Current Anderson News and Events

Current Anderson News and Events, Anderson News Articles.
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New recommendations aim to eliminate racial bias in myeloma trials
Recommendations designed to address the under-representation of African Americans in clinical trials for multiple myeloma (MM), a blood cancer that is twice as deadly in this demographic as in whites. (2021-02-18)

Study identifies never-before-seen dual function in enzyme critical for cancer growth
In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists aim to identify ways to keep cancer cells from using DNA break repair pathways. New findings demonstrate a previously-unknown capability for polymerase theta (pol theta) - a key enzyme in this repair function - that shows promise as a new avenue for treatment development. (2021-02-11)

How does pain experienced in everyday life impact memory?
A new study conducted out of the University of Miami indicates that brain systems related to emotional distress could underlie the negative impacts of pain on memory in healthy individuals. (2021-02-03)

Mathematical method developed to predict cancer and drug-specific immunotherapy efficacy
Houston Methodist researchers have developed a mathematical model to predict how specific cancers will respond to immunotherapy treatments, thus enhancing chances for successful treatments from a wide variety of cancer-immunotherapy drug combinations. The results were recently published in Nature Biomedical Engineering in collaboration with researchers at MD Anderson Cancer Center. (2021-02-01)

Controlling pain after surgery doesn't have to mean opioids, study shows
As surgeons balance the need to control their patients' post-surgery pain with the risk that a routine operation could become the gateway to long-term opioid use or addiction, a new study shows the power of an approach that takes a middle way. (2021-01-27)

New computational tool reliably differentiates between cancer and normal cells from single-cell RNA-sequencing data
MD Anderson researchers have developed a new computational tool to accurately differentiate between cancer cells and normal cells when analyzing large single-cell RNA-sequencing data. (2021-01-18)

Mediterranean diet may decrease risk of prostate cancer progression
In a study to examine a Mediterranean diet in relation to prostate cancer progression in men on active surveillance, researchers from The University of Texas MD Anderson Cancer Center found that men with localized prostate cancer who reported a baseline dietary pattern that more closely follows the key principles of a Mediterranean-style diet fared better over the course of their disease. (2021-01-07)

Triple chemotherapy combination improves metastatic colorectal cancer outcomes
Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination -- of irinotecan, cetuximab, and vemurafenib -- is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab. (2020-12-23)

Arthritis drug may treat immunotherapy-related heart complication
A drug typically prescribed for rheumatoid arthritis may also be effective in treating a rare but potentially deadly heart complication some cancer patients experience after taking immunotherapies, according to a study published in Cancer Discovery and co-led by investigators at Vanderbilt University Medical Center (VUMC). (2020-12-21)

Financial distress negatively impacts well-being, satisfaction of breast cancer patients
Financial toxicity among breast cancer patients is independently associated with worse psychological well-being following a mastectomy or lumpectomy operation. However, even small improvements in financial pressure associated with treatment-related costs can lead to better mental well-being and higher patient satisfaction with breast reconstruction. (2020-12-11)

Smellicopter: an obstacle-avoiding drone that uses a live moth antenna to seek out smells
A University of Washington-led team has developed Smellicopter: an autonomous drone that uses a live antenna from a moth to navigate toward smells. Smellicopter can also sense and avoid obstacles as it travels through the air. (2020-12-07)

Researchers find 'missing link'
Otago researchers have found the ''missing link between stress and infertility''. (2020-12-03)

Research unlocks new information about reading through visual dictionary in the brain
The uniquely human ability to read is the cornerstone of modern civilization, yet very little is understood about the effortless ability to derive meaning from written words. Scientists at UTHealth have now identified a crucial region in the temporal lobe, know as the mid-fusiform cortex, which appears to act as the brain's visual dictionary. (2020-11-30)

New targeted therapy blocks metabolism in brain cancer cells with genetic vulnerability
Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects. Preclinical studies found the small-molecule enolase inhibitor to be effective in killing brain cancer cells that were missing ENO1, one of two genes encoding the enolase enzyme. (2020-11-23)

New guide on using drones for conservation
Drones are a powerful tool for conservation - but they should only be used after careful consideration and planning, according to a new report. (2020-11-20)

SwRI scientists expand space instrument's capabilities
A new study by Southwest Research Institute scientists describes how they have ex-panded the capabilities of the prototype spaceflight instrument Chemistry Organic and Dating Experiment (CODEX), designed for field-based dating of extraterrestrial materi-als. CODEX now uses two different dating approaches based on rubidium-strontium and lead-lead geochronology methods. The instrument uses laser ablation resonance ionization mass spectrometry (LARIMS) to obtain dates using these methods. (2020-11-16)

New technology allows more precise view of the smallest nanoparticles
Scientists have reported a new optical imaging technology, using a glass side covered with gold nanodiscs that allows them to monitor changes in the transmission of light and determine the characteristics of nanoparticles as small as 25 nanometers in diameter. (2020-11-16)

Pearls may provide new information processing options for biomedical, military innovations
Purdue University innovators are using pearls to provide potential new opportunities for spectral information processing that can be applied to spectroscopy in biomedical and military applications. The Purdue team demonstrated light transport-assisted information processing by creating a pearl spectrometer. (2020-11-13)

MD Anderson researchers present immunotherapy advances at Society for Immunotherapy of Cancer Annual Meeting
Promising clinical results with combination treatments for patients with melanoma and lung cancer highlight immunotherapy advances being presented by researchers from The University of Texas MD Anderson Cancer Center at The Society for Immunotherapy of Cancer (SITC) 35th Anniversary Annual Meeting & Pre-Conference Programs (SITC 2020) . (2020-11-11)

Tel Aviv University says 'environmentally-friendly' tableware harms marine animals
A new Tel Aviv University study compares the effects of two types of disposable dishes on the marine environment -- regular plastic disposable dishes and more expensive bioplastic disposable dishes certified by various international organizations -- and determines that the bioplastic dishes had a similar effect on marine animals as regular plastic dishes. (2020-11-04)

New dataset provides county-level exposure numbers for tropical cyclones, human health
The new open source data set can be used for epidemiological research on tropical cyclones. (2020-10-28)

Inhibition of HDAC and mTOR may improve outcomes for relapsed/refractory Hodgkin lymphoma
The histone deacetylase (HDAC) inhibitor vorinostat (Zolinza) in combination with the mTOR inhibitor sirolimus (Rapamune) or everolimus (Afinitor) showed clinical efficacy in patients with relapsed/refractory Hodgkin lymphoma, according to results from a phase I clinical trial. (2020-10-14)

Dual checkpoint blockade promising as pre-surgical approach for certain patients with localized bladder cancer
Phase I trial finds neoadjuvant combination checkpoint inhibitors (anti-CTLA-4 plus anti-PD-1) was well tolerated and showed early signs of activity in certain patients with bladder cancer. These patients cannot be treated with chemotherapy and have no standard treatment options available. (2020-10-12)

Osteoarthritis biomarker could help 300 million people worldwide
University of South Australia researchers are a step closer to finding a new biomarker for osteoarthritis, a painful condition which affects more than 300 million people worldwide. (2020-10-11)

Study identifies characteristics of infused CAR T cells associated with efficacy and toxicity in in patients with large B-cell lymphoma
Researchers at The University of Texas MD Anderson Cancer Center have identified molecular and cellular characteristics of anti-CD19 CAR T cell infusion products associated with how patients with large B-cell lymphoma (LBCL) respond to treatment and develop side effects. (2020-10-05)

Study finds cancer mutations accumulate in distinct regions based on structure of genome and mutation
A study finds that cancer mutations occur in distinct patterns based on the 3D structure of the genome and the underlying cause of the mutation. This helps us to understand cancer better and may lead to new treatment approaches. (2020-10-05)

Researchers advance COVID-19 antibody knowledge with paper in journal
Researchers at the University of Tennessee Health Science Center working with colleagues at MD Anderson Cancer Center in Houston have found that some antibodies to SARS-CoV-2, the virus that causes COVID-19, are more protective than others, when it comes to reinfection. (2020-10-01)

Genetic differences in body fat shape men and women's health risks
New findings about body fat help explain the differing health risks men and women face - and set the stage for better, more targeted treatments. (2020-09-28)

Discovery of large family of two-dimensional ferroelectric metals
Recently, a team from University of Chinese Academy of Sciences, led by Prof. Gang Su, discovered 16 novel ferroelectric metals from a large family (2,964) of 2D bimetal phosphates via data-driven machine learning and high-throughput first-principle calculations. (2020-09-28)

Next-gen bioinformatics tool enables big data analysis without programming expertise
A new data analysis tool developed by MD Anderson researchers incorporates a user-friendly, natural-language interface to aid biomedical researchers without bioinformatics or programming expertise to conduct intuitive data. (2020-09-24)

KRAS inhibitor sotorasib appears safe, achieves durable clinical benefit in early trial
For patients with advanced solid cancers and KRAS G12C mutations, the targeted therapy sotorasib, a KRAS G12C inhibitor, resulted in manageable toxicities and durable clinical benefits, particularly in lung and colorectal cancer, in Phase I study. (2020-09-20)

New study from MD Anderson and BridgeBio's Navire Pharma shows SHP2 inhibition overcomes multiple therapeutic-resistance mechanisms in lung cancer
New preclinical research from MD Anderson and Navire finds a novel drug targeting SHP2 can overcome multiple paths of therapeutic resistance in lung cancer. Navire will launch a clinical trial of SHP2 inhibitors by the end of 2020. (2020-09-14)

Combination immunotherapy benefits subset of patients with advanced prostate cancer
esults from a Phase II trial led by researchers at MD Anderson Cancer Center suggest that a combination of ipilimumab (anti-CTLA-4) plus nivolumab (anti-PD-1) can generate durable responses in a subset of patients with advanced prostate cancer. (2020-09-10)

Being a selfish jerk doesn't get you ahead, research finds
Two studies provide empirical evidence to settle the question of whether being aggressively Machiavellian helps people get ahead. The studies concluded that being a jerk provides no advantage in career advancement. Any power boost disagreeable people get from being intimidating is offset by their poor interpersonal relationships, the studies concluded. (2020-08-31)

Cardiac biomarker shows stronger associations with kidney disease progression than BP
Identifying biomarkers for kidney disease progression may elucidate disease pathways and inform treatment. In a study of 3,379 adults with kidney disease followed for 12 years (47% with diabetes), elevated levels of N-terminal pro-B-type natriuretic peptide, a cardiac biomarker, were strongly associated with kidney disease progression; associations were stronger than those with systolic blood pressure ?140 mmHg, regardless of heart failure status. These findings highlight the potential role of cardiac disease in kidney disease progression. (2020-08-28)

Lung cancer trial of RET inhibitor selpercatinib achieves durable responses in majority of patients with RET gene fusions
For patients with non-small cell lung cancers marked by RET gene fusions, the targeted therapy selpercatinib was well tolerated and achieved durable objective responses, or tumor shrinkage, in the majority of patients in a Phase I/II trial. (2020-08-26)

Having a doctor who shares the same race may ease patient's angst
When doctors are the same race as their patients, it can sometimes forge a sense of comfort that helps to reduce anxiety and pain, particularly for Black patients, new research from the University of Miami suggests. (2020-08-24)

Mount Sinai study finds COVID patients were most commonly readmitted to hospital for respiratory complications
Study describes characteristics of patients with COVID-19 who returned to the ER or required readmission to the hospital within 14 days of being discharged (2020-08-21)

Firefighters exposed to more potentially harmful chemicals than previously thought
The on-duty firefighters in the Kansas City, Missouri, area experienced higher exposures of polycyclic aromatic hydrocarbons, or PAHs, which are a family of chemicals that are known to have the potential to cause cancer. (2020-08-20)

Targeted therapy combination effective for patients with advanced cholangiocarcinoma and BRAF mutations
In a Phase II trial led by MD Anderson researchers, a combination targeted therapy acheived a 51% overall response rate in patients with cholangiocarcinoma and BRAF V600E mutations. This is the first prospective study for this group of patients. (2020-08-17)

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