Current Breast Cancer News and Events | Page 25

Current Breast Cancer News and Events, Breast Cancer News Articles.
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AJR publishes gender affirmation surgery primer for radiologists
Since gender incongruence is now categorized as a sexual health condition, an ahead-of-print article published in the December issue of the American Journal of Roentgenology (AJR) contends that all subspecialties must be prepared to identify radiologic correlates and distinguish key postoperative variations in the three major categories of gender affirmation surgery: genital reconstruction, body contouring, and maxillofacial contouring. (2019-08-19)

Targeting cell division in pancreatic cancer
Study provides new evidence of synergistic effects of drugs that inhibit cell division and support for further clinical trials. (2019-08-19)

MDM2 counteracts resistance to CDK4/6 inhibitors for melanoma therapy
A study from Vanderbilt-Ingram Cancer Center and the Department of Veterans Affairs led by Anna Vilgelm, MD, Ph.D., and Ann Richmond, Ph.D., has identified a possible second-line treatment for melanoma patients. (2019-08-15)

New contrast agent could make MRIs safer
Researchers at Massachusetts General Hospital have taken a key step forward in developing a new, possibly safer contrast agent for use in MRI exams. (2019-08-15)

Discovery of how cells override genetic changes
A discovery by scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) could lead researchers to a more effective way to treat pancreatic cancer. Their findings were published today in Developmental Cell. (2019-08-15)

More cancer cases among women with sleep apnea
Women with severe sleep apnea appear to be at an elevated risk of getting cancer, a study shows. No causal relationship is demonstrated, but the link between nocturnal hypoxia in women and higher cancer risk is still clear. (2019-08-15)

Nanocapsule reaches cancer that has spread to central nervous system in mice
Researchers developed a drug delivery system that can break through the blood-brain barrier in mice. (2019-08-14)

Lavender oil may contribute to abnormal breast growth in young girls
Abnormal breast growth in young girls is linked to lavender oil exposure, according to a recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2019-08-14)

New drug shows encouraging survival in pancreatic cancer
A phase 1 clinical trial testing a new drug in pancreatic cancer had promising initial results, report researchers from the University of Michigan Rogel Cancer Center. The trial looked at AZD1775, an inhibitor designed to block an enzyme called Wee1, which plays a role in DNA damage repair. (2019-08-14)

New study helps to understand human defence mechanisms and spread of cancer
With the help of new technology, the researchers of the University of Turku in Finland have gained more detailed information on the diversity of the human lymphatic system than before. The research results can help to understand the human defence mechanisms on the molecular level even better than before. Several cancers, such as breast cancer and head and neck cancers, spread primarily via the lymphatic system. (2019-08-13)

Inherited pancreatic cancer risk mutation identified
The discovery of the previously unknown mutation, reported in Nature Genetics by investigators from Dana-Farber/Brigham and Women's Cancer Center, could lead to routine testing of individuals with a strong family history of pancreatic cancer to determine if they carry the mutation, occurring in the gene known as RABL3. (2019-08-12)

Key to targeting the spread of pancreatic cancer
Targeting the tissue around pancreatic cancer cells may be the key to stopping their spread and improving chemotherapy outcomes. (2019-08-12)

Aspirin may help some breast cancer survivors, but changes in DNA may mean harm for others
Previous studies have shown that while some women who use aspirin and are later diagnosed with breast cancer may live longer, a portion of aspirin users with breast cancer appeared to have a higher risk of mortality following breast cancer. According to a new study from the University of North Carolina at Chapel Hill Gillings School of Global Public Health, the reason for this reverse effect could be explained by DNA methylation of genes in breast cancer tumors or peripheral blood. (2019-08-12)

Managing ovarian cancer risk in women with BRCA1/2 genetic variants
A new review to help physicians manage the risk of ovarian cancer in women who carry the BRCA1/2 gene mutations is published in CMAJ. (2019-08-12)

Aspirin may interact with cells' DNA modifications to alter breast cancer outcomes
New findings suggest that women with specific DNA characteristics in certain areas of the genome may live longer if they take aspirin before they are diagnosed with breast cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings point to the need for studies on the potential of aspirin to prevent or treat breast cancer in some individuals. (2019-08-12)

Manipulating dose, timing of two therapies reduces relapse in mouse models of breast cancer
Changing the standard dose and timing of two therapies greatly cut tumor relapse and reduced side effects in mouse models of kinase mutated breast cancer and lung cancer, UT Southwestern Simmons Cancer Center researchers have found. (2019-08-09)

Artificial intelligence could yield more accurate breast cancer diagnoses
UCLA researchers have developed an artificial intelligence system that could help pathologists read biopsies more accurately and to better detect and diagnose breast cancer. (2019-08-09)

Balance of 'stop' and 'go' signaling could be key to cancer immunotherapy response
A crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by cancer cells to put the brakes on the immune system. (2019-08-08)

Electromagnetic fields may hinder spread of breast cancer cells
Electromagnetic fields might help prevent some breast cancers from spreading to other parts of the body, new research has found. The study showed that low intensity electromagnetic fields hindered the mobility of specific breast cancer cells by preventing the formation of long, thin extensions at the edge of a migrating cancer cell. (2019-08-08)

Having a parent, sibling, or child with blood cancer increases one's own risk
New data suggest that people who have a parent, sibling, or child with blood cancer have a higher likelihood of being diagnosed with the disease. (2019-08-08)

Personalized assay surpasses limits for detecting tumor DNA in breast cancer patients
Scientists have developed a personalized platform tailored to patients' specific cancer mutations named TARDIS, which was able to accurately detect circulating tumor DNA (ctDNA) and signs of residual disease in 33 women with breast cancer. (2019-08-07)

New 'liquid biopsy' blood test improves breast cancer diagnostics
A new type of blood test for breast cancer could help avoid thousands of unnecessary surgeries and otherwise precisely monitor disease progression, according to a study led by the Translational Genomics Research Institute (TGen) and Mayo Clinic in Arizona. TGen is an affiliate of City of Hope, which along with The Cancer Research UK Cambridge Institute at Cambridge University and the Biodesign Institute at Arizona State University (ASU) also contributed to this study. (2019-08-07)

Cancer in the oldest old: The fastest growing age group in the US
A new report looks at cancer in adults 85 and older and finds incidence and mortality trends are generally similar to those in people 65 to 84, but screening is unexpectedly high and survival is poorer. (2019-08-07)

Nordic walking can provide multiple benefits for patients with breast cancer
An analysis of published studies found that Nordic walking -- a low impact aerobic activity consisting in walking with poles -- can benefit patients with breast cancer by having a positive impact on swelling, physical fitness, disability, and quality of life. (2019-08-07)

Substituting poultry for red meat may reduce breast cancer risk
Results from a new study suggest that red meat consumption may increase the risk of breast cancer, whereas poultry consumption may be protective against breast cancer risk. The findings are published in the International Journal of Cancer. (2019-08-07)

What can you do with two omes that you can't do with one?
In an issue on multiomics, researchers report new approaches to study the microbiome, cancer and other diseases by combining proteomics, genomics, transcriptomics and other high-throughput ways to collect data. (2019-08-06)

AI reveals new breast cancer types that respond differently to treatment
Scientists have used artificial intelligence to recognize patterns in breast cancer -- and uncovered five new types of the disease each matched to different personalized treatments. (2019-08-02)

Researchers from the IDIBELL and the University of Barcelona describe a new treatment that could cope with 2 bone diseases
Researchers have found a possible treatment for 2 bone diseases that have actually no cure. (2019-08-02)

Despite treatment, elderly cancer patients have worse outcomes if HIV-positive
Elderly cancer patients who are HIV-positive have worse outcomes compared to cancer patients in the same age range who do not have HIV. A new study in JAMA Oncology takes a closer look at the disparity, factoring in whether or not cancer treatment had an impact on outcomes among this patient population. (2019-08-01)

New 'don't eat me' signal may provide basis for cancer therapies, Stanford researchers say
Researchers at the Stanford University School of Medicine have discovered a new signal that cancers seem to use to evade detection and destruction by the immune system. The scientists have shown that blocking this signal in mice implanted with human cancers allows immune cells to attack the cancers. (2019-07-31)

AI improves efficiency and accuracy of digital breast tomosynthesis
Artificial intelligence (AI) helps improve the efficiency and accuracy of an advanced imaging technology used to screen for breast cancer, according to a new study. (2019-07-31)

p53 mutations in 10,000 cancer patients shed new light on gene's function
One of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppressor. Researchers at Baylor College of Medicine have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene. Their findings shed light on how the gene becomes mutated and how those mutations can help predict clinical outlook. (2019-07-30)

New drug providing hope for babies with aggressive Acute Lymphoblastic Leukaemia
A breakthrough new drug is providing hope to tiny babies at risk of dying from an aggressive form of Acute Lymphoblastic Leukaemia and could help all cancer patients. (2019-07-27)

Antibiotics can inhibit skin lymphoma
New research from the LEO Foundation Skin Immunology Research Center at the University of Copenhagen shows, surprisingly, that antibiotics inhibit cancer in the skin in patients with rare type of lymphoma. (2019-07-25)

Inherited BRCA2 mutations linked to increased risk of childhood lymphoma
A report from St. Jude Children's Research Hospital links inherited mutations in the BRCA2 gene with an increased risk of developing non-Hodgkin lymphoma in children and adolescents. The work appears as an advance online publication today in JAMA Oncology. (2019-07-25)

Clinical trial identifies new breast cancer drug as a potential therapy for glioblastoma
Ivy Brain Tumor Center at the Barrow Neurological Institute, has released the results of its recent Phase 0 clinical trial of the breast cancer drug ribociclib (Kisqali®) for the treatment of recurrent glioblastoma. The agent, recently approved by the FDA for advanced breast cancer, is part of a newly-discovered class of targeted therapy that undermines cancer cell division and could form the backbone of a new drug cocktail for patients with malignant brain tumors like glioblastoma. (2019-07-25)

Pilot study of 5-hour molecular test accurately distinguishes malignant and benign breast tumors
A team led by Johns Hopkins Kimmel Cancer Center investigators reports that a new laboratory test they developed to identify chemical changes to a group of cancer-related genes can accurately detect which breast tumors are cancerous or benign, and do it in far less time than gold-standard tests on biopsied breast tissue. (2019-07-24)

Researchers find evidence a cancer drug may be extended to many more patients
Drugs currently used to treat less than 10% of breast cancer patients could have broader effectiveness in treating all cancers, including ovarian and prostate cancers. (2019-07-24)

Outcompeting cancer
Suppressing the capacity of tumors to destroy the healthy tissue that surrounds them is essential for fighting cancer-induced morbidity and mortality. Now, a new study in human-derived tumors reveals a potential way of doing just that. The study reveals a competition mechanism used by human cancer cells for killing their neighbors and demonstrates that combining substances that block this mechanism with chemotherapy results in more effective tumor elimination. These findings may lead to the development of novel cancer therapies. (2019-07-24)

Cellular soldiers designed to kill cancer cells that get loose during surgery
Biomedical engineers at Vanderbilt University have discovered a method to track down and kill escaping cancer cells during tumor removal surgeries. The method, which uses the body's own defenses in the form of modified lipid nanoparticles adhered to white blood cells, could preventing metastasis and save lives. (2019-07-24)

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