Current Brain Tumour News and Events | Page 25

Current Brain Tumour News and Events, Brain Tumour News Articles.
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Study reveals how immune cells target different tissues
For the first time, researchers have revealed the different molecular identities of important immune cells, called T regulatory cells, in peripheral non-lymphoid tissues like skin and colon. Researchers from the Wellcome Sanger Institute and collaborators revealed that T regulatory cells have tissue-specific receptors and other adaptations, allowing them to move to the correct place. In future this could help understand how to target therapeutic cells to specific places in the body, for targeted treatments. (2019-02-05)

A breakthrough for brain tumor drug development
Glioblastoma is a devastating disease with poor survival stats due in part to a lack of preclinical models for new drug testing. To address these challenges a multidisciplinary team of researchers have developed a human relevant 3D model containing tumor and normal cells and a platform for accurate drug efficacy measurements. An experimental therapy doxorubicin (DOX) was tested and found to be more active in the model than the existing therapy. (2019-02-05)

Shared genetic marker offers new promise in targeting specific ovarian and lung cancers
Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare and one common form. (2019-02-04)

Women's brains appear three years younger than men's
Women's brains appear to be three years younger than men's of the same age, according to a new study on brain metabolism from researchers at Washington University School of Medicine in St. Louis. The findings could explain why women maintain their cognitive skills longer than men. (2019-02-04)

Simply shining light on dinosaur metal compound kills cancer cells
A new compound based on iridium, a rare metal which landed in the Gulf of Mexico 66 million years ago, hooked onto albumin, a protein in blood, can attack the nucleus of cancerous cells when switched on by light, University of Warwick researchers have found. (2019-02-03)

Skin cancer can spread in mice by hijacking the immune system
Scientists have uncovered molecules released by invasive skin cancer that reprogram healthy immune cells to help the cancer to spread. (2019-01-31)

Fight or flight: Serotonin neurons prompt brain to make the right call
Known for its role in relieving depression, the neurochemical serotonin may also help the brain execute instantaneous, appropriate behaviors in emergency situations, according to a new Cornell study published Feb. 1 in Science. (2019-01-31)

NUS study: Nanoparticles may promote cancer metastasis
Researchers from the National University of Singapore have found that cancer nanomedicine, which are designed to kill cancer cells, may accelerate metastasis. Using breast cancer as a model, they discovered that common nanoparticles made from gold, titanium dioxide, silver and silicon dioxide -- found in processed food, consumer products, and also used in nanomedicines -- widen the gap between blood vessel cells, making it easier for other cells, such as cancer cells, to go in and out of 'leaky' blood vessels. (2019-01-31)

Genetic causes of tumors in salivary glands
Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland. Until now, the molecular causes for the illness were unknown. Researchers at Universitätsklinikum Erlangen at FAU, the German Cancer Research Centre in Heidelberg and the Berlin Institute of Health have now been able to shed light on them. (2019-01-30)

New 3D imaging technique reveals how pancreatic cancers start
A new technique to study tissue samples in 3D has revealed that pancreatic cancers can start and grow in two distinct ways, solving a decades-old mystery of how tumors form. The new method could help researchers to get more information from tissue biopsies and may lead to improved treatments for pancreatic cancers. (2019-01-30)

Engineering a cancer-fighting virus
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers. (2019-01-29)

Cardiff University researchers shed light on development of gastric cancer
Cardiff University researchers have uncovered new information about the underlying mechanisms for gastric cancer, providing hope of potential new therapies in the future. (2019-01-29)

Stress and dream sleep are linked to pathways of brain cell death and survival
The first and most distinct consequence of daily mild stress is an increase in rapid-eye-movement (REM) sleep, a new study in the journal PNAS reports. The research also demonstrated that this increase is associated with genes involved in cell death and survival. (2019-01-28)

What you eat could impact your brain and memory
High levels of a satiety hormone could decrease a person's likelihood of developing Alzheimer's disease. For individuals who have higher levels of the hormone, their chance of having mild cognitive impairment or Alzheimer's disease decreased by 65 percent, according to an Iowa State University study. (2019-01-28)

Do bigger brains equal smarter dogs? New study offers answers
Larger dogs have better short-term memory and self-control than smaller breeds, according to research led by the Arizona Canine Cognition Center at the University of Arizona. (2019-01-28)

Graphene can hear your brain whisper
A newly developed graphene-based implant can record electrical activity in the brain at extremely low frequencies and over large areas, unlocking the wealth of information found below 0.1 Hz. This technology, which will be showcased in the Graphene Pavilion at Mobile World Congress in Barcelona (25-28 February 2019) was developed by Graphene Flagship partners at the Barcelona Microelectronics Institute (IMB-CNM, CSIC), the Catalan Institute of Nanoscience and Nanotechnology (ICN2), and ICFO. (2019-01-24)

New insights into why we crave fatty foods when dieting
Researchers from The University of Texas Medical Branch at Galveston have identified new brain circuits that may act as a brake on binge eating and junk food craving. In rats who had spent a month eating a low-fat diet, researchers successfully inhibited the fatty food seeking behaviors. (2019-01-24)

With less sleep, tau release in the brain goes up
The sleep-wake cycle affects the levels of a protein in our brain called tau, a new study in animals and humans shows. (2019-01-24)

New tumor test could guide personalized treatment for children with cancer
Scientists at the University of British Columbia and BC Children's Hospital are the first in Canada to use a new test for pediatric tumor analysis that may one day guide personalized treatments for children with cancer. (2019-01-23)

Even in young adults, blood pressure above normal may be linked to brain shrinkage
For people in their 20s and 30s, having blood pressure above normal but below the level considered to be high blood pressure, may be linked to loss of brain volume, according to a study published in the January 23, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology. (2019-01-23)

Should we rename low-risk cancers?
Should we rename low-risk ('indolent') cancers in a bid to reduce anxiety and harm from unnecessary investigation and treatment? Experts debate the issue in The BMJ today. (2019-01-23)

Tasmanian devil cancer unlikely to cause extinction, say experts
Transmissible cancer which has devastated Tasmanian devil populations is unlikely to cause extinction, according to latest research. (2019-01-23)

Researchers create road map of care for children with severe head trauma
PEGASUS is the first comprehensive care model for children with head trauma, said lead researcher Monica Vavilala, director of Harborview's Injury Prevention and Research Center in Seattle. (2019-01-23)

Fralin Biomedical Research Institute scientists link concussions to epilepsy development
Experiments by Fralin Biomedical Research Institute scientists show a strong relationship between changes in astrocytes after mild traumatic brain injury and the eventual occurrence of a seizure. (2019-01-22)

How concussions may lead to epilepsy
Researchers have identified a cellular response to repeated concussions that may contribute to seizures in mice like those observed following traumatic brain injury in humans. The study, published in JNeurosci, establishes a new animal model that could help improve our understanding of post-traumatic epilepsy. (2019-01-21)

How our brains distinguish between self-touch and touch by others
Our brains seem to reduce sensory perception from an area of our skin when we touch it ourselves, according to a new study from Linköping University, Sweden, published in the journal Proceedings of the National Academy of Sciences, PNAS. The finding increases our understanding of how the brain distinguishes between being touched by another person and self-touch. (2019-01-21)

Gene changes may predict breast cancer relapse, study suggests
Scientists at the University of Edinburgh have identified genetic changes that may predict the likelihood of breast cancer relapse in women taking a common type of hormone therapy. (2019-01-21)

Nerve growth factor: Early studies and recent clinical trials
NGF is the first discovered member of a family of neurotrophic factors, collectively indicated as neurotrophins, (which include brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin 4/5). NGF was discovered for its action on the survival and differentiation of selected populations of peripheral neurons. (2019-01-18)

Findings on eye-signal blending re-examines Nobel-winning research
Knowing precisely where the signals meet and the brain processes them is vital to treating amblyopia, or reduced vision in one eye because the brain and eye aren't working together properly. (2019-01-17)

The cerebellum's hidden roles in social and reward-driven behavior
The cerebellum may regulate sociability and reward-driven behavior by controlling the release of dopamine, according to a new study. (2019-01-17)

Regulation and potential drug targets of tumor-associated Tregs
Multiple studies indicate that tumour-associated regulatory T cells (Tregs) play a detrimental role in the antitumour immune responses. Decreasing the numbers of Tregs or inhibiting the Treg function will contribute to the antitumour effects. However, it is unclear which molecules of Tregs are suitable targets for tumour immunotherapy with minimal toxic side effects. Here researchers review the regulatory mechanisms of Tregs within the tumour microenvironment, and address potential drug targets on Tregs for immunotherapy. (2019-01-15)

Researchers discover common markers of tumor hypoxia across 19 cancer types
Unlike healthy tissues, tumors thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despite being a well-known cause of therapy resistance and metastasis, the impact of low oxygen, known as hypoxia, on tumor cells is poorly understood. As reported today in Nature Genetics, researchers have discovered molecular hallmarks of hypoxia in the first-ever pan-cancer analysis of low oxygen in human tumors, with a special focus on prostate cancer. (2019-01-14)

Teen brain volume changes with small amount of cannabis use, study finds
At a time when several states are moving to legalize recreational use of marijuana, new research shows that concerns about the drug's impact on teens may be warranted. The study shows that even a small amount of cannabis use by teenagers is linked to differences in their brains. (2019-01-14)

Parasites from patients with cerebral malaria stick preferentially in their brains
A team at LSTM with their collaborators in Malawi and Denmark have provided, for the first time, evidence which links the ability of red blood cells infected with the malaria parasite to bind to the cells lining the blood vessels of the brain, with the clinical syndrome cerebral malaria. (2019-01-11)

Early development of memory for space and time
By observing how newborn rats first navigate and begin to remember the environments they are born into, researchers have gained new insight into how brains develop the ability to turn experiences into memory. (2019-01-10)

Study: Excessive body fat around the middle linked to smaller brain size
Carrying extra body fat, especially around the middle, may be linked to brain shrinkage, according to a study published in the Jan. 9, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology. For the study, researchers determined obesity by measuring body mass index (BMI) and waist-to-hip ratio in study participants and found those with higher ratios of both measures had the lowest brain volume. (2019-01-09)

NUS scientists harness machine learning to uncover new insights into the human brain
An inter-disciplinary research team led by the National University of Singapore has successfully employed machine learning to uncover new insights into the cellular architecture of the human brain. This approach could potentially be used to assess treatment of neurological disorders, and to develop new therapies. (2019-01-09)

New insights into a rare type of cancer open novel avenues of study
Undifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteristics of clinical importance -- a new study at Karolinska Institutet in Sweden reveals. The results, published in the journal Clinical Cancer Research, also show that the survival rate of patients with a certain type of tumour is better than predicted. (2019-01-08)

Melanoma: dabrafenib and trametinib have added benefit
This combination showed advantages in survival and recurrence. An added benefit was not proven for another combination used in advanced disease. (2019-01-08)

Technique boosts omega 3 fatty acid levels in brain 100 fold
Researchers from the University of Illinois at Chicago report that adding a lysophospholipid form of EPA (LPC-EPA) to the diet can increase levels of EPA in the brain 100-fold in mice. (2019-01-08)

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