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Current Capsaicin News and Events, Capsaicin News Articles.
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Hot chilli may unlock a new treatment for obesity
University of Adelaide researchers have discovered a high-fat diet may impair important receptors located in the stomach that signal fullness. (2015-08-18)

Regular consumption of spicy foods linked to lower risk of death
Eating spicy food more frequently as part of a daily diet is associated with a lower risk of death, suggests a new study published in The BMJ this week. The association was also found for deaths from certain conditions such as cancer, and ischaemic heart and respiratory diseases. (2015-08-04)

Body's response to spicy foods guides design of new pain relief drugs
UC Davis researchers have identified the molecular interactions that allow capsaicin to activate the body's primary receptor for sensing heat and pain, paving the way for the design of more selective and effective drugs to relieve pain. (2015-06-09)

One exposure to e-cigarette use diminishes cough reflex sensitivity
With just one exposure to electronic-cigarette (e-cigarette) vapor, participants in a study of 30 healthy subjects demonstrated a diminishment of cough reflex sensitivity. The study was presented at the 2015 American Thoracic Society International Conference. (2015-05-17)

Chili peppers hold promise of preventing liver damage and progression
Results revealed today at the International Liver Congress™ 2015 show that the daily consumption of capsaicin, the active compound of chili peppers, was found to have beneficial effects on liver damage. (2015-04-23)

Enhancing mechanism of capsaicin-evoked pain sensation
Drs. Takayama and Tominaga in National Institute for Physiological Sciences -- Okazaki Institute for Integrative Bioscience -- clarified that an interaction between capsaicin receptor TRPV1 and chloride channel anoctamin 1 causes enhancement of the capsaicin-evoked pain sensation in mice in collaboration with Dr. Uta, Toyama University, and Dr. Furue, NIPS. This result will be published in the Proceedings of the National Academy of Sciences of the United States of America. (2015-04-06)

Magnetic brain stimulation
Magnetic nanoparticles could allow brain stimulation without wires. (2015-03-12)

'Ouch zone' in the brain identified
Activity in a brain area known as the dorsal posterior insula is directly related to the intensity of pain, an Oxford University brain imaging study people has found. These results could help detect pain in people with limited communication abilities. The research team now plans to verify these results by attempting to switch off this brain region in relevant patients suffering from intractable pain. (2015-03-09)

What's next in diets: Chili peppers?
A large percentage of the world's population -- fully one third, by the World Health Organization's estimates -- is currently overweight or obese. This staggering statistics has made finding ways to address obesity a top priority for many scientists around the globe, and now a group of researchers at the University of Wyoming has found promise in the potential of capsaicin -- the chief ingredient in chili peppers -- as a diet-based supplement. (2015-02-08)

Cost and effect: Cheaper remedies should rule for diabetes nerve pain, U-M experts say
Millions of people with diabetes take medicine to ease shooting, burning nerve pain, and new research suggests that many medicines can offer relief. But since some of those medicines cost nearly 10 times as much as others, cost should be a crucial factor in deciding which medicine to choose for diabetic neuropathy, say University of Michigan experts. (2014-11-05)

New cough study demonstrates diphenhydramine to inhibit cough reflex with Dr. Cocoa form
Dr. Peter Dicpinigaitis will be explaining the cough study results that show diphenhydramine's efficacy for cough symptom relief at the infirst Healthcare/Dr. Cocoa for Children exhibit booth (No. 1521) at this week's American Academy of Pediatrics Annual Meeting, Oct. 11-14, in San Diego. Dr. Dicpinigaitis will formally present the findings during these times: Saturday, Oct. 11, at 1:30 p.m. and 3 p.m., and Sunday, Oct. 12, at 10:30 a.m., 1:30 p.m. and 3 p.m. (2014-10-11)

Scientists discover pain receptor on T-cells
Researchers at University of California, San Diego School of Medicine have discovered that T-cells -- a type of white blood cell that learns to recognize and attack microbial pathogens -- are activated by a pain receptor. (2014-10-05)

Treating pain by blocking the 'chili-pepper receptor'
Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many kinds of pain, which can be caused by inflammation or other problems. They reported their progress on the compound, which is being tested in clinical trials, in ACS' Journal of Medicinal Chemistry. (2014-08-20)

Pepper and halt: Spicy chemical may inhibit gut tumors
Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin -- the active ingredient in chili peppers -- produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors. (2014-08-01)

Discovery of a new means to erase pain
A study published in the scientific journal Nature Neuroscience by Yves De Koninck and Robert Bonin, two researchers at Université Laval, reveals that it is possible to relieve pain hypersensitivity using a new method that involves rekindling pain so that it can subsequently be erased. This discovery could lead to novel means to alleviate chronic pain. (2014-07-09)

Blocking pain receptors found to extend lifespan in mammals
Chronic pain in humans is associated with worse health and a shorter lifespan, but the molecular mechanisms underlying these clinical observations have not been clear. A study published in Cell reveals that the activity of a pain receptor called TRPV1 regulates lifespan and metabolic health in mice. The study suggests that pain perception can affect the aging process and reveals novel strategies that could improve metabolic health and longevity in humans. (2014-05-22)

Blocking pain receptors extends lifespan, boosts metabolism in mice
Chronic pain is known to shorten lifespan, and pain tends to increase with age. But is there a relationship between pain and longevity? UC Berkeley and Salk researchers have found that mice lacking the capsaicin pain receptor live around 14 percent longer than other mice, and they retain a more youthful metabolism as well. Receptor blockers could not only relieve pain, but increase lifespan, improve metabolic health and help diabetics and the obese. (2014-05-22)

Brain uses serotonin to perpetuate chronic pain signals in local nerves
Setting the stage for possible advances in pain treatment, researchers at The Johns Hopkins University and the University of Maryland report they have pinpointed two molecules involved in perpetuating chronic pain in mice. The molecules, they say, also appear to have a role in the phenomenon that causes uninjured areas of the body to be more sensitive to pain when an area nearby has been hurt. (2014-01-23)

Structure of key pain-related protein unveiled
In a technical tour de force, UC San Francisco scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat. (2013-12-04)

Less 'brown fat' could help explain why a fifth of the world's population is highly susceptible to Type 2 diabetes
Lower amounts of brown adipose tissue (BAT, or (2013-11-11)

Personality may predict if you like spicy foods
Certain aspects of an individual's personality may be a determining factor in whether they like their food plain and bland or spicy and hot, according to research presented at the 2013 Institute of Food Technologists Annual Meeting & Food Expo. (2013-07-17)

Chili peppers spark discovery
As research efforts go, this one is high risk. Which is to say, it could easily fail. And it's high reward. Meaning it could provide some relief to concussions and subsequent health effects seen in athletes, soldiers and other head-injury victims. The National Football League thinks enough of the work that its charitable arm has given Krzysztof Czaja (pronounced K-shish-toff Chai-uh), a Washington State University neuroscientist, $100,000 to keep looking. (2013-02-04)

Method patent issued for investigational new class of pain medication
The US Patent and Trademark Office recently issued a patent to the US Department of Health and Human Services involving resiniferatoxin, or RTX, an experimental compound that represents a potential new class of drugs to alleviate the intractable pain that can occur in people with advanced cancer, severe arthritis, and other extremely chronic conditions. (2013-01-25)

Mindfulness meditation may relieve chronic inflammation
People suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma -- in which psychological stress plays a major role -- may benefit from mindfulness meditation techniques, according to a study by University of Wisconsin-Madison neuroscientists with the Center for Investigating Healthy Minds at the Waisman Center. (2013-01-16)

Itchy wool sweaters explained
Johns Hopkins researchers have uncovered strong evidence that mice have a specific set of nerve cells that signal itch but not pain, a finding that may settle a decades-long debate about these sensations, and, if confirmed in humans, help in developing treatments for chronic itch, including itch caused by life-saving medications. (2013-01-02)

Secondhand smoke impairs vital cough reflex in kids
Research from the Monell Center reveals that exposure to secondhand smoke decreases sensitivity to cough-eliciting respiratory irritants in healthy children and adolescents. The findings may help to explain why children of smokers are more likely to develop respiratory diseases and also are more likely to experiment with smoking during adolescence. (2012-08-20)

Neural precursor cells induce cell death in certain brain tumors
Neural precursor cells in the young brain suppress certain brain tumors such as high-grade gliomas, especially glioblastoma, which are among the most common and most aggressive tumors. Now researchers of the Max Delbrück Center and Charité - Universitätsmedizin Berlin have deciphered the underlying mechanism of action with which neural precursor cells protect the young brain against these tumors. (2012-07-23)

Marshall University scientist awarded NIH grant for lung cancer research
A Marshall University faculty member has been awarded a three-year, $426,000 grant by the National Institutes of Health (NIH) to further her research to determine if the nutritional agent capsaicin -- the active ingredient in chili peppers -- can improve the anti-cancer activity of the commonly used chemotherapy drug cisplatin in patients with small cell lung cancer. (2012-07-20)

Sweet minty relief for cough
New findings from the Monell Center suggest that sucrose and menthol, ingredients commonly regarded as flavorings in cough drops or syrup, each act independently to reduce coughing. Implications range from medicinal to tobacco products. (2012-06-11)

Hot sauce ingredient reduces 'beer belly' fat as a weight-loss surgery alternative
According to research from Brigham and Women's Hospital, the ingredient that gives hot sauce its heat could play a role in the future of weight loss. (2012-05-09)

Hot pepper compound could help hearts
The food that inspires wariness is on course for inspiring even more wonder from a medical standpoint as scientists today reported the latest evidence that chili peppers are a heart-healthy food with potential to protect against the No. 1 cause of death in the developed world. The report was part of the 243rd National Meeting and Exposition of the American Chemical Society (ACS), the world's largest scientific society, being held here this week. (2012-03-27)

Neuron memory key to taming chronic pain
A team of researchers led by McGill neuroscientist Terence Coderre, who is also affiliated with the Research Institute of the McGill University Health Centre, has found the key to understanding how memories of pain are stored in the brain. More importantly, the researchers are also able to suggest how these memories can be erased, making it possible to ease chronic pain. (2012-02-13)

Muscle relaxants and neuromodulators for managing RA pain: Many options, but no clear successes
Pain management is a high priority for patients with rheumatoid arthritis, so three researchers in Australia analyzed existing study data to see whether two different classes of drugs can help. When looking at muscle relaxants, they discovered that neither the benzodiazepine agents, diazepam and triazolam, nor the non- benzodiazepine agent, zopiclone, reduce pain when taken for one to 14 days. However, even this short use was associated for both agents with drowsiness and dizziness. (2012-01-17)

DMP for diabetes type 2: Current guidelines indicate some need for revision
As a literature search for recommendations from current clinical practice guidelines of high methodological quality has shown, there is no compelling need for revision of any part of the disease management program for diabetes type 2. However, in its final report now published, IQWiG identified various aspects that could be supplemented and specified. (2012-01-03)

To turn up the heat in chilies, just add water
Hot chilies growing wild in dry environments produce substantially fewer seeds than non-pungent plants, but they are better protected against a seed-attacking fungus that is more prevalent in moist regions. (2011-12-20)

Research shows heat in chili peppers can ease sinus problems
Hot chili peppers are known to make people (2011-08-25)

Pain and itch connected down deep
Despite much research on pain receptors, investigators have only recently focused on itch and how the body distinguishes between itch and pain. This research, including new findings by UC Berkeley's Diana Bautista, show that the receptors responding to irritants actually work by triggering pain receptors, which in turn send signals to the brain that make us want to scratch. The connection suggests that new pain relievers under development may also help relieve intractable itch. (2011-05-02)

Study: Reasonable quantities of red pepper may help curb appetite
Spicing up your daily diet with some red pepper can curb appetite, especially for those who don't normally eat the popular spice, according to research from Purdue University. (2011-04-25)

Barrow TRPV1 research highlighted in Journal of Neuroscience
Research by a Barrow Neurological Institute scientist on the thermoregulatory effects of a receptor more commonly studied for its role in pain is the cover story in the Feb. 2 issue of the Journal of Neuroscience. (2011-02-01)

Hormel Institute study reveals capsaicin can act as cocarcinogen
The September cover story of the nation's leading cancer journal, Cancer Research, features a new study from the Hormel Institute, University of Minnesota, that links capsaicin, a component of chili peppers, to skin cancer. (2010-09-02)

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