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Current Aspirin News and Events, Aspirin News Articles.
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USPSTF urges patients and doctors to discuss aspirin therapy
The U.S. Preventive Services Task Force (USPSTF) today strongly recommended that doctors discuss the benefits and harms of aspirin therapy with adult patients who are at increased risk of coronary heart disease (CHD). (2002-01-14)

Over 40,000 lives lost worldwide every year
The 'humble' aspirin, which has been known for at least a decade to prevent heart attacks and strokes in thousands of people at high risk of cardiovascular disease, is still massively underused, according to new UK research published (Friday Jan 11) in the British Medical Journal. (2002-01-10)

Aspirin protects patients at high risk of heart attack or stroke
Aspirin (or another antiplatelet drug) protects patients at high risk of serious vascular events, such as heart attack or stroke, and should be considered routinely for all such patients, concludes a study in this week's BMJ. (2002-01-10)

Ibuprofen blocks aspirin's ability to protect against heart attacks
The ibuprofen that you take to ease arthritis pain can counteract the aspirin that you take to protect your heart. The researchers were looking to see how aspirin, taken to prevent second heart attacks, interacts with nonsteroidal anti-inflammatory drugs (NSAIDs), which includes ibuprofen, commonly taken to treat rheumatoid arthritis. (2001-12-19)

Aspirin appears to reduce stroke severity
Individuals who had taken at least one aspirin in the week before suffering an ischemic stroke had milder strokes than people who had not taken aspirin, according to a report in the December issue of Stroke: Journal of the American Heart Association (2001-12-06)

Warfarin and aspirin provide no significant difference in preventing another stroke in the ischemic stroke patients
A study led by Columbia Presbyterian Medical Center researchers found that there is no significant different between the two drugs warfarin and aspirin in their ability to prevent recurrent strokes in patients who have had an ischemic stroke but who did not have atrial fibrillation. (2001-11-15)

Study shows that aspirin and warfarin are equally effective for stroke prevention
A study appearing in the November 15, 2001, issue of The New England Journal of Medicine* shows that aspirin works as well as warfarin in helping to prevent recurrent strokes in most patients. The Warfarin versus Aspirin Recurrent Stroke Study (WARSS) was a 7-year double-blind, randomized clinical trial involving 2,206 patients at 48 participating centers ¾ the largest trial to date comparing aspirin to warfarin for recurrent stroke prevention. (2001-11-14)

Stockings, heparin found to eliminate 'coach class' syndrome
In healthy individuals, (2001-11-13)

Development of blood clots following long-haul flights prevented with single dose of enoxaparin sodium
Deep-vein thrombosis (DVT) and pulmonary embolism, the potentially life-threatening disorders in which blood clots form primarily in the legs, were prevented in long-haul airline travelers with a history of heart disease through a single dose of the widely prescribed antithrombotic agent enoxaparin sodium (Clexane(R)/Lovenox(R)), according to a new study. The San Valentino Screening Project (the Italian equivalent of the well-known Framingham Heart Study) organised the study known as LONFLIT III. (2001-11-13)

LIFE-SAVER: World's largest cholesterol-lowering trial reveals massive benefits for high-risk patients
Around a third of all heart attacks and strokes can be avoided in people at risk of vascular disease by using statin drugs to lower blood cholesterol levels - irrespective of the person's age or sex, and even if their cholesterol levels do not seem high. That's the conclusion of UK researchers who have just completed the world's largest randomised trial on cholesterol-lowering therapy. (2001-11-13)

AIM Tip Sheet, November 6, 2001
1). Aspirin Not a Substitute for Colorectal Cancer Screening 2).Hepatitis B Virus (HBV) Studies Provide New Information 3). Gene Variations May Slow Progression from HIV Infection to AIDS (2001-11-05)

Aspirin not a cost effective substitute for colorectal cancer screening
Some animal studies have shown that aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) have an anti-tumor effect in the colon. Also, some studies in people suggest that these drugs may decrease the risk of colorectal cancer. (2001-11-05)

Aspirin not a substitute for colorectal cancer screening
Aspirin is not a cost-effective preventive measure or substitute for colorectal cancer screening tests, a new study finds. Some studies have suggested that aspirin and other non-steroidal anti-inflammatory drugs might reduce risk for colorectal cancer. The study is published in the November 6, 2001, issue of Annals of Internal Medicine. (2001-11-05)

Vitamin E and aspirin delay heart disease in mice even with high cholesterol levels
Vitamin E and a cox inhibitor such as aspirin lower the production of plaque in the blood vessels of mice by more than 80 percent, even when their cholesterol levels remain high, according to research findings from the University of Pennsylvania School of Medicine. (2001-10-18)

Antidepressants lower heart attack risk: selective serotonin reuptake inhibitors lessen chances of heart attacks in smokers
Drugs designed to fight depression may also prevent heart attacks, according to researchers at the University of Pennsylvania Medical Center. In a large study of smokers, the researchers associated a class of antidepressants, called selective serotonin reuptake inhibitors (SSRIs), with a lower heart attack risk. Their findings are published in the latest issue of Circulation: Journal of the American Heart Association. (2001-10-17)

Study: The rate of clots forming inside stents is three times higher than generally appreciated
A new analysis conducted by Duke University Medical Center cardiologists concludes that the incidence of potentially life-threatening clots forming inside stents -- tiny mesh girders designed to prop open newly cleared arteries -- is almost three times higher than previously reported. (2001-09-03)

New combination therapy could reduce Ischaemia after heart attack
Encouraging results from a fast-track study published in this week's issue of THE LANCET suggest a new therapeutic strategy for reducing ischaemic complications (coronary artery blockage) after heart attack. (2001-08-23)

Celebrex under study for lung cancer prevention
UCLA's Jonsson Cancer Center is seeking volunteers for two new research studies to determine if Celebrex, a common anti-inflammatory drug, can help prevent lung cancer. For the first time, the studies will investigate whether the drug can prevent lung cancer in people at high risk of developing the disease. (2001-08-02)

Highlights from Circulation: Journal of American Heart Association, June 19, 2001
Low molecular weight formulations of the anticoagulant drug heparin have ushered in a new era for treating blood clots that may allow heart patients to go home sooner. This development is reflected in (2001-06-18)

Blood clots are found in retinas of patients with diabetic retinopathy
Diabetic patients show a four-fold increase of blood clots in retinal capillaries than nondiabetic patients. Thus, diabetic patients may benefit from aspirin therapy to reduce their risk of developing diabetic retinopathy - the damage to tiny blood vessels in the back of the eye that causes many diabetic patients to go blind, according to a new study at The Schepens Eye Research Institute. (2001-06-11)

Aspirin targets key cell that triggers organ rejection and other immune responses, report University of Pittsburgh researchers in journal article
University of Pittsburgh researchers have identified a new cellular target for aspirin, shedding light on the mechanisms of the most widely used drug in the world and raising a set of intriguing questions, including whether aspirin could be useful for preventing organ rejection. (2001-06-04)

Scientists analyze stroke studies from the past 50 years; Success rate of experimental drugs described as 'remarkably dismal'
After analyzing trends in acute ischemic stroke studies from the past 50 years, scientists from UCLA and the University of Pennsylvania found a (2001-05-30)

PAR-2 and protective gastric secretion
Kawabata and colleagues have shown previously that the protease-activated receptor PAR-2 can activate secretion. This receptor, which may be best known for its ability to induce smooth muscle relaxation in the vasculature and bronchioles, is unusual in that it carries its own ligand as part of its sequence. Here, Kawabata et al. show that the corresponding peptide can stimulate sensory nerves in the stomach and activate the protective secretion of gastric mucus. (2001-05-29)

Older women less likely than men to get warfarin for irregular heartbeat
Elderly women - those older than 75 - were half as likely as elderly men to receive the drug warfarin, which treats irregular heartbeats that can increase stroke risk, researchers report in today's Circulation: Journal of the American Heart Association. (2001-05-13)

Quality improvement project boosts hospital care for older heart patients
Hospitals can significantly improve the care of people 65 years old and older who are admitted for acute heart attack by adopting specific treatment guidelines shown by research to be highly effective. (2001-04-26)

Diabetes doubles heart disease death risk; diabetes control approach may effect outcomes
After an analysis of data collected from two large multi- center clinical trials, Duke University Medical Center researchers have found that patients with diabetes have an almost two-fold increase in dying or suffering severe outcomes from heart disease compared to non-diabetics. (2001-03-20)

MGH researchers shed new light on how pain killers work
Researchers at Massachusetts General Hospital have shown for the first time how a class of common pain-relieving agents called nonsteroidal anti-inflammatory drugs (NSAIDs) - better known as aspirin and aspirin-like products - work by acting within the central nervous system as well as in the inflamed region around the source of pain. (2001-03-20)

Regional variations in the use of heart drugs
While the use of different therapies to treat or prevent heart attacks varies widely across the United States and Canada, Duke researchers found that regions with the highest use of percutaneous coronary interventions had the lowest rates of evidence-based medications. (2001-03-19)

While noting improvements, two Duke studies find doctors still not using drugs shown to be beneficial in clinical trials
Two different analyses by Duke University Medical Center cardiologists have shown that while multi-center clinical trials involving thousands of patients have clearly demonstrated that certain drugs can improve the outcomes for heart patients and save lives, the message is not being uniformly heard by physicians. (2001-03-19)

U-M patients take their medicine
For patients with heart conditions, medication can mean the difference between running a mile and racing to the emergency room. Few data exist to show whether these patients take their meds. U-M completed the first-of-its-kind study to see how their patients did. (2001-03-19)

Wide variability in use of proven medicine: Those who would benefit most less likely to receive latest therapies
After analyzing one of the most comprehensive and representative registries of heart patients in the world, Duke University researchers found that of five therapies proven effective by clinical trials, the usage ranged from 57 percent for ACE inhibitors to 93 percent for aspirin. (2001-03-18)

New program shown to help heart attack patients get the best care
Ten Detroit-area hospitals are taking better care than ever of their heart attack patients, thanks to a simple tool kit that helps physicians, nurses and patients remember to take advantage of all the proven therapies that national guidelines recommend. The program could be a model for hospitals nationwide. (2001-03-18)

Aspirin and other non-specific COX inhibitors may slow atherosclerosis
Mouse-model research by scientists at the University of Pennsylvania School of Medicine has demonstrated that aspirin, ibuprofen and other drugs in the class of pharmaceuticals known as non-specific COX inhibitors may aid substantially in preventing heart disease, slowing the build- up of plaque in blood vessels by more than 50 percent. (2001-03-06)

A paradox helps explain how aspirin works
Even though aspirin's pain-killing capacity was well known to Hippocrates in the fifth century B.C., exactly what it does remains somewhat of a mystery. Now, Johns Hopkins researchers have shown that aspirin inhibits interleukin-4, a protein involved in allergic reactions and inflammation. (2001-03-04)

New treatment for whiplash induced headaches
Doctor's at the University of Pennsylvania's Department of Rehabilitation Medicine have demonstrated a new and successful technique for treating headaches stemming from whiplash injuires by injecting a steroid into the C2-3 joint where the skull connects to the spine. (2001-02-28)

Anti-clotting drug safer than aspirin at averting second strokes
An anti-clotting drug is as effective as aspirin at preventing a second stroke, but without the bleeding complication sometimes associated with aspirin use, according to two new studies. The studies were reported today at the American Stroke Association's 26th International Stroke Conference. The American Stroke Association is a division of the American Heart Association. (2001-02-14)

Low dose aspirin may help to prevent pre-eclampsia during pregnancy
A study in this week's BMJ shows that antiplatelet drugs, largely low dose aspirin, have small to moderate benefits when used for prevention of pre-eclampsia and its complications during pregnancy. (2001-02-08)

Untangling prostaglandin signaling
Prostaglanin E2 (PGE2)signaling contributes to each of the manifestations that classically define inflammation--redness, heat and pain. Although non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin are well kown to inhibit this pathway by blocking prostaglandin biosynthesis, more specific agents would be useful, given the disparate biological responses that prostaglanins mediate. (2001-01-30)

Eating more fish and n3 fatty acids associated with reduced risk of stroke for women
Higher consumption of fish and n3 polyunsaturated fatty acids is associated with a reduced risk of some types of stroke among middle-aged women, and primarily among women who do not take aspirin regularly, according to an article in the January 17 issue of The Journal of the American Medical Association (JAMA). (2001-01-15)

Aspirin use may increase pancreatic cancer risk
The many health benefits of regular aspirin use have been well-documented, and include the prevention of certain cancers, heart attacks and strokes, as well as dementia, Alzheimer's disease and cataracts. But a new study advises women that aspirin may not always be helpful. According to research presented today at the American Association for Cancer Research Second Annual International Conference on Frontiers in Cancer Prevention Research, extended regular use of aspirin may be associated with a significantly increased risk of pancreatic cancer among women. (2000-12-31)

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