Current Breast Cancer News and Events

Current Breast Cancer News and Events, Breast Cancer News Articles.
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'Good bacteria' in breast milk changes over time
The cocktail of beneficial bacteria passed from mother to infant through breast milk changes significantly over time and could act like a daily booster shot for infant immunity and metabolism. The research, conducted by scientists from Montreal and Guatemala and published in Frontiers in Microbiology, has important implications for infant development and health. (2021-02-23)

Markey's ACTION program develops cancer education curriculum for Appalachian schools
After conducting a study to assess the need for cancer education materials in Appalachian Kentucky, members of the University of Kentucky Markey Cancer Center's Appalachian Career Training in Oncology (ACTION) program worked with faculty from the UK College of Education to create a three-part cancer education curriculum for middle and high school teachers in the region. (2021-02-23)

The unveiling of a novel mechanism of resistance to immunotherapy targeting HER2
VHIO investigators report how HER2 breast cancer cells adopt a strategy to resist clearance by redirected lymphocytes. Findings evidence that the disruption of interferon-gamma signaling confers resistance to these immunotherapies and promotes disease progression. Reported in Nature Communications, these results could help to potentiate future immune-based strategies and more precisely identify those patients who would be most likely to benefit from them. (2021-02-23)

Study shows new treatment pathway to prevent and treat endometrial cancer recurrence
In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. (2021-02-23)

Cancer cell vulnerability points to potential treatment path for aggressive disease
A new study in Nature Communications describes the discovery of a unique dependence of cancer cells on a particular protein, which could lead to desperately needed treatment for hard-to-treat cancers. (2021-02-22)

Scientists model a peculiar type of breast cancer
Scientists led by EPFL have developed a breakthrough in vivo model for invasive lobular carcinoma, a serious yet understudied type of breast cancer. The work will open up previously inaccessible study of the tumor's biology and help discover new therapies. (2021-02-22)

NYUAD researchers develop high throughput paper-based arrays of 3D tumor models
By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms. With the new paper-based technology, the formed tumor models can be safely cryopreserved and stored for prolonged periods for on-demand drug testing use. (2021-02-22)

Investment needed to bring down pancreatic cancer death rates in Europe
Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years. The latest predictions for cancer deaths in the EU and UK for 2021, published in the leading cancer journal Annals of Oncology, show that pancreatic death rates are predicted to remain approximately stable for men, but continue to rise in women in most EU countries. (2021-02-21)

Race, income, education affect access to 3D mammography
Women of minority races and ethnicities and with less education and income have had relatively lower access to 3D mammography, a technology that can improve breast cancer detection and decrease false alarms, according to new research. (2021-02-19)

Turbocharging the killing power of immune cells against cancer
Creating ''super soldiers'' of specific white blood cells to boost an anti-tumour response has been shown in a series of elegant experiments by Princess Margaret researchers. (2021-02-19)

Mayo Clinic researchers develop test to measure effect of breast cancer gene variants
Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were published today in a study in the American Journal of Human Genetics. (2021-02-19)

Addressing the biological causes of racial disparities in prostate cancer
A new review published in Cancer Reports examines the biological differences in the development of prostate cancer across ethnicities. (2021-02-18)

Physical conditions linked to psychological distress in patients with cancer
Among patients with cancer, having additional physical comorbidities was linked with a higher risk of experiencing psychological distress. The finding comes from a Psycho-Oncology analysis of 2017 data from the National Health Survey of Spain. (2021-02-18)

Perception critical to women's breast reconstruction decision making
Women who undergo surgical treatment for breast cancer often also have reconstructive surgery but new research from QUT in Australia reveals many feel left out of the decision making process. Approximately one in every three women surveyed stated their surgeon had more input than they did. (2021-02-18)

Phase I clinical trial shows promise of adipose-derived stem cells in treating lymphedema
Results of a phase I clinical trial released in STEM CELLS Translational Medicine shows there is a strong possibility that stem cells may alleviate lymphedema, a chronic debilitating condition affecting up to one in three women treated for breast cancer. (2021-02-17)

Scientists able to see how potential cancer treatment reacts in single cell
Using a 185 metre beamline at the Diamond synchrotron, researchers could see how Osmium, a rare precious metal that could be used for cancer treatments, reacts in a single human lung cancer cell. This is a major step forward in discovering new anti-cancer drugs for researchers at the University of Warwick. (2021-02-17)

Toward a disease-sniffing device that rivals a dog's nose
A new system can detect the chemical and microbial content of an air sample with even greater sensitivity than a dog's nose. Researchers at MIT and elsewhere coupled this to a machine-learning process that can identify the distinctive characteristics of the disease-bearing samples. (2021-02-17)

Advances in x-ray imaging can help patients with breast cancer
A new approach to X-ray imaging can help surgeons performing breast cancer tumour removal surgery, giving 2.5 times better detection of diseased tissue around the edge of the tumour than with standard imaging. (2021-02-17)

Proton therapy induces biologic response to attack treatment-resistant cancers
Mayo Clinic researchers have developed a novel proton therapy technique to more specifically target cancer cells that resist other forms of treatment. The technique is called LEAP, an acronym for 'biologically enhanced particle therapy.' The findings are published today in Cancer Research, the journal of the American Association for Cancer Research. (2021-02-17)

Study demonstrates the reasons to screen children with cancer for inherited cancer genes
Experts at MSK Kids, the pediatric oncology program at MSK, have found that inherited cancer genes are more common than expected in children with cancer. (2021-02-16)

Unexpected findings on weight loss and breast cancer from international study in JNCCN
New research in the February 2021 issue of JNCCN--Journal of the National Comprehensive Cancer Network examined body mass index (BMI) data for people with HER2-positive early breast cancer, and found a 5% weight loss in patients over two years in was associated with worse outcomes. Weight gain over the same time period did not affect survival rates. (2021-02-16)

Fixer-upper: Understanding the DNA repair toolkit to chart cancer evolution
DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers. A group of scientists from China have conducted an extensive investigation into the relationship of DNA repair pathways with cancer evolution. Their review, been published in Cancer Biology & Medicine, also shed light on the potential treatment applications of these mechanisms. (2021-02-16)

Molecular imaging determines effectiveness of novel metastatic breast cancer treatment
Molecular imaging can successfully predict response to a novel treatment for ER-positive, HER2-negative metastatic breast cancer patients who are resistant to hormonal therapy. According to research published in the February issue of The Journal of Nuclear Medicine, positron emission tomography (PET) imaging using an imaging agent called 18F-fluoroestradiol can help to determine which patients could benefit from treatments that could spare them from unnecessary chemotherapy. (2021-02-16)

Suppressive immune cells' metabolic vulnerability may be targeted for cancer immunotherapy
A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors. (2021-02-16)

Oncotarget: AKT isoforms have discrete expression in triple negative breast cancers
Oncotarget recently published ''AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity'' which reported that the authors investigated the expression and net effect of the individual isoforms in triple negative breast cancers and response to cisplatin treatment using cellular, mice models and clinical samples. (2021-02-15)

To improve immunotherapy, researchers look to shift immune cells' access to sugar
New research from Memorial Sloan Kettering scientists suggests that a way to improve immunotherapy is by altering immune cells' access to sugar. (2021-02-15)

Exercise now proven to have mental health benefits for prostate cancer
New Edith Cowan University (ECU) research has found that exercise not only has physical benefits for men with prostate cancer, it also helps reduce symptoms of depression and anxiety. (2021-02-15)

Going the distance--insights into how cancer cells spread
In a study published in Nature Communications, cancer researchers at Kanazawa University identify mechanisms by which malignant tumor cells extend their toxicity to distinct cell types and in turn help them spread. (2021-02-12)

Liquid biopsy for colorectal cancer could guide therapy for tumors
A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor. Such a biopsy can detect lingering disease and could serve as a guide for deciding whether a patient should undergo further treatments due to some tumor cells evading an initial attempt to eradicate the cancer. (2021-02-12)

Study identifies never-before-seen dual function in enzyme critical for cancer growth
In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists aim to identify ways to keep cancer cells from using DNA break repair pathways. New findings demonstrate a previously-unknown capability for polymerase theta (pol theta) - a key enzyme in this repair function - that shows promise as a new avenue for treatment development. (2021-02-11)

SRC-3 is a novel regulator of human immune T regulatory cells
SRC-3, a prognostic marker for aggressive human breast and other cancers, also regulates human immune T regulatory cells (Tregs), which are involved in fighting cancer. (2021-02-11)

Oncotarget: Melatonin increases overall survival of prostate cancer patients
'The results of the use of melatonin drugs in palliative treatment of patients with end-stage prostate cancer are shown' (2021-02-10)

How cells recycle the machinery that drives their motility?
Research groups at University of Helsinki and Institut Jacques Monod, Paris, discovered a new molecular mechanism that promotes cell migration. The discovery sheds light on the mechanisms that drive uncontrolled movement of cancer cells, and also revises the 'text book view' of cell migration. (2021-02-09)

Breast cancer death rates stop declining in younger women
Breast cancer death rates have stopped declining for women in the U.S. younger than age 40, ending a trend that existed from 1987 to 2010, according to a new study. Researchers expressed hope that the findings would raise awareness of breast cancer in younger women and spur research into the causes behind the change. (2021-02-09)

New study discovers possible early detection method for elusive ovarian cancer
A study led by researchers at the University of Minnesota Medical School found a way to detect the presence of ovarian cancer in patients using Pap test samples, normally used to detect cervical cancer. (2021-02-09)

Drug is promising against pancreatic and breast cancers
The drug is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also effective against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast cancer that carries a poor prognosis. Clinical trials are set to begin in 2021. (2021-02-09)

Study links exposure to nighttime artificial lights with elevated thyroid cancer risk
People living in regions with high levels of outdoor artificial light at night may face a higher risk of developing thyroid cancer. The finding comes from a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. (2021-02-08)

Halt cell recycling to treat cancer
Targeting and changing autophagy, otherwise known as cell recycling, has been linked to helping control or diminish certain cancers. Now, University of Cincinnati researchers have shown that completely halting this process in a very aggressive form of breast cancer may improve outcomes for patients one day. (2021-02-08)

Ophiura from Russky Island might make photodynamic therapy more affordable
An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers. Researchers from the School of Biomedicine of Far Eastern Federal University (FEFU) and the University of Geneva reported the findings in Marine Drugs. (2021-02-08)

Female breast cancer surpasses lung as the most commonly diagnosed cancer worldwide
Cancer ranks as a leading cause of death in every country in the world, and, for the first time, female breast cancer is the most commonly diagnosed cancer, overtaking lung cancer, according to a collaborative report, Global Cancer Statistics 2020, from the American Cancer Society (ACS) and the International Agency for Research on Cancer (IARC). (2021-02-04)

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