Current Bowel Cancer News and Events | Page 2

Current Bowel Cancer News and Events, Bowel Cancer News Articles.
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Oral contraceptive pills protect against ovarian and endometrial cancer
A comprehensive study from Uppsala University, involving more than 250,000 women, shows that oral contraceptive use protects against ovarian and endometrial cancer. The protective effect remains for several decades after discontinuing the use. The study is published in the journal Cancer Research. (2020-12-17)

Study finds paediatric cancer patients at no greater risk of severe COVID-19 infection
Children with cancer who test positive for COVID-19 do not appear to be at an increased risk of severe COVID-19 infection compared to healthy children, according a new UK study. (2020-12-14)

New treatment could spare early-stage rectal cancer patients life-altering side effects
A new and less invasive treatment developed by Cancer Research UK researchers is safer than standard major surgery for early-stage rectal cancer, giving patients a better quality of life with fewer life-altering side effects, results from a pilot study show. (2020-12-10)

Nearly 72% of Black patients with gynecologic cancer and COVID-19 were hospitalized for the virus compared with 46 percent of non-Blacks
COVID-19 deaths among Black patients with gynecologic cancer disproportionately higher compared to non-Black patients. (2020-12-09)

High-risk, HR+, HER2-, early-stage BC patients continue to benefit from abemaciclib
Extended follow-up data from the phase III monarchE trial showed that adding the cyclin-dependent kinase (CDK) inhibitor abemaciclib (Verzenio) to standard adjuvant endocrine therapy continued to improve invasive disease-free survival (IDFS) among patients with high-risk, node-positive, early-stage, HR-positive, HER2-negative breast cancer, according to data presented at the 2020 San Antonio Breast Cancer Symposium. (2020-12-09)

New guidelines for treating the complications of brain tumours
Experts from the leading oncology societies ESMO (European Society for Medical Oncology) and EANO (European Association of Neuro-Oncology) hav now compiled international guidelines and standards for the treatment of complications of brain tumours (2020-12-09)

New treatment in development for irritable bowel syndrome with constipation
Researchers devised a plan to treat IBS with constipation by delivering chenodeoxycholic acid in a bilayered capsule, finding that this mode of delivery could decrease colon cramping and thus produce a better patient experience. (2020-12-08)

Researchers create framework to help determine timing of cancer mutations
UCLA researchers studying cancer evolution have created a framework to help determine which tool combinations are best for pinpointing the exact timing of DNA mutations in cancer genomes. (2020-12-07)

AI predicts which drug combinations kill cancer cells
A machine learning model developed in Finland can help us treat cancer more effectively. (2020-12-01)

Oncotarget launches special collection on breast cancer
Breast Cancer Collection published in honor of breast cancer awareness. (2020-12-01)

Vitamin D regulates calcium in intestine differently than previously thought
A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role. The findings have important implications on how bowel disease, including ulcerative colitis and Crohn's disease, may disrupt calcium regulation. (2020-12-01)

Specific bacterium in the gut linked to irritable bowel syndrome (IBS)
Researchers at the University of Gothenburg have detected a connection between Brachyspira, a genus of bacteria in the intestines, and IBS -- especially the form that causes diarrhea. Although the discovery needs confirmation in larger studies, there is hope that it might lead to new remedies for many people with irritable bowel syndrome. (2020-11-25)

For African American men with prostate cancer, decision regret linked to medical mistrust
Medical mistrust is one reason why African American patients are more likely to have regrets about their choice of treatment for prostate cancer, suggests a study in The Journal of Urology®, Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. (2020-11-24)

Brain protein could be starting point for new treatments for pancreatic cancer
Researchers have discovered that a protein thought to only be involved in the development of neurons in the brain also plays a major role in the development and growth of pancreatic cancer. Their findings demonstrate for the first time how the protein, called Netrin-G1, helps pancreatic cancer cells survive by protecting them from the immune system and supplying them with nutrients. (2020-11-18)

Existing antidepressant helps to inhibit growth of cancer cells in lab animals
New research has shown that the antidepressant sertraline helps to inhibit the growth of cancer cells. The substance acts on a metabolic addiction that allows different types of cancer to grow. This is shown by a study on cell cultures and lab animals by researchers at KU Leuven. (2020-11-17)

Study pinpoints target for managing inflammation, promoting tissue repair
Drugs that can manage the activity of a protein called BCAP could help the body repair IBD-related tissue damage caused by inflammation, according to experts at Cincinnati Children's. (2020-11-16)

State-level lung cancer screening rates not aligned with lung cancer burden in the US
A new study reports that state-level lung cancer screening rates were not aligned with lung cancer burden. (2020-11-12)

Genetic risk for fatal blood clots identified in IBD patients
In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases. (2020-11-11)

New analysis finds lung cancer screening reduces rates of lung cancer-specific death
Low-dose CT screening methods may prevent one death per 250 at-risk adults screened, according to a meta-analysis of eight randomized controlled clinical trials of lung cancer screening. Researchers at the University of Georgia analyzed the health outcomes of 90,275 patients, comparing those who were screened versus those who received usual medical care or chest x-rays. (2020-11-10)

People with inflammatory bowel disease still die earlier despite increase in life
A study comparing life expectancy of people with inflammatory bowel disease (IBD) and without found that, while life expectancy increased for both groups, people with IBD generally died sooner. The study is published in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/lookup/doi/10.1503/cmaj.190976. (2020-11-09)

COVID-19: Enzyme targeted by virus also influences gut inflammation
An enzyme that helps COVID-19 (coronavirus) infect the body also plays a role in inflammation and patient outcomes in inflammatory bowel disease (IBD), according to a new study led by Cedars-Sinai. The findings raise the possibility that anti-inflammatory drug therapies for IBD may aid recovery from coronavirus. (2020-11-05)

Review finds almost 20% of COVID-19 patients only show gastrointestinal symptoms
Almost one in five patients with COVID-19 may only show gastrointestinal symptoms, according to a review of academic studies published in the journal Abdominal Radiology. The findings of the review suggest abdominal radiologists need to remain vigilant during the pandemic while imaging patients. (2020-11-03)

Active surveillance safe for African Americans with low-risk prostate cancer
Researchers with UC San Diego School of Medicine and Moores Cancer Center say active surveillance is safe for African American men with low-risk prostate cancer. (2020-11-03)

Validation of ERCC1/2 signature as radiosensitivity biomarker for tumor & normal tissues in NSCLC
A genetic analysis of non-small cell lung cancer (NSCLC) patients on the phase III NRG Oncology RTOG 0617 clinical trial assessing radiation dose discovered that high dose radiation therapy is associated with shorter survival times among patients with a radiation-sensitive genotype in DNA repair pathway. These findings were presented at the virtual edition of the American Society for Radiation Oncology's (ASTRO) Annual Meeting in October 2020. (2020-10-28)

Outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer
Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants. (2020-10-28)

Some rectal cancer patients can safely avoid an aggressive operation
A nonsurgical treatment option for rectal cancer that preserves quality of life is safe for carefully selected patients, according to a new study comparing it with the standard operation. The study results appear online as an 'article in press' on the Journal of the American College of Surgeons website in advance of print publication and were presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

MFS Is a strong surrogate endpoint for OS for men receiving salvage RT for recurrent prostate cancer
An analysis of the phase III NRG Oncology clinical trial RTOG 9601 on men receiving salvage radiotherapy (SRT) following prostatectomy for recurrent prostate cancer indicated that, while biochemical failure (BF) was not a strong surrogate endpoint to determine overall survival (OS), metastasis-free survival (MFS) was in this patient population. (2020-10-26)

Effectiveness of gemcitabine & daily RT for bladder preservation in muscle-invasive bladder cancer
Bladder preservation with trimodality therapy can be a safe and effective alternative to cystectomy for selected patients with muscle-invasive bladder cancer. The phase II NRG Oncology NRG-RTOG 0712 trial evaluated two regimens. One was the prior RTOG standard using 5-flourouracil and cisplatin with twice daily radiation (FCT), and the other a regimen of gemcitabine and daily radiation (GD) which had demonstrated efficacy in single institution clinical trials. (2020-10-26)

Gut bacteria associated with animal-based diet may mitigate risk of cardiovascular disease
Researchers have found that a type of common gut bacteria sometimes associated with inflammation, abscesses, bowel disease and cancer has a major silver lining: It seems to help prevent cardiovascular disease. (2020-10-26)

Next generation BRAF inhibitor cancer drug shows promise in early patient trial
A new drug designed to work on cancers with an altered BRAF gene has shown promise in an early patient trial presented at the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online. (2020-10-25)

Easy home cancer test means patients can avoid hospital for colonoscopies
Findings from the largest international research study found that using FIT is almost 100% accurate at ruling out bowel cancer in patients with suspicious symptoms. During COVID, cancer diagnostics services were suspended and continue to be disrupted. Clinicians in London, along with NHS England, London region, agreed to rapidly implement the use of the same easy home test used in the bowel cancer screening programme, the FIT (faecal immunochemical test), to rule out cancer in people with suspected symptoms. (2020-10-23)

Achieving high concentrations of sunitinib in tumors is linked to improved survival
A strategy for giving intermittent, high doses of the anti-cancer drug sunitinib is well-tolerated by patients with advanced cancer and increases concentrations of the drug in tumors, which is associated with improved survival, according to research to be presented at the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online. (2020-10-23)

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications. (2020-10-22)

Discoveries reshape understanding of gut microbiome
The findings redefine how the so-called gut microbiome operates and how our bodies coexist with some of the 100 trillion bacteria that make it up. The discoveries could lead to new therapies for inflammatory bowel disease and people who've had portions of their bowels removed due to conditions like colon cancer and ulcerative colitis. They also help explain why the use of antibiotics can create a multitude of problems in the digestive system. (2020-10-22)

Vaccine to treat and prevent lung, bowel and pancreatic cancer shows promise in the lab
An experimental vaccine, designed to enlist the body's own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice. The vaccine was created to target a gene called KRAS that is involved in the development of many types of cancer, including lung, bowel and pancreatic cancer. (2020-10-22)

Cholesterol medications linked to lower cancer-related deaths in women
Among women with breast cancer, colorectal cancer, or melanoma, those who were taking cholesterol-lowering medications, were less likely to die from cancer, according to an analysis published in the British Journal of Clinical Pharmacology. (2020-10-21)

Rutgers finds new way to personalize treatments for prostate cancer
Rutgers researchers have discovered human gene markers that work together to cause metastatic prostate cancer - cancer that spreads beyond the prostate. (2020-10-19)

Novel mechanical mechanism of metastatic cancer cells in substrates of different stiffness revealed
Metastasis, the spread of cancer cells to a different body part from where it started, is considered as the most dangerous phase of cancer development. When cancer cells break away from the main tumor and enter the bloodstream or lymphatic system, they can travel to anywhere of the body, proliferate and creating a secondary tumor in a new location. It is often said that metastasis is responsible for around 90% of cancer deaths. (2020-10-16)

Study finds room for improvement when hospital patients transition to hospice care
Terminally ill patients referred to hospice care from a hospital setting tend to be on hospice for shorter periods than those who enter hospice while living at home or in a residential care facility. (2020-10-16)

Neural crest cell migration in Hirschsprung disease
Ankush Gosain, MD, PhD, of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous system in Hirschsprung disease. Gosain recently published a new study in The FASEB Journal. (2020-10-13)

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