Current Cannabinoids News and Events

Current Cannabinoids News and Events, Cannabinoids News Articles.
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Cannabis could reduce fentanyl use, reduce overdose risk: Study
New research suggests that cannabis use by people in care for opioid addiction might improve their treatment outcomes and reduce their risk of being exposed to fentanyl in the contaminated unregulated drug supply. (2020-12-18)

Experimental vaccine can counter dangerous effects of synthetic cannabinoids
Made in clandestine laboratories and sold widely across the United States, the diverse class of drugs known as synthetic cannabinoids presents a growing public health threat. In a new study, Scripps Research scientists have devised a way to deactivate these designer drugs after they've been administered--offering a potential path for treating addiction and overdose. (2020-12-16)

Gut microbiota plays a role in brain function and mood regulation
Depression is a mental disorder that affects more than 264 million people of all ages worldwide. Understanding its mechanisms is vital for the development of effective therapeutic strategies. Scientists from the Institut Pasteur, Inserm and the CNRS recently conducted a study showing that an imbalance in the gut bacterial community can cause a reduction in some metabolites, resulting in depressive-like behaviors. These findings, which show that a healthy gut microbiota contributes to normal brain function, were published in Nature Communications on December 11, 2020. (2020-12-11)

Certain CBD oils no better than pure CBD at inhibiting certain cancer cell lines
Cannabidiol (CBD) oils are equally or less effective at inhibiting the growth of certain cancer cells compared to pure CBD, according to Penn State College of Medicine researchers. The results of their recent study indicate that future research into the clinical applications of cannabinoids should include an analysis of whether the pure cannabinoid compound or intact plant material is more effective at achieving the therapeutic effect. (2020-11-17)

Rethinking the link between cannabinoids and learning
Animals with altered cannabinoid signalling exhibit various motor and cognitive impairments, including deficits in learning and memory. A new study reveals an unexpected culprit for these effects - behavioral state. (2020-10-20)

Cannabinoids associated with negative respiratory health effects in older adults with COPD
Cannabinoids, a class of prescription pills that contain synthetically-made chemicals found in marijuana, are associated with a 64 per cent increase in death among older adults with chronic obstructive pulmonary disease (COPD), according to the first published data on the impact of cannabinoids on the respiratory health of individuals with the lung disease. (2020-09-30)

Cannabis data lacking, but machine learning could help
Everyone's heard of THC and CBD. But many other active compounds in cannabis interact to influence its effects. A new study confirms that those compounds are seldom tested for, and strain name is not indicative of potency or chemical makeup. Machine learning techniques could help fill the knowledge gap. (2020-09-29)

University of South Carolina study reveals how cannabinoids may be useful to prevent colon cancer
Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are caused by inflammation of the gastrointestinal tract. Patients with IBD are at a higher risk of developing colorectal cancer. A UofSC study shows that THC suppressed inflammation in the colon, preventing the onset of cancers caused by a carcinogen. (2020-09-15)

New UBCO study examines pain tolerance among cannabis users
A recent study examining pain among cannabis users suggests that--unlike long-term opioid use--regular cannabis use does not appear to increase pain sensitivity. Doctoral student Michelle St. Pierre, who conducts research in the psychology department at UBC Okanagan, recently published a study looking for differences in pain tolerance of people who frequently use cannabis compared to those who don't. (2020-09-10)

UofSC researchers reveal how THC may treat acute respiratory distress syndrome
Acute Respiratory Distress Syndrome (ARDS), when caused by a bacterial toxin known as Staphylococcal enterotoxin, can be completely prevented by treatment with Δ9-tetrahydrocannabinol (THC), a cannabinoid found in the cannabis plant. (2020-08-26)

Cannabinoids may affect activity of other pharmaceuticals
Cannabinoid-containing products may alter the effects of some prescription drugs, according to Penn State College of Medicine researchers. They published information that could help medical professionals make safe prescribing choices for their patients who use prescription, over-the-counter or illicit cannabinoid products. (2020-08-03)

Marijuana use while pregnant boosts risk of children's sleep problems
As many as 7% of moms-to-be use marijuana while pregnant, and that number is rising fast as more use it to quell morning sickness. But new research suggests such use could have a lasting impact on the fetal brain, influencing children's sleep for as much as a decade. (2020-07-02)

Researchers flush out worrying trend of designer drug use
In a sign that designer drugs are becoming more prevalent in Australia, synthetic cathinones -- commonly known as 'bath salts' -- have been detected in the nation's wastewater in the largest study of its kind in the country. (2020-06-15)

Marijuana concentrates spike THC levels but don't boost impairment
A study of 121 regular users of legal market cannabis found that higher potency does not necessarily mean greater intoxication. It also found that while balance and memory are impaired immediately after use, that impairment fades within in an hour. (2020-06-10)

Study shows cannabis temporarily relieves PTSD symptoms
People suffering from post-traumatic distress disorder report that cannabis reduces the severity of their symptoms by more than half, at least in the short term, according to a recent study led by WSU psychology professor Carrie Cutler. (2020-06-09)

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study finds
Cannabis use makes young brains more sensitive to the first exposure to cocaine, according to a new study on rodents led by scientists at Columbia University and the University of Cagliari in Italy. By monitoring the brains of both adolescent and adult rats after giving them synthetic psychoactive cannabinoids followed by cocaine, the research team identified key molecular and epigenetic changes that occurred in the brains of adolescents -- but not adults. (2020-04-20)

Study: Frequent cannabis users are way too high ... in their estimates of cannabinoids
Researchers surveyed nearly 500 Hash Bash attendees, asking them to fill out a 24-item questionnaire. Participants were asked to fill in, in milligrams, the amounts they considered to be effective doses of THC and CBD. They were way off. (2020-04-15)

Labeling of cannabidiod products becoming a public health concern
The need for accurate and informative labeling of hemp and hemp-derived cannabidiol (CBD) products is a critical public health issue. (2020-03-25)

Study indicates vaporized cannabis creates drug-seeking behavior
The WSU research team found that rats with regular access to cannabis seek more of the substance and tend to show increased drug-seeking behavior when cannabis is absent. (2020-03-24)

Using cannabinoids to treat acute pain
A new systematic review and meta-analysis showed a small but significant reduction in subjective pain scores for cannabinoid treatment compared to placebo in patients experiencing acute pain. (2020-03-23)

Scientists find sexual dimorphism in cannabinoid 1 receptor expression in mice
A research team led by Dr. WANG Feng from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences demonstrated that CB1R mRNA expression displays a sexually dimorphic pattern in several regions in the adult mouse brain. (2020-03-17)

Drug interactions with cannabinoids: 5 things to know
A practice article provides 5 things to know on how drugs can interact with cannabinoids in CMAJ (Canadian Medical Association Journal). (2020-03-02)

Cases of poisoning: Liquids containing cannabidiols for e-cigarettes can be manipulated
The health risks of e-cigarettes have come into focus after the deaths of several 'vapers' due to lung injury in the USA recently. These health risks were discussed in press reports on eight young people who were poisoned in Bremerhaven in October 2019. Patients suffered from convulsive seizures, impaired consciousness and memory, and heart palpitations. (2020-02-26)

Cannabis compound acts as an antibiotic 
Public health agencies worldwide have identified antibiotic resistance of disease-causing bacteria as one of humanity's most critical challenges. However, scientists haven't discovered a new class of antibiotics in more than 30 years. Now, researchers reporting in ACS Infectious Diseases have uncovered the hidden antibiotic potential of a non-psychoactive cannabis compound called cannabigerol (CBG), which helped control methicillin-resistant Staphylococcus aureus (MRSA) infections in mice. (2020-02-26)

McMaster researchers uncover hidden antibiotic potential of cannabis
The research team found that CBG had antibacterial activity against drug-resistant MRSA. It prevented the ability of that bacteria to form biofilms, which are communities of microorganisms that attach to each other and to surfaces; and it destroyed preformed biofilms and cells resistant to antibiotics. CBG achieved this by targeting the cell membrane of the bacteria. These findings in the laboratory were supported when mice with an MRSA infection were given CBG. (2020-02-26)

Smoke two of these and call me in the morning? Not quite, study finds
Researchers surveyed cannabis users about beliefs on marijuana's effectiveness in treating certain medical conditions. The results reveal a big discrepancy. (2020-01-30)

New insight into how cannabidiol takes effect in the brains of people with psychosis
Researchers from King's College London have shown that cannabidiol (CBD) alters the brain activity in people with psychosis during memory tasks, making it more similar to the activation seen in people without psychosis during the same tasks. (2020-01-28)

Research suggests potential link between marijuana and heart risks
As more states legalize marijuana for both medicinal and recreational use and use increases nationwide, cardiologists should advise patients about the potential risks, including effects of marijuana with some commonly prescribed cardiovascular medications, according to a research review published today in the Journal of the American College of Cardiology. (2020-01-20)

An estimated 2 million people with heart disease have used marijuana, finds study
A new study estimates that more than 2 million Americans with heart disease have used marijuana, but the cardiovascular effects of the drug are not fully understood. (2020-01-20)

Medicinal cannabis may not ease sleep problems in the long run
Medicinal cannabis might not ease sleep problems in people with chronic pain over the long term, because frequent users might build up tolerance to its sleep-inducing effects, suggests preliminary research published online in BMJ Supportive & Palliative Care. (2020-01-20)

Cannabis reduces headache and migraine pain by nearly half
Inhaled cannabis reduces self-reported headache severity by 47.3% and migraine severity by 49.6%, according to a recent study by Washington State University researchers published in the Journal of Pain. The study also found no evidence that cannabis caused 'overuse headache,' a pitfall of more conventional treatments. The researchers did see patients using larger doses of cannabis over time, indicating they may be developing tolerance to the drug. (2019-11-25)

CBD, THC use during early pregnancy can disrupt fetal development
A new study published in Scientific Reports, a Nature Research journal, shows how a one-time exposure during early pregnancy to cannabinoids (CBs) -- both synthetic and natural -- can cause growth issues in a developing embryo. This is the first research to show such a connection in mammals. (2019-11-05)

Some CBD products may yield cannabis-positive urine drug tests
Small study concludes that caution is warranted for users of 'high CBD, low THC' cannabis products. (2019-11-04)

World first on-the-spot test for synthetic drug 'spice' developed at University of Bath
A simple saliva test to detect if someone has recently taken the street drug ''spice'' has been developed at the University of Bath - the first such test ever created. (2019-10-30)

The frostier the flower, the more potent the cannabis
Cannabis flowers with the most mushroom-shaped hairs pack the biggest cannabinoid and fragrance punch, according to new research from the University of British Columbia. (2019-10-28)

The Lancet Psychiatry: Insufficient evidence that medicinal cannabinoids improve mental health
The most comprehensive analysis of medicinal cannabinoids and their impact on six mental health disorders -- combining 83 studies including 3,000 people -- suggests that the use of cannabinoids for mental health conditions cannot be justified based on the current evidence. This is due to a lack of evidence for their effectiveness, and because of the known risks of cannabinoids. (2019-10-28)

Older adults with COPD more likely to use synthetic cannabinoids, study finds
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that's often associated with a variety of health problems, including chronic muscle pain and insomnia. Psychoactive drug classes, like cannabinoids, are often prescribed to help reduce pain, promote sleep and decrease breathlessness. A study published today in Drugs & Aging found that older adults with COPD were twice as likely to use prescription synthetic oral cannabinoids compared to older adults without COPD, raising safety concerns. (2019-09-23)

Cannabis may hold promise to treat PTSD but evidence lags behind use
As growing numbers of people are using cannabis to treat post-traumatic stress disorder (PTSD), a new UCL study published in the Journal of Dual Diagnosis reports that prescriptions are not backed up by adequate evidence. (2019-09-03)

Survey reveals skyrocketing interest in marijuana and cannabinoids for pain
Millennials lead the escalating interest in marijuana and cannabinoid compounds for managing pain -- with older generations not far behind -- yet most are unaware of potential risks. 75% of Americans who expressed interest in using marijuana or cannabinoids to address pain are under the impression they are safer or have fewer side effects than opioids or other medications, according to a nationwide survey commissioned by American Society of Anesthesiologists in conjunction with September's Pain Awareness Month. (2019-08-26)

A paradoxical proinflammatory effect of endocannabinoids in the brain discovered
The results of the study in mice are contrary to what had been observed to date in other areas of the brain where endocannabinoids play an anti-inflammatory role. (2019-07-30)

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