Current Bowel Cancer News and Events | Page 25

Current Bowel Cancer News and Events, Bowel Cancer News Articles.
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Among colon cancer patients, smokers have worse outcomes than non-smokers
In an analysis of more than 18,000 patients treated for colon cancer, current smokers were 14 percent more likely to die from their colon cancer within five years than patients who had never smoked. Among patients treated by surgery only, current smokers were 21 percent more likely to die from their colon cancer than patients who had never smoked. (2017-02-08)

Cancer survivors find online and phone communication with medical professionals beneficial
Coinciding with World Cancer Day (Feb. 4), researchers from the School of Health Sciences at the University of Surrey have completed the first ever systematic review of cancer survivors' experience of online and telephone telehealth interventions in cancer care, a new study in the Journal of Medical Internet Research reports. (2017-02-02)

UT Southwestern researchers identify gene that protects against inflammatory bowel disease
UT Southwestern Medical Center researchers have identified a gene that protects the gut from inflammatory bowel disease (IBD). The mouse study found a mutation in the Gatm gene and used CRISPR/Cas9 gene-editing technology to confirm this link. The Gatm gene is required for the rapid replenishment of the intestinal mucosal barrier that guards the intestinal wall against inflammation caused by bacteria in the digestive tract, researchers determined. (2017-02-01)

Why thick skin develops on our palms and soles, and its links to cancer
Scientists from Queen Mary University of London have discovered that foot callouses/keratoderma (thickened skin) can be linked to cancer of the esophagus (gullet), a disease which affects more than 8,000 people in the UK each year. (2017-02-01)

Changes in gene contribute independently to breast and ovarian cancer
Defects in the EMSY gene -- long thought to drive cancer by turning off the protection afforded by the BRCA genes -- spur cancer growth on their own. (2017-01-31)

Silencing cancer cell communication may reduce the growth of tumors
In this issue of the JCI, a study led by Frances Balkwill at Barts Cancer Institute evaluated whether blocking cancer cell communication through the CCR4 receptor could reverse the pro-tumor environment in a mouse model of cancer. (2017-01-30)

Largest genetic study of inflammatory bowel disease provides clues on new drug targets
In two studies published Jan. 30 in Nature Genetics, researchers from the Wellcome Trust Sanger Institute and their collaborators have identified a genetic variant that doubles an individual's risk of developing ulcerative colitis, one of the subtypes of a chronic disorder known as inflammatory bowel disease. (2017-01-30)

Breath test could help detect stomach and esophageal cancers
A test that measures the levels of five chemicals in the breath has shown promising results for the detection of cancers of the esophagus and stomach, according to research presented at the European Cancer Congress 2017. (2017-01-29)

Researchers help the body protect itself against inflammation and colon cancer
Virginia Tech researchers found that modifying the shape of IRAK-M, a protein that controls inflammation, can significantly reduce the clinical progression of both diseases in pre-clinical animal models. (2017-01-27)

Short bowel syndrome results in changes to gene expression
Investigators at Children's Hospital Los Angeles, led by Tracy C. Grikscheit, M.D., have mapped the genetic changes resulting from short bowel syndrome using a novel zebrafish model and by performing intensive gene sequencing. (2017-01-25)

Anxiety and depression may be linked to increased risk of death from some cancers
A study published by The BMJ today suggests that higher levels of psychological distress (anxiety and depression) may be associated with an increased risk of death from certain cancers. (2017-01-25)

Lung cancer patients with anxiety, depression die sooner: Study
Patients who experience anxiety and depression after being diagnosed with advanced lung cancer are more likely to die sooner, according to new research from the University of British Columbia and BC Cancer Agency. (2017-01-24)

U-M researchers discover what makes drug for ulcerative colitis tick
For approximately 70 years, physicians have used a medication containing the active agent mesalamine to treat ulcerative colitis, but little was known about how the drug targeted the inflammatory bowel disease. (2017-01-23)

Positive outcomes after obesity surgery in adolescents
Obesity surgery has proven to be just as effective for teenagers as for adults. Five years on, those who underwent the procedure as teenagers weighed, on average, 28 percent less than prior to the surgery. There were, however, complications associated with this type of surgery the new study shows. (2017-01-23)

'FishTaco' sorts out who is doing what in your microbiome
How much do different bacterial species contribute to disease-associated imbalances in the human microbiome? A new computational method, dubbed FishTaco, is helping find out. The method looks at which microbes are present and what they are doing. Understanding imbalances in say, the human gut microbiome, might eventually suggest new ways to manage obesity, type 2 diabetes, or autoimmune diseases. (2017-01-19)

Affordable Care Act made cancer screening more accessible for millions, study finds
From 2011 to 2013, the ACA resulted in an 8 percent increase in the diagnoses of early-stage colorectal cancer among US seniors aged 65 and older. (2017-01-18)

Northwell Health's Feinstein Institute discovers cancer treatment for transplant patients
Kenar D. Jhaveri, M.D., and Richard Barnett, M.D., Feinstein Institute for Medical Research scientists and Northwell Health Department of Internal Medicine nephrologists, published a Letter to the Editor in the prestigious New England Journal of Medicine, which profiles a novel drug combination with the potential to help prevent rejection of a donor kidney in transplant patients undergoing cancer treatment. (2017-01-18)

'Pedal bin machine' of gut bacteria revealed
Researchers shed new light on the functioning of human gut bacteria, revealing how nutrients are transported into the bacterial cell. (2017-01-11)

The importance of the glutamine metabolism in colon cancer
The importance of glutamine was made clear as a colon cancer specific metabolism. It is known that glutamine metabolism is important for pancreatic cancer, but the importance of glutamine metabolism for colon cancer has been unclear. In this study, we showed the importance of glutamine metabolism. (2017-01-10)

Researchers reveal how cancer cells cope with genetic chaos
Scientists have uncovered how tumors are able to grow despite significant damage to the structure and number of their chromosomes, the storage units of DNA. (2017-01-09)

Crohn's disease risk and prognosis determined by different genes, study finds
Researchers have identified a series of genetic variants that affect the severity of Crohn's disease, an inflammatory bowel disease -- but surprisingly, none of these variants appear to be related to an individual's risk of developing the condition in the first place. (2017-01-09)

Mayo Clinic researchers identify new potential treatment for cancer metastasis
Breast cancer metastasis, the process by which cancer spreads, may be prevented through the new use of a class of drugs already approved by the US Food and Drug Administration. (2017-01-09)

IBS affects women's quality of life more than men's
Double work and a high embarrassment factor can lead to the quality of life being affected more among women than men by irritable bowel syndrome (IBS), a very common gastrointestinal disease. Even with the same level of physical pain and other symptoms, women's perceived quality of life is worse than the men's, according to new research. (2017-01-09)

Place matters in late diagnosis of colorectal cancer, study finds
In addition to a person's race or ethnicity, where they live can matter in terms of whether they are diagnosed at a late stage for colorectal cancer, according to a recent study led by a researcher at the School of Public Health at Georgia State University. (2017-01-09)

Has the Affordable Care Act reduced socioeconomic disparities in cancer screening?
Out-of-pocket expenditures are thought to be a significant barrier to receiving cancer preventive services, especially for individuals of lower socioeconomic status. A new study looks at how the Affordable Care Act (ACA), which eliminated such out-of-pocket expenditures, has affected the use of mammography and colonoscopy. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study found that use of mammography, but not colonoscopy, increased after the ACA. (2017-01-09)

Lung cancer patients may benefit from delayed chemotherapy after surgery
A new Yale study suggests that patients with a common form of lung cancer may still benefit from delayed chemotherapy started up to four months after surgery, according to the researchers. The study was published online by JAMA Oncology on Jan. 5, 2017. (2017-01-05)

Enzyme could protect against type of colorectal cancer by suppressing tumors, study finds
An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study. (2017-01-03)

Gut microorganisms affect our physiology
Researchers have found evidence that could shed new light on the complex community of trillions of microorganisms living in all our guts, and how they interact with our bodies. (2016-12-29)

Gene test could pinpoint patients sensitive to new type of cancer drug
Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs, a major new study reveals. Scientists found that defects in a gene called ARID1A caused sensitivity to new drugs -- called ATR inhibitors -- targeting the DNA repair process within tumor cells. (2016-12-22)

Cancer registries in resource-constrained countries can inform policy
Data from population-based cancer registries are vital for informing health programs, policies and strategies for cancer screening and treatment. A special issue of Cancer Epidemiology, prepared under the auspices of the Centers for Disease Control and Prevention, offers lessons for planning and supporting cancer registration in resource-constrained settings to support data-driven policies on cancer prevention, early detection and appropriate treatment leading to significant cost savings for government and society as a whole. (2016-12-20)

International trial shows pelvic floor exercise benefit for preventing prolapse
Researchers, including several University of Otago academics, have conducted the first trial of pelvic floor muscle training for the prevention of prolapse symptoms in women with early signs of prolapse several years after childbirth, publishing their findings in the world's leading medical journal The Lancet. (2016-12-20)

Huntsman Cancer Institute leads international colorectal study
Huntsman Cancer Institute (HCI) at the University of Utah will head an international study to find out how lifestyle and other health factors impact colon and rectal cancer outcomes. HCI was awarded an $8.8 million grant from the National Institutes of Health to lead and expand an ongoing project in colon cancer research. (2016-12-19)

Genetic study of primary sclerosing cholangitis reveals potential drug target
Primary sclerosing cholangitis is a debilitating rare disease of the liver with no effective treatment. Reported in Nature Genetics researchers from the Wellcome Trust Sanger Institute, Mayo Clinic and their collaborators identify four regions of the genome associated with the disease, one of which is a potential drug target. (2016-12-19)

KU Leuven awards joint honorary doctorate to James P. Allison and Carl H. June
As part of its Patron Saint's Day celebrations on Feb. 15 2017, KU Leuven (Belgium) will award a joint honorary doctorate to immunologists James P. Allison (University of Texas) and Carl H. June (University of Pennsylvania). (2016-12-19)

NRG-LU001 reaches patient accrual goal
NRG Oncology clinical trial NRG-LU001 successfully reached its accrual goal of 168 patients. NRG-LU001: Randomized Phase II Trial of Concurrent Chemoradiotherapy with or without Metformin Hydrochloride (HCL) in Locally Advanced Non-Small Cell Lung Cancer (NSCLC) is the first clinical trial that seeks to determine whether metformin added to standard, concurrent chemoradiotherapy can improve progression-free survival (PFS) for patients with locally advanced NSCLC. (2016-12-16)

Gene mutations among young patients with colorectal cancer
While many patients with colorectal are diagnosed when they are older than 50, about 10 percent of patients are diagnosed at younger ages. So what is the frequency of cancer susceptibility gene mutations among patients with colorectal cancer who are diagnosed younger than 50? (2016-12-15)

New approach for cancer prevention in BRCA1 mutation-positive women from Josef Penninger
With his DoD BCRP Innovator Award, Dr. Penninger investigated whether RANKL inhibition could be used to prevent breast cancer in mouse models. (2016-12-15)

Scientists investigate cancer radiotherapy to make improvements
A University of Rochester Medical Center study shows that when tumors are treated with radiotherapy, the benefits can be hijacked by the treatment's counteraction to trigger inflammation and dampen the body's immune response. (2016-12-14)

New hopes in cancer battle -- a review of new molecules and treatment strategies
Cancer treatment is still one of the most intractable challenge for medicine. There are several approaches to fight cancer, which include: surgery, radiation therapy, chemotherapy, immunotherapy, targeted therapy and hormone therapy. From all these treatment methods, chemotherapy seems to be the most widely used. Therefore, it is understandable that scientists are trying to discover new molecules which may be applied as effective chemotherapeutics. (2016-12-14)

Enzyme that regulates DNA repair may offer new precision treatments for breast and ovarian cancer
Researchers at Mayo Clinic have identified an enzyme called UCHL3 that regulates the BRCA2 pathway, which is important for DNA repair. Results of this research are published online in Genes & Development. (2016-12-12)

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