News and Events, Amputation News Articles.
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New surgery may enable better control of prosthetic limbs
MIT researchers in collaboration with surgeons at Harvard Medical School have devised a new type of amputation surgery that can help amputees better control their residual muscles and receive sensory feedback. This restored sense of proprioception should translate to better control of prosthetic limbs, as well as reduction of limb pain, the researchers say. (2021-02-15)

How insects activate muscles to adapt to limbs removed
Adaptability explains why insects spread so widely and why they are the most abundant animal group on earth. Insects exhibit resilient and flexible locomotion, even with drastic changes in their body structure such as losing a limb. (2021-01-14)

Mid-term clinical trial results show similar outcomes in promising cell therapies for CLI
Mid-term results of the first clinical trial designed specifically to evaluate the safety and effectiveness of two cell therapies that are showing early promise in treating angiitis-induced critical limb ischemia were released in STEM CELLS Translational Medicine. (2021-01-05)

No mortality increase with paclitaxel-coated devices in peripheral arterial disease
An interim analysis from the Swedish Drug-Elution Trial in Peripheral Arterial Disease (SWEDEPAD) has now been presented. It shows that, for patients with lower limb occlusive arterial disease, paclitaxel-coated balloons and stents do not bring about the rise in mortality previously reported. The study, led by the University of Gothenburg and published in The New England Journal of Medicine (NEJM), is expected to resonate internationally. (2020-12-09)

Neurorehabilitation experts highlight breakthroughs in neurogenic pain management
There have been significant advances in knowledge regarding the pathology, etiology, assessment, and treatment of several significant neurogenic pain disorders regularly encountered by neurorehabilitation professionals in both inpatient and outpatient care. In a collection of articles published in NeuroRehabilitation, experts describe the latest advancements in neurogenic classification and pain management and treatment of these disorders. (2020-11-18)

EULAR: Amputations of body parts: The combination of diabetes and gout significantly increases
Compared to the average population, people suffering from both gout and diabetes have a 25 times higher risk of requiring an amputation of peripheral limbs such as feet, toes or lower legs. This is the result of a study presented by experts from the US at the virtual annual congress of the European League Against Rheumatism (EULAR) 2020. (2020-08-13)

Bone-anchored leg prostheses also prove to be a valuable procedure after 5-year follow-up
After above-knee amputation, there is the option of a prosthesis that is placed directly in the thigh bone. Despite the fact that bone-anchored prostheses have been used for thirty years, researchers at Radboudumc have published the first long-term evaluation. It turns out that the procedure is not without stoma problems, but that these can usually be treated with simple measures and that the implant leads to a permanent improvement in mobility and quality of life. (2020-08-06)

Heart disease medications underused among Hispanic/Latino populations with PAD
Recommended heart medications are underused among Hispanic/Latino people with peripheral artery disease (PAD). Only a quarter to slightly more than half of Hispanic/Latino study participants with PAD reported taking recommended medications to lower blood pressure and cholesterol and to prevent blood clots. (2020-08-05)

'Good' virus for common infection
Australian researchers have shown how viruses can be used to save lives, developing the potential use of bacteriophages in bandages to treat life-threatening golden staph infections which may not respond to traditional antibiotics. Targeting multidrug-resistant Staphylococcus aureus ('golden staph') in diabetic foot ulcers, Flinders University microbiology researchers have joined infectious diseases and pharmaceutical partners to show the usefulness of a possible 'phage cocktail' therapy on wound infections. (2020-07-29)

Spinal stimulators repurposed to restore touch in lost limb
Devices commonly implanted for chronic pain could expand patient access to prosthetic arms that ''feel.'' (2020-07-21)

Dangerous blood clots form in leg arteries of COVID-19 patients
COVID-19 is associated with life-threatening blood clots in the arteries of the legs, according to a new study. Researchers said COVID-19 patients with symptoms of inadequate blood supply to the lower extremities tend to have larger clots and a significantly higher rate of amputation and death than uninfected people with the same condition. (2020-07-16)

3D printed insoles offers new hope for patients with diabetes
Scientists from Staffordshire University claim that new 3D printed insoles can significantly improve the foot health of people suffering with diabetes. (2020-06-25)

The feeling a limb doesn't belong is linked to lack of brain structure and connection
People with body integrity dysphoria (BID) often feel as though one of their healthy limbs isn't meant to be a part of their bodies. They may act as though the limb is missing or even seek its amputation 'to feel complete.' Now, researchers reporting in the journal Current Biology on May 7, 2020 have found that these feelings that a limb doesn't belong are mirrored in the brains of people with this condition. (2020-05-07)

Prime time for lower extremity artery disease
This article provides an overview of the indications and techniques of lower extremity revascularisation, and an in-depth analysis of the available evidence regarding type and duration of antiplatelet and anticoagulant treatment following endovascular and surgical revascularisation. (2020-05-06)

Children in rural communities at risk for poor lawnmower injury outcomes
Children in rural communities are 1.7 times more likely to undergo an amputation after a lawnmower injury than children in urban communities, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP). The researchers also found that although lawnmower injuries are prevalent throughout the United States, children in Southern and Midwestern states account for more than 80% of pediatric lawnmower injuries. (2020-05-01)

Researchers are developing potential treatment for chronic pain
Researchers from the University of Copenhagen have developed a new way to treat chronic pain which has been tested in mice. With a compound designed and developed by the researchers themselves, they can achieve complete pain relief. (2020-04-30)

Mind-controlled arm prostheses that 'feel' are now a part of everyday life
For the first time, people with arm amputations can experience sensations of touch in a mind-controlled arm prosthesis that they use in everyday life. A study in the New England Journal of Medicine reports on three Swedish patients who have lived, for several years, with this new technology -- one of the world's most integrated interfaces between human and machine. (2020-04-29)

Rivaroxaban reduces risk in symptomatic PAD post-intervention
People with symptomatic peripheral artery disease (PAD) who took the blood thinner rivaroxaban with aspirin after undergoing a procedure to treat blocked arteries in the leg (lower extremity revascularization) had a 15% reduction in the risk of major adverse limb and cardiovascular events when compared with those receiving aspirin alone, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

Genetically engineering electroactive materials in living cells
Merging synthetic biology and materials science, researchers genetically coaxed specific populations of neurons to manufacture electronic-tissue 'composites' within the cellular architecture of a living animal, a new proof-of-concept report reveals. (2020-03-19)

Stanford scientists discover the mathematical rules underpinning brain growth
'How do cells with complementary functions arrange themselves to construct a functioning tissue?' said study co-author Bo Wang, an assistant professor of Bioengineering. 'We chose to answer that question by studying a brain because it had been commonly assumed that the brain was too complex to have a simple patterning rule. We surprised ourselves when we discovered there was, in fact, such a rule.' (2020-03-11)

Uncovering the plastic brain of a fruitfly -- new study
Genetic mechanisms that govern brain plasticity -- the brain's ability to change and adapt -- have been uncovered by researchers at the University of Birmingham. (2020-02-18)

Fewer veterans dying or requiring amputations for critically blocked leg arteries
Between 2005 and 2014, there was a significant decline in the number of veterans hospitalized for critically blocked leg arteries. During the same period, more veterans underwent procedures to have critically blocked leg arteries opened, and fewer died or required amputation. (2020-02-13)

UConn biomedical engineer creates 'smart' bandages to heal chronic wounds
A new 'smart bandage' developed at UConn could help improve clinical care for people with chronic wounds. (2020-02-13)

Children's fingertip injuries could signal abuse
Many children who suffer fingertip injuries have been abused, according to a Rutgers study. The researchers found that children who had a documented history of abuse or neglect were 23 percent more likely to suffer a fingertip injury before age 12. The study, published in Journal of Hand Surgery Global Online, is the first to look at the link between children's fingertip injures and abuse or neglect. (2020-02-12)

What interventional radiologists need to know about frostbite and amputation
An ahead-of-print article in the April issue of the American Journal of Roentgenology (AJR) reviewing various techniques and clinical management paradigms to treat severe frostbite injuries -- relevant for interventional radiology, especially--showed promising results using both intraarterial and intravenous tissue plasminogen activator to reduce amputation. AJR's meta-analysis of thrombolytic therapy updates the guidelines for all interventional radiologists, including a suggested protocol, inclusion and exclusion criteria, and potential complications. (2020-02-06)

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma
Houston Methodist researchers propose a combination of two well-known drugs as a new treatment option for Ewing sarcoma -- one of them typically used to treat diabetes. (2019-12-16)

Recovery from years of inactivity requires focusing on doing resistance exercises rapidly
Several years of hospitalisation, one example of muscle inactivity, causes a disproportionate decline in the muscle strength known to affect balance, increase the risk of joint injuries, and hinder movements involved in sports. That's according to research from the University of Roehampton, published today in Experimental Physiology. (2019-11-26)

Clearing damaged cells out of the body helps heal diabetics' blood vessels
Research published today in Experimental Physiology shows that ramping up one of the body's waste disposal system, called autophagy, helps heal the blood vessels of diabetics. (2019-11-17)

Talk to the hand
Fans of the blockbuster movie 'Iron Man 3' might remember the characters step inside the digital projection of a 'big brain' and watch as groups of neurons are 'lit up' along the brain's neural 'map' in response to physical touch. Now, much like that scene, researchers at the University of Missouri have discovered a new insight into how the complex neural map of the human brain operates. (2019-11-05)

Injuries related to lawn mowers affect young children in rural areas most severely
Each year, more than 9,000 children in the United States are treated in emergency departments for lawn mower-related injuries. New research being presented at the American Academy of Pediatrics (AAP) 2019 National Conference & Exhibition in New Orleans found that these injuries are more frequent and severe in rural areas, affecting younger children than in urban regions. (2019-10-25)

Sensory and motor brain plasticity is not limited by location
The new function of unused cortical regions is not necessarily determined by the function of nearby cortical regions, according to new research in adults born without one hand, published in JNeurosci. (2019-10-14)

Researchers discover a new defensive mechanism against bacterial wound infections
Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité -- Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria. Central to this mechanism is a cellular messenger molecule known as 'interleukin 6', whose mode of action may be used in the future to prevent wound infections. Results from this research have been published in PNAS. (2019-10-04)

Amputees merge with their bionic leg
In an international collaboration led by scientists in Switzerland, three amputees merge with their bionic prosthetic legs as they climb over various obstacles without having to look. The amputees report using and feeling their bionic leg as part of their own body, thanks to sensory feedback from the prosthetic leg that is delivered to nerves in the leg's stump. (2019-10-02)

Starting with less-invasive procedures to restore leg blood flow as good at avoiding amputation as starting with open surgery
Patients who underwent a less-invasive procedure to open clogged leg arteries were just a likely to survive with their legs intact as patients who had more invasive surgery. (2019-07-30)

New discovery points toward possible treatment for diabetic non-healing wounds
A new mouse and human tissues study identifies an enzyme critical for normal wound healing that may open up avenues for treatment. (2019-07-23)

Microvascular disease anywhere in the body may be linked to higher risk of leg amputations
Microvascular disease, a disorder of very small blood vessels, may increase the risk of leg amputation independent of other blood vessel conditions and regardless of the location of the microvascular issue, such as eyes (retinopathy), kidneys (nephropathy) or feet (neuropathy). Study participants with both microvascular disease and peripheral arterial disease (PAD) had an almost 23-fold increased risk of amputation compared to those without any vascular disease. (2019-07-08)

Tailor-made prosthetic liners could help more amputees walk again
Researchers at the University of Bath have developed a new way of designing and manufacturing bespoke prosthetic liners, in less than a day. (2019-06-20)

Scientists find new type of cell that helps tadpoles' tails regenerate
Researchers at the University of Cambridge have uncovered a specialised population of skin cells that coordinate tail regeneration in frogs. These 'Regeneration-Organizing Cells' help to explain one of the great mysteries of nature and may offer clues about how this ability might be achieved in mammalian tissues. (2019-05-16)

Low income is a risk factor for 'catastrophic' amputation after knee joint replacement
Above-knee amputation (AKA) is a rare but severe complication of deep infection after knee replacement surgery. Low-income patients are at increased risk of this catastrophic complication, reports a study in Clinical Orthopaedics and Related Research® (CORR®), a publication of The Association of Bone and Joint Surgeons®. The journal is published in the Lippincott portfolio by Wolters Kluwer. (2019-04-30)

Certain strains of bacteria associated with diabetic wounds that do not heal
Whether a wound -- such as a diabetic foot ulcer -- heals or progresses to a worse outcome, including infection or even amputation, may depend on the microbiome within that wound. (2019-04-18)

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