Current COPD News and Events

Current COPD News and Events, COPD News Articles.
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New strategy blocks chronic lung disease in mice
A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease. (2021-02-23)

Researchers develop algorithm to find possible misdiagnosis
Researchers from the University of Copenhagen have developed an algorithm that can identify patients who may have been wrongly diagnosed. With the help of digital disease history, the algorithm is able to register disease trajectories that differ so much from normal trajectories that there may be a misdiagnosis. The algorithm has been developed on the basis of data from several hundreds of thousands of COPD patients. (2021-02-15)

Computer can determine whether you'll die from COVID
Using patient data, artificial intelligence can make a 90 percent accurate assessment of whether a person will die from COVID-19 or not, according to new research at the University of Copenhagen. Body mass index (BMI), gender and high blood pressure are among the most heavily weighted factors. The research can be used to predict the number of patients in hospitals, who will need a respirator and determine who ought to be first in line for a vaccination. (2021-02-05)

NIH study shows hyaluronan is effective in treating chronic lung disease
Researchers at the National Institutes of Health and their collaborators found that inhaling unfragmented hyaluronan improves lung function in patients suffering from severe exacerbation of chronic obstructive pulmonary disease (COPD). Hyaluronan, a sugar secreted by living tissue that acts as a scaffold for cells, is also used in cosmetics as a skin moisturizer and as a nasal spray to moisturize lung airways. Utilized as a treatment, hyaluronan decreased the number of days in the hospital. (2021-02-01)

CU Anschutz scientists reverse deadly impacts of asthma in mice
Excess mucus in the lungs can be fatal for asthma patients, but scientists at the University of Colorado Anschutz Medical Campus have broken up those secretions at the molecular level and reversed their often deadly impacts. (2021-01-13)

Drug discovery study identifies promising new compound to open constricted airways
In a preclinical study led by the University of South Florida, researchers identified and characterized 18 new compounds (agonists) that activate bitter taste receptor subtype TAS2R5 to promote relaxation of human airway smooth muscle cells. The cross-disciplinary team found 1,10 phenanthroline-5,6-dione (T5-8 for short) was 1,000 times more potent than some of the other bronchodilator agonists tested, and it demonstrated marked effectiveness in human airway smooth muscle cells grown in the laboratory. (2021-01-04)

Healthy muscles are a carrot on a string for healthy lungs
Scientists show effectiveness of carrot-based Japanese herbal medicine called ''Ninjin'yoeito'' in improving muscle atrophy in the hind legs of mice exposed to cigarette smoke through an increased expression of PGC-1α, positioning the medicine as a potential treatment for sarcopenia frailty-related complications with chronic obstructive pulmonary disease (COPD). Their findings were published online in the international scientific journal ''International Journal of Chronic Obstructive Pulmonary Disease'' on November 27, 2020. (2020-12-02)

Insulators in Alberta at higher risk of chest infections, COPD: study
Construction workers in Alberta, Canada who work with hazardous insulation materials are much more likely to be affected by repeated chest infections and chronic obstructive pulmonary disease (COPD), according to new research published in the International Journal of Environmental Research and Public Health. (2020-11-26)

Gut microbiome link to deadly lung disease
Research led by the Centenary Institute, the University of Technology Sydney and the University of Queensland has shown for the first time a link between chronic obstructive pulmonary disease (COPD), an often fatal lung condition, and the gut microbiome. (2020-11-19)

Home oxygen therapy for adults with COPD and ILD: New ATS clinical practice guideline
The latest clinical practice guideline on home oxygen therapy addresses long-term and ambulatory oxygen therapy for adults with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) and includes the most comprehensive review of the evidence of any oxygen guideline to date. (2020-11-17)

With or without allergies, outcomes similar for hospitalized patients with COVID-19
A new study being presented at this year's virtual American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting examines hospital data to determine if those with allergic conditions had more severe COVID-related disease than those without. (2020-11-13)

Vaping may increase respiratory disease risk by more than 40%: BU study
A growing body of evidence points to the health risks of using e-cigarettes (or ''vaping''). But because e-cigarettes are marketed as a less harmful alternative to traditional cigarettes, it has been difficult to tell whether the association between vaping and disease is just a matter of smokers switching to vaping when they start experiencing health issues. (2020-11-12)

Asthmatics working in dusty environments risk a trip to the hospital
Working in farming or the wood industry while suffering from asthma is not a good combination. This is because it increases the risk of being hospitalised again with asthma. This is shown by a new study from Aarhus University. (2020-11-09)

Researchers examine if online physician reviews indicate clinical outcomes
Dr. Atanu Lahiri and Dr. Zhiqiang Zheng studied the relationship between online reviews of physicians and their patients' actual clinical outcomes. They wanted to know how much consumers can rely on the reviews, specifically in regard to chronic-disease care. (2020-11-09)

Promising therapeutic approach against COPD
Chronic obstructive pulmonary disease (COPD) is one of the most common and deadliest diseases worldwide. Until today, COPD is not curable. Researchers at Helmholtz Zentrum München and at the German Cancer Research Center (DKFZ) have now succeeded in curing COPD in mice exposed to chronic cigarette smoke. Their goal is to test the novel therapeutic approach in human clinical trials over the next few years. (2020-11-04)

Healthcare app reduces symptoms of COPD compared to regular treatment
A Southampton-developed healthcare app that helps people with Chronic Obstructive Pulmonary Disease (COPD) manage their condition can speed up recovery after hospital admission and reduce flare-ups of symptoms, a newly published study has shown. (2020-10-30)

Face masks unlikely to cause over-exposure to CO2, even in patients with lung disease
New research findings contradict statements linking wearing face masks to carbon dioxide poisoning by trapping CO2. During the COVID-19 pandemic the wearing of face masks has become a highly political issue with some individuals falsely claiming that wearing face masks may be putting people's health at risk. The study published in the Annals of the American Thoracic Society shows otherwise. (2020-10-02)

Cannabinoids associated with negative respiratory health effects in older adults with COPD
Cannabinoids, a class of prescription pills that contain synthetically-made chemicals found in marijuana, are associated with a 64 per cent increase in death among older adults with chronic obstructive pulmonary disease (COPD), according to the first published data on the impact of cannabinoids on the respiratory health of individuals with the lung disease. (2020-09-30)

Measuring muscle strength provides insights regarding weakness in older adults
Isokinetic dynamometry is a major tool in the measurement of muscle strength in the fields of sports medicine, orthopedic and neurological rehabilitation and exercise physiology. Its use in older individuals now extends far beyond orthopedics to such conditions as chronic obstructive pulmonary disease (COPD) and stroke. In a collection of articles published in Isokinetics and Exercise Science, experts address its validity, reliability and responsiveness in older adults. (2020-09-30)

Study demonstrates SARS-CoV-2 emergence was associated with a large drop in the circulation of other respiratory viruses during the first wave
Analysis of samples taken to test for respiratory viruses over the past five years suggests that the emergence of SARS-CoV-2 was associated with a large drop in circulation of other common respiratory viruses during the first wave. The study, presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID), is by Dr Stephen Poole, BRC Clinical Research Fellow from the Southampton NIHR BRC, Southampton, UK, and colleagues. (2020-09-25)

COPD program decreases 30-day hospital readmission, may increase mortality
The 30-day readmission rate for patients with chronic obstructive pulmonary disease has decreased but the mortality rate has increased. Hospitals, in seeking to avoid financial penalties by reducing readmissions, may inadvertently affect minority and disadvantaged patients. (2020-09-10)

Researchers draw more links between vaping, smoking, young people, and coronavirus
Vapers, smokers, and non-smokers with chronic conditions are all at higher risk for COVID-19. The scientific explanation behind this is complex and not yet certain -- but it may boil down to an enzyme known as ACE2, that lives on the surface of many cells in the lungs and serves as the entry point for the coronavirus. (2020-09-09)

Rutgers-led national survey uncovers doctors' misconceptions about nicotine risks
Most doctors misperceive the risks of nicotine, the addictive chemical in tobacco products, according to a Rutgers-led national survey. (2020-09-09)

First review of SARS-CoV-2 and COVID-19 infection models
The first comprehensive review of all relevant animal and cellular models of SARS-CoV-2 infection and COVID-19 aims to assist with fast-tracking ongoing research into new preventions and treatments. (2020-08-24)

New practice guidelines on non-invasive ventilation in chronic stable Hypercapnic COPD
A subcommittee of the American Thoracic Society Assembly in Sleep and Respiratory Neurobiology has released new clinical practice guidelines to help advise clinicians on the optimal management of patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. Hypercapnia is the buildup of carbon dioxide in the bloodstream. (2020-08-17)

Protein produced by the nervous system may help treatments for inflammatory diseases
A Rutgers-led team discover a protein produced by nervous system may be key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD) (2020-08-17)

Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. Researchers have now identified certain lung-related factors that may help to predict an individual smoker's fracture risk. The findings are published in the Journal of Bone and Mineral Research. (2020-08-05)

COPD underdiagnosed in older adults, but can be managed
''Recognizing and Treating COPD in Older Adults'' the latest issue of the What's Hot newsletter from The Gerontological Society of America, addresses what is known about the prevalence, incidence, and impact of chronic obstructive pulmonary disease (COPD) in older adults. (2020-08-03)

Researchers find increase in comorbidities among hospitalized patients with heart failure
Melissa Caughey, PhD, instructor in the UNC/NC State Joint Department of Biomedical Engineering, is the senior author of a recently published study that shows an increase in comorbidities and mortality risk among hospitalized patients with acute decompensated HFpEF and HFrEF. (2020-07-30)

Study says inhalers ok to use amid COVID-19 concerns
University of Huddersfield researchers find that the benefits of inhalers for asthma sufferers outweigh the risks of contracting coronavirus, following concerns raised after WHO warned that steroids could reduce immunity. (2020-07-09)

New research confirms higher rates of new coronavirus in Latinx populations
In a new analysis of SARS-CoV-2, the virus that causes COVID-19, test results for nearly 38,000 people has found a positivity rate among Latinx populations about 3 times higher than for any other racial and ethnic group. (2020-06-23)

Lung development may explain why some non-smokers get COPD and some heavy smokers do not
According to a new study, people with small airways relative to the size of their lungs may have a lower breathing capacity and, consequently, an increased risk for COPD -- even if they don't smoke or have any other risk factors. The study, funded in part by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, will publish in the June 9 issue of JAMA. (2020-06-09)

Undersized airways may explain why nonsmokers get COPD
A mismatch between airway and lung size may explain why some nonsmokers get COPD and some heavy smokers do not, according to a new study from Columbia University Irving Medical Center. (2020-06-09)

Compact electronic nose to identify human lung diseases
Researchers from Russia and Italy have proposed a compact sensor system that can implement the functionality of the electronic nose and developed a reproducible technology for its manufacture. This device is designed as flexible electronics that can analyze exhaled air, as well as identify pathologies of the respiratory tract and organs. (2020-05-14)

Is pulmonary rehab after hospitalization for COPD associated with better survival?
Claims data for nearly 200,000 Medicare patients were used to examine the association between starting pulmonary rehabilitation within 90 days of being hospitalized for chronic obstructive pulmonary disease (COPD) and survival after one year. Pulmonary rehabilitation involves exercise training and self-management education. (2020-05-12)

COPD and smoking associated with higher COVID-19 mortality
Current smokers and people with chronic obstructive pulmonary disease (COPD) have an increased risk of severe complications and higher mortality with COVID-19 infection, according to a new study published May 11, 2020 in the open-access journal PLOS ONE by Jaber Alqahtani of University College London, UK, and colleagues. (2020-05-11)

Benefits of higher doses of certain medicines fail to justify costs and risks, study shows
Clinical trial data behind drug dose recommendations for elevated cholesterol and chronic obstructive pulmonary disease illustrate how larger doses may not be worth the extra costs for many types of patients. (2020-05-05)

Different trigger points for seeking healthcare may explain gender divide
Men might not be more reluctant to see a doctor than women are, as is popularly believed, but may simply have different trigger points for seeking healthcare, suggests research published online in the Journal of Epidemiology & Community Health. (2020-04-30)

COPD as a lung stem cell disease
Two internationally renowned stem cell researchers at the University of Houston have found an abundance of abnormal stem cells in the lungs of patients who suffer from Chronic Obstructive Pulmonary Disease (COPD), a leading cause of death worldwide. The team, who used single cell cloning of lung stem cells to make their discovery, is now targeting the cells for new therapeutics. (2020-04-15)

/LAMA combination therapy more effective for COPD patients with exercise intolerance
Clinicians grappling with the pharmacologic management of COPD in patients complaining of exercise intolerance or dyspnea now have new guidance. The American Thoracic Society has published an official clinical practice guideline in which a panel of experts strongly recommended LABA/LAMA combination therapy over LABA or LAMA alone. The complete guideline detailing all the recommendations was posted online ahead of print in the American Journal of Respiratory and Critical Care Medicine. (2020-04-14)

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