Current Approach News and Events

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New approach to design functional antibodies for precision vaccines
A new approach to de novo protein design dubbed 'TopoBuilder' allows researchers to develop complex antigens that, when used in vaccines, elicit antibody responses that target the weaknesses in some of the most intractable viral pathogens, including respiratory syncytial virus (RSV). (2020-05-14)

Counting the uncounted
Though abundance is a fundamental measure in ecology and environmental management, detecting all individuals in a population is usually impossible when monitoring, so estimates of abundance must account for imperfect detection. (2019-06-06)

Infinite number of quantum particles gives clues to big-picture behaviour at large scale
In quantum mechanics, measuring both the position and speed of a particle at the same time is not possible. To identify a particle's characteristics, physicists introduced the notion of quasi-distribution of position and momentum. In a new study published in EPJ ST, Dr J.S. Ben-Benjamin and colleagues from Texas A&M University, USA, reverse this approach; starting with quantum mechanical rules, they explore how to derive an infinite number of quasi-distributions, to emulate the classical mechanics approach. (2019-04-11)

Novel approach to making therapeutic proteins at point of care
A novel approach to making therapeutic proteins allows medicine to be developed in a suitcase-size system. (2018-07-10)

Game-changing finding pushes 3D-printing to the molecular limit
New University of Nottingham research proves that advanced materials containing molecules that switch states in response to environmental stimuli such as light can be fabricated using 3D printing. The study findings have the potential to vastly increase the functional capabilities of 3D-printed devices for industries such as electronics, healthcare and quantum computing. (2018-06-19)

Undersea fiber optics: A new way to detect quakes
Monitoring earthquake-induced changes in fiber optic cables on the ocean floor represents a new way to detect quakes, researchers say. (2018-06-14)

Nanomedicine -- Targeting cancer cells with sugars
Globally, cancer is the second leading cause of death, also because the efficiency of chemotherapeutics is inadequate due to poor delivery to the tumor. Prof Olivia Merkel and her team develop targeted nanocarrier systems to increase the delivery rates of therapeutic formulations and their specific uptake into the target cells. (2018-05-14)

Discontinuity of care puts older patients at higher risk of emergency hospitalization
Discontinuity of care puts older patients at higher risk of emergency hospitalization. (2017-11-15)

Health policy expert to study electronic sharing of health information in primary care
The Agency for Healthcare Research and Quality has awarded a grant to a health and policy management expert at the Richard M. Fairbanks School of Public Health at Indiana University-Purdue University Indianapolis to study for the first time the use and effectiveness of alternative methods of electronically sharing information in primary care settings. (2016-10-13)

New approach may be key to improving US population health
The United States spends more on health care than any other country in the world, yet the life expectancy of its citizens is significantly shorter when compared to other high-income countries. Now, researchers at the University of Missouri School of Medicine are suggesting that an innovative systems-thinking approach to population health could improve the country's current health disadvantage. (2016-10-11)

UBC research could help local governments plan together
A new approach to modelling land use change developed at UBC could help cities and towns better coordinate their land-use planning efforts. The approach can enhance existing computer planning models, better enabling planners to consider how the land-use patterns of their neighbors could impact planning in their own communities. (2016-09-08)

Anterior vs. posterior: Does surgical approach impact hip replacement outcomes?
The surgical approach to total hip replacement -- either from the front of the body or the side/back (anterior vs. posterior) -- has no impact on outcomes six months after surgery, according to research presented today at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons. (2016-03-03)

Christmas cracker pulling: How to send everyone home a winner
According to experts' statistical analyses, if you're expecting 10 guests for dinner on Christmas day, 15 crackers -- those festive cardboard tubes filled with a one-size-fits-no-one paper hat, a small toy, and a groan-inducing joke -- should be enough to send everyone home happy. The experts came to their estimation by simulating 10,000 parties, with guest numbers ranging from two to 50. Their results are published in Significance. (2014-12-15)

Advocating weight diversity
A new review of the way health-care professionals emphasize weight to define health and well-being suggests the approach could be harmful to patients. (2014-10-07)

Back away, please
According to University of Chicago Booth School of Business Professor Christopher K. Hsee, we still have negative feelings about things that approach us -- even if they objectively are not threatening. (2014-06-23)

Cops on the street: How many are needed?
A Michigan State University criminologist has created a research-based approach to police staffing and allocation that could ultimately improve police work for agencies stretched thin by layoffs and expanding police roles. (2012-10-24)

Workplace exposure to organic solvents linked to heart defects at birth
Workplace exposure to organic solvents is linked to several types of heart defects at birth, indicates research published online in Occupational and Environmental Medicine. (2012-07-17)

Researchers boost efficiency of multi-hop wireless networks
Multi-hop wireless networks can provide data access for large and unconventional spaces, but they have long faced significant limits on the amount of data they can transmit. Now researchers from North Carolina State University have developed a more efficient data transmission approach that can boost the amount of data the networks can transmit by 20 to 80 percent. (2012-04-19)

'Evolution: A Developmental Approach'
What separates humans from Chimpanzees? Is it the genetics of our population, or our different structures and behavior capabilities? To Professor Wallace Arthur it is all of these points, which is why his latest book (2011-01-27)

40-year-old test procedure finds modern niche in developing new medicines
The blood test procedure used on newborn infants for 40 years is finding a second life in the search for new lifesaving medications, according to an article in the current edition of Chemical & Engineering News, ACS' weekly newsmagazine. (2011-01-19)

Combinatorial therapy allows viruses to destroy tumors
For several years, researchers have been developing a new approach to treating cancer that uses viruses to infect and kill cancer cells while leaving normal cells unharmed. New research indicates that this approach, which is known as oncolytic virotherapy, can be combined with a standard clinical therapy to provide substantial regression and cure of tumors in mice, leading to the suggestion that this combinatorial approach could be of tremendous benefit in the clinic. (2010-04-01)

A primer on aspirating breast lumps
A patient with a breast lump that has no features suggesting cancer should still be immediately evaluated, according to a primer for physicians in CMAJ. (2010-03-01)

MSU researcher advocates new way to treat autism
Children with autism would likely receive better treatment if supporters of the two major teaching methods stopped bickering over theory and focused on a combined approach, a Michigan State University psychologist argues in a new paper. (2010-01-28)

High-blood-pressure treatment for the over-80s too aggressive, warns expert
People over 80 years are being treated too aggressively for high blood pressure, warns an expert in an editorial in BMJ Clinical Evidence this week. (2009-12-22)

Unified approach to premature infant care improves patient outcomes
A substantial number of premature infants born before 27 weeks gestational age encounter complicated medical problems. Although the survival rate of these infants has increased over the last two decades, the survival data for these patients is highly variable. (2009-12-01)

Cuba's maternal health and early childhood development: Lessons for Canada
Cuba's comprehensive approach to maternal health and early childhood development can be a model for Canada, writes Dr. Wilbert Keon, chair of Canada's Senate Subcommittee on Population Health in an analysis in CMAJ. (2009-02-02)

U of M researchers discover new method to combat HIV
Researchers at the University of Minnesota's Center for Drug Design, have developed a new method to combat HIV/AIDS, potentially replacing the traditional cocktail drug approach. (2007-07-23)

Research ethics requirements compromising quality of health research
Current research ethics requirements are compromising the scientific quality of health research, warn senior doctors in this week's BMJ. Many ethics committees now insist that researchers approach only people who respond positively to a letter from their doctor informing them about an opportunity to take part in research -- that is, people must opt in to being contacted by a researcher. (2006-08-03)

First steps taken towards made-in-Canada approach
The Government of Canada is putting in place a made-in-Canada plan for reducing greenhouse gases (GHG) and ensuring clean air, water, land and energy for Canadians. As part of developing the made-in-Canada approach, 15 programs that have completed their work or which require a different approach are being wound down. (2006-04-13)

HIV prevention schemes neglect partner reduction
Without multiple sexual partnerships there would be no global AIDS pandemic, yet partner reduction is still overlooked in most HIV prevention programmes, argue researchers in this week's BMJ. (2004-04-08)

Roll Up Your Sleeves And Join Us In The Field, Says Fish And Wildlife Service To Conservation Biologists
When conservation biologists said resource managers should consider entire ecosystems rather than focusing on single species, U.S. Fish and Wildlife Service director Jamie Rappaport Clark challenged her agency to pioneer the ecosystem approach. Now she challenges conservation biologists to help them implement it. (1999-05-26)

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