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Current Arthritis News and Events, Arthritis News Articles.
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Drug halts organ damage in inflammatory genetic disorder
A new study shows that Kineret (anakinra), a medication approved for the treatment of rheumatoid arthritis, is effective in stopping the progression of organ damage in people with neonatal-onset multisystem inflammatory disease. This rare and debilitating genetic disorder causes persistent inflammation and ongoing tissue damage. The research was performed by scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health. (2012-02-10)

Henry Ford Hospital researchers identity potential biomarker for osteoarthritis
Henry Ford Hospital researchers have identified for the first time two molecules that hold promise as a biomarker for measuring cartilage damage associated with osteoarthritis. Researchers say the concentration of two molecules called non-coding RNAs in blood were associated with mild cartilage damage in 30 patients who were one year removed from reconstruction surgery to repair an anterior cruciate ligament, or ACL, injury. (2012-02-04)

Poor neighborhoods suffer higher incidence of arthritis
People living in poor neighborhoods have a higher rate and risk of arthritis - one of the most common causes of disability in the developed world. (2012-01-31)

Lumbar disc degeneration more likely in overweight and obese adults
One of the largest studies to investigate lumbar spine disc degeneration found that adults who are overweight or obese were significantly more likely to have disc degeneration than those with a normal body mass index. Details of this study now appear in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology. (2012-01-30)

Steroids prevent protein changes seen in the joints of people with rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease where the body begins to attack the joints and organs of the body. Proteins within inflamed joints are often modified by citrullination. New research published in BioMed Central's open-access journal Arthritis Research & Therapy shows that glucocorticoid therapy can reduce the amount of citrullination and the amount of the enzyme peptidylargininedeiminase 4 responsible for citrullination in the joints of people with RA. (2012-01-26)

2 in 5 adults with rheumatoid arthritis are physically inactive
A new study, funded by a grant from the National Institute for Arthritis and Musculoskeletal and Skin Diseases, found that two in five adults with rheumatoid arthritis (RA) were inactive. Taking measures to motivate RA patients to increase their physical activity will improve public health according to the findings now available in Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology. (2012-01-26)

System to deliver organ transplant drug -- without harmful side effects
A new system for delivering a drug to organ transplant patients, which could avoid the risk of harmful side effects, is being developed by scientists at the University of Strathclyde in Glasgow, Scotland. (2012-01-26)

New medication, surgery may offer relief for patients with psoriatic arthritis
Medications or biologic agents that target T-cells, white blood cells involved in the body's immune system, appear to offer significant benefit to patients suffering from psoriatic arthritis, a type of arthritis that affects up to 48 percent of patients with the skin disease psoriasis, according to a new review article in the Journal of the American Academy of Orthopaedic Surgeons. (2012-01-18)

Muscle relaxants and neuromodulators for managing RA pain: Many options, but no clear successes
Pain management is a high priority for patients with rheumatoid arthritis, so three researchers in Australia analyzed existing study data to see whether two different classes of drugs can help. When looking at muscle relaxants, they discovered that neither the benzodiazepine agents, diazepam and triazolam, nor the non- benzodiazepine agent, zopiclone, reduce pain when taken for one to 14 days. However, even this short use was associated for both agents with drowsiness and dizziness. (2012-01-17)

Knee replacement surgery incidence soars in those over age 50
Researchers in Finland found that annual cumulative incidences of partial and total knee arthroplasty, commonly known as knee replacement surgery, rose rapidly over a 27-year period among 30- to 59-year-olds in that country, with the greatest increase occurring in patients aged 50 to 59 years. According to the study published today in Arthritis & Rheumatism, a peer-reviewed journal of the American College of Rheumatology, incidences were higher in women throughout the study period. (2012-01-17)

Ultra short telomeres linked to osteoarthritis
Telomeres, the very ends of chromosomes, become shorter as we age. New research published in BioMed Central's open-access journal Arthritis Research & Therapy shows that cells from osteoarthritic knees have abnormally shortened telomeres and that the percentage of cells with ultra short telomeres increases the closer to the damaged region within the joint. (2012-01-15)

NIH study shows 32 million Americans have autoantibodies that target their own tissues
More than 32 million people in the United States have autoantibodies, which are proteins made by the immune system that target the body's tissues and define a condition known as autoimmunity, a study shows. The first nationally representative sample looking at the prevalence of the most common type of autoantibody, known as antinuclear antibodies (ANA), found that the frequency of ANA is highest among women, older individuals, and African-Americans. (2012-01-13)

UofL researcher earns the Foundation for Polish Science Prize
The findings of Jan Potempa, Ph.D., D.Sc., professor and academic scholar, Oral Health and Systemic Disease group, University of Louisville School of Dentistry, have helped change scientific thinking about the origin of periodontal tissue inflammation. (2012-01-13)

NIH scientists identify novel approach to view inner workings of viruses
Researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, have developed a new way to see structures within viruses that were not clearly seen before. Their findings are reported in the Jan. 13 issue of Science. (2012-01-12)

First step toward treatment for painful flat feet
A team led by the University of East Anglia has made an advance in understanding the causes of adult-acquired flat feet -- a painful condition particularly affecting middle-aged women. (2012-01-11)

Clinical trial demonstrates that rilonacept significantly reduces gout flares
A phase II clinical trial found that rilonacept, an inhibitor of the protein interleukin-1, significantly reduced acute gout flares that occur when initiating uric acid-lowering therapy. Results of the trial -- the first placebo-controlled study investigating IL-1 targeted therapy in prevention of gout flares -- show rilonacept to be generally well tolerated with no serious infections or treatment-related serious adverse events reported. Full findings are published in Arthritis & Rheumatism, a journal of the American College of Rheumatology. (2012-01-05)

Knee pain common complaint in middle-aged and mature women
New research shows 63 percent of women age 50 and older reported persistent, incident, or intermittent knee pain during a 12-year study period. Predictors for persistent pain included higher body mass index, previous knee injury, and radiographic osteoarthritis. Details of this longitudinal study are available in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology. (2011-12-19)

Walking skills program improves physical function following hip replacement surgery
Researchers in Norway report that patients who receive walking skills training following total hip arthroplasty for osteoarthritis show improved physical function. The physical therapy program displayed a positive effect on walking distance and stair climbing which continued 12 months following hip replacement surgery. Results of the study appear in Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology. (2011-12-15)

Chief scientific officer named first Richard L. Menschel Research Chair at Special Surgery
Steven R. Goldring, M.D., chief scientific officer, has been named the first Richard L. Menschel Research Chair at Hospital for Special Surgery in New York City. A gift of $5 million from an anonymous donor will permanently endow the position of the Hospital's chief scientific officer. (2011-12-13)

Bilateral oophorectomy associated with higher prevalence of low bone mineral density and arthritis in younger women
Women who underwent surgery to remove their ovaries before the age of 45 years were more likely to have arthritis and low bone mineral density compared with women with intact ovaries, researchers found. (2011-12-08)

Increased risk of blood clots on the lung for patients with autoimmune diseases
In a nationwide study based on data from the in-patient register, researchers have studied the risk of a blood clot on the lung for patients with autoimmune diseases such as rheumatoid arthritis, inflammatory bowel disease and Type 1 diabetes. The study showed that 31 of the 33 autoimmune diseases studied were associated with an increased risk of pulmonary embolism -- a blood clot on the lung. (2011-11-28)

Patients with a wide range of autoimmune disorders have much greater risk of pulmonary embolism, and prophylaxis could be warranted
When patients have been admitted to hospital for an autoimmune disorder, they have a much greater risk of having a pulmonary embolism during the following 12 months. Thus prophylaxis could be warranted in these patients. (2011-11-25)

Psychological intervention reduces disability and depression in adolescents with fibromyalgia
A recent trial shows cognitive-behavioral therapy reduces functional disability and depressive symptoms in adolescents with juvenile fibromyalgia. The psychological intervention was found to be safe and effective, and proved to be superior to disease management education. Full findings from this multi-site clinical trial are published in Arthritis & Rheumatism, a peer-reviewed journal of the American College of Rheumatology. (2011-11-22)

Rheumatologists update assessments for adult pain
Assessment of patient outcomes allows physicians and researchers to measure the success or failure of diagnostics and treatments that patients receive. One set of measurement tools focuses on assessing adult pain and is included in a special issue of Arthritis Care & Research, a journal of the American College of Rheumatology, providing physicians and researchers with a single resource of 250 patient outcomes measurements in rheumatology. (2011-11-16)

Talking therapy over the phone improves symptoms of chronic widespread pain
Talking therapy provided over the phone can have a positive impact on people suffering from chronic widespread pain compared to usual care provided by their GP, new research has shown. (2011-11-14)

Poor sleep habits linked to increased risk of fibromyalgia in women
Researchers from Norway have uncovered an association between sleep problems and increased risk of fibromyalgia in women. The risk of fibromyalgia increased with severity of sleep problems, and the association was stronger among middle-aged and older women than among younger women. Results of the prospective study, based on ten years of data, appear in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology. (2011-11-14)

Telephone-based therapy and exercise appear effective for reducing chronic widespread pain
Telephone-delivered cognitive behavioral therapy and an exercise program, both separately and combined, are associated with short-term positive outcomes for patients with chronic widespread pain, and may offer benefits for patients diagnosed with fibromyalgia, according to a report published online first by Archives of Internal Medicine, one of the JAMA/Archives journals. (2011-11-14)

Studies explore new approaches to treating pain
Scientists are discovering promising approaches to treating pain, one of the most common and debilitating neurological complaints, according to research released today at Neuroscience 2011, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health. (2011-11-14)

Study helps eliminate causes for joint pain linked to commonly used breast cancer drugs
Researchers exploring why some women who take a common breast cancer drug develop serious joint pain have eliminated two possible causes: Inflammatory arthritis and autoimmune disease. Because of these findings, researchers say women should be encouraged to continue taking the medication to gain its full benefit. (2011-11-11)

Steven B. Abramson, MD, receives distinguished Basic Investigator Award at ACR 2011
Steven B. Abramson, MD, senior vice president and vice dean of education, faculty and academic affairs and professor, Departments of Medicine and Pathology at NYU Langone Medical Center received the Distinguished Basic Investigator Award at the American College of Rheumatology & Association of Rheumatology Health Professionals annual scientific meeting this week in Chicago. (2011-11-07)

Most lupus nephritis patients with end-stage renal disease opt for hemodialysis therapy
Newly published research shows that more patients with end-stage renal disease caused by lupus nephritis choose hemodialysis as their initial kidney replacement therapy over peritoneal dialysis and preemptive kidney transplantation. Results of the study now available in Arthritis Care & Research, a journal of the American College of Rheumatology, also found that African-Americans, Medicaid recipients, those without health insurance, and the unemployed had significantly reduced initiation of peritoneal dialysis. (2011-11-07)

Rheumatoid arthritis patients have low expectations after knee replacement surgery
Compared with osteoarthritis patients, individuals with rheumatoid arthritis who undergo total knee replacement surgery have lower expectations about their post-surgical outcomes, according to a new study by researchers at Hospital for Special Surgery. These reduced expectations, which may be unnecessary, could cause some patients to slack on their post-surgical rehabilitation leading to worse outcomes, say doctors. (2011-11-05)

Mayo Clinic: Young women with rheumatoid arthritis at more risk for broken bones
Women under 50 with rheumatoid arthritis are at greater risk of breaking bones than women without the condition, according to a Mayo Clinic study being presented at the American College of Rheumatology annual scientific meeting in Chicago. (2011-11-05)

NYU Langone experts present at American College of Rheumatology 2011 Annual Meeting
Experts from NYU Langone Medical Center will present new research findings and clinical insight into the treatment of rheumatic and bone diseases in a variety of presentations at the American College of Rheumatology 2011 Annual Scientific Meeting in Chicago, Nov. 5-9, 2011. (2011-11-04)

Dead of winter is tough on arthritis sufferers
As cold winter weather sets in and daylight hours dwindle, many older Chicagoans with arthritis tend to sit idle, missing out on the daily dose of physical activity they need to improve their health, according to a Northwestern Medicine study. (2011-11-04)

Researchers find molecule that prevents Type 1 diabetes in mice
Researchers at the University of Colorado School of Medicine have found a molecule that prevents Type 1 diabetes in mice. (2011-10-31)

Statin therapy fails to slow progression of atherosclerosis in pediatric lupus patients
Atorvastatin therapy was found to be ineffective in reducing atherosclerosis progression in children and adolescents with systemic lupus erythematosus (SLE). Results of the Atherosclerosis Prevention in Pediatric Lupus Erythematosus Trial, now available in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology, report that the statin therapy did trend toward positive effect of treatment and may benefit patients with more severe SLE who were not included in the trial. (2011-10-27)

NIH study shows benefits, limits of therapy for rare inflammatory syndrome
A study shows that the medication etanercept reduces the frequency and severity of symptoms of TNF receptor-associated periodic syndrome, a rare inherited condition characterized by recurrent fevers, abdominal pain and skin rashes. The study, published in Arthritis & Rheumatism, also points out the need for the development of additional therapies to more thoroughly ease symptoms and prevent long-term complications of the disease. (2011-10-25)

More African-Americans burdened by osteoarthritis in multiple large joints
New research suggests African-Americans have a higher burden of multiple, large-joint osteoarthritis (OA), and may not be recognized based on the current definition of (2011-10-21)

Omega-3 fatty acids shown to prevent or slow progression of osteoarthritis
New research has shown for the first time that omega-3 in fish oil could (2011-10-17)

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