Current Breast Cancer News and Events

Current Breast Cancer News and Events, Breast Cancer News Articles.
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Gene donors at high risk for cancer received feedback
Researchers at the Estonian Genome Center at the University of Tartu studied how people at high risk for breast, ovarian or prostate cancer responses to the feedback of genetic findings. Gene donors who chose to receive results appreciated being contacted and considered the information provided to be valuable. Authors find that knowing more about people's genetic traits will significantly expand the chances of early detection of breast-, ovarian- and prostate cancer in the future. (2020-11-25)

Social needs linked to low health-related quality of life among African American cancer survivors
Social needs--such as food and economic insecurity, poor housing and neighborhood conditions, and lack of access to transportation--were common in a group of African American cancer survivors in Detroit, and they were associated with lower health-related quality of life (HRQOL). The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). (2020-11-23)

NHS Breast Screening Programme still effective in reducing deaths in England
An England-wide study led by Queen Mary University of London has shown that, despite major improvements in diagnostic techniques and treatments, mammography screening continues to play an important role in lowering the risk of dying from breast cancer (2020-11-22)

Breast cancer discovery could help stop disease's deadly spread
Researchers have identified a gene responsible for the spread of triple-negative breast cancer to other parts of the body and developed a potential way to stop it. (2020-11-20)

Food, housing insecurities may delay breast cancer diagnosis
Women who experience food or housing insecurity may be at risk for undiagnosed breast cancer due to lapses in follow-up appointments, according to research being presented at the annual meeting of the Radiological Society of North America (RSNA). (2020-11-19)

Frozen eggs and ovarian tissue helped women conceive children after breast cancer
Women with breast cancer whose eggs or ovarian tissue were frozen had more children after their diagnosis than women who did not undergo fertility preservation using those methods before start of cancer treatment. That is according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal JAMA Oncology. According to the researchers, the result highlights the importance of reproductive counseling and fertility preservation for women who are diagnosed with cancer at a young age. (2020-11-19)

Scientists discover roles for a cellular motor in cancer
Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers. The study was published in print today in the journal Molecular Cell. (2020-11-19)

A more sensitive way to detect circulating tumor cells
Breast cancer is the most frequently diagnosed cancer in women, and metastasis from the breast to other areas of the body is the leading cause of death in these patients. Detecting circulating tumor cells (CTCs) in the bloodstream could help doctors find and treat metastases at an earlier stage, increasing chances of survival. Now, researchers reporting in ACS Sensors have developed a method that could more sensitively detect CTCs within the complex environment of blood. (2020-11-18)

A DNA-based nanogel for targeted chemotherapy
Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells. Now, researchers reporting in ACS' Nano Letters have designed DNA-based nanogels that only break down and release their chemotherapeutic contents within cancer cells, minimizing the impacts on normal ones and potentially eliminating painful and uncomfortable side effects. (2020-11-18)

Proteogenomics enhances the identification of therapeutic vulnerabilities in breast cancer
Applying powerful proteogenomics approaches to breast cancer, researchers propose more precise diagnostics, identify new tumor susceptibilities for translation into treatments and implicate new mechanisms involved in breast cancer treatment resistance. (2020-11-18)

Patients strongly favor banning bacon in hospitals, according to new survey
Most hospitalized patients favor eliminating processed meats--including bacon, deli meat, and sausage--from hospital menus to reduce cancer risk, according to a new survey published in the Journal of Hospital Management and Health Policy. (2020-11-18)

Existing antidepressant helps to inhibit growth of cancer cells in lab animals
New research has shown that the antidepressant sertraline helps to inhibit the growth of cancer cells. The substance acts on a metabolic addiction that allows different types of cancer to grow. This is shown by a study on cell cultures and lab animals by researchers at KU Leuven. (2020-11-17)

Certain CBD oils no better than pure CBD at inhibiting certain cancer cell lines
Cannabidiol (CBD) oils are equally or less effective at inhibiting the growth of certain cancer cells compared to pure CBD, according to Penn State College of Medicine researchers. The results of their recent study indicate that future research into the clinical applications of cannabinoids should include an analysis of whether the pure cannabinoid compound or intact plant material is more effective at achieving the therapeutic effect. (2020-11-17)

Screening younger women for hereditary cancers may be cost effective
Population-wide screening for genetic variants linked to hereditary breast and ovarian cancer may be cost effective in women between the ages of 20 and 35, according to a study published in JAMA Network Open. (2020-11-16)

Cancer metastasis: From problem to opportunity
When cancer metastasizes, it often ends up in the lungs, where the new tumors unleash a cascade of chemical cues that thwart the body's immune response. A team of researchers from the Wyss Institute has created a new approach that attacks metastasis itself by using red blood cells as couriers to deliver nanoparticles filled with immune-cell-attracting chemicals. This approach halted lung tumor growth in mice with metastatic breast cancer and protected the animals against future cancer recurrences.  (2020-11-16)

Cancer deaths resulted in more than 4 million potential years of life lost in 2017
Deaths from cancer accounted for more than 4 million potential years of life lost in 2017, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. (2020-11-13)

Singapore scientists identify potential new biomarker to better personalize cancer therapy
Testing for mutations in RNF43, a protein that affects key cancer cell-growth pathway Wnt, gives clinicians actionable insights to tailor treatments better. (2020-11-13)

Sussex research points to new effective breast cancer treatment
An international five-year study led by scientists at the University of Sussex has provided strong evidence for an effective new target for breast cancer treatment. The study, The structure-function relationship of oncogenic LMTK3 being published in Science Advances, involved researchers from seven institutions across three countries including the UKs Diamond Light Source. It suggests LMTK3 inhibitors could be effectively used for treatment of breast cancer, and potentially other types of cancer such as lung, stomach, thyroid and bladder cancer patients (2020-11-13)

Rare angiosarcoma tumors respond well to immunotherapy combination
Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute's (NCI) Division of Cancer Diagnosis and Treatment (DCTD), part of the National Institutes of Health, have shown that the immunotherapy combination of ipilimumab and nivolumab shrinks rare angiosarcoma tumors in 25 percent of all patients, with some having an even stronger response to the drug combination. (2020-11-13)

State-level lung cancer screening rates not aligned with lung cancer burden in the US
A new study reports that state-level lung cancer screening rates were not aligned with lung cancer burden. (2020-11-12)

Brain metastases cause severe brain damage that can be inhibited by treatment
By using a specific treatment to override this activation, the researchers were able to return cerebrovascular flow to healthy levels. This improvement in blood flow around the metastases can limit the neurological deterioration associated with the progression of this disease and improve the otherwise poor life expectancy of these patients. (2020-11-12)

Researchers show safer, more targeted way to deliver CRISPR gene therapy
Biomedical researchers have come up with a novel way to use a beam of light to deliver CRISPR gene therapy molecules targeting illnesses. (2020-11-11)

Penn researchers present findings on cardiac risks for cancer patients
Physician-researchers from the Perelman School of Medicine at the University of Pennsylvania will present findings about cardiac care for cancer patients and survivors at the American Heart Association's Scientific Sessions 2020. (2020-11-10)

Tomosynthesis with synthetic mammography improves breast cancer detection
Digital breast tomosynthesis (DBT), in combination with synthetic mammography, improves cancer detection over digital mammography alone, according to a new study. The study results add further support to the use of DBT in population-based breast cancer screening programs. (2020-11-10)

Oncotarget: IGF2 expression in breast cancer tumors and in breast cancer cells
The Oncotarget authors propose that methylation of DVDMR represents a novel epigenetic biomarker that determines the levels of IGF2 protein expression in breast cancer. (2020-11-10)

As cancer has evolved, it is time for cancer research to do the same
Marking Lung Cancer Awareness month, a new study investigates the extent to which human-based, non-animal approaches are supplanting animal models in cancer research - comparing number of publications, funding, and publications associated with clinical trials between xenograft models and human organoids. The analysis reveals limited support for human biology-based methods and the authors recommend encouraging efforts to reduce reliance on animal testing in order to accelerate discovery and development of new, effective and affordable medicines. (2020-11-10)

New analysis finds lung cancer screening reduces rates of lung cancer-specific death
Low-dose CT screening methods may prevent one death per 250 at-risk adults screened, according to a meta-analysis of eight randomized controlled clinical trials of lung cancer screening. Researchers at the University of Georgia analyzed the health outcomes of 90,275 patients, comparing those who were screened versus those who received usual medical care or chest x-rays. (2020-11-10)

New cancer drugs saved over 1.2 million people in the US over 16 years, new study shows
More than 1.2 million people in the US prevented facing death following a cancer diagnosis, between the year 2000 and 2016, thanks to ever improving treatment options -- a large new national study shows. (2020-11-09)

New research supports clinical utility of CTC count for metastatic breast cancer
Menarini Silicon Biosystems, the pioneer of liquid biopsy technology, today announced the publication of a research study providing support for the reliability of using circulating tumor cell (CTC) count to guide frontline therapy choice for patients with estrogen receptor-positive (ER+), HER2-negative (HER2) metastatic breast cancer. Published in the November issue of JAMA Oncology, this is the first study to support clinical utility of CTC count in a randomized clinical trial. (2020-11-09)

Anti-depressant repurposed to treat childhood cancer
A new study has found that a commonly prescribed anti-depressant may halt growth of a type of cancer known as childhood sarcoma, at least in mice and laboratory cell experiments. The findings, from researchers at Karolinska Institutet in Sweden and MD Anderson Cancer Centre in Texas, ignite hope of novel treatment strategies against this disease. The study is published in the journal Cancer Research. (2020-11-06)

Medicaid expansion linked to lower mortality rates for three major types of cancer
In states that have expanded Medicaid availability as part of the Affordable Care Act (ACA), mortality rates for three major forms of cancer are significantly lower than in states that have not expanded their Medicaid, a new study by researchers at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Harvard University shows (2020-11-05)

Large-scale cancer proteomics study profiles protein changes in response to drug treatments
Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies. (2020-11-05)

Precision chemo-immunotherapy for pancreatic cancer?
Pancreatic cancer is highly lethal: according to the National Cancer Institute, only about 10 percent of patients remain alive five years after diagnosis. Now, a preclinical study from the lab of Marsha Moses, PhD at Boston Children's Hospital, reports marked and lasting tumor regression in a mouse model, using a highly selective, potent, engineered antibody-drug combination. (2020-11-05)

AI tool improves breast cancer detection on mammography
Artificial intelligence (AI) can enhance the performance of radiologists in reading breast cancer screening mammograms, according to a new study. (2020-11-04)

New insights on a common protein could lead to novel cancer treatments
A new University of Colorado Boulder-led study sheds light on a protein key to controlling how cells grow, proliferate and function and long implicated in tumor development. (2020-11-04)

Every month delayed in cancer treatment can raise risk of death by around 10%
People whose treatment for cancer is delayed by even one month have in many cases a 6 to 13% higher risk of dying - a risk that keeps rising the longer their treatment does not begin - suggests research published online in The BMJ. (2020-11-04)

Oncotarget: Predictive biomarkers in Trop-2-expressing triple-negative breast cancer
SG could provide better clinical benefit than irinotecan in patients with HRR-proficient tumors expressing high levels of Trop-2, as well as to patients with HRR-deficient tumors expressing low/moderate levels of Trop-2. (2020-11-03)

Oncotarget: Heterogeneity of CEACAM5 in breast cancer
Oncotarget recently published ''Heterogeneity of CEACAM5 in breast cancer'' which reported that Here, we examined a repository of 110 cryopreserved primary breast carcinomas by immunohistochemistry to assess the distribution of CEACAM5 in tumor subtypes. (2020-11-03)

New analysis method can lead to better cancer drugs
While proteins on the surface of cells are the targets for most drugs, refined methods are needed to analyse how these membrane proteins are organised. Researchers at Karolinska Institutet have developed a new DNA-based analytical method that could contribute to the development of future drugs for breast and other cancers. The study is published in Nature Nanotechnology. (2020-11-02)

Nerves keep pancreatic cancer cells from starving
Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online November 2 in Cell. (2020-11-02)

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