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Rich nations see virus rates fall quicker -- study
Richer countries were more likely to see rates of COVID-19 fall faster during the first wave of the pandemic, according to new research published in the journal Frontiers in Public Health. (2021-02-18)

Severe undercounting of COVID-19 cases in U.S., other countries estimated via model
A new machine-learning framework uses reported test results and death rates to calculate estimates of the actual number of current COVID-19 infections within all 50 U.S. states and 50 countries. Jungsik Noh and Gaudenz Danuser of the University of Texas Southwestern Medical Center present these findings in the open-access journal PLOS ONE on February 8, 2021. (2021-02-08)

Raised mortality from cardiac arrest in people with COVID-19
Sudden cardiac arrest is more often fatal in people with COVID-19, a new study shows. Those responsible for the research see the results as a wake-up call for the public and care providers alike. (2021-02-05)

Report shows alcohol consumption linked to portion of cancer incidence and mortality
A new study finds that alcohol consumption accounts for a considerable portion of cancer incidence and mortality in all 50 states and the District of Columbia. (2021-01-19)

COVID-19 likely lingered longer than reported in Wuhan
Wuhan City in China was the first place to report COVID-19 in the world and--between December 2019 and May 2020--caused nearly two-thirds of all COVID-19 cases in China. Now, researchers reporting in PLOS Neglected Tropical Diseases have tested more than 60,000 healthy individuals in China for SARS-CoV-2 antibodies and concluded that thousands of Wuhan residents were infected with asymptomatic cases of COVID-19 after the infection was believed to be under control in China. (2021-01-07)

Study reports patient-reported loss of smell in 86% of mild COVID-19 cases
A reduced sense of smell, or olfactory dysfunction, is one of the most common symptoms of COVID-19. A recent study published the Journal of Internal Medicine has examined it prevalence and recovery in patients with varying degrees of severity of COVID-19. (2021-01-06)

Study suggests reporting of sexually transmitted infections may be impacted by COVID-19
With the health care community heavily focused on COVID-19 since the first quarter of 2020, there have been concerns that reporting of other diseases -- and the resulting data that enables them to be more effectively treated and controlled -- may have been impacted. For example, little is known about how the pandemic may have affected the reporting of sexually transmitted infections (STIs). (2020-12-15)

Wuhan mass screening identifies hundreds of asymptomatic cases
A mass screening programme of 10 million Wuhan residents identified 300 asymptomatic cases in May, but none were infectious - according to a new study. They found no 'viable' virus in the asymptomatic cases and the close contacts of these positive asymptomatic cases did not test positive. But these findings do not show that the virus can't be passed on by asymptomatic carriers. Rather mask-wearing, hand washing, social distancing and lockdown have helped reduce Covid-19 virulence. (2020-11-30)

COVID-19 cases could nearly double before Biden takes office
President-elect Joe Biden has signaled that fighting the COVID-19 pandemic will be an immediate priority for his administration. But Inauguration Day is still two months away. The number of confirmed COVID-19 cases are likely to increase to 20 million by the end of January, nearly doubling the current level of 11.4 million cases, predicts a Washington University in St. Louis COVID-19 forecasting model. (2020-11-23)

Diagnosing the cause of exercise-induced respiratory symptoms
Exercise?induced respiratory symptoms are common in childhood, and it can be difficult to diagnose their cause. A study published in Pediatric Pulmonology found that the diagnoses proposed by primary care physicians are often not the same as the final diagnoses after specialist referrals. (2020-11-18)

Formal community forest management policies often lead to reduced access, resource rights
The most comprehensive global analysis of community forestry ever undertaken shows that government policies formalizing local residents' land access and resource rights often backfire by resulting in less access and weakened rights. (2020-11-09)

Social distancing may have saved more than 59,000 u.s. Lives if implemented two weeks earlier
Implementing social distancing, business closures, and other non-pharmaceutical interventions (NPIs) in the U.S. two weeks sooner, during the earliest stages of the COVID-19 pandemic, may have (2020-11-06)

Mask mandates shown to significantly reduce spread of COVID-19
A new study by Simon Fraser University researchers has found clear evidence that wearing a mask can have a significant impact on the spread of COVID-19. (2020-10-06)

Investigation: FDA oversight of clinical trials is lax, slow, secretive and getting worse
The US Food and Drug Administration (FDA) oversees most clinical research in the United States, ensuring the integrity of trial data and the safety of study participants -- including most recently a number of high-stakes vaccine and drug trials for COVID-19. (2020-10-01)

Data from two Indian states reveal SARS-CoV-2 impacts in a resource-limited setting
In two states in India, Tamil Nadu and Andhra Pradesh, COVID-19 cases and deaths have been more heavily concentrated in younger cohorts than is seen in high-income countries, among other trends. (2020-09-30)

Scientists discover bacterium linked to deadly childhood disorder
Scientists at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health have discovered bacteria linked to post-infectious hydrocephalus (PIH), the most common cause of pediatric hydrocephalus worldwide. Results of the study led by Pennsylvania State University with CII scientists and clinical colleagues in Uganda are published in the journal Science Translational Medicine. (2020-09-30)

Study shows one quarter of hospitalized young patients aged 18-39 years with COVID-19 developed pneumonia
New research to be presented at the ESCMID Conference on Coronavirus Disease (ECCVID, held online from 23-25 September) shows that one quarter of hospitalized younger patients with COVID-19 aged 18-39 years developed pneumonia, underlining the danger the disease represents to young people. (2020-09-17)

Does the Mediterranean diet protect against rheumatoid arthritis?
Previous research has demonstrated a variety of health benefits associated with the Mediterranean diet, which is rich in olive oil, cereals, fruit and vegetables, fish, and a moderate amount of dairy, meat, and wine. Now results from an analysis published in Arthritis & Rheumatology suggest that the diet may also help prevent rheumatoid arthritis in individuals who smoke or used to smoke. (2020-09-10)

Aspirated consonants may promote the spread of COVID-19, RUDN University linguist says
According to a linguist from RUDN University, the number of COVID-19 cases in a country might be related to the existence of aspirated consonants in its main language of communication. This data can help create more accurate models to describe the spread of COVID-19. The results of the study were published in the Medical Hypotheses journal. (2020-08-30)

Study hopes to encourage use of new technology to reduce errors in DNA testing
The paper published in PLOS Genetics points out that existing problems of paternity testing have occurred over many years. (2020-08-17)

Delaying prostate cancer radiation therapy offers room for flexibility in pandemic peak
A new study by investigators from Brigham and Women's Hospital found that for men with unfavorable intermediate-risk or high-risk localized prostate cancer, who are receiving radiation and hormone therapy, delaying radiation while remaining on hormone therapy is unlikely to impact survival. (2020-08-13)

Early spread of COVID-19 appears far greater than initially reported
Patients with undiagnosed flu symptoms who actually had COVID-19 last winter were among thousands of undetected early cases of the disease at the beginning of this year. In a new paper in The Lancet's open-access journal EClinicalMedicine, epidemiological researchers from The University of Texas at Austin estimated COVID-19 to be far more widespread in Wuhan, China, and Seattle, Washington, weeks ahead of lockdown measures in each city. (2020-08-12)

Gout diagnoses rising worldwide
The prevalence of gout -- a form of arthritis characterized by severe pain, redness, and tenderness in joints--increased across the world at an alarming rate from 1990 to 2017, according to an analysis published in Arthritis & Rheumatology. (2020-08-05)

COVID-19 study confirms low transmission in educational settings
New research from University of Sydney finds COVID-19 transmission rates in NSW schools and early childcare education and care settings were minimal, particularly between children and from children to adults. (2020-08-03)

Minimally invasive percutaneous treatment for osteoid osteoma of the spine
Osteoid osteomas are benign but painful bone-forming tumors usually involving long bones, with localization at the spine in 10-20% of the cases. In the last years, percutaneous radiofrequency ablation has been proposed as a new mini-invasive technique for the treatment of osteoid osteomas. (2020-07-31)

Injury patterns may help differentiate between accidents and physical abuse in elderly patients, new study finds
The signs of physical abuse among elderly people can be challenging for health care professionals to recognize, resulting in as few as one in 24 cases being reported to authorities. However, a new study in Annals of Emergency Medicine explores injury patterns and characteristics to help experts spot key differences between abuse and unintentional injury. (2020-07-28)

Scientists chart SARS-CoV-2 origin and transmission in Brazil, harboring one of fastest growing COVID-19 epidemics in the world
A team of Brazilian and European scientists has determined the transmission rates and out-of-country origins of predominant SARS-CoV-2 strains currently circulating in Brazil, which harbors one of the fastest growing COVID-19 epidemics in the world. (2020-07-23)

COVID-19: Cuba offers UK salutary lesson in 'shoe-leather' epidemiology
Cuba's successful containment of COVID-19 through door-to-door screening of every home in the country, shows how 'shoe-leather' epidemiology could have averted the dramatic failure of the UK's response to the pandemic. In Cuba there have been 2,173 confirmed cases and 83 deaths, with no reported deaths throughout the first week in June, 2020. (2020-07-14)

Single-cell RNA sequencing outlines the immune landscape of severe COVID-19
A new single-cell RNA sequencing analysis of more than 59,000 cells from three different patient cohorts provides a detailed look at patients' immune responses to severe cases of COVID-19. (2020-07-10)

COVID-19 cases and deaths in federal and state prisons significantly higher than in US population
A new analysis led by researchers at Johns Hopkins Bloomberg School of Public Health found that the number of US prison residents who tested positive for COVID-19 was 5.5 times higher than the general US population. (2020-07-08)

Treating leukaemia more effectively
Acute lymphoblastic leukaemia (ALL) is the most common kind of cancer in children. T-ALL, a subtype that resembles T-lymphocytes, can be treated successfully with the drug nelarabine. The drug has not been successful, however, with B-ALL, a subtype resembling B-lymphocytes. This has puzzled oncologists sinced the 1980's. Now, an international research team headed by Goethe University and the University of Kent has discovered the reason: B-ALL cells contain the enzyme SAMHD1, which deactivates the drug. (2020-06-24)

Initial COVID-19 infection rate may be 80 times greater than originally reported
A new study from Penn State estimates that the number of early COVID-19 cases in the U.S. may have been more than 80 times greater and doubled nearly twice as fast as originally believed. (2020-06-22)

Influenza-like illness surveillance reveals spike in undetected COVID-19 cases in March
A surge in flu-like infections in the US in March of 2020 suggests that the likely number of COVID-19 cases was far larger than official estimates, according to a new study of existing surveillance networks for influenza-like infections (ILIs). (2020-06-22)

COVID-19 could be a seasonal illness
A study conducted in Sydney, Australia, during the early epidemic stage of COVID-19 has found an association between lower humidity and an increase in locally acquired positive cases. Researchers discovered a 1 percent decrease in humidity could increase the number of COVID-19 cases by 6 percent. (2020-06-01)

First cases of COVID-19 in New York City primarily from European and US sources
In New York City, the first confirmed COVID-19 cases arose mostly through untracked transmission of the virus from Europe and other parts of the United States, a new molecular epidemiology study of 84 patients reports. (2020-05-29)

New model predicts the peaks of the COVID-19 pandemic
This week in the journal Frontiers, researchers describe a single function that accurately describes all existing available data on active COVID-19 cases and deaths -- and predicts forthcoming peaks. (2020-05-29)

High rate of blood clots in COVID-19
COVID-19 is associated with a high incidence of venous thromboembolism, blood clots in the venous circulation, according to a study conducted by researchers at Brighton and Sussex Medical School (BSMS), UK. (2020-05-19)

Impacts of different social distancing interventions detectable two weeks later, shows German modeling study
In Germany, growth of COVID-19 cases declined after a series of three social distancing interventions, detectable at a two-week delay following each intervention, but only after the third- a far-reaching contact ban -- did cases decline significantly. (2020-05-15)

Immune responses hint why some children get milder RSV infections than others
By studying a cohort of 190 children, a research team has discovered important clues that could help explain why some children with respiratory syncytial virus (RSV) infections get mild cases while others get more severe disease and require hospitalization. (2020-04-22)

Newborns infected with COVID-19 in China experienced mild symptoms
Researchers have identified a total of four cases of newborn babies with COVID-19 infection in China. In all cases the babies experienced only mild symptoms with none requiring intensive care or mechanical ventilation according to research published in in the European Respiratory Journal today (Thursday). (2020-04-08)

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