Current Bleeding News and Events

Current Bleeding News and Events, Bleeding News Articles.
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New tech aims to tackle 'disseminated intravascular coagulation' blood disorder
Researchers have developed a new tool for addressing disseminated intravascular coagulation (DIC) - a blood disorder that proves fatal in many patients. The technology has not yet entered clinical trials, but in vivo studies using rat models and in vitro models using blood from DIC patients highlight the tech's potential. (2021-02-17)

Hydrogel promotes wound healing better than traditional bandages, gauzes
For explosion wounds as well as some incurred in disasters and accidents, severe hemorrhage is a leading cause of death. Hydrogel dressings, which have advanced in recent years, may help; they are good at promoting wound healing and can better meet the demands of different situations. Many are antibacterial, biodegradable, responsive, and injectable and can fill irregularly shaped wounds. In APL Bioengineering, researchers in China examine some of the recent advances. (2021-02-16)

Aspirin preferred to prevent blood clots in kids after heart surgery
Aspirin should be favoured over warfarin to prevent blood clotting in children who undergo a surgery that replumbs their hearts, according to a new study. (2021-02-14)

Preventive anti-clotting therapy does not boost survival of critically ill COVID patients
Although abnormal blood clotting has been identified as one of the primary causes of death from COVID-19, early treatment in an intensive care unit with therapeutic anticoagulation (anti-clotting) for adults who are critically ill with COVID-19 does not appear to improve chances of survival, and could do more harm than good by increasing the risk for major bleeding, a multicenter research group cautions. (2021-02-03)

Child head injury guidelines created
Australia's and New Zealand's first set of clinical guidelines for children's head injuries has been created. (2021-02-02)

International research network identifies triggers for severe course of liver cirrhosis
Acute-on-chronic liver failure (ACLF) is a common cause of death in patients with cirrhosis. In ACLF the progressive loss of function of the scarred liver can no longer be compensated (acute decompensation). As a result, other organs such as the kidney or brain fail. The triggers for acute decompensation of liver cirrhosis and an ACLF are most frequently bacterial infections, liver inflammation caused by alcohol, or a combination of both factors. (2021-02-02)

Bleeding gums may be a sign you need more vitamin C in your diet
Bleeding of the gums on gentle probing, or gingival bleeding tendency, and also bleeding in the eye, or retinal hemorrhaging, were associated with low vitamin C levels in the bloodstream. (2021-02-01)

Subset of COVID-19 patients have increased bleeding risk
A new potential biomarker raises concerns over the current standard for treating COVID-19 induced blood clots with high dose blood thinners. (2021-02-01)

90-day vaginal ring shows promise as method for preventing both HIV and pregnancy
A vaginal ring containing the antiretroviral drug dapivirine and the contraceptive hormone levonorgestrel delivered sustained levels of each drug when used continuously for 90 days - levels likely sufficient to serve its dual purpose for protecting against both HIV and unwanted pregnancy, according to results being presented at HIVR4P. The 90-day dual-purpose ring builds on the monthly dapivirine ring, which, if approved, would be the first biomedical HIV prevention method specifically for women. (2021-01-26)

Organizations collaborate to develop international von Willebrand Disease guidelines
The American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), National Hemophilia Foundation (NHF), and World Federation of Hemophilia (WFH) have developed joint clinical practice guidelines on the diagnosis and management of von Willebrand Disease (VWD), the world's most common inherited bleeding disorder. The guidelines were published today in Blood Advances. (2021-01-12)

Laypeople have difficulty estimating severity of blood loss
When an accident occurs, the reactions of bystanders are important. Researchers have studied whether laypeople realise the severity of the situation when someone in their proximity begins to bleed, and whether they can estimate how much the person is bleeding. The results show a discrepancy related to the victim's gender: for a woman losing blood, both blood loss and life-threatening injuries were underestimated. The study has been published in the scientific journal PLoS One. (2021-01-11)

Visible hydrogels for rapid hemorrhage control and monitoring
A collaborative team of clinical intervention radiology specialist and bioengineering researchers create a visual hydrogel for rapid hemorrhage control and monitoring by adding imaging particles made from tantalum hydrogel mixture. (2020-12-22)

New toolkit aims to improve quality of thrombosis data in COVID-19 trials
The ASH Research Collaborative (ASH RC) and the International Society of Haemostasis and Thrombosis (ISTH), two organizations with multidisciplinary expertise in blood clotting and bleeding disorders, have developed a toolkit to help clinical researchers from across medical disciplines design clinical trials that further the understanding of blood clotting events associated with COVID-19. (2020-12-17)

Surgical and drug treatment options lead to similar outcomes for diabetic eye disease
Surgical and injectable drug approaches are equally effective for treatment of bleeding inside the eye from proliferative diabetic retinopathy (PDR), according to a National Eye Institute (NEI)-supported clinical study from the DRCR Retina Network (DRCR.net). (2020-12-15)

Octapharma presents research on congenital & acquired bleeding disorders at ASH Meeting
Octapharma USA will present multiple clinical research posters focused on the efficacy and safety of fibryga®, Fibrinogen (Human) Lyophilized Powder for Reconstitution, for Intravenous Use in the treatment of congenital and acquired bleeding disorders during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, a virtual medical congress to be held December 5 - 8, 2020. (2020-12-03)

Octapharma USA presents bleeding disorders research at virtual ASH annual meeting
Octapharma USA will present its most recent rare bleeding disorders research initiatives during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, a virtual medical congress to be held December 5 - 8. (2020-12-01)

CHOP researchers reverse severe lymphatic disorder in patient with Noonan syndrome
Researchers at Children's Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, fluid collection around the lungs, and numerous surgeries that had been unable to resolve her symptoms. By identifying a genetic mutation along a pathway related to lymphatic vessel development and function, the research team was able to target the pathway using an existing drug they had used in a previous case to remodel a patient's lymphatic system. (2020-11-20)

One-month of dual anti-platelet therapy is safe and feasible after stent placement
A short, one-month treatment combining antiplatelet medication and aspirin followed by an aspirin-only regime was as effective as a 6- to 12-month course of dual treatment at preventing death, heart attacks, strokes, bleeding or the need for additional stent placement. The results of this study could lead to changes in treatment and improve patient compliance, lower costs and fewer side effects. (2020-11-16)

Children with asymptomatic brain bleeds as newborns show normal brain development at age 2
A study by UNC researchers finds that neurodevelopmental scores and gray matter volumes at age two years did not differ between children who had MRI-confirmed asymptomatic subdural hemorrhages when they were neonates, compared to children with no history of subdural hemorrhage. (2020-10-30)

Radical diagnostic could save millions of people at risk of dying from blood loss
Engineers at Monash University in Australia have developed a fast, portable and cheap diagnostic that can help deliver urgent treatment to people at risk of dying from rapid blood loss. This portable diagnostic measures fibrinogen concentration in blood. (2020-10-29)

Aspirin use best for those with high coronary calcium, low risk of bleeding
DALLAS - Oct. 28, 2020 - An X-ray test commonly used to assess hardening of the arteries could help doctors decide whether the benefits of taking aspirin to prevent a first heart attack or stroke outweigh the risks of bleeding from its use, UT Southwestern research suggests. (2020-10-29)

New therapeutic approach against leukemia
Using an RNA molecule complex, researchers can prevent retention of cancer stem cell in their tumor supporting niche (2020-10-23)

New study: aspirin use reduces risk of death in hospitalized patients
Hospitalized COVID-19 patients who were taking a daily low-dose aspirin to protect against cardiovascular disease had a significantly lower risk of complications and death compared to those who were not taking aspirin, according to a new study led by researchers at the University of Maryland School of Medicine (UMSOM). (2020-10-22)

Results from the cobra-reduce trial reported at TCT Connect
For patients undergoing percutaneous coronary intervention (PCI) that also require oral anticoagulation, treatment with a nanotechnology polymer-coated stent plus 14-day dual anti-platelet therapy (DAPT) did not reduce bleeding or establish non-inferior outcomes for thrombotic events compared with a drug-eluting stent (DES) and standard three or six-month DAPT therapy. (2020-10-17)

Results of an individual patient data pooled analysis reported at RCT Connect
An individual patient data pooled analysis comparing the use of bivalirudin versus heparin in heart attack patients undergoing percutaneous coronary intervention (PCI) found that bivalirudin use was associated with similar overall rates of 30-day mortality across all heart attack patients, but lower rates of serious bleeding events. Moreover, mortality was reduced in patients with ST-segment elevation myocardial infarction (STEMI) who were treated with a post-PCI bivalirudin infusion. (2020-10-14)

'Less pain' to remove tonsils
A 10-year study from Flinders University has found ''shrinking'' tonsils results in far less pain and bleeding than a full tonsillectomy. The research paper, published this month in the Australian and New Zealand Journal of Surgery, looked at 608 children who underwent tonsil surgery between 2008 and 2018. (2020-10-13)

STOP THE BLEED training has saved lives from Sierra Leone to Connecticut
Two studies presented at the American College of Surgeons (ACS) Clinical Congress 2020 provide evidence that STOP THE BLEED® training is effective and has made a lifesaving difference around the world. (2020-10-03)

Researchers zero in on genetic connection to postpartum hemorrhage
Researchers have identified genetic mutations that appear to protect women from severe bleeding after childbirth, a leading cause of maternal death. A preliminary study of the findings is being presented at the ANESTHESIOLOGY® 2020 annual meeting. (2020-10-03)

New way of giving life-saving drug will help frontline responders save the lives of trauma victims
A life-saving treatment for bleeding trauma victims, tranexamic acid (TXA), can now be given by a simple injection at the scene of the injury, according to a new study in British Journal of Anaesthesia. (2020-09-30)

Smoking linked to bleeding in the brain in large, long-term study of twins
Researchers in Finland found a link between smoking and subarachnoid hemorrhage (SAH), a type of bleeding stroke, in a study of more than 16,000 pairs of twins over 42 years. The study found that bleeding in the brain can be explained to a greater degree by environmental risk factors, such as smoking, than by genetic influence. (2020-09-17)

Study reveals best anti-clotting strategy after heart valve intervention
The POPular TAVI trial has challenged current guideline recommendations on antiplatelet treatment after transcatheter aortic valve implantation (TAVI) in patients not taking oral anticoagulation. The findings are presented in a Hot Line session today at ESC Congress 2020. (2020-08-31)

Age-appropriate contraception counseling helps health care providers educate teens
Preventing unplanned pregnancies in adolescents with effective and easy-to-use contraception is key to ensuring that adolescents do not become parents before they are ready. Adolescents view their health care providers as trusted sources of medical information. Thus, providers are tasked with providing adolescent patients with comprehensive, age-appropriate and nonjudgmental contraception counseling. (2020-08-27)

Survey finds most Americans feel unprepared to aid victims after a mass casualty attack
A new national survey by Orlando Health finds the majority of Americans are not confident that they could provide life-saving aid following a violent mass attack. The survey found that although most Americans feel they could call 911 and about half could provide information to first responders, confidence drops when it comes to administering first aid (42%) or applying a tourniquet (41%). (2020-08-24)

Study identifies optimal timing for phone calls after skin surgery
A new study from the University of Missouri School of Medicine provides insight into how the timing of post-operative phone calls can address pain, bleeding and overall patient satisfaction after Mohs micrographic surgery. (2020-08-18)

Blood-thinner with no bleeding side-effects is here
In a study led by EPFL, scientists have developed a synthetic blood-thinner that, unlike all others, doesn't cause bleeding side-effects. The highly potent, highly selective, and highly stable molecule can suppress thrombosis while letting blood clot normally following injury. (2020-08-04)

Portable, injectable clotting agent could treat trauma victims on the front lines
In a hospital, internal bleeding can be controlled with the transfusion of clotting agents, such as platelets, but they require careful storage and refrigeration and can't be carried by first responders. Now, researchers report an injectable clotting agent that reduced blood loss by 97 percent in mice models. The freeze-dried agent, which has a physical consistency of cotton candy, can be stored at room temperature for several months and reconstituted in saline before injection. (2020-07-31)

NSAIDs increase cardiovascular, bleeding risk in Korean heart attack patients
Use of NSAIDs to treat first-time heart attack patients significantly increased the risk for cardiovascular and bleeding events post-heart attack in a nationwide Korean study, published today in the Journal of the American College of Cardiology. (2020-07-27)

IUDs successfully manage menstrual pain in adolescents with disabilities
Adolescents and young women with disabilities can stop periods and get relief from distressing menstrual symptoms with IUDs, in the largest study in this population to date. (2020-07-23)

Post-surgical bleeding associated with more deaths when compared to blood clots after surgery
Post-surgical bleeding is associated with more deaths than blood clots from surgery, according to a Vanderbilt University Medical Center study published in the journal Anesthesia & Analgesia. (2020-07-21)

New antiplatelet drug shows promise for treating heart attack
Researchers have developed a new drug that prevents blood clots without causing an increased risk of bleeding, a common side effect of all antiplatelet medications currently available. A new study describes the drug and its delivery mechanisms and shows that the drug is also an effective treatment for heart attack in animal models. (2020-07-15)

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