Current Blindness News and Events

Current Blindness News and Events, Blindness News Articles.
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Improved vectors for ocular gene therapy
Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development. Novel gene vectors now achieve widespread gene delivery and reduce the risks associated with these approaches. (2021-02-22)

New therapeutic approach may help treat age-related macular degeneration effectively
Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy. Now, scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide. Their results are reported in The American Journal of Pathology, published by Elsevier. (2021-02-22)

New research sheds light on vision loss in Batten disease
Progressive vision loss, and eventually blindness, are the hallmarks of juvenile neuronal ceroid lipofuscinosis (JNCL) or CLN3-Batten disease. New research shows how the mutation associated with the disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss. (2021-02-05)

Synthesized very-long-chain polyunsaturated fatty acids improved retinal function in mice
A University of Utah ophthalmologist is investigating how lipids known as VLC-PUFAs could be used to prevent eye disease thanks to a new way to synthesize them for research. (2021-02-04)

Halved risk for severe retinal disease in extremely premature infants
Risk for a severe form of retinopathy of prematurity, which can cause blindness in extremely premature babies, was halved when the newborns were given a new supplement combining various fatty acids. This was shown in a Swedish study led from the University of Gothenburg. (2021-02-01)

Retinal cell transplant clears experimental hurdle toward treating blindness
Retinal cells derived from adult human eye stem cells survived when transplanted into the eyes of monkeys, an important early step in the validation of this approach for treating blindness, according to a study by Liu, et al recently published in Stem Cell Reports. The retinal pigment epithelium (RPE), a layer of pigmented cells in the retina, is essential for sustaining normal vision. Blindness due to RPE dysfunction, such as macular degeneration, affects about 200 million people worldwide. (2021-01-14)

Scientists take important step toward using retinal cell transplants to treat blindness
Latest discovery is promising step in use of cell therapy to treat retinal diseases (2021-01-14)

AI algorithms detect diabetic eye disease inconsistently
In a paper published Jan. 5 in Diabetes Care, researchers compared seven algorithms to detect diabetic retinopathy against the diagnostic expertise of retina specialists. (2021-01-05)

New research shows masks change the way we process faces
New study finds that our ability to recognize faces is severely impaired by masks, and this decreased face perception is impacting our social interactions with others. (2020-12-21)

AI-supported test predicts eye disease three years before symptoms
A pioneering new eye test, developed by scientists at UCL in collaboration with the Western Eye Hospital, London, may predict wet AMD, a leading cause of severe sight loss, three years before symptoms develop, finds a new study in Expert Review of Molecular Diagnostics. (2020-12-18)

Researchers discover clue to how to protect neurons and encourage their growth
Researchers have identified a family of enzymes whose inhibition both protects neurons and encourages their growth, a pathway to potential new treatments for neurodegenerative diseases from Alzheimer's to glaucoma. (2020-12-14)

Development of the first biohybrid artificial retina built with silk fibroin and retinal cells.
An international research led by the Complutense University of Madrid has taken a further step to solve Age-related Macular Degeneration (AMD)-derived blidness problem with the development of the first biohybrid artificial retina built with silk fibroin and retinal cells. (2020-12-11)

Researchers say we're watching the world go blind
Three University of Michigan researchers say eye care accessibility around the globe isn't keeping up with an aging population, posing challenges for eye care professionals over the next 30 years. (2020-12-07)

Drug for rare disorder shows promise for treating herpes viruses
New research shows that the antiviral activity of the drug -- called phenylbutyrate, or PBA -- was even better when used along with acyclovir, a common HSV-1 treatment. When used in combination, less acyclovir is needed to effectively suppress the virus compared to acyclovir alone -- this is important because acyclovir is also known to have toxic side effects in the kidneys. (2020-12-07)

High-definition brain prosthesis demonstrates artificial shape perception in monkeys
An implant packed with more than 1000 tiny, brain-stimulating electrodes generates recognizable perceptions of motion and complex shapes - including letters of the alphabet - in a monkey's mind. (2020-12-03)

Household-grown food leads to improved health for children
Children grow taller in rural households where their mothers are supported to grow their own food - according to new research from the University of East Anglia (UEA). The research, which looked at households in low- and middle-income countries, showed growing their own food helped mothers to prevent stunting, wasting and underweight in their children. Their children's food was more varied, meaning they had access to different classes of food nutrients. (2020-12-03)

Targets for avoidable sight loss 'not being met': 30-year study finds
A new global study has found no significant reduction in the number of people with treatable sight loss since 2010. (2020-12-01)

Stem cell-based screen identifies potential new treatments
In a recent study published in Stem Cell Reports, Seba Almedawar, PhD, and colleagues with the Center for Regenerative Therapies TU Dresden, Germany, used induced pluripotent stem cells (iPSCs) derived from the skin of healthy donors and of patients with retinitis pigmentosa to find drugs with the potential to enhance RPE phagocytosis. (2020-11-25)

Monitoring glaucoma at home
Glaucoma is a chronic condition that affects cells at the back of the eye. It is the leading cause of irreversible blindness worldwide. People with glaucoma, or at risk of developing glaucoma, require lifelong monitoring, including regular eye tests to track the progression of the disease. A study from City, University of London is the first in the world that suggests glaucoma eye tests can be performed accurately at home by patients themselves. (2020-11-20)

Missing the radiological forest for the trees
Even experienced radiologists, when looking for one abnormality, can completely miss another. The results, published in Psychonomic Bulletin & Review, show that inattentional blindness can befall even experts. (2020-11-18)

Prejudice, poverty, gender - illustrations show the reality of living with disease
Illustrations by a local artist in Nigeria have helped highlight the prejudice, barriers and stigma experienced by people living with diseases. Born from a research project, the cartoons are helping health workers and policy makers understand what it's really like to live with a neglected tropical disease (2020-11-05)

Technique to regenerate optic nerve offers hope for future glaucoma treatment
Scientists have used gene therapy to regenerate damaged nerve fibres in the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the leading causes of blindness worldwide. (2020-11-05)

Study identifies pitfall for correcting mutations in human embryos with CRISPR
The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at earliest stage of human development. (2020-10-29)

Common treatment for diabetic macular edema not effective in Black individuals
A medication frequently used to treat diabetic macular edema, which is the most common cause of blindness in people with diabetes, is less effective when used to treat the condition in Black patients, new study results show. (2020-10-22)

UCI-led study reveals restoration of retinal and visual function following gene therapy
A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease. (2020-10-19)

Quarter of partially-sighted have unmet needs
Almost a quarter of people with severe sight loss in the UK are going without the treatment they need, according to a new study being presented at the World Congress on Public Health today (2020-10-16)

Discovery holds potential for reversing vision loss
Scientists at the Oklahoma Medical Research Foundation have identified a compound that could reverse the vision loss that occurs when blood vessels in the eyes of premature infants and adults grow out of control. (2020-10-05)

Seeing the eye like never before
In a big step for ophthalmology, scientists created a method to view the inner workings of the eye and its diseases at the cellular level. Currently, researchers can only see a broad section of the retina. This new technology allows them to zoom into just one part of a cell. In their words, they have accelerated the process for vision restoration. (2020-09-10)

Gene therapy: Novel targets come into view
Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that targeted activation of genes of similar function can compensate for the primary defect. (2020-09-02)

A healthy lifestyle for cardiovascular health also promotes good eye health
In a new study, investigators found that ideal cardiovascular health, which is indicative of a healthy lifestyle, was associated with lower odds for ocular diseases especially diabetic retinopathy. These findings appearing in The American Journal of Medicine, published by Elsevier, suggest that interventions to prevent cardiovascular diseases may also hold promise in preventing ocular diseases. (2020-08-20)

Heavy class A drug use linked to heightened risk of sight loss in US military
Heavy use of class A drugs, such as heroin, methamphetamine, or cocaine is linked to a heightened risk of partial or total blindness among US military personnel, finds research published online in the journal BMJ Military Health. (2020-08-13)

Energy demands limit our brains' information processing capacity
Our brains have an upper limit on how much they can process at once due to a constant but limited energy supply, according to a new UCL study using a brain imaging method that measures cellular metabolism. (2020-08-03)

Study finds that special filters in glasses can help the color blind see colors better
A new UC Davis Eye Center study, conducted in collaboration with France's INSERM Stem Cell and Brain Research Institute, found that special patented glasses engineered with technically advanced spectral notch filters enhance color vision for those with the most common types of red-green color vision deficiency ('anomalous trichromacy'). Notably, the ability to identify and experience expanded color was also demonstrated when color blind test subjects were not wearing the glasses. (2020-07-13)

More than meets the eye
New findings reframe the traditional view of face blindness as a disorder arising strictly from deficits in visual perception of facial features. Findings suggest prosopagnosia may be a more complex disorder rooted in multiple deficits. Findings can help inform the design of tools to improve face recognition in those with the condition. (2020-07-10)

Machine learning helps grow artificial organs
Researchers from the Moscow Institute of Physics and Technology, Ivannikov Institute for System Programming, and the Harvard Medical School-affiliated Schepens Eye Research Institute have developed a neural network capable of recognizing retinal tissues during the process of their differentiation in a dish. Unlike humans, the algorithm achieves this without the need to modify cells, making the method suitable for growing retinal tissue for developing cell replacement therapies to treat blindness and conducting research into new drugs. (2020-07-07)

Nanotechnology applied to medicine: The first liquid retina prosthesis
Researchers at Istituto Italiano di Tecnologia has led to the development of an artificial liquid retinal prosthesis to counteract the effects of diseases such as retinitis pigmentosa and age-related macular degeneration that cause the progressive degeneration of photoreceptors of the retina, resulting in blindness. The collected data show that this innovative technique is valid to restore the photoreceptive capacity of retinal neurons while preserving their spatial resolution, laying a solid foundation for future clinical trials in humans. (2020-06-29)

Scientists rescue mini retinas from eye disease via new gene therapy approach
Scientists have developed a new gene therapy approach that offers tremendous promise for one day treating an eye disease that leads to blindness and affects thousands of people across the globe. (2020-06-11)

Retinitis pigmentosa research probes role of the enzyme DHDDS in this genetic disease
Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, expected to see retinal degeneration and retinal thinning. As reported in the journal Cells, they surprisingly found none, calling into question the commonly accepted -- though never proved -- mechanism for RP59. (2020-06-11)

Restoring vision by gene therapy
Latest scientific findings give hope for people with incurable retinal degeneration. (2020-06-04)

Vision loss influences perception of sound
People with severe vision loss can less accurately judge the distance of nearby sounds, potentially putting them more at risk of injury. (2020-06-03)

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