Current Biomaterials News and Events | Page 3

Current Biomaterials News and Events, Biomaterials News Articles.
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Novel anti-cancer nanomedicine for efficient chemotherapy
Researchers have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for efficient cancer chemotherapy. (2019-09-17)

Bioengineers explore cardiac tissue remodeling after aortic valve replacement procedures
Researchers have developed biomaterial-based 'mimics' of heart tissues to measure patients' responses to an aortic valve replacement procedure, offering new insight into the ways that cardiac tissue re-shapes itself post-surgery. (2019-09-11)

New hydrogels show promise in treating bone defects
Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration. Once injected in a mouse model, the new hydrogel is shown to induce migration of naturally occurring stem cells to better promote bone healing. Current experimental applications using hydrogels and stem cells introduced into the body or expensive biological agents can come with negative side effects. (2019-08-20)

FRESH 3D printing used to rebuild functional components of human heart
Scientists are a major step closer to 3D bioprintng functional organs, after team of Carnegie Mellon University researchers devise a method of rebuilding components of the human heart, according to a study published in Science. The team developed an advanced version of Freeform Reversible Embedding of Suspended Hydrogels (FRESH) technology, licensed to FluidForm, to 3D print collagen with unprecedented complexity and construct components of the heart, from small blood vessels to valves to beating ventricles. (2019-08-01)

3D printing new parts for our broken hearts
Researchers have developed a 'FRESH' new method of 3D printing complex anatomical structures out of collagen -- a primary building block in many human tissues. (2019-08-01)

New technique could help engineer polluted water filter, human tissues
Scientists can turn proteins into never-ending patterns that look like flowers, trees or snowflakes, a technique that could help engineer a filter for tainted water and human tissues. Their study, led by researchers at Rutgers University-New Brunswick, appears in the journal Nature Chemistry. (2019-07-24)

Researchers: Eggshells can help grow, heal bones
Eggshells can enhance the growth of new, strong bones needed in medical procedures, a team of UMass Lowell researchers has discovered. (2019-07-08)

Helping the body's ability to grow bone
For the first time, scientists have been able to study how well synthetic bone grafts stand up to the rigors and 'strains' of life, and how quickly they help bone re-grow and repair. (2019-06-24)

'Green Revolution' in RNAi tools and therapeutics
A team from Nanjing University in China reported that the small silencing RNA sequences against HBsAg generated in edible lettuce (Lactuca sativa L.) can specifically bind and inhibit gene expression in p21-HBsAg knock-in transgenic mice and improve liver injury at a relatively low level when compared to synthetic siRNAs. This work may also be helpful to the treatment of hepatitis C and other infectious diseases and bring a 'green revolution' in RNAI tools and therapeutics. (2019-06-10)

First-ever spider glue genes sequenced, paving way to next biomaterials breakthrough
UMBC's Sarah Stellwagen and Rebecca Renberg at the Army Reserach Lab have determined the first-ever complete sequences of two spider glue genes. Spider glue is a modified form of spider silk that keeps a spider's prey stuck in its web, and it could have applications in organic pest control and beyond. The sequences took two years to determine and required 'third-generation' sequencing techniques because of the length and repetitive nature of the genes. (2019-06-05)

Molecular bait can help hydrogels heal wounds
Rice University bioengineers develop modular, injectable hydrogels enhanced by bioactive molecules anchored in the chemical crosslinkers that give the gels structure. The hydrogels can be mixed at room temperature and customized to help heal a variety of wounds. (2019-06-05)

Cell membrane as coating materials to better surface engineering of nanocarriers
Coating natural cell membranes on synthetic nanocarriers represents an innovative strategy of surface engineering. Cell membranes-coatings offer nanocarriers with proteins, antigens, lipids, and immunological moieties. Nanocarriers are turned into cell-like nanoparticles and hold immunosuppressive capability, long circulation time, and targeted recognition, presenting a good performance in vivo. Here, cell membrane-covered nanocarriers as biomaterials will be reviewed from design to assembly as well as relevant promising biomedical applications. (2019-05-14)

Food dye, the secret ingredient for 3D printing biocompatible hydrogels with life-like vasculature
Yellow food dye #5 -- a common food additive -- is revealed as the secret ingredient in 3D printing biomaterials with complex physically entangled networks, which characterize biological tissues, according to a new report. (2019-05-02)

Welding with stem cells for next-generation surgical glues
Scientists at the University of Bristol have invented a new technology that could lead to the development of a new generation of smart surgical glues and dressings for chronic wounds. The new method, pioneered by Dr. Adam Perriman and colleagues, involves re-engineering the membranes of stem cells to effectively 'weld' the cells together. (2019-04-23)

Biomedical engineers grow cardiac patches to help people recover from heart attacks
A little goes a long way. Tiny blood vessels are essential for regenerative engineering and a team led by engineers from Michigan Tech has detailed innovative methods to ensure highly aligned, dense and mature microvasculature in engineered tissue that can be used for cardiac patches. (2019-03-28)

3D printed tissues may keep athletes in action
Bioscientists at Rice and the University of Maryland with the Center for Engineering Complex Tissues learn to 3D-print scaffolds that may help heal osteochondral injuries of the sort suffered by many athletes. (2019-03-28)

A new technology developed to detect and analyze colorless and transparent biomaterials
DGIST Professor Jae Eun Jang's team, plasmonic nano structure developed a technology that generates colorless and transparent biomaterials. Will contribute to biomaterial detection for brain disease research & treatment. (2019-03-05)

Dental fillings could last twice as long
A compound used to make car bumpers strong and protect wood decks could prevent return visits to the dentist's office. A team of researchers with the OHSU School of Dentistry in Portland, Oregon, have created a filling material that's two times more resistant to breakage than standard fillings. The team also has developed an adhesive that's 30 percent stronger after six months in use than adhesives that are currently used to keep fillings in place. (2019-03-04)

Scientists at FAU are researching a new method for developing artificial ovaries
An interdisciplinary team of researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg led by Professor Aldo R. Boccaccini from the Chair of Materials Science (biomaterials) and Professor Dr. Ralf Dittrich from the Department of Obstetrics and Gynaecology at Universitätsklinikum Erlangen have taken an important step towards developing artificial ovaries for patients suffering from cancer. (2019-02-28)

Blood runs deep: Lab blood vessel model sheds light on angiogenesis
Researchers at the University of Tokyo and at CNRS in France revealed the importance of the molecule EGFL7 for angiogenesis and endothelial integrity using an artificially created blood vessel model called a microvessel-on-a-chip. They showed that EGFL7 knockdown in the endothelial cells forming this model resulted in reduced angiogenesis and impaired barrier function. This work suggested the value of targeting EGFL7 and of using the microvessel-on-a-chip in the pursuit of treatments for diseases like cancer and diabetic retinopathy. (2019-01-31)

RCSI researchers develop new treatment for bone infection using copper-rich glass implant
A team of researchers led by RCSI (Royal College of Surgeons in Ireland), have developed a new treatment for the particularly difficult-to-treat bone infection, osteomyelitis. (2019-01-30)

Bioengineering & Translational Medicine honors biotech pioneers Langer and Peppas
Bioengineering & Translational Medicine (BioTM), published by Wiley on behalf of the American Institute of Chemical Engineers (AIChE) and its Society for Biological Engineering (SBE), has released a tribute issue dedicated to research inspired by Robert Langer and Nicholas Peppas -- two biotechnology luminaries whose game-changing contributions to drug delivery and biomaterials have made those fields integral elements of modern chemical engineering research and education. (2019-01-18)

Scientists generate high-quality human vascular cells through genome editing technology
Scientists from the Institute of Biophysics of the Chinese Academy of Sciences (CAS), Peking University and the Institute of Zoology of CAS have generated the world's first genetically enhanced human vascular cells by targeting a single longevity gene, FOXO3. The findings prove the feasibility of using gene-editing strategies to obtain high-quality, safe human vascular cell grafts and make it possible to scale up and standardize the generation of such cells for therapeutic use. (2019-01-17)

Reviewing advanced applications in drug delivery and medicine
This review seeks to analyze current advances of potential applications of graphene and its family of nano-materials for drug delivery and other major biomedical purposes. (2019-01-11)

The potential of nanomaterials to activate the body's antitumor immune response investigated
Immunity plays an immense role in the body's fight against cancer. Every day, the cells of the immune system check all the cells of our body for 'normalcy' and kill the degenerated cells. Sometimes cells hide from the immune system and escape the immunological control, and then a tumor develops. Today, there are many different ways to deal with tumors, but often they prove incurable. (2018-12-19)

Pitt engineer-clinician team uses 'active wrinkles' to keep synthetic grafts clean
To improve the success rate of synthetic grafts, a research team led by the University of Pittsburgh are investigating whether the 'active wrinkles' on the interior surface of arteries may help improve synthetic graft design and create a better alternative to autologous grafts for bypass surgery. (2018-11-27)

New device could monitor anticoagulant treatments with to deliver personalized therapies
Researchers of the Consejo Superior de Investigaciones Científicas (CSIC), the Catalan Institute of Nanoscience and Nanotechnology (ICN2) and CIBER Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) have developed a biosensor device which allows the monitoring of anticoagulants such as Sintrom® (acenocoumarol) to deliver a personalized therapy in which the patient or doctor can adjust the drug dose to achieve the optimal effect. (2018-11-26)

Citrate-based biomaterial fuels bone healing with less rejection
A material based on a natural product of bones and citrus fruit, called citrate, provides the extra energy that stem cells need to form new bone tissue, according to a team of Penn State bioengineers. Their new understanding of the mechanism that allows citrate to aid in bone regeneration will help the researchers develop slow-release, biodegradable, citrate-releasing scaffolds to act as bone-growth templates to speed up healing in the body. (2018-11-26)

Scientists developed enzymes with remote control
Scientists developed a method to enhance the activity of enzymes by using radio frequency radiation. The method requires making a special complex consisting of enzymes and magnetic nanoparticles. The particles can adsorb radio emission and convert it to heat, resulting in enzymatic processes acceleration by more than four times. Such method can be used to create radio-controlled biochemical systems and adjust metabolism in living organisms. The results are published in ACS Biomaterials Science & Engineering. (2018-11-21)

Nanotubes built from protein crystals: Breakthrough in biomolecular engineering
Researchers at Tokyo Tech have succeeded in constructing protein nanotubes from tiny scaffolds made by cross-linking of engineered protein crystals. The achievement could accelerate the development of artificial enzymes, nano-sized carriers and delivery systems for a host of biomedical and biotechnological applications. (2018-11-14)

Patients' own cells and materials used to create personalized tissue implants of any kind
In a new study, Tel Aviv University researchers reveal how they invented the first fully personalized tissue implant, engineered from a patient's own materials and cells. As a result, the risk of an immune response to an organ implant virtually disappears, the researchers say. (2018-11-12)

Scientists grow functioning human neural networks in 3D from stem cells
A team of researchers has developed three-dimensional (3D) human tissue culture models for the central nervous system that mimic structural and functional features of the brain and demonstrate neural activity sustained over a period of many months. With the ability to populate a 3D matrix of silk protein and collagen with cells from patients with Alzheimer's disease, Parkinson's disease, and other conditions, the tissue models allow for the exploration of cell interactions, disease and response to treatment (2018-10-18)

Biomaterials with 'Frankenstein proteins' help heal tissue
Biomedical engineers from Duke University and Washington University in St. Louis have demonstrated that, by injecting an elastic biomaterial made from ordered and disordered proteins, a scaffold can form that responds to temperature and easily integrates into tissue. (2018-10-15)

Switching DNA and RNA on and off
DNA and RNA are naturally polarised molecules. Scientists believe that these molecules have an in-built polarity that can be reoriented or reversed fully or in part under an electric field. In a new study published in EPJ E, See-Chuan Yam from the University of Malaya, Kuala Lumpur, Malaysia, and colleagues show that all the DNA and RNA building blocks, or nucleobases, exhibit a non-zero polarisation in the presence of polar atoms or molecules such as amidogen and carbonyl. (2018-08-21)

UCLA bioengineers use magnetic force to manage pain
UCLA bioengineers have demonstrated that a gel-like material containing tiny magnetic particles could be used to manage chronic pain from disease or injury. Broadly, the study demonstrates the promising use of biomechanical forces that push and pull on cells to treat disease. (2018-08-07)

Alzheimer's in mini format: A novel tool to study disease mechanisms and possible remedies
DZNE scientists have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue. This experimental tool can be used to study mechanisms of pathology and help to find new therapeutic approaches, the researchers say. Their results, published in Developmental Cell, indicate that modulating the immune system can trigger neuronal repair processes and thus possibly help the brain to better cope with Alzheimer's. (2018-07-02)

Plaster which sticks inside the mouth will revolutionise treatment of oral conditions
A new biodegradable patch administers steroids directly to oral ulcers and forms a protective barrier. (2018-06-25)

Flexible solar cells: Will they someday power your devices?
Researchers in Finland and Montreal are looking at the challenges of mass producing and commercializing the now-experimental technology. (2018-06-06)

Origami inspires new tech for tissue regeneration
Origami -- the Japanese art of folding paper into shapes and figures -- dates back to the sixth century. At UMass Lowell, it is inspiring researchers as they develop a 21st century solution to the shortage of tissue and organ donors. (2018-05-24)

Scientists in Russia and Singapore investigate inorganic biomaterials with antimicrobial properties
A team of scientists from the Lobachevsky University Department of Solid State Chemistry under Dr. Evgeny Bulanov has developed a new method for obtaining bismuth-containing apatite and has studied its crystal structure and thermodynamic properties with the purpose of modeling the behavior of this material under service conditions. (2018-05-14)

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