Current Biopsy News and Events

Current Biopsy News and Events, Biopsy News Articles.
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Child brain tumors can be classified by advanced imaging and AI
Diffusion weighted imaging and machine learning can successfully classify the diagnosis and characteristics of common types of paediatric brain tumours a UK-based multi-centre study, including WMG at the University of Warwick has found. This means that the tumour can be characterised and treated more efficiently. (2021-02-15)

Liquid biopsy for colorectal cancer could guide therapy for tumors
A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor. Such a biopsy can detect lingering disease and could serve as a guide for deciding whether a patient should undergo further treatments due to some tumor cells evading an initial attempt to eradicate the cancer. (2021-02-12)

Study: New prostate cancer test could avoid unnecessary biopsies
A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. (2021-02-11)

HKBU and CUHK launch Spermine Risk Score for prostate cancer diagnosis
Researchers from Hong Kong Baptist University (HKBU) and the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have jointly developed the Spermine Risk Score which, coupled with the use of a urine test, provides a non-invasive and more reliable method for the diagnosis of prostate cancer. In a study conducted by the researchers, about 37% of the patients, who were ultimately found to have no prostate cancer, can avoid undergoing a prostate biopsy procedure. (2021-02-08)

Clinical trial: Using MRI for prostate cancer diagnosis equals or beats current standard
The results of a Phase III randomized clinical trial have shown that when it comes to detecting clinically significant prostate cancer, Magnetic Resonance Imaging (MRI) with targeted biopsies (MRI-TBx) matches the current standard and brings a multitude of advantages. The PRostate Evaluation for Clinically Important Disease: MRI vs Standard Evaluation Procedures (PRECISE) study will help to make prostate cancer diagnosis more accurate and less invasive. (2021-02-04)

Study examines role of biomarkers to evaluate kidney injury in cancer patients
A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells. (2021-02-03)

CT identifies patients with high-risk nonalcoholic fatty liver disease (NAFLD)
According to ARRS' American Journal of Roentgenology, Fibrosis-4 and multiple CT findings can identify patients with high-risk nonalcoholic fatty liver disease--advanced fibrosis or cirrhosis, that is--though the presence of nonalcoholic steatohepatitis remains elusive on CT. (2021-01-22)

Cancer can be precisely diagnosed using a urine test with artificial intelligence
The Korea Institute of Science and Technology(KIST) announced that the collaborative research team led by Dr. Kwan Hyi Lee from the Biomaterials Research Center and Professor In Gab Jeong from Asan Medical Center developed a technique for diagnosing prostate cancer from urine within only twenty minutes with almost 100% accuracy. The research team developed this technique by introducing a smart AI analysis method to an electrical-signal-based ultrasensitive biosensor. (2021-01-21)

Raman spectroscopy shows promise for diagnosing oral cancer
In a new study, researchers show that a light-based analytical technique known as Raman spectroscopy could aid in early detection of oral squamous cell carcinoma (OSCC). (2021-01-13)

An epidemic of overdiagnosis: Melanoma diagnoses sky rocket
In a Sounding Board article, Welch and colleagues present evidence for why they believe that increased diagnostic scrutiny is the primary driver of the rapid rise in melanoma diagnoses. (2021-01-06)

Too many donor kidneys are discarded in U.S. before transplantation
a large portion of the discarded kidneys would function acceptably if transplanted, according to a new study from a team led by researchers in the Perelman School of Medicine at the University of Pennsylvania and the Paris Translational Research Center for Organ Transplantation. (2020-12-15)

Cervical cancer survival may improve by targeting senescent "zombie" cells
How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a ''zombie'' cell state called senescence, Medical College of Georgia scientists report. (2020-12-07)

Sensor can detect scarred or fatty liver tissue
MIT engineers have now developed a diagnostic tool, based on nuclear magnetic resonance (NMR), that could be used to detect both fatty liver disease and liver fibrosis. (2020-12-02)

Food, housing insecurities may delay breast cancer diagnosis
Women who experience food or housing insecurity may be at risk for undiagnosed breast cancer due to lapses in follow-up appointments, according to research being presented at the annual meeting of the Radiological Society of North America (RSNA). (2020-11-19)

Importance of mitochondrial-related genes in dilated cardiomyopathy
Importance of Mitochondrial-Related Genes in Dilated Cardiomyopathy Based on Bioinformatics Analysis. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0588, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Shantou, China consider the importance of mitochondrial-related genes in dilated cardiomyopathy. (2020-11-19)

'Vanished' or 'hidden' prostate cancer? Men with negative biopsies during active surveillance have good outcomes
Can early-stage prostate cancer ''vanish'' during follow-up? More likely the cancer is just ''hidden''--either way, negative biopsies during active surveillance for prostate cancer are associated with excellent long-term outcomes, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. (2020-11-17)

A new diagnostic method predicts which cancer patients will respond to immunothe
An international group led by Dr Banafshe Larijani, an Ikerbasque researcher seconded to the Biofisika Institute (UPV/EHU-University of the Basque Country, CSIC), has developed a new diagnostic method making it possible to accurately predict which cancer patients will respond positively to immunotherapy. This method will allow oncologists to tailor treatment to each patient and avoid therapies that are not going to be successful. (2020-11-16)

Ultrasound-guided percutaneous needle biopsy excellent for small pleural lesions diagnosis
According to an open-access article in ARRS' American Journal of Roentgenology, ultrasound (US)-guided percutaneous pleural needle biopsy (PCPNB) has excellent diagnostic accuracy for small pleural lesions. ''In multivariable analysis,'' the authors concluded, ''pleural morphology on US and needle pathway length through the pleura independently predicted diagnostic yield,'' adding that if the pleura is nodular or thicker than 4.5 mm on CT, US-guided PCPNB is justifiable as an initial or repeat diagnostic test. (2020-11-06)

Blood cell mutations confound prostate cancer liquid biopsy results
Unrelated mutations, when present in the blood, can give false positive results in men with advanced prostate cancer undergoing liquid biopsies. Such tests, which look for variants in cell-free DNA that tumors shed into the blood plasma, help determine suitable treatment options. Incorrect test results might mean the patient gets therapies unsuited for his cancer. A simple solution overcomes this problem. (2020-11-05)

Cerebrospinal fluid as liquid biopsy for characterizing & policing of medulloblastoma
Building on previous research led by Joan Seoane, Director of Translational Research at the Vall d'Hebron Institute of Oncology (VHIO) and ICREA Research Professor, latest findings from a proof-of-concept study published in Nature Communications, show that the analysis of cerebrospinal fluid (CSF) circulating tumor DNA (ctDNA), allows for the more precise characterization, molecular diagnosis (including subtyping and risk stratification), and real time tracking of medulloblastoma (MB) - the most prevalent malignant brain tumor in childhood. (2020-10-27)

18F-Fluciclovine PET/MRI for prostate cancer staging, androgen deprivation evaluation
According to an open-access article in ARRS' American Journal of Roentgenology, fluorine-18-labeled fluciclovine PET/MRI demonstrated utility in the initial staging of high-risk prostate cancer, as well as for evaluating the response to androgen deprivation therapy. Given the FDA approval and widespread availability of 18F-fluciclovine, the findings could have impact in the immediate future in guiding initial management of patients with prostate cancer. (2020-10-27)

City, University of London academics develop algorithm to analyse HeLa cancer cells
Dr Constantino Carlos Reyes-Aldasoro and Dr Cefa Karabag collaborate with the Francis Crick Institute on a novel approach published in the PLoS ONE journal, which significantly reduces the amount of time taken to analyse the cell line named after Henrietta Lacks, an African-American woman whose contribution to medical science was only formally acknowledged decades after her death. (2020-10-26)

Women with cervical cancer may have increased risk of injury during diagnostic workup
Among women participating in cervical cancer screening in Sweden, those with a diagnosis of invasive cervical cancer had an increased risk of iatrogenic injuries (as a consequence of medical intervention) and non-iatrogenic injuries (caused by accidents and self-harm) requiring hospitalization. (2020-10-21)

Highly effective tumor detection strategy for common childhood brain tumors
A team of scientists at Texas A&M University, Baylor College of Medicine and Texas Children's Hospital have developed a way to more accurately both detect and monitor a common type of pediatric brain cancer, setting the stage for giving clinicians a real-time view into how the cancer responds to treatment. (2020-10-21)

Breakthrough blood test developed for brain tumors
Genetic mutations that promote the growth of the most common type of adult brain tumors can be accurately detected and monitored in blood samples using an enhanced form of liquid biopsy developed by researchers at Massachusetts General Hospital (MGH). (2020-10-14)

Even mild fatty liver disease is linked to increased mortality
Non-alcoholic fatty liver disease, NAFLD, affects nearly one in four adults in Europe and the U.S. Earlier research has demonstrated an increased risk of death in patients with NAFLD and advanced fibrosis or cirrhosis. Now, researchers at Karolinska Institutet in Sweden and Massachusetts General Hospital in the U.S. show that mortality increases with disease severity, but even mild fatty liver disease is linked to higher mortality. The findings have been published in the journal Gut. (2020-10-12)

Researchers gain new insight on metastatic prostate cancer
An international research team has discovered a principle that explains the metastasising of prostate cancer. When cancer evolves within the prostate, multiple spatially intermixed cancer cell clones are created that may invade the organs surrounding the prostate. However, only one dominant cell clone spreads systemically in the body and creates metastases. In addition, new subcellular clones are often generated in metastases, which pass on to other metastases. (2020-10-08)

Hospitals serving minority patients follow breast cancer recommendations at similar rate
Among accredited U.S. cancer centers, hospitals serving primarily minority patients are as likely as other hospitals to offer the standard of surgical care for early-stage breast cancer. (2020-10-03)

Liquid biopsies timely and effective testing method for NSCLC patients in Canada
Next-generation sequencing (NGS) of cell-free DNA (cfDNA) obtained from blood samples may improve diagnostic testing in patients with advanced NSCLC, and may also be faster and less expensive compared to standard tissue profiling, according to research presented today at the IASLC 2020 Lung Cancer Hot Topic: Liquid Biopsy Virtual Conference. (2020-10-02)

Liquid biopsy faster than tissue biopsy, improves time to treat
A pilot study comparing the effects of a liquid biopsy with tissue-based test showed that liquid biopsy turn-around time for results was approximately 10 days faster than the tissue biopsy, according to research presented today at the IASLC 2020 Lung Cancer Hot Topic: Liquid Biopsy Virtual Conference. (2020-10-02)

Freezing prostate cancer: Study shows notable outcomes with cryoablation
A less-invasive treatment technique called hemi-gland cryoablation (HGCryo) -- destroying the areas of the prostate where cancers are located by freezing them -- provides a high rate of effective prostate cancer control, according to a new study published in The Journal of Urology®, Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. (2020-09-28)

Why some cancers may respond poorly to key drugs discovered
Scientists have identified a driver of drug resistance in breast, ovarian and prostate cancers that may help doctors predict which patients will become resistant to a class of drugs frequently used to treat BRCA 1/2-deficient tumors. (2020-09-22)

High-risk patients for colorectal cancer lack knowledge about colonoscopy
Many clinicians rely on self-reports from their high-risk patients about their need and proper interval for repeat surveillance colonoscopy. Researchers analyzed data on high-risk patients and found that 28 percent were unaware of either the need for a repeat colonoscopy or the proper surveillance interval. Of these, 16.6 percent were unaware of the proper three-year interval to obtain a follow-up surveillance colonoscopy. Also, 12 percent did not know that they required a follow-up surveillance colonoscopy. (2020-09-14)

Urine sediment test results, diagnoses vary significantly across nephrologists
A new study shows that nephrologists do not always agree on their interpretation of images from urine sediment tests, which are frequently ordered to evaluate a variety of kidney diseases. Led by researchers at Boston Medical Center and published in JAMA Network Open, the findings indicate the need to standardize education and training around evaluating urine sediment tests to improve the test's reliability, and help prevent misinterpretation and potential patient harm. (2020-08-21)

New 'nanopores' technique offers proof-of-concept of earlier, safer tumor detection
Liquid biopsies--identifying the presence of tumor DNA fragments or cells circulating in bodily fluids--have taken off in the last few years as a non-invasive and more accurate way to detect cancers. Unfortunately, the short-lived nature of these fragments remains a challenge for identifying mutations, particularly for early tumor detection. But a new technique incorporating nanopore technology could offer a powerful, fast and easy-to-use alternative. (2020-08-18)

Challenges in diagnosing hypersensitivity pneumonitis addressed in latest guidelines
More than 30 years after the last guidance on the clinical evaluation of hypersensitivity pneumonitis (HP), the American Thoracic Society - in collaboration with the Asociación Latinoamericana de Tórax or ALAT and the Japanese Respiratory Society- has developed new guidelines for clinicians. The guidelines are available online ahead of print in the American Journal of Respiratory and Critical Care Medicine. (2020-08-03)

Aerobic exercise could have the final say on fatty livers
Trinity College Dublin study is the first to demonstrate significant improvements in biopsy-measured liver outcomes in a metabolic associated fat liver disease (MAFLD) cohort following an exercise-only intervention, without clinically significant weight loss. (2020-07-29)

Mount Sinai researcher identifies single gene biomarker to differentiate between atopic dermatitis
Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology. (2020-07-21)

Prostate cancer: How can we decide when to treat?
You have been diagnosed with prostate cancer and your doctor gives you the option of not being treated, but of remaining under observation: is there any objective way you can decide to be treated or not treated? What should you do? Now using first results from analysis of the world's biggest Active Surveillance prostate cancer database, scientists have begun to identify which patients are at risk of the disease developing and which patients can continue to safely delay treatment. (2020-07-18)

Abnormal cells in early-stage embryos might not preclude IVF success
The presence of an abnormal number of chromosomes in the genetic profile of early-stage embryos may be far more common - and potentially less threatening - during normal human development than is currently appreciated, according to new research from Johns Hopkins University biologists. (2020-07-08)

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