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Current Arthritis News and Events, Arthritis News Articles.
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Study: Why people with knee osteoarthritis experience different kinds of pain
People with more pain sensitization were more likely to suffer from constant and unpredictable pain, rather than just intermittent pain. This study has identified for the first time a potential underlying mechanism in the nervous system responsible for why people experience varying pain patterns with knee osteoarthritis. (2020-09-04)

Heart disease signs improve when using arthritis medication
Drugs used to treat initial signs of rheumatoid arthritis also improve the early stages of heart disease, according to new research (2020-09-02)

New analysis shows hydroxychloroquine does not lower mortality in COVID-19 patients, and is associated with increased mortality when combined with the antibiotic azithromycin
A new meta-analysis of published studies into the drug hydroxychloroquine shows that it does not lower mortality in COVID-19 patients, and using it combined with the antibiotic azithromycin is associated with a 27% increased mortality. The study is published in Clinical Microbiology and Infection. (2020-08-26)

Most adults with lupus or common types of arthritis have similar risks of getting admitted to hospital as other COVID-19 patients
Most adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to dampen their altered immune system, the cause of their disease. (2020-08-25)

Lab-created molecule achieves positive results in the treatment of arthritis
Tested in mice with genetically induced arthritis, the substance decreased the area affected, reduced local swelling, and assuaged the pain associated with the inflammatory process. (2020-08-11)

Change isn't a good thing for Japanese rheumatoid arthritis patients
Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) that dramatically increases the risk of death. In a recent study led by Osaka University, researchers identified a genetic variant that increases the risk of ILD among Japanese RA patients, most likely by altering the expression of the RPA3 gene and triggering scarring of lung tissue. Identifying risk variants associated with RA-ILD will help unravel the underlying causes of disease in different populations. (2020-08-09)

Rheumatoid arthritis linked to a lower risk of type 2 diabetes
A recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other individuals, including those with other types of arthritis. (2020-08-05)

Gout diagnoses rising worldwide
The prevalence of gout -- a form of arthritis characterized by severe pain, redness, and tenderness in joints--increased across the world at an alarming rate from 1990 to 2017, according to an analysis published in Arthritis & Rheumatology. (2020-08-05)

Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. Researchers have now identified certain lung-related factors that may help to predict an individual smoker's fracture risk. The findings are published in the Journal of Bone and Mineral Research. (2020-08-05)

Bone drug may be beneficial for knee osteoarthritis
Bisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear to be safe and beneficial for osteoarthritis patients. (2020-08-05)

BU study: A quarter of arthritis cases linked to excess weight
A new Boston University School of Public Health (BUSPH) study shows that weight loss between early adulthood and midlife lowers arthritis risk, and found no evidence of any persistent risk of arthritis for people who were heavier earlier in life and then lost weight. (2020-08-04)

Reducing corticosteroid use in rheumatoid arthritis
Is the long-term use of glucocorticoids essential in people with chronic inflammatory diseases such as rheumatoid arthritis, or can early discontinuation prevent characteristic side effects? How can these drugs be discontinued without giving rise to glucocorticoid withdrawal syndrome? These were the questions addressed by the SEMIRA study, a large European trial led by Charité - Universitätsmedizin Berlin. (2020-07-31)

COVID-19: Patients improve after immune-suppressant treatment
Most patients hospitalized with COVID-19 (coronavirus) pneumonia experienced improvement after receiving a Food and Drug Administration-approved drug normally given for rheumatoid arthritis, according to an observational study at Cedars-Sinai. Outcomes for patients who received the drug, tocilizumab, included reduced inflammation, oxygen requirements, blood pressure support and risk of death, compared with published reports of illness and death associated with severely ill COVID-19 patients. (2020-07-15)

Significantly less addictive opioid may slow progression of osteoarthritis while easing pain
A Keck Medicine of USC study reveals that kappa opioids, a significantly less addictive opioid, may preserve cartilage in joints and ease pain (2020-07-13)

Total-body PET/CT captures full picture of systemic inflammatory arthritis
For the first time, physicians can examine the systemic burden of inflammatory arthritis simultaneously across all joints and organ systems, using the high-sensitivity, high-resolution uEXPLORER total-body positron emission tomography/computed tomography (TB-PET/CT) scanner. Results of the first in-human TB-PET/CT scans conducted in the arthritic population were presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Virtual Annual Meeting. (2020-07-11)

Salmonella biofilm protein causes autoimmune responses -- Possible link with Alzheimer's
Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac) at the University of Saskatchewan (USask) and Temple University (Philadelphia, US) have demonstrated that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals. (2020-07-09)

Certain jobs linked to higher risk of knee osteoarthritis
Workers in jobs that typically involve heavy lifting, frequent climbing, prolonged kneeling, squatting, and standing face an increased risk of developing knee osteoarthritis. That's the conclusion of a new analysis published in Arthritis Care & Research. (2020-07-08)

New trial results question standard treatment plan for rheumatoid arthritis
In a clinical trial of patients with rheumatoid arthritis, treatment with a drug called upadacitinib provided greater benefits than methotrexate, the most commonly used initial therapy for rheumatoid arthritis. (2020-07-08)

Rheumatoid arthritis patients under treatment with methotrexate
Patients with rheumatoid arthritis (RA) often suffer from what is referred to as interstitial lung disease (ILD). For years, standard medication with Methotrexate (MTX) has been suspected of either increasing the risk of, or worsening, this aspect of rheumatoid arthritis. This suspicion is now refuted by two current studies. The results have been presented at the annual conference of the European League Against Rheumatism (EULAR 2020). (2020-07-07)

EULAR: Early and intensive treatment of rheumatoid arthritis reduces fatigue
Disease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian study (1) has now concluded that early intensive treatment combining methotrexate with a bridging scheme of prednisone can reduce the onerous fatigue. European League against Rheumatism (EULAR) therefore recommends, that even in so-called low-risk patients, early consideration should be given to whether intensive treatment should be initiated. (2020-06-17)

Shift to online consultations helps patients with chronic pain receive support in lockdown
Academics and practitioners from the Centre for Pain Research at the University of Bath (UK) have been active in ensuring those with debilitating chronic pain conditions continue to receive support throughout lockdown, including by championing virtual consultations. (2020-06-11)

Improved MRI scans could aid in development of arthritis treatments
An algorithm which analyses MRI images and automatically detects small changes in knee joints over time could be used in the development of new treatments for arthritis. (2020-06-09)

EULAR advocates deployment of health care professionals -- study confirms effectiveness
Inflammatory-rheumatic disorders are a widespread ailment, affecting at least 1.5 million people in Germany alone. Because of the shortage of rheumatologists, however, only half of the patients are adequately treated (1,2). A study in Germany has shown for the first time that the care of patients with inflammatory-rheumatic diseases by 'rheumatological assistants' (RFA*) is just as effective as treatment by specialist rheumatologists. (2020-06-09)

Case Western Reserve-led research uncovers connections between psoriasis and joint disease
A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure. (2020-06-08)

EULAR 2020: Thrombosis risk particularly high for people suffering
People suffering from rheumatoid arthritis with increased disease activity are more often affected by thrombosis. (2020-06-05)

BIOCAD presents results of clinical trial proving efficacy of netakimab at EULAR 2020
BIOCAD presents results of clinical trial proving efficacy of netakimab in the treatment of psoriatic arthritis at the Annual European Congress of Rheumatology (EULAR 2020). Four abstracts present the results from an international randomized double-blind phase 3 clinical trial (PATERA) which demonstrate netakimab decreases disease activity and reduces skin manifestation of psoriatic arthritis through 24 weeks of therapy. (2020-06-04)

New test method can offer safer dosages of hydroxychloroquine
Researchers at Uppsala University and Uppsala University Hospital have developed a new method to measure levels of the medication hydroxychloroquine in patients with the rheumatic disease systemic lupus erythematosus (SLE). The analysis method may also be useful in other areas, such as in the treatment of COVID-19. The study is being published in Arthritis Research and Therapy. (2020-06-01)

New effective treatment for inflammatory diseases found
New research conducted by the University of Liverpool and AKL Research and Development Ltd (AKLRD), published in Inflammopharmacology, highlights the potential benefits of a new drug treatment on the human body's immune response in inflammation. (2020-06-01)

Researchers find CBD improves arthritis symptoms in dogs
This study shows that in dogs diagnosed with arthritis, CBD treatment significantly improved quality of life as documented by both owner and veterinarian assessments. (2020-05-28)

Study finds surge in hydroxychloroquine/chloroquine prescriptions during COVID-19
A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic. (2020-05-28)

Excess coffee consumption a culprit for poor health
Cappuccino, latte or short black, coffee is one of the most commonly consumed drinks in the world. But whether it's good or bad for your health can be clarified by genetics, as a world-first study from the University of South Australia's Australian Centre for Precision Health shows that excess coffee consumption can cause poor health. (2020-05-13)

EULAR 2020
Breast cancer patients don`t have an increased risk of developing rheumatoid arthritis. (2020-05-13)

Gene therapy in mice builds muscle, reduces fat
Researchers at Washington University School of Medicine in St. Louis found that gene therapy in mice helped build strength and significant muscle mass quickly, while reducing the severity of osteoarthritis. The gene therapy also prevented obesity, even when the mice were fed a high-fat diet. (2020-05-08)

Rheumatoid arthritis patients on medicare seeing increased costs for specialty medications
After a sharp drop in out-of-pocket costs between 2010 and 2011, Medicare patients who use specialty biologic medications for rheumatoid arthritis have seen higher out-of-pocket spending for those same drugs because of gradual price increases, a new study in the Journal of the American Medical Association Open finds. (2020-05-01)

Cracking the Lyme disease code
The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn't linger for a lifetime. (2020-04-30)

New clinical review casts doubt on use of chloroquine and hydroxychloroquine for COVID-19
In its May issue, The FASEB Journal is publishing a comprehensive review on the science and clinical experiences with the drugs chloroquine and hydroxychloroquine, first introduced as effective weapons against malaria, rheumatoid arthritis, and the autoimmune disease lupus. Recent anecdotal reports suggested these drugs might be effective against the SARS-CoV-2 virus, the cause of the COVID-19 pandemic. This new review describes the growing skepticism regarding adoption of chloroquine and hydroxychloroquine for the respiratory infection caused by this virus. (2020-04-30)

Light helps arthritis treatments target joints
Results from a new mouse study suggest that a new light-activated drug delivery method helps confine treatments to the joints, which could reduce whole-body side effects. (2020-04-27)

Is autoimmunity on the rise?
A study published in Arthritis & Rheumatology provides evidence that the prevalence of autoimmunity -- when the immune system goes awry and attacks the body itself -- has increased in the United States in recent years. (2020-04-08)

A protein that controls inflammation
A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis. They discovered how the protein A20 prevents inflammation and autoimmunity, not through its enzymatic activities as has been proposed, but through a non-enzymatic mechanism. (2020-03-17)

Lung diseases linked to higher rheumatoid arthritis risk
Asthma and chronic obstructive pulmonary disease (COPD) were each associated with increased risk for developing rheumatoid arthritis in a study published in Arthritis & Rheumatology. (2020-03-04)

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