Current Aortic Valve News and Events

Current Aortic Valve News and Events, Aortic Valve News Articles.
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This robot doesn't need any electronics
Engineers at the University of California San Diego have created a four-legged soft robot that doesn't need any electronics to work. The robot only needs a constant source of pressurized air for all its functions, including its controls and locomotion systems. The team, led by Michael T. Tolley, a professor of mechanical engineering at the Jacobs School of Engineering at UC San Diego, details its findings in the Feb. 17, 2021 issue of Science Robotics. (2021-02-17)

Endovascular aneurysm repair linked to higher readmission rates
Ruptured abdominal aortic aneurysms (rAAA) are responsible for nearly 2% of all deaths in U.S. men over the age of 65. Endovascular aneurysm repair (EVAR) has emerged as a newer and less invasive alternative to open repair for rAAA. But researchers from the University of Missouri School of Medicine have discovered that while EVAR is more commonly utilized for rAA, the odds of hospital readmission after EVAR are 1.5 times higher compared to traditional open repair. (2021-02-10)

Electronic health records can be valuable predictor of those likeliest to die from COVID
A study by Massachusetts General Hospital identifies key predictors of COVID-19 mortality among different age groups from patient longitudinal medical records. Predictive analytics based on electronic health records could prove valuable in allocating and distributing limited resources in the time of a pandemic. (2021-02-04)

Combining PD-1inhibitor with VEGF inhibitor in chemotherapy of cholangiocarcinoma patient
Cholangiocarcinoma is the second most frequent liver cancer. Many patients miss the opportunity of having a surgery performed on them and its control has always been considered difficult. Here, doctors from The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China, present a case of stage 4 cholangiocarcinoma. (2021-02-02)

'COVID effect' leads to fewer heart surgeries, more patient deaths
The most deadly global health crisis in a century has resulted in a substantial decline in overall heart surgery volume and an unexplained increase in deaths after coronary artery bypass grafting. (2021-01-30)

Breakthrough design at UBCO vastly improves mechanical heart valve
New research coming out of UBC's Okanagan campus may take the current 'gold standard' for heart valves to a new level of reliability. A team of researchers at UBCO's Heart Valve Performance Lab (HVPL) has developed a way to improve overall blood flow through the valves, so the design of mechanical heart valves will more closely match the real thing. (2021-01-26)

Risk factors for intraoperative pressure injury in aortic surgery
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1263, Yao Dong, Jun-E Liu and Ling Song from the Capital Medical University, Beijing, China consider risk factors for intraoperative pressure injury in aortic surgery. (2021-01-22)

Low cost chlorine dispensing device improves tap water safety in low-resource regions
Engineers have developed an inexpensive chlorine dispensing device that improves the safety of drinking water in remote and low resource regions at the point of collection. It requires no electricity and very little maintenance, and provides a quick and easy way to eliminate water borne pathogens. (2021-01-14)

New research reveals early warning sign for heart disease
The build-up of calcium in a major artery outside of the heart could predict future heart attack or stroke, a new Edith Cowan University led study has demonstrated. (2021-01-13)

A potential therapy for one of the leading causes of heart disease
After 15 years of unrelenting work, a team of scientists from Gladstone Institutes has discovered a potential drug candidate for heart valve disease that works in both human cells and animals and is ready to move toward a clinical trial. Their findings were just published in the journal Science. (2020-12-10)

This 3D printer doesn't gloss over the details
A new 3D printing system designed by MIT researchers enables realistic variations in glossiness across a 3D printed surface. The advance could aid fine art reproduction and the design of prosthetics. (2020-12-02)

Scientists solve big limitation of stratospheric balloon payloads
Nearly all photons emitted after the Big Bang are now visible only at far-infrared wavelengths. Earth's atmosphere blocks most of this light, so scientists are turning to huge stratospheric balloons to explore it. However, it is quite difficult to cool a telescope the size of a living room to nearly absolute zero while flying it from a balloon. This is where the Balloon-Borne Cryogenic Telescope Testbed comes in. (2020-12-01)

Scoring system improves screening for "dual" heart disease
Aortic stenosis is one of the most common heart valve defects. As well as conventional valve replacement involving open-heart surgery, a less invasive procedure has now been available for some time in the form of transcatheter aortic valve replacement (TAVR). (2020-11-24)

Implantation of an S-ICD in a patient with a DDD pacemaker and congenitally corrected transposition
Implantation of an S-ICD in a Patient with a DDD Pacemaker and Congenitally Corrected Transposition of the Great Arteries. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0597, Yu Zhang, Wen-Long Dai, Can-Can Lin, Qiao-Yuan Li and Cheng-Jun Guo from Beijing Anzhen Hospital, Capital Medical University, Beijing, China consider implantation of an S-ICD in a patient with a DDD pacemaker and congenitally corrected transposition of the great arteries. (2020-11-19)

TAVR is dominant form of aortic valve replacement, outcomes steadily improving in the US
Since the approval of the first TAVR device in 2011, more than 276,000 patients have undergone a TAVR procedure in the U.S. According to an STS/ACC TVT Registry report, volumes have increased every year and in 2019 TAVR exceeded all forms of SAVR. While 30-day mortality and stroke rates have decreased, pacemaker need remains largely unchanged. The report was published in the Journal of the American College of Cardiology and The Annals of Thoracic Surgery. (2020-11-16)

Rivaroxaban may be as effective as warfarin for bioprosthetic mitral valves, AF
The RIVER trial is the largest study assessing the efficacy and safety of the anticoagulant rivaroxaban in patients with an artificial mitral valve to correct an irregular heart rhythm. Researchers concluded that rivaroxaban worked as well as the standard anticoagulant medication warfarin. (2020-11-14)

Valves on N95 masks do not filter exhaled droplets
Matthew Staymates, fluid dynamicist at the National Institute of Standards and Technology, is studying different mask types to determine which are the most effective at reducing disease transmission. In Physics of Fluids, he describes exploring the basic flow dynamics of N95 masks with or without exhalation valves. To do this, he generates stunning video from his schlieren imaging, a method to visualize the fluid flow away from the surface of an object, and light scattering. (2020-11-10)

New airflow videos show why masks with exhalation valves do not slow the spread of COVID
Using high-speed video and schlieren imaging, NIST researcher Matthew Staymates created videos that show how air flows through masks with and without exhalation valves. 'When you compare the videos side by side, the difference is striking,' Staymates said. 'These videos show how the valves allow air to leave the mask without filtering it, which defeats the purpose of the mask.' (2020-11-10)

New medication may treat underlying causes of hypertrophic cardiomyopathy
Mavacamten, a new investigational cardiac medication, may improve heart function for people with thickened heart muscle leading to obstructed blood flow through the heart, a condition known as obstructive hypertrophic cardiomyopathy. The treatment appears to improve heart structure, reduce cardiac filling pressures (decrease measures of stiffness) and restore normal mitral valve motion. (2020-11-09)

Results from host-reduce-polytech-ACS trial reported at TCT Connect
A randomized clinical trial found that drug-eluting stents (DES) with durable polymers are non-inferior to DES with biodegradable polymers in patients with acute coronary syndrome (ACS). Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine. (2020-10-17)

Rare congenital heart defect rescued by protease inhibition
A research team at the Greenwood Genetic Center (GGC) has successfully used small molecules to restore normal heart and valve development in an animal model for Mucolipidosis II (ML II), a rare genetic disorder. The study is reported in this month's JCI Insight. (2020-10-15)

New bioprosthetic valve for TAVR fails to demonstrate non-inferiority
In a randomized clinical trial, SCOPE II, a new self-expanding bioprosthetic valve used in transcatheter aortic valve replacement (TAVR) failed to demonstrate non-inferiority compared to an existing self-expanding valve. (2020-10-15)

Results from the REFLECT II Trial reported at TCT Connect
The REFLECT II randomized clinical trial evaluating the safety and efficacy of a device designed to reduce cerebral embolization and ischemic stroke, complications of transcatheter aortic valve replacement (TAVR), found that the device met the primary safety endpoint compared to historical controls but did not demonstrate superiority of the device for the primary hierarchical efficacy endpoint. (2020-10-15)

Results from the MITHRAS trial reported at TCT Connect and published in Circulation
The MITHRAS randomized clinical trial found that interventional closure of an iatrogenic atrial septal defect (iASD) driven by transcatheter mitral valve repair (TMVR) was not superior to conservative medical treatment with regard to the primary endpoint of change in six-minute walking distance. (2020-10-15)

Tied to undiagnosed disease, aortic dissection in pregnancy proves difficult to predict
The 100th report out of the International Registry of Acute Aortic Dissection details the experiences of 29 women who faced this rare life-threatening complication while pregnant. (2020-10-14)

Gene expression altered by direction of forces acting on cell
Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few. The type and direction of the force on a cell alters gene expression by stretching different regions of DNA, researchers at University of Illinois Urbana-Champaign and collaborators in China found in a new study. (2020-10-01)

Aortic valve replacement during COVID-19 pandemic
The outcomes associated with deferred compared with expedited aortic valve replacement in patients with severe aortic stenosis during the COVID-19 pandemic are evaluated in this observational study. (2020-09-30)

Patients deferred for transcatheter aortic valve replacement because of COVID-19
This single-center study of 77 patients describes the outcomes of patients with symptomatic severe aortic stenosis during the COVID-19 pandemic. (2020-09-30)

Exosome treatment improves recovery from heart attacks in a preclinical study
Research in pigs shows that using the exosomes naturally produced from a mixture of heart muscle cells, endothelial cells and smooth muscle cells -- which were all derived from human induced pluripotent stem cells -- yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells. (2020-09-29)

New abdominal aortic aneurysm genes identified, could help pinpoint those at risk
A study of US veterans identified 14 genes that may predict the risk of abdominal aortic aneurysm. The related-risk score identifies those at risk regardless of known factors such as smoking or family history. Diastolic blood pressure, the bottom number in a blood pressure reading, may be a better indicator of developing abdominal aortic aneurysm. (2020-09-28)

How earthquake swarms arise
A new fault simulator maps out how interactions between pressure, friction and fluids rising through a fault zone can lead to slow-motion quakes and seismic swarms. (2020-09-24)

Face shield or face mask to stop the spread of COVID-19?
If CDC guidelines aren't enough to convince you that face shields alone shouldn't be used to stop the spread of COVID-19, then maybe a new visualization study will. Researchers simulated coughing and sneezing from a mannequin's mouth using a laser light to visualize droplets expelled. They tested a plastic face shield and found that they block the initial forward motion of the exhaled jet, however, aerosolized droplets are able to move around the visor with relative ease. (2020-09-01)

Study reveals best anti-clotting strategy after heart valve intervention
The POPular TAVI trial has challenged current guideline recommendations on antiplatelet treatment after transcatheter aortic valve implantation (TAVI) in patients not taking oral anticoagulation. The findings are presented in a Hot Line session today at ESC Congress 2020. (2020-08-31)

Research brief: Researchers 3D print lifelike heart valve models
Researchers from the University of Minnesota, with support from Medtronic, have developed a groundbreaking process for multi-material 3D printing of lifelike models of the heart's aortic valve and the surrounding structures that mimic the exact look and feel of a real patient. (2020-08-28)

Steps outlined to reduce the risk of stroke during, after heart surgery
A stroke during or soon after heart surgery, called a perioperative stroke, increases the risk of death and can result in major disability for survivors. Stroke is one of the most feared complications of heart surgery. In general, the risk of stroke during or after heart surgery is low. However, pre-screening, measures taken during surgery, and immediate diagnosis and treatment of a stroke can improve patient survival and quality of life. (2020-08-26)

Computational modeling enables heart valve visualizations
Computational modeling has provided new insights into the heart's vascular system, a complex and mechanically demanding system that remains poorly understood. (2020-08-05)

Engineers find thinner tissues in replacement heart valves create problematic flutter
Iowa State and University of Texas engineers have developed high-fidelity computational models of replacement heart valves to examine the performance of biological tissues built into the valves. They found that thinner tissues can flap and flutter, which can damage the valves and even the blood that flows by. (2020-07-29)

Invention offers new option for monitoring heart health
A team from Purdue University developed self-powered wearable triboelectric nanogenerators (TENGs) with polyvinyl alcohol (PVA)-based contact layers for monitoring cardiovascular health. TENGs help conserve mechanical energy and turn it into power. (2020-07-22)

Diagnosing acute aortic syndrome: New guideline for hard-to-diagnose condition
A new guideline aimed at helping clinicians identify the difficult-to-diagnose acute aortic syndrome is published in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/lookup/doi/10.1503/cmaj.200021. (2020-07-20)

Hyperactive immune cells accelerate heart valve disease: Study
Aortic valve stenosis is the most common type of heart valve disease in the elderly and affects more than one in eight people aged over 75. Researchers used organ-on-a-chip technology to discover the disease is made worse by the damaging hyperactivity of immune cells, which are activated by the constant stress of squeezing through the narrow aortic valve. (2020-07-08)

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