Current Cardiomyocytes News and Events

Current Cardiomyocytes News and Events, Cardiomyocytes News Articles.
Sort By: Most Relevant | Most Viewed
Page 1 of 7 | 271 Results
Texas A&M researchers discover energy drinks' harmful effects on heart
A team of researchers, led by a Texas A&M University professor, has found that some energy drinks have adverse effects on the muscle cells of the heart. (2021-02-10)

Higher blood pressure over life span increases congestive heart failure risk in Black people
Starting with early childhood, otherwise healthy Black people show signs of slightly diminished heart muscle strength and a slightly higher blood pressure than their white counterparts, factors which may put them on a course for early development of congestive heart failure, Medical College of Georgia researchers report. (2021-02-08)

Stem cell study illuminates the cause of a devastating inherited heart disorder
Penn Medicine scientists have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM)-- one of multiple congenital disorders caused by inherited mutations in a gene called LMNA. The scientists used stem cell techniques to grow human heart muscle cells containing DCM-causing mutations in LMNA. They found that these mutations severely disrupt the structural organization of DNA in the nucleus of heart muscle cells. (2021-02-01)

Researchers map heart recovery after heart attack with great detail
Researchers from the Hubrecht Institute mapped the recovery of the heart after a heart attack with great detail. They found that cardiomyocytes play an important role in the intracellular communication after a heart attack. The researchers documented their findings in a database that is accessible for scientists around the world. This brings the research field a step closer to the development of therapies for improved recovery after heart injury. (2021-01-29)

Finding a way to stop chemotherapy from damaging the heart
There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests. (2021-01-25)

A study has demonstrated that omega-3 rich foods improve post-heart attack prognosis
A team of researchers from the Germans Trias i Pujol Hospital and Research Institute (IGTP) and the Hospital del Mar Medical Research Institute (IMIM) has shown that regularly consuming foods rich in omega-3 fatty acids, from both animal and vegetable origins, strengthens the heart's membranes and helps improve the prognosis in the event of a myocardial infarction. To arrive at these conclusions, they used data from 950 patients. (2020-10-27)

Reviving cells after a heart attack
Harvard SEAS researchers have unraveled potential mechanisms behind the healing power of extracellular vesicles and demonstrated their capacity to not only revive cells after a heart attack but keep cells functioning while deprived of oxygen during a heart attack. The researchers demonstrated this functionality in human tissue using a heart-on-a-chip with embedded sensors that continuously tracked the contractions of the tissue. (2020-10-14)

Computational approach to optimise culture conditions required for cell therapy
Collaboration by researchers in Singapore and Australia lead to first-of-its-kind computational biology algorithm that could enable more effective cellular therapies against major diseases. (2020-10-12)

Exosome treatment improves recovery from heart attacks in a preclinical study
Research in pigs shows that using the exosomes naturally produced from a mixture of heart muscle cells, endothelial cells and smooth muscle cells -- which were all derived from human induced pluripotent stem cells -- yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells. (2020-09-29)

Cell therapy designed to treat inflammatory bowel disease
The UPV/EHU's NanoBioCel research group has for many years been developing systems enabling cells to be used as drugs. Cell therapy raises hopes for treating those diseases for which there are as yet no effective pharmacological solutions. Biomaterials, a leading journal in the field of materials sciences and medicine, has just published the paper 'Multifunctional biomimetic hydrogel systems to boost the immunomodulatory potential of mesenchymal stromal cells'. (2020-09-28)

Mapping the human heart, cell by cell
Scientists have mapped and described the function of cells in six regions of the adult heart, providing a new foundation for studying heart disease. (2020-09-24)

A 'cell-less' therapy may regenerate heart tissue without cell transplant risks
Ling Gao and colleagues have developed a strategy that uses exosomes - tiny membrane-bound sacs secreted by cells - to mimic the heart-regenerating effects of cardiac cell transplants, while potentially avoiding risks associated with whole-cell transplants. (2020-09-16)

CNIC researchers discover a cell-cleaning system that keeps hearts healthy
The study published in Cell shows that macrophages, a type of immune cell, help cardiac cells to get rid of their waste material, and that this maintains the metabolic and contractile properties of the heart. (2020-09-15)

UC Davis researchers find a way to help stem cells work for the heart
Blocking an enzyme linked with inflammation makes it possible for stem cells to repair damaged heart tissue, new research from UC Davis Health scientists shows. (2020-09-09)

Fighting cardiovascular disease with acne drug
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg and Stanford University have found the cause of dilated cardiomyopathy - a leading cause of heart failure - and identified a potential treatment for it: a drug already used to treat acne. The study was published on 8 September in Cell Reports. (2020-09-08)

A soft-hearted approach to healing
Researchers at the University of Tsukuba and Keio University have clarified the roles of matrix stiffness and mechanotransduction as well as the signaling pathways in the transformation of cardiac fibroblasts into contractile cardiomyocytes and show that soft substrates comparable to native myocardium improve the efficiency of this cardiac reprogramming. This has potential for research into biomaterials and may lead to clinical advances in regenerative treatment for heart failure. (2020-08-30)

Gout treatment may aid patients with congenital heart disease
A drug used to treat gout, probenecid, may improve heart function in individuals with a particular heart defect, according to results from a small pilot study run by a University of Cincinnati researcher. Individuals with congenital univentricular circulation ran better and their heart performed better while taking probenecid. The change was small partially because of the small number of study participants. (2020-08-27)

Ageing heart cells offer clues to susceptibility of older people to severe COVID-19
Genes that play an important role in allowing SARS-CoV-2 to invade heart cells become more active with age, according to research published today in the Journal of Molecular and Cellular Cardiology. The findings could help explain why age is major risk factor for dying from COVID-19, with people over 70 years at greatest risk, and why the disease can cause heart complications in severe cases, including heart failure and inflammation of the heart. (2020-08-18)

SUTD researchers create heart cells from stem cells using 3D printing
SUTD researchers 3D printed a micro-scaled physical device to demonstrate a new level of control in the directed differentiation of stem cells, enhancing the production of cardiomyocytes. (2020-08-11)

New platform enables long-term tracking of stem cell-derived tissues after transplantation
A new platform reported on in STEM CELLS Translational Medicine (SCTM) will enable long-term tracking of cardiomyocytes produced from induced pluripotent stem cells (iPSCs) after implantation into the heart. (2020-07-23)

Research brief: Researchers 3D print a working heart pump with real human cells
In a groundbreaking new study, researchers at the University of Minnesota have 3D printed a functioning centimeter-scale human heart pump in the lab. The discovery could have major implications for studying heart disease, the leading cause of death in the United States killing more than 600,000 people a year. (2020-07-15)

COVID-19 and the heart: Searching for the location of the SARS-CoV-2 receptor
Nearly 20% of COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community. One hypothesis centers on the infection of the heart itself. To address this, MMRI Assistant Professor Dr. Nathan Tucker, in collaboration with the Broad Institute, the University of Pennsylvania, and Bayer US, report the distribution of the SARS-CoV-2 receptor in a manuscript published in Circulation. (2020-07-14)

Direct reprogramming: Defying the contemporary limitations in cardiac regeneration
Repair and regeneration of myocardium are the best possible therapy for the end-stage heart failure patients because the current therapies that can help restore the lost cardiomyocytes are limited to heart transplantation only. Emerging interests to directly reprogram a mammalian heart with minimal regenerative capacity holds a promising future in the field of cardiovascular regenerative medicine. (2020-06-22)

Scientists find optimal age of stem cells
Biophysicists from MIPT and Vladimirsky Moscow Regional Clinical Research Institute have determined the optimal age of reprogrammed stem cells suitable for restoring heart tissue. It spans the period roughly from day 15 until day 28 of maturation. (2020-05-26)

Image analysis technique provides better understanding of heart cell defects
Many patients with heart disease face limited treatment options. Fortunately, stem cell biology has enabled researchers to produce large numbers of cardiomyocytes, which may be used in drug screens and cell-based therapies. However, current image analysis techniques don't allow researchers to analyze heterogeneous, multidirectional, striated myofibrils typical of immature cells. In the Journal of Applied Physics, researchers showcase an algorithm that combines gradient methods with fast Fourier transforms to quantify myofibril structures in heart cells. (2020-05-19)

Switching on a key cancer gene could provide first curative treatment for heart disease
Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell regeneration. Since adult hearts cannot usually repair themselves once damaged, harnessing the power of this gene represents major progress towards the first curative treatment for heart disease. (2020-04-14)

UCI team demonstrates ability to supercharge cells with mitochondrial transplantation
UCI researchers have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. The team's study, published today in the Journal of the American Heart Association, suggests that mitochondrial transplantation could one day be employed to cure various cardiovascular, metabolic and neurodegenerative disorders -- and even offer a new approach to the treatment of cancer. (2020-03-23)

Changing what heart cells eat could help them regenerate
Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die. (2020-02-21)

Tracking a silent killer: New biomarker identified for arrhythmogenic cardiomyopathy
Scientists have identified a metabolic biomarker that could help track the progression of arrhythmogenic cardiomyopathy (AC) -- an inherited heart condition that can kill swiftly and without warning -- in a study of heart tissue and plasma from patients with AC. (2020-02-12)

Study reveals missing link in mechanisms underlying fight-or-flight response
Scientists map the molecular cascade behind heart function during fight-or-flight state. Findings solve longstanding biological puzzle. Results yield critical insights in adrenaline physiology that may inform other fields. Newly identified pathway can set stage for better targeted therapies to regulate heart muscle function. (2020-01-23)

An international study discovers a new origin of lymphatic vessels in the heart
A study published today in Development Cell opens the way to future research into the mechanism of lymphatic vessel formation in this new niche and the functional diversity of cardiac lymphatics. (2020-01-09)

Take heart: Pitt study reveals how relaxin targets cardiovascular disease
As a healthy heart ages, it becomes more susceptible to cardiovascular diseases. Though researchers have discovered that relaxin, an insulin-like hormone, suppresses atrial fibrillation (AF), inflammation, and fibrosis in aged rats, the underlying mechanisms of these benefits are still unknown. In a recent Scientific Reports paper, University of Pittsburgh researchers discuss how relaxin interacts with the body's signaling processes to produce a fundamental mechanism that may have great therapeutic potential. (2020-01-07)

SUTD scientists developed a sorting technology that isolates cells with high purity and viability
SUTD researchers developed a sheathless acoustic fluorescence activated cell sorting (aFACS) system by combining elasto-inertial cell focusing and highly focused traveling surface acoustic wave to sort cells with high recovery rate, purity, and cell viability. This novel microfluidic system provides a promising solution for single-cell level detection and isolation in biomedical applications that require sorted cells to be viable and functional for follow-on analysis and handling. (2019-12-16)

Tracking titin in real time
Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into muscle development as well as treating damaged muscles and heart disease. (2019-12-13)

A research team develop biotransistors able to hear small beats of live
Experts at the Institute for Bioengineering of Catalonia (IBEC), in collaboration with the Institute of Materials Science of Barcelona (ICMAB-CSIC), have achieved a new milestone. By developing a bio-platform that integrates in its core an organic electronic device called Electrolyte Gated Organic Field Effect Transistor (EGOFETs), researchers have been able to monitor the electrical signal of cells and micro-tissues during long periods of time. (2019-12-11)

Heart attack modeled with human stem cells
A model of ischemic heart disease was developed using human induced pluripotent stem cells (hiPSC). This model can provide a useful platform for developing effective drugs without sacrificing animals. (2019-11-07)

A kinase identified as possible target to treat heart failure
An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies. Failing human hearts showed reduced amounts of this kinase, and preclinical experiments showed that restoring the amount of this kinase in a kinase-depleted mouse model rescued the animal from heart failure. (2019-10-31)

Special cells contribute to regenerate the heart in Zebrafish
It is already known that zebrafish can flexibly regenerate their hearts after injury. An international research group led by Prof. Nadia Mercader of the University of Bern now shows that certain heart muscle cells play a central role in this process. The insights gained could be used to initiate a similar repair process in the human heart. (2019-10-23)

Novel nanoprobes show promise for optical monitoring of neural activity
Researchers at UC Santa Cruz have developed ultrasensitive nanoscale optical probes to monitor the bioelectric activity of neurons and other excitable cells. This novel readout technology could enable scientists to study how neural circuits function at an unprecedented scale by monitoring large numbers of individual neurons simultaneously. It could also lead to high-bandwidth brain-machine interfaces with dramatically enhanced precision and functionality. (2019-10-18)

Platform for lab-grown heart cells lets researchers examine functional effects of drugs
The human heart's energy needs and functions are difficult to reproduce in other animals; one new system looks to circumvent these issues and provide a functional view of how different treatments can help ailing cells in the heart following oxygen and nutrient deprivations. Researchers have unveiled a new silicon chip that holds human lab-grown heart muscle cells for assessing the effectiveness of new drugs. They discuss their work in this week's APL Bioengineering. (2019-08-13)

Page 1 of 7 | 271 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.