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Integrated anemia-SCD test demonstrates accurate results in study at 2020 ASH meeting
Researchers from Case Western Reserve University presented research today in which Hemex Health's affordable Gazelle platform diagnostic technology successfully tested 46 patients with 100% sensitivity and over 92.3% specificity for anemia and with 100% accuracy for hemoglobin variants. The preliminary study included blood samples collected from Cleveland-area patients studied for anemia and sickle cell disease. (2020-12-05)

Identifying markers of COVID-19 infection using blood tests
This study identifies the values for six biochemical biomarkers that indicate a patient may be infected with SARS-COV-2 (COVID-19). The key novelty of this study lies in the fact that it was carried out using a blood test and can provide a determination in about 60 minutes. (2020-12-04)

New study debunks blood type diet
A study published in the Journal of the Academy of Nutrition and Dietetics by researchers with the Physicians Committee for Responsible Medicine -- a nonprofit of 12,000 doctors -- debunks the 'blood type diet' by finding that blood type was not associated with the effects of a plant-based diet on body weight, body fat, plasma lipid concentrations, or glycemic control. (2020-12-04)

Researchers adapt cell phone camera for SARS-CoV-2 detection
Researchers have developed an assay that can detect the presence of SARS-CoV-2 in a nasal swab using a device attached to an ordinary smartphone, they report December 4 in the journal Cell. Although more research is needed before such a test can be rolled out, the results are promising and ultimately may be applicable to screening more broadly for other viruses. (2020-12-04)

Comparison of coronavirus antibody tests revealed too optimistic claims
A study by University of Tartu researchers indicates that the sensitivity of tests used to detect viral antibodies in a blood sample may differ significantly. The combination of several tests may give the best result. (2020-12-03)

Better diabetes treatment: New insulin molecule can self-regulate blood sugar
Researchers from the University of Copenhagen and biotech firm Gubra have developed a new insulin molecule that will make blood sugar regulation both easier and safer for those with type 1 diabetes. (2020-12-03)

New lab-on-a-chip infection test could provide cheaper, faster portable diagnostics
A tiny new silicon-based lab-on-chip test could pave the way for cheap handheld infectious disease testing. (2020-12-02)

Out of many COVID-19 tests, which one to choose?
Curbing the coronavirus pandemic relies heavily on how quickly a potentially exposed individual can be tested and quarantined. However, the current diagnostic techniques vary in reliability and relevance, so an understanding of which test is most appropriate for a given circumstance is necessary to avoid false reports. Researchers evaluated the available diagnostic techniques and determined key steps required for better testing moving forward. They present their findings in the journal APL Bioengineering. (2020-12-01)

Can drinking cocoa make you smarter?
Increased consumption of flavanols - a group of molecules which occur naturally in fruit and vegetables - can increase your mental agility, according to new research at the University of Birmingham. (2020-11-24)

Biofriendly protocells pump up blood vessels
In a new study published today in Nature Chemistry, Professor Stephen Mann and Dr Mei Li from Bristol's School of Chemistry, together with Associate Professor Jianbo Liu and colleagues at Hunan University and Central South University in China, prepared synthetic protocells coated in red blood cell fragments for use as nitric oxide generating bio-bots within blood vessels. (2020-11-20)

For COVID-19 surveillance, test frequency and turnaround time are paramount, modeling suggests
Speed of test results and frequency of testing are paramount for effective COVID-19 surveillance, suggests a new study that modeled trade-offs in test sensitivity, test frequency, and sample-to-answer reporting time, in select scenarios. Test sensitivity is secondary to these factors in the scenarios studied. (2020-11-20)

Three reasons why COVID-19 can cause silent hypoxia
To crack the mystery of what causes silent hypoxia, a condition when oxygen levels in the body are abnormally low, BU biomedical engineers used computer modeling to test out three different scenarios that help explain how and why the lungs stop providing oxygen to the bloodstream. (2020-11-19)

Suffering in silence: two-thirds of older adults say they won't treat their depression
A new nationwide poll, the GeneSight Mental Health Monitor, shows that nearly two-thirds (61%) of Americans age 65 or older who have concerns about having depression will not seek treatment. In fact, nearly 1 in 3 (33%) seniors who are concerned they might be suffering from depression believe they can ''snap out'' of it on their own. (2020-11-16)

New saliva-based antibody test for SARS-CoV-2 highly accurate in initial study
A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19. (2020-11-13)

Protein in blood may predict prognosis, recovery from stroke
Researchers at Mayo Clinic in Florida and collaborators have found that a biomarker in the blood may determine the extent of brain injury from different types of strokes and predict prognosis in these patients. Their findings are reported in Science Translational Medicine. (2020-11-11)

Accuracy of rapid COVID test may be lower than previously suggested
The accuracy of a rapid finger-prick antibody test for SARS-CoV-2, the virus responsible for covid-19 infection, may be considerably lower than previously suggested, finds a study published by The BMJ. (2020-11-11)

Postpartum care fails to provide women with key recommended services
Most women are receiving fewer than half the services recommended during their comprehensive postpartum medical checkup, according to a study by University of Massachusetts Amherst researchers. (2020-11-10)

For quick COVID-19 testing, iSCAN can
A new test kit could enable quick and effective COVID-19 tests for people arriving at airports. (2020-11-05)

Blood cell mutations confound prostate cancer liquid biopsy results
Unrelated mutations, when present in the blood, can give false positive results in men with advanced prostate cancer undergoing liquid biopsies. Such tests, which look for variants in cell-free DNA that tumors shed into the blood plasma, help determine suitable treatment options. Incorrect test results might mean the patient gets therapies unsuited for his cancer. A simple solution overcomes this problem. (2020-11-05)

USask researchers find face masks don't hinder breathing during exercise
A new University of Saskatchewan (USask) study has found that exercise performance and blood and muscle oxygen levels are not affected for healthy individuals wearing a face mask during strenuous workouts. (2020-11-05)

COVID-19 linked to worse stroke outcomes
People who experience strokes while infected with COVID-19 appear to be left with greater disability after the stroke, according a study led by UCL and UCLH researchers. (2020-11-05)

Stanford engineers have developed a genetic microlab that can detect COVID-19 in minutes
The microlab test takes advantage of the fact that coronaviruses like SARS-COV-2, the virus that causes COVID-19, leaves behind tiny genetic fingerprints wherever they go in the form of strands of RNA, the genetic precursor of DNA. If the coronavirus's RNA is present in a swab sample, the person from whom the sample was taken is infected. (2020-11-04)

Malaria test as simple as a bandage
A test for malaria looks like a bandage, but can diagnose the disease in minutes without the need for medical expertise or specialized equipment. (2020-11-02)

Radical diagnostic could save millions of people at risk of dying from blood loss
Engineers at Monash University in Australia have developed a fast, portable and cheap diagnostic that can help deliver urgent treatment to people at risk of dying from rapid blood loss. This portable diagnostic measures fibrinogen concentration in blood. (2020-10-29)

Early indications of thrombosis help in preventing postoperative complications
It is well-known that surgeries can be complicated by life-threatening thromboses that are hard to predict and not easy to prevent. The authors managed to find a new prognostic laboratory sign of the imminent postoperative thrombosis; remarkably, this sign appears on the first postoperative day, a few days before deep vein thrombosis of the lower limbs develops. (2020-10-27)

COVID-19: Call for millions spent on failing system to be diverted to local services
A group of doctors is calling on the government to divert the hundreds of millions of pounds being spent on the failing centralised privatised COVID-19 national test and trace service into local primary care, local NHS labs and local public health services. (2020-10-27)

People with type 2 diabetes need not avoid eating potatoes based on glycemic index
People with type 2 Diabetes (T2D) are frequently told to avoid eating potatoes, and other high Glycemic Index (GI) foods, because of the longstanding perception that these foods make it difficult to control blood sugar levels. However, for the first time, a rigorously controlled clinical trial, including 24 adults with T2D, demonstrates that GI is not an accurate surrogate for an individual's glycemic response (GR) to a food consumed as part of an evening meal. (2020-10-26)

New experimental blood test determines which pancreatic cancers will respond to treatment
Scientists have developed a simple, experimental blood test that distinguishes pancreatic cancers that respond to treatment from those that do not. This critical distinction could one day guide therapeutic decisions and spare patients with resistant cancers from undergoing unnecessary treatments with challenging side effects. The findings were published today in Clinical Cancer Research, a journal of the American Association for Cancer Research. (2020-10-22)

Hackensack Meridian CDI, University of Michigan show faster COVID-19 antibody test
A new portable ''lab on a chip,'' developed by the U-M scientists and demonstrated with help of the CDI, can identify the presence of COVID-19 antibodies in blood donors with greater speed and efficiency than the current standard (2020-10-22)

Scientist develops new way to test for COVID-19 antibodies
New research details how a cell-free test rapidly detects COVID-19 neutralizing antibodies and could aid in vaccine testing and drug discovery efforts. (2020-10-22)

Ketamine, a painkiller used by the army, does not impair tolerance to blood loss
A low dose of ketamine, administered intravenously, does not alter a healthy human's tolerance to blood loss. In other words, if someone was given ketamine to kill pain associated with a battlefield injury, they would be able to tolerate blood loss just as well as someone who did not received this pain killer. (2020-10-21)

Brigham researchers make strides in detecting preeclampsia risk
To improve early detection of preeclampsia risks and better classify potential subtypes of the disease, a team led by researchers from Brigham and Women's Hospital analyzed an array of maternal and placental proteins, identifying several biomarkers that, from a blood sample drawn at 12 weeks gestation, can help predict the risk of preeclampsia and, equally importantly, can assess who may develop more severe forms of the condition. (2020-10-21)

Researchers identify genetic variants linked to toxic side effects from bevacizumab
In the largest study of its kind, researchers have found two common genetic variants that can be used to predict whether or not cancer patients might suffer severe adverse side-effects, such as high blood pressure, from the drug bevacizumab. The genome-wide association study is the largest such study in patients being treated with bevacizumab and it is to be presented at the 32th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. (2020-10-21)

Researchers develop method for earlier detection of Alzheimer's Disease
Washington State University scientists have developed a method to detect the biomarkers for Alzheimer's disease that is 10 times more sensitive than current blood testing technology. (2020-10-20)

New method allows more targeted measurement of thyroid hormone action in tissue
A team led by Michael Krebs from MedUni Vienna's Division of Endocrinology and Metabolism has now conducted a study to test the use of magnetic resonance spectroscopy (NMRS) to measure the effect in body tissue as well. They were able to identify certain phosphorus-containing compounds that are visible in NMRS as markers for thyroid hormone action in tissue. The study has been published in the prestigious ''Journal of Clinical Endocrinology and Metabolism''. (2020-10-20)

New tool pulls elusive COVID-19 marker from human blood
Researchers at McMaster University and SQI Diagnostics in Canada have created a surface that repels every other element of human blood except an elusive cytokine critical to understanding the progress of COVID-19 in individual patients. (2020-10-20)

Nature Communications publishes Bluestar Genomics' technology for cancer detection study
Bluestar Genomics, an innovative company leading the development of next-generation epigenomic approaches to early cancer detection, announced today the publication of study results in the peer-reviewed journal Nature Communications. The study demonstrates the power of the company's platform to detect pancreatic cancer in its early stages, addressing the unmet need of more than 60,000 patients diagnosed with the disease each year in the United States alone. (2020-10-20)

Hand-held device reads levels of cancer biomarker
Researchers at McMaster and Brock universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing. (2020-10-19)

New evidence to guide the practice of blood transfusions in children with severe malari
Blood transfusions increase the survival of children admitted to the hospital with complications by severe malaria, and could be beneficial even at higher haemoglobin levels than those currently recommended. These are the main findings of a study led by ISGlobal, a centre supported by ''la Caixa'' Foundation, and published in The Lancet Haematology. (2020-10-19)

Standalone D-dimer test strategy may simplify diagnosis of deep vein thrombosis
New research suggests that it may be possible to simplify the diagnosis of deep vein thrombosis (DVT) without compromising accuracy. Contrary to the standard practice of administering several tests to diagnose DVT, using only a D-dimer blood test may help health care providers identify patients who require additional screening, according to a new study in Blood Advances. (2020-10-15)

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